@article{HuschbeckKnoopGahleitneretal.2020, author = {Huschbeck, Alina and Knoop, Michael and Gahleitner, Adrian and Koch, Stefan and Schrom, Thomas and Stoffel, Michael and Alfieri, Alex and Dengler, Julius}, title = {Recurrent laryngeal nerve palsy after anterior cervical discectomy and fusion}, series = {Journal of neurological surgery. Part A, Central European neurosurgery}, volume = {81}, journal = {Journal of neurological surgery. Part A, Central European neurosurgery}, number = {06}, publisher = {Thieme}, address = {New York}, issn = {2193-6315}, doi = {10.1055/s-0040-1710351}, pages = {508 -- 512}, year = {2020}, abstract = {Background and Study Aims Recurrent laryngeal nerve palsy (RLNP) is a potential complication of anterior discectomy and fusion (ACDF). There still is substantial disagreement on the actual prevalence of RLNP after ACDF as well as on risk factors for postoperative RLNP. The aim of this study was to describe the prevalence of postoperative RLNP in a cohort of consecutive cases of ACDF and to examine potential risk factors. Materials and Methods This retrospective study included patients who underwent ACDF between 2005 and 2019 at a single neurosurgical center. As part of clinical routine, RLNP was examined prior to and after surgery by independent otorhinolaryngologists using endoscopic laryngoscopy. As potential risk factors for postoperative RLNP, we examined patient's age, sex, body mass index, multilevel surgery, and the duration of surgery. Results 214 consecutive cases were included. The prevalence of preoperative RLNP was 1.4\% (3/214) and the prevalence of postoperative RLNP was 9\% (19/211). The number of operated levels was 1 in 73.5\% (155/211), 2 in 24.2\% (51/211), and 3 or more in 2.4\% (5/211) of cases. Of all cases, 4.7\% (10/211) were repeat surgeries. There was no difference in the prevalence of RLNP between the primary surgery group (9.0\%, 18/183) versus the repeat surgery group (10.0\%, 1/10;p = 0.91). Also, there was no difference in any characteristics between subjects with postoperative RLNP compared with those without postoperative RLNP. We found no association between postoperative RLNP and patient's age, sex, body mass index, duration of surgery, or number of levels (odds ratios between 0.24 and 1.05; p values between 0.20 and 0.97). Conclusions In our cohort, the prevalence of postoperative RLNP after ACDF was 9.0\%. The fact that none of the examined variables was associated with the occurrence of RLNP supports the view that postoperative RLNP may depend more on direct mechanical manipulation during surgery than on specific patient or surgical characteristics.}, language = {en} } @article{WeberAbuAyyashAbueladasetal.2009, author = {Weber, Michael H. and Abu-Ayyash, Khalil and Abueladas, Abdel-Rahman and Agnon, Amotz and Alasonati-Taš{\´a}rov{\´a}, Zuzana and Al-Zubi, Hashim and Babeyko, Andrey and Bartov, Yuval and Bauer, Klaus and Becken, Michael and Bedrosian, Paul A. and Ben-Avraham, Zvi and Bock, G{\"u}nter and Bohnhoff, Marco and Bribach, Jens and Dulski, Peter and Ebbing, Joerg and El-Kelani, Radwan J. and Foerster, Andrea and F{\"o}rster, Hans-J{\"u}rgen and Frieslander, Uri and Garfunkel, Zvi and G{\"o}tze, Hans-J{\"u}rgen and Haak, Volker and Haberland, Christian and Hassouneh, Mohammed and Helwig, Stefan L. and Hofstetter, Alfons and Hoffmann-Rothe, Arne and Jaeckel, Karl-Heinz and Janssen, Christoph and Jaser, Darweesh and Kesten, Dagmar and Khatib, Mohammed Ghiath and Kind, Rainer and Koch, Olaf and Koulakov, Ivan and Laske, Maria Gabi and Maercklin, Nils}, title = {Anatomy of the Dead Sea transform from lithospheric to microscopic scale}, issn = {8755-1209}, doi = {10.1029/2008rg000264}, year = {2009}, abstract = {Fault zones are the locations where motion of tectonic plates, often associated with earthquakes, is accommodated. Despite a rapid increase in the understanding of faults in the last decades, our knowledge of their geometry, petrophysical properties, and controlling processes remains incomplete. The central questions addressed here in our study of the Dead Sea Transform (DST) in the Middle East are as follows: (1) What are the structure and kinematics of a large fault zone? (2) What controls its structure and kinematics? (3) How does the DST compare to other plate boundary fault zones? The DST has accommodated a total of 105 km of left-lateral transform motion between the African and Arabian plates since early Miocene (similar to 20 Ma). The DST segment between the Dead Sea and the Red Sea, called the Arava/Araba Fault (AF), is studied here using a multidisciplinary and multiscale approach from the mu m to the plate tectonic scale. We observe that under the DST a narrow, subvertical zone cuts through crust and lithosphere. First, from west to east the crustal thickness increases smoothly from 26 to 39 km, and a subhorizontal lower crustal reflector is detected east of the AF. Second, several faults exist in the upper crust in a 40 km wide zone centered on the AF, but none have kilometer-size zones of decreased seismic velocities or zones of high electrical conductivities in the upper crust expected for large damage zones. Third, the AF is the main branch of the DST system, even though it has accommodated only a part (up to 60 km) of the overall 105 km of sinistral plate motion. Fourth, the AF acts as a barrier to fluids to a depth of 4 km, and the lithology changes abruptly across it. Fifth, in the top few hundred meters of the AF a locally transpressional regime is observed in a 100-300 m wide zone of deformed and displaced material, bordered by subparallel faults forming a positive flower structure. Other segments of the AF have a transtensional character with small pull-aparts along them. The damage zones of the individual faults are only 5-20 m wide at this depth range. Sixth, two areas on the AF show mesoscale to microscale faulting and veining in limestone sequences with faulting depths between 2 and 5 km. Seventh, fluids in the AF are carried downward into the fault zone. Only a minor fraction of fluids is derived from ascending hydrothermal fluids. However, we found that on the kilometer scale the AF does not act as an important fluid conduit. Most of these findings are corroborated using thermomechanical modeling where shear deformation in the upper crust is localized in one or two major faults; at larger depth, shear deformation occurs in a 20-40 km wide zone with a mechanically weak decoupling zone extending subvertically through the entire lithosphere.}, language = {en} } @article{StolterfohtCaprioglioWolffetal.2019, author = {Stolterfoht, Martin and Caprioglio, Pietro and Wolff, Christian Michael and Marquez, Jose A. and Nordmann, Joleik and Zhang, Shanshan and Rothhardt, Daniel and H{\"o}rmann, Ulrich and Amir, Yohai and Redinger, Alex and Kegelmann, Lukas and Zu, Fengshuo and Albrecht, Steve and Koch, Norbert and Kirchartz, Thomas and Saliba, Michael and Unold, Thomas and Neher, Dieter}, title = {The impact of energy alignment and interfacial recombination on the internal and external open-circuit voltage of perovskite solar cells}, series = {Energy \& environmental science}, volume = {12}, journal = {Energy \& environmental science}, number = {9}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1754-5692}, doi = {10.1039/c9ee02020a}, pages = {2778 -- 2788}, year = {2019}, abstract = {Charge transport layers (CTLs) are key components of diffusion controlled perovskite solar cells, however, they can induce additional non-radiative recombination pathways which limit the open circuit voltage (V-OC) of the cell. In order to realize the full thermodynamic potential of the perovskite absorber, both the electron and hole transport layer (ETL/HTL) need to be as selective as possible. By measuring the photoluminescence yield of perovskite/CTL heterojunctions, we quantify the non-radiative interfacial recombination currents in pin- and nip-type cells including high efficiency devices (21.4\%). Our study comprises a wide range of commonly used CTLs, including various hole-transporting polymers, spiro-OMeTAD, metal oxides and fullerenes. We find that all studied CTLs limit the V-OC by inducing an additional non-radiative recombination current that is in most cases substantially larger than the loss in the neat perovskite and that the least-selective interface sets the upper limit for the V-OC of the device. Importantly, the V-OC equals the internal quasi-Fermi level splitting (QFLS) in the absorber layer only in high efficiency cells, while in poor performing devices, the V-OC is substantially lower than the QFLS. Using ultraviolet photoelectron spectroscopy and differential charging capacitance experiments we show that this is due to an energy level mis-alignment at the p-interface. The findings are corroborated by rigorous device simulations which outline important considerations to maximize the V-OC. This work highlights that the challenge to suppress non-radiative recombination losses in perovskite cells on their way to the radiative limit lies in proper energy level alignment and in suppression of defect recombination at the interfaces.}, language = {en} } @article{GarbusowSchadSeboldetal.2016, author = {Garbusow, Maria and Schad, Daniel and Sebold, Miriam and Friedel, Eva and Bernhardt, Nadine and Koch, Stefan P. and Steinacher, Bruno and Kathmann, Norbert and Geurts, Dirk E. M. and Sommer, Christian and Mueller, Dirk K. and Nebe, Stephan and Paul, Soeren and Wittchen, Hans-Ulrich and Zimmermann, Ulrich S. and Walter, Henrik and Smolka, Michael N. and Sterzer, Philipp and Rapp, Michael A. and Huys, Quentin J. M. and Schlagenhauf, Florian and Heinz, Andreas}, title = {Pavlovian-to-instrumental transfer effects in the nucleus accumbens relate to relapse in alcohol dependence}, series = {Addiction biology}, volume = {21}, journal = {Addiction biology}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {1355-6215}, doi = {10.1111/adb.12243}, pages = {719 -- 731}, year = {2016}, abstract = {In detoxified alcohol-dependent patients, alcohol-related stimuli can promote relapse. However, to date, the mechanisms by which contextual stimuli promote relapse have not been elucidated in detail. One hypothesis is that such contextual stimuli directly stimulate the motivation to drink via associated brain regions like the ventral striatum and thus promote alcohol seeking, intake and relapse. Pavlovian-to-Instrumental-Transfer (PIT) may be one of those behavioral phenomena contributing to relapse, capturing how Pavlovian conditioned (contextual) cues determine instrumental behavior (e.g. alcohol seeking and intake). We used a PIT paradigm during functional magnetic resonance imaging to examine the effects of classically conditioned Pavlovian stimuli on instrumental choices in n=31 detoxified patients diagnosed with alcohol dependence and n=24 healthy controls matched for age and gender. Patients were followed up over a period of 3 months. We observed that (1) there was a significant behavioral PIT effect for all participants, which was significantly more pronounced in alcohol-dependent patients; (2) PIT was significantly associated with blood oxygen level-dependent (BOLD) signals in the nucleus accumbens (NAcc) in subsequent relapsers only; and (3) PIT-related NAcc activation was associated with, and predictive of, critical outcomes (amount of alcohol intake and relapse during a 3 months follow-up period) in alcohol-dependent patients. These observations show for the first time that PIT-related BOLD signals, as a measure of the influence of Pavlovian cues on instrumental behavior, predict alcohol intake and relapse in alcohol dependence.}, language = {en} } @article{KirchnerKoch2020, author = {Kirchner, Vera and Koch, Michael}, title = {Mehr als ein "bisschen" Haushalt - Haushalten als {\"o}konomisches Prinzip im Unterricht}, series = {Unterricht Wirtschaft + Politik}, journal = {Unterricht Wirtschaft + Politik}, number = {3}, editor = {Kirchner, Vera and Koch, Michael}, publisher = {Friedrich Verlag}, address = {Hannover}, issn = {2191-6624}, pages = {2 -- 7}, year = {2020}, language = {de} } @article{StarkeKochKammeretal.2018, author = {Starke, Ines and Koch, Andreas and Kammer, Stefan and Holdt, Hans-J{\"u}rgen and M{\"o}ller, Heiko Michael}, title = {Electrospray mass spectrometry and molecular modeling study of formation and stability of silver complexes with diazaperylene and bisisoquinoline}, series = {Journal of mass spectrometry}, volume = {53}, journal = {Journal of mass spectrometry}, number = {5}, publisher = {Wiley}, address = {Hoboken}, issn = {1076-5174}, doi = {10.1002/jms.4071}, pages = {408 -- 418}, year = {2018}, abstract = {The complex formation of the following diazaperylene ligands (L) 1,12-diazaperylene 1, 1,1-bisisoquinoline 2, 2,11-disubstituted 1,12-diazaperylenes (alkyl=methyl, ethyl, isopropyl, 3, 5, 7), 3,3-disubstituted 1,1-bisisoquinoline (alkyl=methyl, ethyl, isopropyl, 4, 6, 8 and with R=phenyl, 11 and with pyridine 12), and the 5,8-dimethoxy-substituted diazaperylene 9, 6,6-dimethoxy-substituted bisisoquinoline 10 with AgBF4 was investigated. Collision-induced dissociation measurements were used to evaluate the relative stabilities of the ligands themselves and for the [1:1](+) complexes as well as for the homoleptic and heteroleptic silver [1:2](+) complexes in the gas phase. This method is very useful in rapid screening of the stabilities of new complexes in the gas phase. The influence of the spatial arrangement of the ligands and the type of substituents employed for the complexation were examined. The effect of the preorganization of the diazaperylene on the threshold activation voltages and thus of the relative binding energies of the different complexes are discussed. Density functional theory calculations were used to calculate the optimized structures of the silver complexes and compared with the stabilities of the complexes in the gas phase for the first time.}, language = {en} } @article{WeberHelwigBaueretal.2012, author = {Weber, Michael H. and Helwig, S. L. and Bauer, Klaus and Haberland, Christian and Koch, Olaf and Ryberg, T. and Maercklin, N. and Ritter, O. and Schulze, A.}, title = {Near-surface properties of an active fault derived by joint interpretation of different geophysical methods - the Arava/Araba Fault in the Middle East}, series = {Near surface geophysics}, volume = {10}, journal = {Near surface geophysics}, number = {5}, publisher = {European Association of Geoscientists \& Engineers}, address = {Houten}, issn = {1569-4445}, doi = {10.3997/1873-0604.2012031}, pages = {381 -- 390}, year = {2012}, abstract = {The motion of tectonic plates is accommodated at fault zones. One of the unanswered questions about fault zones relates to the role they play in controlling shallow and local hydrology. This study focuses on the Arava/Araba Fault (AF) zone, the southern portion of the Dead Sea Transform (DST) in the Middle East. We combine seismic and electromagnetic methods (EM) to image the geometry and map the petro-physical properties and water occurrence in the top 100 m of this active fault. For three profiles, P-velocity and resistivity images were derived independently. Using a neural network cluster analysis three classes with similar P-velocity and resistivities could then be determined from these images. These classes correspond to spatial domains of specific material and wetness. The first class occurs primarily east of the fault consisting of 'wet' sand (dunes) and brecciated sediments, whereas the second class composed of similar material located west of the fault is 'dry'. The third class lies at depth below ca. 50 m and is composed of highly deformed and weathered Precambrian rocks that constitute the multi-branch fault zone of the AF at this location. The combination of two independent measurements like seismics and EM linked by a stringent mathematical approach has thus shown the potential to delineate the interplay of lithology and water near active faults.}, language = {en} } @article{KochTitzeSchroederetal.1999, author = {Koch, Sabine and Titze, Karl and Schr{\"o}der, Michael and Zimmermann, Ralf B. and Lehmkuhl, Gerd and Rauh, Hellgard}, title = {Longterm neurological consequences of maternal epilepsy and anticonvulsant treatment during pregnancy for school-age children and adolescents}, issn = {0013-9580}, year = {1999}, language = {en} } @article{AmbergausdemMooreBekketal.2022, author = {Amberg, Maximilian and aus dem Moore, Nils and Bekk, Anke and Bergmann, Tobias and Edenhofer, Ottmar and Flachsland, Christian and George, Jan and Haywood, Luke and Heinemann, Maik and Held, Anne and Kalkuhl, Matthias and Kellner, Maximilian and Koch, Nicolas and Luderer, Gunnar and Meyer, Henrika and Nikodinoska, Dragana and Pahle, Michael and Roolfs, Christina and Schill, Wolf-Peter}, title = {Reformoptionen f{\"u}r ein nachhaltiges Steuer- und Abgabensystem}, series = {Perspektiven der Wirtschaftspolitik}, volume = {23}, journal = {Perspektiven der Wirtschaftspolitik}, number = {3}, publisher = {De Gruyter}, address = {Berlin}, issn = {1465-6493}, doi = {10.1515/pwp-2021-0051}, pages = {165 -- 199}, year = {2022}, abstract = {Steuern und Abgaben auf Produkte oder Verbrauch mit gesellschaftlichen Folgekosten (externe Kosten) - sogenannte Pigou- oder Lenkungssteuern - sind ein gesellschaftliches „Win-Win-Instrument". Sie verbessern die Wohlfahrt und sch{\"u}tzen gleichzeitig die Umwelt und das Klima. Dies wird erreicht, indem umweltsch{\"a}digende Aktivit{\"a}ten einen Preis bekommen, der m{\"o}glichst exakt der H{\"o}he des Schadens entspricht. Eine konsequente Bepreisung der externen Kosten nach diesem Prinzip k{\"o}nnte in Deutschland erhebliche zus{\"a}tzliche Einnahmen erbringen: Basierend auf bisherigen Studien zu externen Kosten w{\"a}ren zus{\"a}tzliche Einnahmen in der Gr{\"o}ßenordnung von 348 bis 564 Milliarden Euro pro Jahr (44 bis 71 Prozent der gesamten Steuereinnahmen) m{\"o}glich. Die Autoren warnen allerdings, dass die Bezifferung der externen Kosten mit erheblichen Unsicherheiten verbunden ist. Damit Lenkungssteuern und -abgaben ihre positiven Lenkungs- und Wohlstandseffekte voll entfalten k{\"o}nnen, seien zudem institutionelle Reformen notwendig.}, language = {de} } @book{AkyaziBergmannDieterichsetal.2023, author = {Akyazi, Mehmet and Bergmann, Dana and Dieterichs, Michael and G{\"a}nz, Victoria and Hinz, Carsten and Huhn, Nicola and Klitsch, Constantin and Koch, Hayo and L{\"o}ffler, Robert and Meis, Robin and Penning, Isabelle and Rasky, Nicolai and Richter, Christin and Schellen, Ricarda and Schr{\"o}dter, Ayla and Schulz, Oliver and Simon, Veronika and Trojecka, Anetta and Verwohlt, Peter and Vogler, Christin and Vogt, Birgit}, title = {\#Gesellschaftslehre 9/10}, volume = {[Sch{\"u}lerband]}, publisher = {C.C. Buchner}, address = {Bamberg}, isbn = {978-3-661-70053-3}, pages = {464}, year = {2023}, language = {de} }