@misc{ZohselHohmSchmidtetal.2017,
  author    = {Zohsel, Katrin and Hohm, Erika and Schmidt, Martin H. and Brandeis, Daniel and Banaschewski, Tobias and Laucht, Manfred},
  title     = {Langfristige Folgen fr{\"u}her psychosozialer Risiken},
  series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {609},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-43342},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-433424},
  pages     = {203 -- 209},
  year      = {2017},
  abstract  = {In einer prospektiven L{\"a}ngsschnittstudie wurden Auswirkungen fr{\"u}her psychosozialer Risiken bis ins junge Erwachsenenalter untersucht und dabei die Rolle von affektiver und behavioraler Dysregulation im Kindesalter als vermittelndem Faktor {\"u}berpr{\"u}ft. Drei Monate nach der Geburt wurde das Vorliegen von 11 psychosozialen Belastungsfaktoren erfasst. Im Alter von 8 - 15 Jahren wurde dreimal das Child Behavior Checklist-Dysregulationsprofil (CBCL-DP) erhoben. Mit 25 Jahren wurde ein Strukturiertes Klinisches Interview durchgef{\"u}hrt und 309 der Teilnehmer f{\"u}llten den Young Adult Self-Report aus. Fr{\"u}he psychosoziale Risiken gingen mit einem erh{\"o}hten Risiko f{\"u}r das Vorliegen eines Substanzmissbrauchs im jungen Erwachsenenalter sowie mit erh{\"o}htem externalisierendem und internalisierendem Problemverhalten einher. Der Zusammenhang zwischen fr{\"u}hen psychosozialen Risiken und sp{\"a}terem externalisierendem bzw. internalisierendem Problemverhalten wurde durch das CBCL-DP vermittelt.},
  language  = {de}
}
@misc{HohmLauchtZohseletal.2017,
  author    = {Hohm, Erika and Laucht, Manfred and Zohsel, Katrin and Schmidt, Martin H. and Esser, G{\"u}nter and Brandeis, Daniel and Banaschewski, Tobias},
  title     = {Resilienz und Ressourcen im Verlauf der Entwicklung},
  series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {608},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-43307},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-433072},
  pages     = {230 -- 239},
  year      = {2017},
  abstract  = {Anhand von Daten der Mannheimer Risikokinderstudie, die sich mit der langfristigen Entwicklung von Kindern mit unterschiedlichen Risikobelastungen besch{\"a}ftigt, wird gezeigt, wie Schutzfaktoren aufseiten des Kindes und seines famili{\"a}ren Umfelds im Verlauf der Entwicklung wirksam werden und zur Entstehung von Resilienz beitragen k{\"o}nnen. Eine besondere Rolle kommt dabei positiven fr{\"u}hen Eltern-Kind-Beziehungen zu (sowohl Mutter- als auch Vater-Kind-Interaktionen). Daneben spielen auch Interaktionserfahrungen im Alter von zwei Jahren des Kindes eine bedeutsame Rolle; diese sch{\"u}tzen Risikokinder davor, eine ung{\"u}nstige Entwicklung zu nehmen und tragen dazu bei, dass sich Kinder, die in psychosozialen Hochrisikofamilien aufwachsen, trotz ung{\"u}nstiger „Startbedingungen" positiv entwickeln. Neben Merkmalen der sozialen Umwelt nehmen auch sprachliche, sozial-emotionale und internale Kompetenzen des Kindes im Entwicklungsverlauf eine wichtige Rolle ein. Diese Kompetenzen erm{\"o}glichen es Risikokindern auch unter widrigen Lebensumst{\"a}nden (psychosoziale Hochrisikofamilien, Aufwachsen in Armutsverh{\"a}ltnissen) erfolgreich zu bestehen. Dar{\"u}ber hinaus zeigt die Arbeit, dass Resilienz ein Pers{\"o}nlichkeitsmerkmal ist, das ab dem fr{\"u}hen Erwachsenenalter eine hohe Stabilit{\"a}t besitzt. Mit diesen Befunden verweist die Arbeit auf die große Bedeutung der Resilienz bei der Vorhersage der langfristigen Entwicklung von Risikokindern.},
  language  = {de}
}
@misc{ZohselHohmSchmidtetal.2017,
  author    = {Zohsel, Katrin and Hohm, Erika and Schmidt, Martin H. and Brandeis, Daniel and Banaschewski, Tobias and Laucht, Manfred},
  title     = {Die langfristigen Auswirkungen von Fr{\"u}hgeburtlichkeit auf kognitive Entwicklung und Schulerfolg},
  series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {701},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-43353},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-433536},
  pages     = {11},
  year      = {2017},
  abstract  = {In einer prospektiven L{\"a}ngsschnittstudie wurde der Zusammenhang zwischen fr{\"u}her Responsivit{\"a}t der Mutter und kognitiver Entwicklung ihrer fr{\"u}h- bzw. reifgeborenen Kinder untersucht. Im Alter von drei Monaten wurde daf{\"u}r die Mutter-Kind-Interaktion mittels Verhaltensbeobachtung erfasst. Bei n=351 der teilnehmenden Kinder (101 fr{\"u}hgeboren) wurde die allgemeine Intelligenz (IQ) im Alter von 11 Jahren und bei n=313 (85 fr{\"u}hgeboren) zus{\"a}tzlich der h{\"o}chste erreichte Schulabschluss bis 25 Jahren erhoben. Fr{\"u}hgeborene wiesen mit 11 Jahren einen signifikant niedrigeren IQ als Reifgeborene auf, nachdem f{\"u}r m{\"o}gliche konfundierende Faktoren kontrolliert worden war. Nur bei Fr{\"u}h-, nicht aber bei Reifgeborenen zeigte sich ein signifikanter positiver Zusammenhang zwischen m{\"u}tterlicher Responsivit{\"a}t und IQ. F{\"u}r die Wahrscheinlichkeit einen h{\"o}heren Schulabschluss (mind. Fachabitur) zu erreichen, fand sich weder ein signifikanter Effekt von Fr{\"u}hgeburtlichkeit noch von m{\"u}tterlicher Responsivit{\"a}t.},
  language  = {de}
}
@article{HsuSchmidtKempfetal.2018,
  author    = {Hsu, Hsiang-Wen and Schmidt, J{\"u}rgen and Kempf, Sascha and Postberg, Frank and Moragas-Klostermeyer, Georg and Seiss, Martin and Hoffmann, Holger and Burton, Marcia and Ye, ShengYi and Kurth, William S. and Horanyi, Mihaly and Khawaja, Nozair and Spahn, Frank and Schirdewahn, Daniel and Moore, Luke and Cuzzi, Jeff and Jones, Geraint H. and Srama, Ralf},
  title     = {In situ collection of dust grains falling from Saturn's rings into its atmosphere},
  series = {Science},
  volume    = {362},
  journal   = {Science},
  number    = {6410},
  publisher = {American Assoc. for the Advancement of Science},
  address   = {Washington},
  issn      = {0036-8075},
  doi       = {10.1126/science.aat3185},
  pages     = {49 -- +},
  year      = {2018},
  abstract  = {Saturn's main rings are composed of >95\% water ice, and the nature of the remaining few percent has remained unclear. The Cassini spacecraft's traversals between Saturn and its innermost D ring allowed its cosmic dust analyzer (CDA) to collect material released from the main rings and to characterize the ring material infall into Saturn. We report the direct in situ detection of material from Saturn's dense rings by the CDA impact mass spectrometer. Most detected grains are a few tens of nanometers in size and dynamically associated with the previously inferred "ring rain." Silicate and water-ice grains were identified, in proportions that vary with latitude. Silicate grains constitute up to 30\% of infalling grains, a higher percentage than the bulk silicate content of the rings.},
  language  = {en}
}
@article{VianaWackermannFurtadoEsseretal.2006,
  author    = {Viana-Wackermann, Paula C. and Furtado, Erikson F. and Esser, G{\"u}nter and Schmidt, Martin H. and Laucht, Manfred},
  title     = {Lower P300 amplitude in eight-year-old offspring of alcoholic fathers with a delinquent history},
  issn      = {0940-1334},
  doi       = {10.1007/s00406-006-0709-8},
  year      = {2006},
  abstract  = {The aim of the present study was to investigate the P300 amplitude as a possible vulnerability marker in children of alcoholic (COA) fathers with and without paternal delinquency. Event-related potentials (ERPs) of 122 children aged 8 years (63 boys, 59 girls) were compared depending on father's alcoholism subtype: 30 COAs without paternal delinquency, 10 COAs with paternal delinquency, and 82 children of non-alcoholic and non-delinquent fathers. ERPs were recorded from Fz, Cz, and Pz, using an auditory oddball paradigm. Sinus tones of 60 dB HL were presented binaurally at 1,000 Hz (standard stimulus) and 2,000 Hz (target stimulus), at a relative frequency ratio of 80:20. Two trial blocks of 250 stimuli each were collected. Results indicated that only COAs with paternal delinquency displayed significant differences from the control group, characterized by reduced P300 amplitude at frontal site and in the second trial block. Thus, the combination of fathers' alcoholism and delinquency was more likely to relate to attenuated P300 amplitude in the offspring than paternal alcoholism alone. Our results suggest that both alcoholic and delinquent family history appear to play a role in P300 amplitude reduction in the offspring.},
  language  = {en}
}
@article{DamesZimmermannSchmidtetal.2006,
  author    = {Dames, Petra and Zimmermann, Bernhard and Schmidt, Ruth and Rein, Julia and Voss, Martin and Schewe, Bettina and Walz, Bernd and Baumann, Otto},
  title     = {cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands},
  issn      = {0027-8424},
  doi       = {10.1073/pnas.0600011103},
  year      = {2006},
  abstract  = {Reversible assembly of the V0V1 holoenzyme from V-0 and V-1 subcomplexes is a widely used mechanism for regulation of vacuolar-type H+-ATPases (V-ATPases) in animal cells. in the blowfly (Calliphora vicina) salivary gland, V- ATPase is located in the apical membrane of the secretory cells and energizes the secretion of a KCl-rich saliva in response to the hormone serotonin. We have examined whether the CAMP pathway, known to be activated by serotonin, controls V-ATPase assembly and activity. Fluorescence measurements of pH changes at the luminal surface of isolated glands demonstrate that CAMP, Sp-adenosine-3',5'-cyclic monophosphorothioate, or forskolin, similar to serotonin, cause V-ATPase-dependent luminal acidification. In addition, V-ATPase-dependent ATP hydrolysis increases upon treatment with these agents. Immunofluorescence microscopy and pelleting assays have demonstrated further that V, components become translocated from the cytoplasm to the apical membrane and V-ATPase holoenzymes are assembled at the apical membrane during conditions that increase intracellular cAMP. Because these actions occur without a change in cytosolic Ca2+, our findings suggest that the cAMP pathway mediates the reversible assembly and activation of V-ATPase molecules at the apical membrane upon hormonal stimulus},
  language  = {en}
}
@article{LauchtHohmEsseretal.2007,
  author    = {Laucht, Manfred and Hohm, E. and Esser, G{\"u}nter and Schmidt, Martin H. and Becker, Katja},
  title     = {Association between ADHD and smoking in adolescence : shared genetic, environmental and psychopathological factors},
  issn      = {0300-9564},
  doi       = {10.1007/s00702-007-0703-y},
  year      = {2007},
  abstract  = {The present study aimed to examine the extent to which the co-occurrence of ADHD and smoking in adolescents could be attributed to common genetic, environmental and psychopathological factors. Data are from an ongoing prospective study of the outcome of early risk factors. At age 15 years, 305 adolescents completed self-report questionnaires measuring tobacco consumption and deviant peer affiliations. Lifetime psychiatric diagnoses were obtained using standardized interviews. DNA was genotyped for the dopamine D4 receptor (DRD4) gene exon III polymorphism. Adolescents with a lifetime diagnosis of ADHD displayed significantly higher smoking activity than non-ADHD controls. A major component of this association could be accounted for by deviant peer affiliations and the comorbidity with oppositional-defiant and conduct disorder, while a minor part was attributable to DRD4 in males but not in females. These findings suggest that the association of ADHD with smoking relies on risk factors shared by the two behaviors.},
  language  = {en}
}
@article{LauchtHohmEsseretal.2005,
  author    = {Laucht, Manfred and Hohm, E. and Esser, G{\"u}nter and Schmidt, Martin H.},
  title     = {Elevated risk of smoking in children with externalizing disorders},
  issn      = {1616-3443},
  year      = {2005},
  abstract  = {Background: Several studies have reported higher smoking rates among adolescents with externalizing disorders (attention-deficit hyperactivity disorder and conduct disorder) as compared to healthy controls. Objective: To follow the association between childhood externalizing disorders and smoking during development, to determine the type of problems most strongly related to later tobacco use, and to control for the influence of covarying factors. Methods: Participants were from a longitudinal study of a birth cohort of 384 children born with different perinatal and psychosocial risks. Standardized assessments of behavioral disorders between 2 and 11 years and of tobacco use at age 15 were obtained. Results: 15-year-olds with externalizing disorders between 2 and 11 years reported higher tobacco use than those without a history of disorder. This association could be followed back into early childhood and held up even after controlling for covariates. Conclusions: The findings suggest that childhood externalizing disorders may represent an independent risk factor for elevated tobacco use in adolescence},
  language  = {en}
}
@article{LauchtHomEsseretal.2005,
  author    = {Laucht, Manfred and Hom, Erika and Esser, G{\"u}nter and Schmidt, Martin H.},
  title     = {Erh{\"o}htes Raucherrisiko von Kindern mit Aufmerksamkeits- und Verhaltensst{\"o}rungen},
  year      = {2005},
  language  = {de}
}
@article{LayIhleEsseretal.2005,
  author    = {Lay, Barbara and Ihle, Wolfgang and Esser, G{\"u}nter and Schmidt, Martin H.},
  title     = {Juvenile-episodic, continued or adult-onset delinquency? Risk conditions analysed in a cohort of children followed up to the age of 25 years},
  year      = {2005},
  language  = {en}
}