@article{FischerMayerSchollImholtetal.2018,
  author    = {Fischer, Stefan and Mayer-Scholl, Anne and Imholt, Christian and Spierling, Nastasja G. and Heuser, Elisa and Schmidt, Sabrina and Reil, Daniela and Rosenfeld, Ulrike M. and Jacob, Jens and N{\"o}ckler, Karsten and Ulrich, Rainer G.},
  title     = {Leptospira genomospecies and sequence type prevalence in small mammal populations in Germany},
  series = {Vector-Borne and Zoonotic Diseases},
  volume    = {18},
  journal   = {Vector-Borne and Zoonotic Diseases},
  number    = {4},
  publisher = {Liebert},
  address   = {New Rochelle},
  issn      = {1530-3667},
  doi       = {10.1089/vbz.2017.2140},
  pages     = {188 -- 199},
  year      = {2018},
  abstract  = {Leptospirosis is a worldwide emerging infectious disease caused by zoonotic bacteria of the genus Leptospira. Numerous mammals, including domestic and companion animals, can be infected by Leptospira spp., but rodents and other small mammals are considered the main reservoir. The annual number of recorded human leptospirosis cases in Germany (2001-2016) was 25-166. Field fever outbreaks in strawberry pickers, due to infection with Leptospira kirschneri serovar Grippotyphosa, were reported in 2007 and 2014. To identify the most commonly occurring Leptospira genomospecies, sequence types (STs), and their small mammal host specificity, a monitoring study was performed during 2010-2014 in four federal states of Germany. Initial screening of kidney tissues of 3,950 animals by PCR targeting the lipl32 gene revealed 435 rodents of 6 species and 89 shrews of three species positive for leptospiral DNA. PCR-based analyses resulted in the identification of the genomospecies L. kirschneri (62.7\%), Leptospira interrogans (28.3\%), and Leptospira borgpetersenii (9.0\%), which are represented by four, one, and two STs, respectively. The average Leptospira prevalence was highest (approximate to 30\%) in common voles (Microtus arvalis) and field voles (Microtus agrestis). Both species were exclusively infected with L. kirschneri. In contrast, in bank voles (Myodes glareolus) and yellow-necked mice (Apodemus flavicollis), DNA of all three genomospecies was detected, and in common shrews (Sorex araneus) DNA of L. kirschneri and L. borgpetersenii was identified. The association between individual infection status and demographic factors varied between species; infection status was always positively correlated to body weight. In conclusion, the study confirmed a broad geographical distribution of Leptospira in small mammals and suggested an important public health relevance of common and field voles as reservoirs of L. kirschneri. Furthermore, the investigations identified seasonal, habitat-related, as well as individual influences on Leptospira prevalence in small mammals that might impact public health.},
  language  = {en}
}
@article{FischerSpierlingHeuseretal.2018,
  author    = {Fischer, Stefan and Spierling, Nastasja G. and Heuser, Elisa and Kling, Christopher and Schmidt, Sabrina and Rosenfeld, Ulrike M. and Reil, Daniela and Imholt, Christian and Jacob, Jens and Ulrich, Rainer G. and Essbauer, Sandra},
  title     = {High prevalence of Rickettsia helvetica in wild small mammal populations in Germany},
  series = {Ticks and Tick-borne Diseases},
  volume    = {9},
  journal   = {Ticks and Tick-borne Diseases},
  number    = {3},
  publisher = {Elsevier GMBH},
  address   = {M{\"u}nchen},
  issn      = {1877-959X},
  doi       = {10.1016/j.ttbdis.2018.01.009},
  pages     = {500 -- 505},
  year      = {2018},
  abstract  = {Since the beginning of the 21st century, spotted fever rickettsioses are known as emerging diseases worldwide. Rickettsiae are obligately intracellular bacteria transmitted by arthropod vectors. The ecology of Rickettsia species has not been investigated in detail, but small mammals are considered to play a role as reservoirs. Aim of this study was to monitor rickettsiae in wild small mammals over a period of five years in four federal states of Germany. Initial screening of ear pinna tissues of 3939 animals by Pan-Rick real-time PCR targeting the citrate synthase (gltA) gene revealed 296 rodents of seven species and 19 shrews of two species positive for rickettsial DNA. Outer membrane protein gene (ompB, ompAIV) PCRs based typing resulted in the identification of three species: Rickettsia helvetica (90.9\%) was found as the dominantly occurring species in the four investigated federal states, but Rickettsia felis (7.8\%) and Rickettsia raoultii (1.3\%) were also detected. The prevalence of Rickettsia spp. in rodents of the genus Apodemus was found to be higher (approximately 14\%) than in all other rodent and shrew species at all investigated sites. General linear mixed model analyses indicated that heavier (older) individuals of yellow-necked mice and male common voles seem to contain more often rickettsial DNA than younger ones. Furthermore, rodents generally collected in forests in summer and autumn more often carried rickettsial DNA. In conclusion, this study indicated a high prevalence of R. helvetica in small mammal populations and suggests an age-dependent increase of the DNA prevalence in some of the species and in animals originating from forest habitats. The finding of R. helvetica and R. felis DNA in multiple small mammal species may indicate frequent trans-species transmission by feeding of vectors on different species. Further investigations should target the reason for the discrepancy between the high rickettsial DNA prevalence in rodents and the so far almost absence of clinical apparent human infections.},
  language  = {en}
}
@misc{GroezingerJuetteJuetteetal.2005,
  author    = {Gr{\"o}zinger, Elvira and J{\"u}tte, Daniel and J{\"u}tte, Robert and Knufinke, Ulrich and Marquart, Susanne and Meroz, Ronit and Miller, Gabriel and Nemtsov, Jascha and Panagiotidis, Elena and Powels-Niami, Sylvia and Reininghaus, Moritz and Riemer, Nathanael and Rosenfeld, Ulrike M. and Strehlen, Martina and Voigts, Manfred and Werner, Petra},
  title     = {PaRDeS : Zeitschrift der Vereinigung f{\"u}r J{\"u}dische Studien e.V.},
  number    = {11},
  editor    = {Riemer, Nathanael and Dubrau, Alexander},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-939469-80-3},
  issn      = {1862-7684},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-6772},
  year      = {2005},
  abstract  = {Aus dem Inhalt dieser Ausgabe: Artikel und Miszellen: Sylvia Powels-Niami: Die Samaritaner, ihre Geschichte, Religion und Literatur, Ronit Meroz: Der Aufbau des Buches Sohar, Nathanael Riemer: „Der Rabbiner" - eine vergessene Zeitschrift eines christlichen Hebraisten, Ulrich Knufinke: J{\"u}dische Friedhofsbauten um 1800 in Deutschland : Architektur als Spiegel der Auseinandersetzungen um Haskala, „Emanzipation" und „Assimilation", Manfred Voigts: Die „Freie Wissenschaftliche Vereinigung" - eine antiantisemitische Studentenverbindung, Susanne Marquardt/Petra Werner: Katalogisierung von Judaica und Hebraica am Beispiel Berlin-Brandenburger Bibliotheken Tagungen: J{\"u}dische Identit{\"a}ten in Ostmitteleuropa im 19. und 20. Jahrhundert im Wandel (Elena Panagiotidis), 700 Jahre Juden in Krakau (Elvira Gr{\"o}zinger), J{\"u}disches Archivwesen (Martina Strehlen), Geschichte und geistige Physiognomie der Veitel Heine Ephraimschen Lehranstalt Berlin (Moritz Reininghaus) Rezensionen: Un beau livre d'histoires. Eyn sh{\"o}n Mayse bukh (Nathanel Riemer), Juliette Guilbaud, Nicolas Le Moigne, Thomas L{\"u}ttenberg (Hrsg.): Normes culturelles et construction de la d{\´e}viance (Robert J{\"u}tte), Monika Preuß, „...aber die Krone des guten Namens {\"u}berragt sie." (Robert J{\"u}tte), Jeremy Barham (Hrsg.): Perspectives on Gustav Mahler; Philip V. Bohlman: J{\"u}dische Volksmusik; Tina Fr{\"u}hauf: Orgel und Orgelmusik in deutsch-j{\"u}discher Kultur (Daniel J{\"u}tte), „Aus Kindern wurden Briefe. Die Rettung j{\"u}discher Kinder aus Nazi-Deutschland". Hrsg. v. Gudrun Maierhof, Chana Sch{\"u}tz, Hermann Simon (Elvira Gr{\"o}zinger), Meike Gotham: Die Rechtsnation und ihr Staat (Gabriel Miller), Matthias N. Lorenz: „Auschwitz dr{\"a}ngt uns auf einen Fleck" (Elvira Gr{\"o}zinger) J{\"u}dische Studien in aller Welt: Eindr{\"u}cke von Forschungsreisen nach Moskau, Jerusalem und New York (Jascha Nemtsov)},
  subject      = {Judentum},
  language  = {de}
}
@article{ReilImholtRosenfeldetal.2017,
  author    = {Reil, Daniela and Imholt, Christian and Rosenfeld, Ulrike M. and Drewes, Stephan and Fischer, S. and Heuser, Emil and Petraityte-Burneikiene, Rasa and Ulrich, R. G. and Jacob, J.},
  title     = {Validation of the Puumala virus rapid field test for bank voles in Germany},
  series = {Epidemiology and infection},
  volume    = {145},
  journal   = {Epidemiology and infection},
  number    = {3},
  publisher = {Cambridge Univ. Press},
  address   = {New York},
  issn      = {0950-2688},
  doi       = {10.1017/S0950268816002557},
  pages     = {434 -- 439},
  year      = {2017},
  abstract  = {Puumala virus (PUUV) causes many human infections in large parts of Europe and can lead to mild to moderate disease. The bank vole (Myodes glareolus) is the only reservoir of PUUV in Central Europe. A commercial PUUV rapid field test for rodents was validated for bank-vole blood samples collected in two PUUV-endemic regions in Germany (North Rhine-Westphalia and Baden-Wurttemberg). A comparison of the results of the rapid field test and standard ELISAs indicated a test efficacy of 93-95\%, largely independent of the origin of the antigens used in the ELISA. In ELISAs, reactivity for the German PUUV strain was higher compared to the Swedish strain but not compared to the Finnish strain, which was used for the rapid field test. In conclusion, the use of the rapid field test can facilitate short-term estimation of PUUV seroprevalence in bank-vole populations in Germany and can aid in assessing human PUUV infection risk.},
  language  = {en}
}
@misc{ReilRosenfeldImholtetal.2017,
  author    = {Reil, Daniela and Rosenfeld, Ulrike M. and Imholt, Christian and Schmidt, Sabrina and Ulrich, Rainer G. and Eccard, Jana and Jacob, Jens},
  title     = {Puumala hantavirus infections in bank vole populations},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {957},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-43123},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-431232},
  pages     = {15},
  year      = {2017},
  abstract  = {Background In Europe, bank voles (Myodes glareolus) are widely distributed and can transmit Puumala virus (PUUV) to humans, which causes a mild to moderate form of haemorrhagic fever with renal syndrome, called nephropathia epidemica. Uncovering the link between host and virus dynamics can help to prevent human PUUV infections in the future. Bank voles were live trapped three times a year in 2010-2013 in three woodland plots in each of four regions in Germany. Bank vole population density was estimated and blood samples collected to detect PUUV specific antibodies. Results We demonstrated that fluctuation of PUUV seroprevalence is dependent not only on multi-annual but also on seasonal dynamics of rodent host abundance. Moreover, PUUV infection might affect host fitness, because seropositive individuals survived better from spring to summer than uninfected bank voles. Individual space use was independent of PUUV infections. Conclusions Our study provides robust estimations of relevant patterns and processes of the dynamics of PUUV and its rodent host in Central Europe, which are highly important for the future development of predictive models for human hantavirus infection risk.},
  language  = {en}
}
@article{ReilRosenfeldImholtetal.2017,
  author    = {Reil, Daniela and Rosenfeld, Ulrike M. and Imholt, Christian and Schmidt, Sabrina and Ulrich, Rainer G. and Eccard, Jana and Jacob, Jens},
  title     = {Puumala hantavirus infections in bank vole populations},
  series = {BMC ecology},
  volume    = {17},
  journal   = {BMC ecology},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1472-6785},
  doi       = {10.1186/s12898-017-0118-z},
  pages     = {13},
  year      = {2017},
  abstract  = {Background In Europe, bank voles (Myodes glareolus) are widely distributed and can transmit Puumala virus (PUUV) to humans, which causes a mild to moderate form of haemorrhagic fever with renal syndrome, called nephropathia epidemica. Uncovering the link between host and virus dynamics can help to prevent human PUUV infections in the future. Bank voles were live trapped three times a year in 2010-2013 in three woodland plots in each of four regions in Germany. Bank vole population density was estimated and blood samples collected to detect PUUV specific antibodies. Results We demonstrated that fluctuation of PUUV seroprevalence is dependent not only on multi-annual but also on seasonal dynamics of rodent host abundance. Moreover, PUUV infection might affect host fitness, because seropositive individuals survived better from spring to summer than uninfected bank voles. Individual space use was independent of PUUV infections. Conclusions Our study provides robust estimations of relevant patterns and processes of the dynamics of PUUV and its rodent host in Central Europe, which are highly important for the future development of predictive models for human hantavirus infection risk},
  language  = {en}
}