@article{deVeraBoettgerdelaTorreNoetzeletal.2012, author = {de Vera, Jean-Pierre Paul and B{\"o}ttger, Ute and de la Torre N{\"o}tzel, Rosa and Sanchez, Francisco J. and Grunow, Dana and Schmitz, Nicole and Lange, Caroline and H{\"u}bers, Heinz-Wilhelm and Billi, Daniela and Baque, Mickael and Rettberg, Petra and Rabbow, Elke and Reitz, G{\"u}nther and Berger, Thomas and M{\"o}ller, Ralf and Bohmeier, Maria and Horneck, Gerda and Westall, Frances and J{\"a}nchen, Jochen and Fritz, J{\"o}rg and Meyer, Cornelia and Onofri, Silvano and Selbmann, Laura and Zucconi, Laura and Kozyrovska, Natalia and Leya, Thomas and Foing, Bernard and Demets, Rene and Cockell, Charles S. and Bryce, Casey and Wagner, Dirk and Serrano, Paloma and Edwards, Howell G. M. and Joshi, Jasmin Radha and Huwe, Bj{\"o}rn and Ehrenfreund, Pascale and Elsaesser, Andreas and Ott, Sieglinde and Meessen, Joachim and Feyh, Nina and Szewzyk, Ulrich and Jaumann, Ralf and Spohn, Tilman}, title = {Supporting Mars exploration BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology}, series = {Planetary and space science}, volume = {74}, journal = {Planetary and space science}, number = {1}, publisher = {Elsevier}, address = {Oxford}, issn = {0032-0633}, doi = {10.1016/j.pss.2012.06.010}, pages = {103 -- 110}, year = {2012}, abstract = {The Low Earth Orbit (LEO) experiment Biology and Mars Experiment (BIOMEX) is an interdisciplinary and international space research project selected by ESA. The experiment will be accommodated on the space exposure facility EXPOSE-R2 on the International Space Station (ISS) and is foreseen to be launched in 2013. The prime objective of BIOMEX is to measure to what extent biomolecules, such as pigments and cellular components, are resistant to and able to maintain their stability under space and Mars-like conditions. The results of BIOMEX will be relevant for space proven biosignature definition and for building a biosignature data base (e.g. the proposed creation of an international Raman library). The library will be highly relevant for future space missions such as the search for life on Mars. The secondary scientific objective is to analyze to what extent terrestrial extremophiles are able to survive in space and to determine which interactions between biological samples and selected minerals (including terrestrial, Moon- and Mars analogs) can be observed under space and Mars-like conditions. In this context, the Moon will be an additional platform for performing similar experiments with negligible magnetic shielding and higher solar and galactic irradiation compared to LEO. Using the Moon as an additional astrobiological exposure platform to complement ongoing astrobiological LEO investigations could thus enhance the chances of detecting organic traces of life on Mars. We present a lunar lander mission with two related objectives: a lunar lander equipped with Raman and PanCam instruments which can analyze the lunar surface and survey an astrobiological exposure platform. This dual use of testing mission technology together with geo- and astrobiological analyses will significantly increase the science return, and support the human preparation objectives. It will provide knowledge about the Moon's surface itself and, in addition, monitor the stability of life-markers, such as cells, cell components and pigments, in an extraterrestrial environment with much closer radiation properties to the surface of Mars. The combination of a Raman data base of these data together with data from LEO and space simulation experiments, will lead to further progress on the analysis and interpretation of data that we will obtain from future Moon and Mars exploration missions.}, language = {en} } @article{FruscalzoFrommerLonderoetal.2017, author = {Fruscalzo, Arrigo and Frommer, Julia-Marie and Londero, Ambrogio P. and Henze, Andrea and Schweigert, Florian J. and Nofer, Jerzy-Roch and Steinhard, Johannes and Klockenbusch, Walter and Schmitz, Ralf and Raila, Jens}, title = {First trimester TTR-RBP4-ROH complex and angiogenic factors in the prediction of small for gestational age infant's outcome}, series = {Archives of gynecology and obstetrics}, volume = {295}, journal = {Archives of gynecology and obstetrics}, publisher = {Springer}, address = {Heidelberg}, issn = {0932-0067}, doi = {10.1007/s00404-017-4338-4}, pages = {1157 -- 1165}, year = {2017}, abstract = {To study the role of the TTR-RBP4-ROH complex components (transthyretin, serum retinol binding protein, retinol) and of angiogenic factors PlGF (placental growth factor) and sFlt-1 (soluble fms-like tyrosine kinase-1) in pregnancies complicated by small for gestational age infants (SGA). Case control study conducted on maternal serum collected between 11 + 0 to 13 + 6 weeks of gestation. TTR, RBP4, ROH, PlGF and sFlt-1 were measured in SGA patients (birth weight < 10\%) who delivered at term (n = 37) and before 37 weeks of gestation (n = 17) and in a matched control group with uneventful pregnancies (n = 37). We found decreased RBP4 in SGA patients that delivered fetuses < 3\% and in fetuses delivered after the 37 weeks of gestation compared to controls [1.50 (95\% CI 1.40-1.75) vs 1.62 (95\% CI 1.47-1.98), p < 0.05]. Further, we found lower PlGF and sFlt-1 concentrations in SGA that delivered before 37 weeks of gestation compared to controls (respectively, PIGF and sFlt-1: 39.7 pg/ml (95\% CI 32.3-66.3) vs 62.9 pg/ml (95\% CI 45.2-78.4) and 906 pg/ml (95\% CI 727-1626) vs 1610 pg/ml (95\% CI 1088-212), p < 0.05). First trimester maternal serum RBP4 and angiogenic factors PlGF and sFlt-1 can differently predict the timing of delivery of pregnancies complicated by SGA fetuses.}, language = {en} } @inproceedings{SeegererRomeikeTillmannetal.2018, author = {Seegerer, Stefan and Romeike, Ralf and Tillmann, Alexander and Kr{\"o}mker, Detlef and Horn, Florian and Gattinger, Thorsten and Weicker, Karsten and Schmitz, Dennis and Moldt, Daniel and R{\"o}pke, Ren{\´e} and Larisch, Kathrin and Schroeder, Ulrik and Keverp{\"u}tz, Claudia and K{\"u}ppers, Bastian and Striewe, Michael and Kramer, Matthias and Grillenberger, Andreas and Frede, Christiane and Knobelsdorf, Maria and Greven, Christoph}, title = {Hochschuldidaktik der Informatik HDI 2018}, series = {Commentarii informaticae didacticae (CID)}, booktitle = {Commentarii informaticae didacticae (CID)}, number = {12}, editor = {Bergner, Nadine and R{\"o}pke, Ren{\´e} and Schroeder, Ulrik and Kr{\"o}mker, Detlef}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-435-7}, issn = {1868-0844}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-413542}, pages = {161}, year = {2018}, abstract = {Die 8. Fachtagung f{\"u}r Hochschuldidaktik der Informatik (HDI) fand im September 2018 zusammen mit der Deutschen E-Learning Fachtagung Informatik (DeLFI) unter dem gemeinsamen Motto „Digitalisierungswahnsinn? - Wege der Bildungstransformationen" in Frankfurt statt. Dabei widmet sich die HDI allen Fragen der informatischen Bildung im Hochschulbereich. Schwerpunkte bildeten in diesem Jahr u. a.: - Analyse der Inhalte und anzustrebenden Kompetenzen in Informatikveranstaltungen - Programmieren lernen \& Einstieg in Softwareentwicklung - Spezialthemen: Data Science, Theoretische Informatik und Wissenschaftliches Arbeiten Die Fachtagung widmet sich ausgew{\"a}hlten Fragestellungen dieser Themenkomplexe, die durch Vortr{\"a}ge ausgewiesener Experten und durch eingereichte Beitr{\"a}ge intensiv behandelt werden.}, language = {de} } @book{BauerBudaeusGruebetal.2008, author = {Bauer, Hartmut and Bud{\"a}us, Dietrich and Gr{\"u}b, Birgit and Schmitz, Heribert and Reichard, Christoph and Mestwerdt, Thomas and Schenke, Ralf P. and Schaedel, Volker and Paffhausen, Peter}, title = {Verwaltungskooperation : Public Private Partnerships und Public Public Partnerships}, editor = {Bauer, Hartmut and B{\"u}chner, Christiane and Brosius-Gersdorf, Frauke}, isbn = {978-3-940793-68-3}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-27583}, publisher = {Universit{\"a}t Potsdam}, year = {2008}, abstract = {Public Private Partnerships (PPP) sind aktueller denn je: Die Aufgaben der Kommunen werden immer komplexer und lassen sich oft nur meistern, wenn die Last auf mehrere Schultern verteilt wird. F{\"u}r die Kommunen bieten PPPs die Chance zu einer schnelleren, b{\"u}rgern{\"a}heren und bedarfsgerechteren Aufgabenerf{\"u}llung, zur Konzentration auf kommunale Kernkompetenzen, zur Nutzung privaten Know-hows sowie zu Kosteneinsparungen und Effizienzgewinnen. F{\"u}r die privaten Partner sind PPPs eine M{\"o}glichkeit zur Erschließung neuer M{\"a}rkte und Generierung lukrativer Auftr{\"a}ge. Gleichzeitig bringen die Planung, die Finanzierung, der Betrieb und die Beendigung {\"O}ffentlich Privater Partnerschaften jedoch komplexe rechtliche und praktische Probleme mit sich. Vor diesem Hintergrund widmete sich die 14. Jahrestagung des Kommunalwissenschaftlichen Institutes (KWI) der Universit{\"a}t Potsdam im April 2008 den rechtlichen Rahmenbedingungen und den praktischen Problemen im allt{\"a}glichen Umgang mit PPPs. Sie beleuchtete die verschiedenen Stationen des Lebenslaufs von PPPs und gab Antworten auf wichtige Fragestellungen bei der Implementierung und Umsetzung von PPP-Projekten. Behandelt wurden unter anderem Themen wie die Novellierung des Vertragsrechts im Verwaltungsverfahrensgesetz, Direktiven des Vergaberechts, M{\"o}glichkeiten der Finanzierung durch EU-F{\"o}rdermittel sowie institutionelle Alternativen (insbes. Public Public Partnerships) und L{\"o}sungswege beim Scheitern von PPPs.}, language = {de} }