@article{SchwarzeSprengerRiemer2020, author = {Schwarze, Thomas and Sprenger, Tobias and Riemer, Janine}, title = {1,2,3-Triazol-1,4-diyl-Fluoroionophores for Zn2+, Mg2+ and Ca2+ based on Fluorescence Intensity Enhancements in Water}, series = {ChemistrySelect}, volume = {5}, journal = {ChemistrySelect}, number = {41}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {2365-6549}, doi = {10.1002/slct.202003695}, pages = {12727 -- 12735}, year = {2020}, abstract = {Herein, we represent cation-responsive fluorescent probes for the divalent cations Zn2+, Mg2+ and Ca2+, which show cation-induced fluorescence enhancements (FE) in water. The Zn2+-responsive probes Zn1, Zn2, Zn3 and Zn4 are based on o-aminoanisole-N,N-diacetic acid (AADA) derivatives and show in the presence of Zn2+ FE factors of 11.4, 13.9, 6.1 and 8.2, respectively. Most of all, Zn1 and Zn2 show higher Zn2+ induced FE than the regioisomeric triazole linked fluorescent probes Zn3 and Zn4, respectively. In this set, ZN2 is the most suitable probe to detect extracellular Zn2+ levels. For the Mg2+-responsive fluorescent probes Mg1, Mg2 and Mg3 based on o-aminophenol-N,N,O-triacetic acid (APTRA) derivatives, we also found that the regioisomeric linkage influences the fluorescence responds towards Mg2+ (Mg1+100 mM Mg2+ (FEF=13.2) and Mg3+100 mM Mg2+ (FEF=2.1)). Mg2 shows the highest Mg2+-induced FE by a factor of 25.7 and an appropriate K-d value of 3 mM to measure intracellular Mg2+ levels. Further, the Ca2+-responsive fluorescent probes Ca1 and Ca2 equipped with a 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) derivative show high Ca2+-induced FEs (Ca1 (FEF=22.1) and Ca2 (FEF=23.0)). Herein, only Ca1 (K-d=313 nM) is a suitable Ca2+ fluorescent indicator to determine intracellular Ca2+ levels.}, language = {en} } @misc{IvenHansenAndersetal.2020, author = {Iven, Claudia and Hansen, Bernd and Anders, Kristina and Starke, Andreas and Richardt, Kirsten and Pr{\"u}ß, Holger and El Meskioui, Martina and Haase, Tobias and Mahlberg, Lea and Wiehe, Lea and de Beer, Carola and Niepelt Karampamapa, Rebekka and Hofmann, Andrea and Stadie, Nicole and Hanne, Sandra and Thomson, Jenny and Sch{\"a}fer, Blanca and Huttenlauch, Clara and Wartenburger, Isabell and Weiland, Katharina and Wirsam, Anke and Hartung, Julia and Wahl, Michael and Unger, Julia and Buschmann, Anke and Seefeld, Martin and Bethge, Anita and Fieder, Nora and Rahman, Rasha Abdel and Nousair, Iman and Klassert, Annegret and Wellmann, Caroline and Verbree, Rahel and van Rij, Jacolien and Sprenger, Simone and M{\"a}hl, Anna Luisa and Schneider, Kathleen and Kutz, Anne and Kaps, Hella and Frank, Ulrike and Brekeller, Sophie and Ryll, Katja}, title = {Spektrum Patholinguistik Band 12. Schwerpunktthema: Weg(e) mit dem Stottern: Therapie und Selbsthilfe f{\"u}r Kinder und Erwachsene}, series = {Spektrum Patholinguistik}, journal = {Spektrum Patholinguistik}, number = {12}, editor = {Breitenstein, Sarah and Burmester, Juliane and Yetim, {\"O}zlem and Fritzsche, Tom}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-479-1}, issn = {1866-9085}, doi = {10.25932/publishup-43700}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-437002}, pages = {viii, 257}, year = {2020}, abstract = {Das 12. Herbsttreffen Patholinguistik mit dem Schwerpunktthema »Weg(e) mit dem Stottern: Therapie und Selbsthilfe f{\"u}r Kinder und Erwachsene« fand am 24.11.2018 in Potsdam statt. Das Herbsttreffen wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Der vorliegende Tagungsband beinhaltet die Vortr{\"a}ge zum Schwerpunktthema sowie Beitr{\"a}ge der Posterpr{\"a}sentationen zu weiteren Themen aus der sprachtherapeutischen Forschung und Praxis.}, language = {de} }