@article{TaalStPourcainThieringetal.2012, author = {Taal, H. Rob and St Pourcain, Beate and Thiering, Elisabeth and Das, Shikta and Mook-Kanamori, Dennis O. and Warrington, Nicole M. and Kaakinen, Marika and Kreiner-Moller, Eskil and Bradfield, Jonathan P. and Freathy, Rachel M. and Geller, Frank and Guxens, Monica and Cousminer, Diana L. and Kerkhof, Marjan and Timpson, Nicholas J. and Ikram, M. Arfan and Beilin, Lawrence J. and Bonnelykke, Klaus and Buxton, Jessica L. and Charoen, Pimphen and Chawes, Bo Lund Krogsgaard and Eriksson, Johan and Evans, David M. and Hofman, Albert and Kemp, John P. and Kim, Cecilia E. and Klopp, Norman and Lahti, Jari and Lye, Stephen J. and McMahon, George and Mentch, Frank D. and Mueller-Nurasyid, Martina and O'Reilly, Paul F. and Prokopenko, Inga and Rivadeneira, Fernando and Steegers, Eric A. P. and Sunyer, Jordi and Tiesler, Carla and Yaghootkar, Hanieh and Breteler, Monique M. B. and Debette, Stephanie and Fornage, Myriam and Gudnason, Vilmundur and Launer, Lenore J. and van der Lugt, Aad and Mosley, Thomas H. and Seshadri, Sudha and Smith, Albert V. and Vernooij, Meike W. and Blakemore, Alexandra I. F. and Chiavacci, Rosetta M. and Feenstra, Bjarke and Fernandez-Banet, Julio and Grant, Struan F. A. and Hartikainen, Anna-Liisa and van der Heijden, Albert J. and Iniguez, Carmen and Lathrop, Mark and McArdle, Wendy L. and Molgaard, Anne and Newnham, John P. and Palmer, Lyle J. and Palotie, Aarno and Pouta, Annneli and Ring, Susan M. and Sovio, Ulla and Standl, Marie and Uitterlinden, Andre G. and Wichmann, H-Erich and Vissing, Nadja Hawwa and DeCarli, Charles and van Duijn, Cornelia M. and McCarthy, Mark I. and Koppelman, Gerard H. and Estivill, Xavier and Hattersley, Andrew T. and Melbye, Mads and Bisgaard, Hans and Pennell, Craig E. and Widen, Elisabeth and Hakonarson, Hakon and Smith, George Davey and Heinrich, Joachim and Jarvelin, Marjo-Riitta and Jaddoe, Vincent W. V. and Adair, Linda S. and Ang, Wei and Atalay, Mustafa and van Beijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Bradfield, Jonathan P. and Charoen, Pimphen and Coin, Lachlan and Cousminer, Diana L. and Das, Shikta and Davis, Oliver S. P. and Elliott, Paul and Evans, David M. and Feenstra, Bjarke and Flexeder, Claudia and Frayling, Tim and Freathy, Rachel M. and Gaillard, Romy and Geller, Frank and Groen-Blokhuis, Maria and Goh, Liang-Kee and Guxens, Monica and Haworth, Claire M. A. and Hadley, Dexter and Hebebrand, Johannes and Hinney, Anke and Hirschhorn, Joel N. and Holloway, John W. and Holst, Claus and Hottenga, Jouke Jan and Horikoshi, Momoko and Huikari, Ville and Hypponen, Elina and Iniguez, Carmen and Kaakinen, Marika and Kilpelainen, Tuomas O. and Kirin, Mirna and Kowgier, Matthew and Lakka, Hanna-Maaria and Lange, Leslie A. and Lawlor, Debbie A. and Lehtimaki, Terho and Lewin, Alex and Lindgren, Cecilia and Lindi, Virpi and Maggi, Reedik and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Mook-Kanamori, Dennis O. and Murray, Jeffrey C. and Nivard, Michel and Nohr, Ellen Aagaard and Ntalla, Ioanna and Oken, Emily and O'Reilly, Paul F. and Palmer, Lyle J. and Panoutsopoulou, Kalliope and Pararajasingham, Jennifer and Prokopenko, Inga and Rodriguez, Alina and Salem, Rany M. and Sebert, Sylvain and Siitonen, Niina and Sovio, Ulla and St Pourcain, Beate and Strachan, David P. and Sunyer, Jordi and Taal, H. Rob and Teo, Yik-Ying and Thiering, Elisabeth and Tiesler, Carla and Uitterlinden, Andre G. and Valcarcel, Beatriz and Warrington, Nicole M. and White, Scott and Willemsen, Gonneke and Yaghootkar, Hanieh and Zeggini, Eleftheria and Boomsma, Dorret I. and Cooper, Cyrus and Estivill, Xavier and Gillman, Matthew and Grant, Struan F. A. and Hakonarson, Hakon and Hattersley, Andrew T. and Heinrich, Joachim and Hocher, Berthold and Jaddoe, Vincent W. V. and Jarvelin, Marjo-Riitta and Lakka, Timo A. and McCarthy, Mark I. and Melbye, Mads and Mohlke, Karen L. and Dedoussis, George V. and Ong, Ken K. and Pearson, Ewan R. and Pennell, Craig E. and Price, Thomas S. and Power, Chris and Raitakari, Olli T. and Saw, Seang-Mei and Scherag, Andre and Simell, Olli and Sorensen, Thorkild I. A. and Timpson, Nicholas J. and Widen, Elisabeth and Wilson, James F. and Ang, Wei and van Beijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Bradfield, Jonathan P. and Charoen, Pimphen and Coin, Lachlan and Cousminer, Diana L. and Das, Shikta and Elliott, Paul and Evans, David M. and Frayling, Tim and Freathy, Rachel M. and Gaillard, Romy and Groen-Blokhuis, Maria and Guxens, Monica and Hadley, Dexter and Hottenga, Jouke Jan and Huikari, Ville and Hypponen, Elina and Kaakinen, Marika and Kowgier, Matthew and Lawlor, Debbie A. and Lewin, Alex and Lindgren, Cecilia and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Mook-Kanamori, Dennis O. and Nivard, Michel and O'Reilly, Paul F. and Palmer, Lyle J. and Prokopenko, Inga and Rodriguez, Alina and Sebert, Sylvain and Sovio, Ulla and St Pourcain, Beate and Standl, Marie and Strachan, David P. and Sunyer, Jordi and Taal, H. Rob and Thiering, Elisabeth and Tiesler, Carla and Uitterlinden, Andre G. and Valcarcel, Beatriz and Warrington, Nicole M. and White, Scott and Willemsen, Gonneke and Yaghootkar, Hanieh and Boomsma, Dorret I. and Estivill, Xavier and Grant, Struan F. A. and Hakonarson, Hakon and Hattersley, Andrew T. and Heinrich, Joachim and Jaddoe, Vincent W. V. and Jarvelin, Marjo-Riitta and McCarthy, Mark I. and Pennell, Craig E. and Power, Chris and Timpson, Nicholas J. and Widen, Elisabeth and Ikram, M. Arfan and Fornage, Myriam and Smith, Albert V. and Seshadri, Sudha and Schmidt, Reinhold and Debette, Stephanie and Vrooman, Henri A. and Sigurdsson, Sigurdur and Ropele, Stefan and Coker, Laura H. and Longstreth, W. T. and Niessen, Wiro J. and DeStefano, Anita L. and Beiser, Alexa and Zijdenbos, Alex P. and Struchalin, Maksim and Jack, Clifford R. and Nalls, Mike A. and Au, Rhoda and Hofman, Albert and Gudnason, Haukur and van der Lugt, Aad and Harris, Tamara B. and Meeks, William M. and Vernooij, Meike W. and van Buchem, Mark A. and Catellier, Diane and Gudnason, Vilmundur and Windham, B. Gwen and Wolf, Philip A. and van Duijn, Cornelia M. and Mosley, Thomas H. and Schmidt, Helena and Launer, Lenore J. and Breteler, Monique M. B. and DeCarli, Charles}, title = {Common variants at 12q15 and 12q24 are associated with infant head circumference}, series = {Nature genetics}, volume = {44}, journal = {Nature genetics}, number = {5}, publisher = {Nature Publ. Group}, address = {New York}, organization = {Cohorts Heart Aging Res Genetic Ep, Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti}, issn = {1061-4036}, doi = {10.1038/ng.2238}, pages = {532 -- +}, year = {2012}, abstract = {To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.}, language = {en} } @article{AartsAndersonAndersonetal.2015, author = {Aarts, Alexander A. and Anderson, Joanna E. and Anderson, Christopher J. and Attridge, Peter R. and Attwood, Angela and Axt, Jordan and Babel, Molly and Bahnik, Stepan and Baranski, Erica and Barnett-Cowan, Michael and Bartmess, Elizabeth and Beer, Jennifer and Bell, Raoul and Bentley, Heather and Beyan, Leah and Binion, Grace and Borsboom, Denny and Bosch, Annick and Bosco, Frank A. and Bowman, Sara D. and Brandt, Mark J. and Braswell, Erin and Brohmer, Hilmar and Brown, Benjamin T. and Brown, Kristina and Bruening, Jovita and Calhoun-Sauls, Ann and Callahan, Shannon P. and Chagnon, Elizabeth and Chandler, Jesse and Chartier, Christopher R. and Cheung, Felix and Christopherson, Cody D. and Cillessen, Linda and Clay, Russ and Cleary, Hayley and Cloud, Mark D. and Cohn, Michael and Cohoon, Johanna and Columbus, Simon and Cordes, Andreas and Costantini, Giulio and Alvarez, Leslie D. Cramblet and Cremata, Ed and Crusius, Jan and DeCoster, Jamie and DeGaetano, Michelle A. and Della Penna, Nicolas and den Bezemer, Bobby and Deserno, Marie K. and Devitt, Olivia and Dewitte, Laura and Dobolyi, David G. and Dodson, Geneva T. and Donnellan, M. Brent and Donohue, Ryan and Dore, Rebecca A. and Dorrough, Angela and Dreber, Anna and Dugas, Michelle and Dunn, Elizabeth W. and Easey, Kayleigh and Eboigbe, Sylvia and Eggleston, Casey and Embley, Jo and Epskamp, Sacha and Errington, Timothy M. and Estel, Vivien and Farach, Frank J. and Feather, Jenelle and Fedor, Anna and Fernandez-Castilla, Belen and Fiedler, Susann and Field, James G. and Fitneva, Stanka A. and Flagan, Taru and Forest, Amanda L. and Forsell, Eskil and Foster, Joshua D. and Frank, Michael C. and Frazier, Rebecca S. and Fuchs, Heather and Gable, Philip and Galak, Jeff and Galliani, Elisa Maria and Gampa, Anup and Garcia, Sara and Gazarian, Douglas and Gilbert, Elizabeth and Giner-Sorolla, Roger and Gl{\"o}ckner, Andreas and G{\"o}llner, Lars and Goh, Jin X. and Goldberg, Rebecca and Goodbourn, Patrick T. and Gordon-McKeon, Shauna and Gorges, Bryan and Gorges, Jessie and Goss, Justin and Graham, Jesse and Grange, James A. and Gray, Jeremy and Hartgerink, Chris and Hartshorne, Joshua and Hasselman, Fred and Hayes, Timothy and Heikensten, Emma and Henninger, Felix and Hodsoll, John and Holubar, Taylor and Hoogendoorn, Gea and Humphries, Denise J. and Hung, Cathy O. -Y. and Immelman, Nathali and Irsik, Vanessa C. and Jahn, Georg and Jaekel, Frank and Jekel, Marc and Johannesson, Magnus and Johnson, Larissa G. and Johnson, David J. and Johnson, Kate M. and Johnston, William J. and Jonas, Kai and Joy-Gaba, Jennifer A. and Kappes, Heather Barry and Kelso, Kim and Kidwell, Mallory C. and Kim, Seung Kyung and Kirkhart, Matthew and Kleinberg, Bennett and Knezevic, Goran and Kolorz, Franziska Maria and Kossakowski, Jolanda J. and Krause, Robert Wilhelm and Krijnen, Job and Kuhlmann, Tim and Kunkels, Yoram K. and Kyc, Megan M. and Lai, Calvin K. and Laique, Aamir and Lakens, Daniel and Lane, Kristin A. and Lassetter, Bethany and Lazarevic, Ljiljana B. and LeBel, Etienne P. and Lee, Key Jung and Lee, Minha and Lemm, Kristi and Levitan, Carmel A. and Lewis, Melissa and Lin, Lin and Lin, Stephanie and Lippold, Matthias and Loureiro, Darren and Luteijn, Ilse and Mackinnon, Sean and Mainard, Heather N. and Marigold, Denise C. and Martin, Daniel P. and Martinez, Tylar and Masicampo, E. J. and Matacotta, Josh and Mathur, Maya and May, Michael and Mechin, Nicole and Mehta, Pranjal and Meixner, Johannes and Melinger, Alissa and Miller, Jeremy K. and Miller, Mallorie and Moore, Katherine and M{\"o}schl, Marcus and Motyl, Matt and M{\"u}ller, Stephanie M. and Munafo, Marcus and Neijenhuijs, Koen I. and Nervi, Taylor and Nicolas, Gandalf and Nilsonne, Gustav and Nosek, Brian A. and Nuijten, Michele B. and Olsson, Catherine and Osborne, Colleen and Ostkamp, Lutz and Pavel, Misha and Penton-Voak, Ian S. and Perna, Olivia and Pernet, Cyril and Perugini, Marco and Pipitone, R. Nathan and Pitts, Michael and Plessow, Franziska and Prenoveau, Jason M. and Rahal, Rima-Maria and Ratliff, Kate A. and Reinhard, David and Renkewitz, Frank and Ricker, Ashley A. and Rigney, Anastasia and Rivers, Andrew M. and Roebke, Mark and Rutchick, Abraham M. and Ryan, Robert S. and Sahin, Onur and Saide, Anondah and Sandstrom, Gillian M. and Santos, David and Saxe, Rebecca and Schlegelmilch, Rene and Schmidt, Kathleen and Scholz, Sabine and Seibel, Larissa and Selterman, Dylan Faulkner and Shaki, Samuel and Simpson, William B. and Sinclair, H. Colleen and Skorinko, Jeanine L. M. and Slowik, Agnieszka and Snyder, Joel S. and Soderberg, Courtney and Sonnleitner, Carina and Spencer, Nick and Spies, Jeffrey R. and Steegen, Sara and Stieger, Stefan and Strohminger, Nina and Sullivan, Gavin B. and Talhelm, Thomas and Tapia, Megan and te Dorsthorst, Anniek and Thomae, Manuela and Thomas, Sarah L. and Tio, Pia and Traets, Frits and Tsang, Steve and Tuerlinckx, Francis and Turchan, Paul and Valasek, Milan and Van Aert, Robbie and van Assen, Marcel and van Bork, Riet and van de Ven, Mathijs and van den Bergh, Don and van der Hulst, Marije and van Dooren, Roel and van Doorn, Johnny and van Renswoude, Daan R. and van Rijn, Hedderik and Vanpaemel, Wolf and Echeverria, Alejandro Vasquez and Vazquez, Melissa and Velez, Natalia and Vermue, Marieke and Verschoor, Mark and Vianello, Michelangelo and Voracek, Martin and Vuu, Gina and Wagenmakers, Eric-Jan and Weerdmeester, Joanneke and Welsh, Ashlee and Westgate, Erin C. and Wissink, Joeri and Wood, Michael and Woods, Andy and Wright, Emily and Wu, Sining and Zeelenberg, Marcel and Zuni, Kellylynn}, title = {Estimating the reproducibility of psychological science}, series = {Science}, volume = {349}, journal = {Science}, number = {6251}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, organization = {Open Sci Collaboration}, issn = {1095-9203}, doi = {10.1126/science.aac4716}, pages = {8}, year = {2015}, abstract = {Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47\% of original effect sizes were in the 95\% confidence interval of the replication effect size; 39\% of effects were subjectively rated to have replicated the original result; and if no bias in original results is assumed, combining original and replication results left 68\% with statistically significant effects. Correlational tests suggest that replication success was better predicted by the strength of original evidence than by characteristics of the original and replication teams.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chatraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, Markus and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, O. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. P. and Lohse, T. and Lopatin, A. and Lu, C-C and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, Markus and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Anibas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P-O and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J-P and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H-S}, title = {HESS detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {574}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {0004-6361}, doi = {10.1051/0004-6361/201425070}, pages = {7}, year = {2015}, abstract = {G349.7+0.2 is a young Galactic supernova remnant (SNR) located at the distance of 11.5 kpc and observed across the entire electromagnetic spectrum from radio to high energy (HE; 0.1 GeV < E < 100 GeV) gamma-rays. Radio and infrared observations indicate that the remnant is interacting with a molecular cloud. In this paper, the detection of very high energy (VHE, E > 100 GeV) gamma-ray emission coincident with this SNR with the High Energy Stereoscopic System (HESS.) is reported. This makes it one of the farthest Galactic SNR ever detected in this domain. An integral flux F(E > 400 GeV) = (6.5 +/- 1.1(stat) +/- 1.3(syst)) x 10-11 ph cm(-2) s(-1) corresponding to similar to 0.7\% of that of the Crab Nebula and to a luminosity of similar to 10(34) erg s(-1) above the same energy threshold, and a steep photon index Gamma(VHE) = 2.8 +/- 0.27(stat) +/- 0.20(syst) are measured. The analysis of more than 5 yr of Fermi-LAT data towards this source shows a power-law like spectrum with a best-fit photon index Gamma(HE) = 2.2 +/- 0.04.2(stat-0.31sys)(+0.13), The combined gamma-ray spectrum of 0349.7+0.2 can be described by either a broken power law (I3PL) or a power law with exponential (or sub exponential) cutoff (PLC). In the former case, the photon break energy is found at E-br,E-gamma = 551(-30)(+70) GeV, slightly higher than what is usually observed in the HE/VHE gamma-ray emitting middle-aged SNRs known to be interacting with molecular clouds. In the latter case. the exponential (respectively sub-exponential) cutoff energy is measured at E-cat,E-gamma = 1.4(-0.55)(+1.6) (respectively 0.35(-0.21)(+0.75)) TeV. A pion decay process resulting from the interaction of the accelerated protons and nuclei with the dense surrounding medium is clearly the preferred scenario to explain the gamma-ray emission. The BPL with a spectral steepening of 0.5-1 and the PLC provide equally good fits to the data. The product or the average gas density and the total energy content of accelerated protons and nuclei amounts to nu W-p similar to 5 x 10(51) erg cm(-3)}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Becker-Tjus, J. and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Dalton, M. and Davids, I. D. and Degrange, B. and Deil, C. and de Wilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M-H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J-P. and Lohse, T. and Lopatin, A. and Lu, C-C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perez, J. and Petrucci, P-O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Rob, L. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J-P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H-S.}, title = {The exceptionally powerful TeV gamma-ray emitters in the Large Magellanic Cloud}, series = {Science}, volume = {347}, journal = {Science}, number = {6220}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, organization = {HESS Collaboration}, issn = {0036-8075}, doi = {10.1126/science.1261313}, pages = {406 -- 412}, year = {2015}, abstract = {The Large Magellanic Cloud, a satellite galaxy of the Milky Way, has been observed with the High Energy Stereoscopic System (H.E.S.S.) above an energy of 100 billion electron volts for a deep exposure of 210 hours. Three sources of different types were detected: the pulsar wind nebula of the most energetic pulsar known, N 157B; the radio-loud supernova remnant N 132D; and the largest nonthermal x-ray shell, the superbubble 30 Dor C. The unique object SN 1987A is, unexpectedly, not detected, which constrains the theoretical framework of particle acceleration in very young supernova remnants. These detections reveal the most energetic tip of a g-ray source population in an external galaxy and provide via 30 Dor C the unambiguous detection of g-ray emission from a superbubble.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2016, author = {Abdalla, Hassan E. and Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Andersson, T. and Ang{\"u}ner, Ekrem Oǧuzhan and Arrieta, M. and Aubert, Pierre and Backes, Michael and Balzer, Arnim and Barnard, Michelle and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Blackwell, R. and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Capasso, M. and Carr, John and Casanova, Sabrina and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chen, Andrew and Chevalier, J. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Condon, B. and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and Devin, J. and de Wilt, P. and Djannati-Ataie, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Hahn, J. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kerszberg, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Liu, R. and Lohse, T. and Lorentz, M. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, Michael and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oettl, S. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reimer, A. and Reimer, O. and Renaud, M. and Reyes, R. de los and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tluczykont, M. and Trichard, C. and Tuffs, R. and van der Walt, J. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {HESS Limits on Linelike Dark Matter Signatures in the 100 GeV to 2 TeV Energy Range Close to the Galactic Center}, series = {Physical review letters}, volume = {117}, journal = {Physical review letters}, publisher = {American Physical Society}, address = {College Park}, organization = {HESS Collaboration}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.117.151302}, pages = {7}, year = {2016}, abstract = {A search for dark matter linelike signals iss performed in the vicinity of the Galactic Center by the H.E.S.S. experiment on observational data taken in 2014. An unbinned likelihood analysis iss developed to improve the sensitivity to linelike signals. The upgraded analysis along with newer data extend the energy coverage of the previous measurement down to 100 GeV. The 18 h of data collected with the H.E.S.S. array allow one to rule out at 95\% C.L. the presence of a 130 GeV line (at l = -1.5 degrees, b = 0 degrees and for a dark matter profile centered at this location) previously reported in Fermi-LAT data. This new analysis overlaps significantly in energy with previous Fermi-LAT and H.E.S.S. results. No significant excess associated with dark matter annihilations was found in the energy range of 100 GeV to 2 TeV and upper limits on the gamma-ray flux and the velocity weighted annihilation cross section are derived adopting an Einasto dark matter halo profile. Expected limits for present and future large statistics H.E.S.S. observations are also given.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2014, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and B{\"o}ttcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Dalton, M. and Davids, I. D. and Degrange, B. and Deil, C. and dewilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Forster, A. and Fuling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadsch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, Markus and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kiefeer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Kruger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perez, J. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puhlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Rob, L. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and Van Eldik, C. and Van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Volk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Wornlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S.}, title = {Long-term monitoring of PKS2155-304 with ATOM and HESS:investigation of optical/gamma-ray correlations in different spectral states}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {571}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESSS Collaboration}, issn = {0004-6361}, doi = {10.1051/0004-6361/201424142}, pages = {10}, year = {2014}, abstract = {In this paper we report on the analysis of all the available optical and very high-energy gamma-ray (> 200 GeV) data for the BL Lac object PKS 2155-304, collected simultaneously with the ATOM and H.E.S.S. telescopes from 2007 until 2009. This study also includes X-ray (RXTE, Swift) and high-energy gamma-ray (Fermi-LAT) data. During the period analysed, the source was transitioning from its flaring to quiescent optical states, and was characterized by only moderate flux changes at different wavelengths on the timescales of days and months. A flattening of the optical continuum with an increasing optical flux can be noted in the collected dataset, but only occasionally and only at higher flux levels. We did not find any universal relation between the very high-energy gamma-ray and optical flux changes on the timescales from days and weeks up to several years. On the other hand, we noted that at higher flux levels the source can follow two distinct tracks in the optical flux-colour diagrams, which seem to be related to distinct gamma-ray states of the blazar. The obtained results therefore indicate a complex scaling between the optical and gamma-ray emission of PKS 2155 304, with different correlation patterns holding at different epochs, and a gamma-ray flux depending on the combination of an optical flux and colour rather than a flux alone.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, Margitte and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, Michael and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S.}, title = {Constraints on an Annihilation Signal from a Core of Constant Dark Matter Density around the Milky Way Center with HESS}, series = {Physical review letters}, volume = {114}, journal = {Physical review letters}, number = {8}, publisher = {American Physical Society}, address = {College Park}, organization = {HESS Collaboration}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.114.081301}, pages = {6}, year = {2015}, abstract = {An annihilation signal of dark matter is searched for from the central region of the Milky Way. Data acquired in dedicated on-off observations of the Galactic center region with H.E.S.S. are analyzed for this purpose. No significant signal is found in a total of similar to 9 h of on-off observations. Upper limits on the velocity averaged cross section, , for the annihilation of dark matter particles with masses in the range of similar to 300 GeV to similar to 10 TeV are derived. In contrast to previous constraints derived from observations of the Galactic center region, the constraints that are derived here apply also under the assumption of a central core of constant dark matter density around the center of the Galaxy. Values of that are larger than 3 x 10(-24) cm(3)/s are excluded for dark matter particles with masses between similar to 1 and similar to 4 TeV at 95\% C.L. if the radius of the central dark matter density core does not exceed 500 pc. This is the strongest constraint that is derived on for annihilating TeV mass dark matter without the assumption of a centrally cusped dark matter density distribution in the search region.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2014, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Dalton, M. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goudelis, A. and Grondin, M. -H. and Grudzinska, M. and Hadsch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perez, J. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, Olaf and Renaud, M. and de los Reyes, R. and Rieger, F. and Rob, L. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, Fabian and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Serpico, P. and Sol, H. and Spanier, F. and Spengler, G. and Spiess, F. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S.}, title = {Search for dark matter annihilation signatures in HESS observations of dwarf spheroidal galaxies}, series = {Physical review : D, Particles, fields, gravitation, and cosmology}, volume = {90}, journal = {Physical review : D, Particles, fields, gravitation, and cosmology}, number = {11}, publisher = {American Physical Society}, address = {College Park}, organization = {HESS Collaboration}, issn = {1550-7998}, doi = {10.1103/PhysRevD.90.112012}, pages = {15}, year = {2014}, abstract = {Dwarf spheroidal galaxies of the Local Group are close satellites of the Milky Way characterized by a large mass-to-light ratio and are not expected to be the site of nonthermal high-energy gamma-ray emission or intense star formation. Therefore they are among the most promising candidates for indirect dark matter searches. During the last years the High Energy Stereoscopic System (H.E.S.S.) of imaging atmospheric Cherenkov telescopes observed five of these dwarf galaxies for more than 140 hours in total, searching for TeV gamma-ray emission from annihilation of dark matter particles. The new results of the deep exposure of the Sagittarius dwarf spheroidal galaxy, the first observations of the Coma Berenices and Fornax dwarves and the reanalysis of two more dwarf spheroidal galaxies already published by the H.E.S.S. Collaboration, Carina and Sculptor, are presented. In the absence of a significant signal new constraints on the annihilation cross section applicable to weakly interacting massive particles (WIMPs) are derived by combining the observations of the five dwarf galaxies. The combined exclusion limit depends on the WIMP mass and the best constraint is reached at 1-2 TeV masses with a cross-section upper bound of similar to 3.9 x 10(-24) cm(3) s(-1) at a 95\% confidence level.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2016, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balzer, Arnim and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Blackwell, R. and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carr, John and Casanova, Sabrina and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chen, Andrew and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J-P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M-H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kerszberg, D. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J-P. and Lohse, T. and Lopatin, A. and Lu, C-C. and Lui, R. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Oakes, L. and Odaka, H. and Oettl, S. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P-O. and Peyaud, B. and Pita, S. and Poon, H. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seyffert, A. S. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J-P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Tuffs, R. and Valerius, K. and van der Walt, J. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Zywucka, N.}, title = {Acceleration of petaelectronvolt protons in the Galactic Centre}, series = {Nature : the international weekly journal of science}, volume = {531}, journal = {Nature : the international weekly journal of science}, publisher = {Nature Publ. Group}, address = {London}, organization = {HESS Collaboration}, issn = {0028-0836}, doi = {10.1038/nature17147}, pages = {476 -- +}, year = {2016}, abstract = {Galactic cosmic rays reach energies of at least a few petaelectronvolts (of the order of 1015 electronvolts). This implies that our Galaxy contains petaelectronvolt accelerators ('PeVatrons'), but all proposed models of Galactic cosmic-ray accelerators encounter difficulties at exactly these energies. Dozens of Galactic accelerators capable of accelerating particles to energies of tens of teraelectronvolts (of the order of 1013 electronvolts) were inferred from recent \&\#947;-ray observations3. However, none of the currently known accelerators—not even the handful of shell-type supernova remnants commonly believed to supply most Galactic cosmic rays—has shown the characteristic tracers of petaelectronvolt particles, namely, power-law spectra of \&\#947;-rays extending without a cut-off or a spectral break to tens of teraelectronvolts4. Here we report deep \&\#947;-ray observations with arcminute angular resolution of the region surrounding the Galactic Centre, which show the expected tracer of the presence of petaelectronvolt protons within the central 10 parsecs of the Galaxy. We propose that the supermassive black hole Sagittarius A* is linked to this PeVatron. Sagittarius A* went through active phases in the past, as demonstrated by X-ray outbursts5and an outflow from the Galactic Centre6. Although its current rate of particle acceleration is not sufficient to provide a substantial contribution to Galactic cosmic rays, Sagittarius A* could have plausibly been more active over the last 106-107 years, and therefore should be considered as a viable alternative to supernova remnants as a source of petaelectronvolt Galactic cosmic rays.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balzer, Arnim and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Blackwell, R. and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carr, John and Casanova, Sabrina and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chen, Andrew and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandesl, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieckl, M. A. and Katarzynski, K. and Katz, U. and Kerszberg, D. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Lui, R. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Oakes, L. and Odaka, H. and Oettl, S. and Ohm, S. and de Ona Wilhelmi, E. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seyffert, A. S. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van der Walt, J. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Zywucka, N.}, title = {Discovery of variable VHE gamma-ray emission from the binary system 1FGL J1018.6-5856}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {577}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {0004-6361}, doi = {10.1051/0004-6361/201525699}, pages = {6}, year = {2015}, abstract = {Re-observations with the HESS telescope array of the very high-energy (VHE) source HESS J1018-589A that is coincident with the Fermi-LAT gamma-ray binary 1FGL J1018.6-5856 have resulted in a source detection significance of more than 9 sigma and the detection of variability (chi(2)/nu of 238.3/155) in the emitted gamma-ray flux. This variability confirms the association of HESS J1018-589A with the high-energy gamma-ray binary detected Fermi-LAT and also confirms the point-like source as a new VHE binary system. The spectrum of HESS J1018-589A is best fit with a power-law function with photon index Gamma = 2.20 +/- 0.14(stat) +/- 0.2(sys). Emission is detected up to similar to 20 TeV. The mean differential flux level is (2.9 +/- 0.4) x 10(-13) TeV-1 cm(-2) s(-1) at 1 TeV, equivalent to similar to 1\% of the flux from the Crab Nebula at the same energy. Variability is clearly detected the night-by-night light curve. When folded on the orbital period of 16.58 days, the rebinned light curve peaks in phase with the observed X-ray high-energy phaseograms. The fit of the HESS phaseogram to a constant flux provides evidence of periodicity at the level of N-sigma > 3 sigma. The of the VHE phaseogram and measured spectrum suggest a low-inclination, low-eccentricity system with a modest impact from VHE gamma-ray due to pair production (tau less than or similar to 1 at 300 GeV).}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2014, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Uner, E. O. Ang and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Dalton, M. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, Markus and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and Reyes, R. de Los and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and Van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S. and Fukui, Y. and Sano, H. and Fukuda, T. and Yoshiike, S.}, title = {Discovery of the hard spectrum VHE gamma-ray source Hess J1641-463}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {794}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {HESS Collaboration}, issn = {2041-8205}, doi = {10.1088/2041-8205/794/1/L1}, pages = {6}, year = {2014}, abstract = {This Letter reports the discovery of a remarkably hard spectrum source, HESS J1641-463, by the High Energy Stereoscopic System (H.E.S.S.) in the very high energy (VHE) domain. HESS J1641-463 remained unnoticed by the usual analysis techniques due to confusion with the bright nearby source HESS J1640-465. It emerged at a significance level of 8.5 standard deviations after restricting the analysis to events with energies above 4 TeV. It shows a moderate flux level of phi(E > 1TeV) = (3.64 +/- 0.44(stat)+/- 0.73(sys)) x 10(-13) cm(-2) s(-1), corresponding to 1.8\% of the Crab Nebula flux above the same energy, and a hard spectrum with a photon index of Gamma = 2.07 +/- 0.11(stat)+/- 0.20(sys). It is a point-like source, although an extension up to a Gaussian width of sigma = 3 arcmin cannot be discounted due to uncertainties in the H.E.S.S. point-spread function. The VHE gamma-ray flux of HESS J1641-463 is found to be constant over the observed period when checking time binnings from the year-by-year to the 28 minute exposure timescales. HESS J1641-463 is positionally coincident with the radio supernova remnant SNR G338.5+0.1. No X-ray candidate stands out as a clear association; however, Chandra and XMM-Newton data reveal some potential weak counterparts. Various VHE gamma-ray production scenarios are discussed. If the emission from HESS J1641-463 is produced by cosmic ray protons colliding with the ambient gas, then their spectrum must extend close to 1 PeV. This object may represent a source population contributing significantly to the galactic cosmic ray flux around the knee.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and F{\"u}ssling, Matthias and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, Maraike and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, Michael and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S.}, title = {HESS reveals a lack of TeV emission from the supernova remnant Puppis A (Research Note)}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {575}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {0004-6361}, doi = {10.1051/0004-6361/2014424805}, pages = {6}, year = {2015}, abstract = {Context. Puppis A is an interesting similar to 4 kyr-old supernova remnant (SNR) that shows strong evidence of interaction between the forward shock and a molecular cloud. It has been studied in detail from radio frequencies to high-energy (HE, 0.1-100 GeV) gamma-rays. An analysis of the Fermi-LAT data has shown extended HE gamma-ray emission with a 0.2-100 GeV spectrum exhibiting no significant deviation from a power law, unlike most of the GeV-emitting SNRs known to be interacting with molecular clouds. This makes it a promising target for imaging atmospheric Cherenkov telescopes (IACTs) to probe the gamma-ray emission above 100 GeV. Aims. Very-high-energy (VHE, E >= 0.1 TeV) gamma-ray emission from Puppis A has been, for the first time, searched for with the High Energy Stereoscopic System (HESS.). Methods. Stereoscopic imaging of Cherenkov radiation from extensive air showers is used to reconstruct the direction and energy of the incident gamma-rays in order to produce sky images and source spectra. The profile likelihood method is applied to find constraints on the existence of a potential break or cutoff in the photon spectrum. Results. The analysis of the HESS. data does not reveal any significant emission towards Puppis A. The derived upper limits on the differential photon flux imply that its broadband gamma-ray spectrum must exhibit a spectral break or cutoff. By combining Fermi-LAT and HESS. measurements, the 99\% confidence-level upper limits on such a cutoff are found to be 450 and 280 GeV, assuming a power law with a simple exponential and a sub-exponential cutoff, respectively. It is concluded that none of the standard limitations (age, size, radiative losses) on the particle acceleration mechanism, assumed to be continuing at present, can explain the lack of VHE signal. The scenario in which particle acceleration has ceased some time ago is considered as an alternative explanation. The HE/VHE spectrum of Puppis A could then exhibit a break of non-radiative origin (as observed in several other interacting SNRs, albeit at somewhat higher energies), owing to the interaction with dense and neutral material, in particular towards the NE region.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Dalton, M. and Davids, I. D. and Degrange, B. and Deil, C. and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiaon, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadsch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, M. and Janiak, M. and Jankowsky, F. and Jung, I. and Kastendieck, M. A. and Katarzynski, Krzysztof and Katz, Uli and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nukri and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C-C and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, Manuela and Mitchell, A. M. W. and Moderski, R. and Mohamed, Mmahmoud and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Perez, J. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, Olaf and Renaud, M. and Reyes, R. de Los and Rieger, F. and Rob, L. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, F. and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, Christopher and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S.}, title = {The 2012 flare of PG 1553+113 seen with hess and Fermi-lat}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, volume = {802}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {HESS Collaboration}, issn = {0004-637X}, doi = {10.1088/0004-637X/802/1/65}, pages = {14}, year = {2015}, abstract = {Very high energy (VHE, E > 100 GeV)gamma-ray flaring activity of the high-frequency peaked BL Lac object PG 1553 + 113 has been detected by the H.E.S.S. telescopes. The flux of the source increased by a factor of 3 during the nights of 2012 April 26 and 27 with respect to the archival measurements with a hint of intra-night variability. No counterpart of this event has been detected in the Fermi-Large Area Telescope data. This pattern is consistent with VHE gamma(-)ray flaring being caused by the injection of ultrarelativistic particles, emitting.-rays at the highest energies. The dataset offers a unique opportunity to constrain the redshift of this source at z = 0.49 +/- 0.04 using a novel method based on Bayesian statistics. The indication of intra-night variability is used to introduce a novel method to probe for a possible Lorentz invariance violation (LIV), and to set limits on the energy scale at which Quantum Gravity (QG) effects causing LIV may arise. For the subluminal case, the derived limits are E-QG,E- 1 > 4.10 x 10(17) GeV and E-QG,E- 2 > 2.10 x 10(10) GeV for linear and quadratic LIV effects, respectively.}, language = {en} } @article{AbramowskiAharonianBenkhalietal.2014, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Biteau, Jonathan and Boettcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, C. and dewilt, P. and Djannati-Ata{\"i}, A. and Domainko, W. and Donath, A. and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Espigat, P. and Farnier, C. and Fegan, S. and Feinstein, F. and Fernandes, M. V. and Fernandez, D. and Fiasson, A. and Fontaine, G. and Foerster, A. and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Grudzinska, M. and Hadasch, D. and Haeffner, S. and Hahn, J. and Harris, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hervet, O. and Hillert, A. and Hinton, James Anthony and Hofmann, W. and Hofverberg, P. and Holler, M. and Horns, D. and Ivascenko, A. and Jacholkowska, A. and Jahn, C. and Jamrozy, Marek and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, Krzysztof and Katz, Uli and Kaufmann, S. and Khelifi, B. and Kieffer, M. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Krayzel, F. and Krueger, P. P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, T. and Lopatin, A. and Lu, C. -C. and Marandon, V. and Marcowith, Alexandre and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and McComb, T. J. L. and Mehault, J. and Meintjes, P. J. and Menzler, U. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, M. and Niemiec, J. and Nolan, S. J. and Oakes, L. and Odaka, H. and Ohm, S. and Opitz, B. and Ostrowski, M. and Oya, I. and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, H. and Puehlhofer, G. and Punch, Michael and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, A. and Reimer, Olaf and Renaud, M. and de los Reyes, R. and Rieger, F. and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, D. and Sanchez, David M. and Santangelo, A. and Schlickeiser, R. and Schuessler, Fabian and Schulz, A. and Schwanke, U. and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, M. and Trichard, C. and Valerius, K. and van Eldik, Christopher and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voelk, H. J. and Volpe, F. and Vorster, M. and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, M. and Weidinger, M. and Weitzel, Q. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zabalza, V. and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, H. -S. and Fukui, Y.}, title = {Diffuse Galactic gamma-ray emission with HESS}, series = {Physical review : D, Particles, fields, gravitation, and cosmology}, volume = {90}, journal = {Physical review : D, Particles, fields, gravitation, and cosmology}, number = {12}, publisher = {American Physical Society}, address = {College Park}, organization = {HESS Collaboration}, issn = {1550-7998}, doi = {10.1103/PhysRevD.90.122007}, pages = {8}, year = {2014}, abstract = {Diffuse gamma-ray emission is the most prominent observable signature of celestial cosmic-ray interactions at high energies. While already being investigated at GeVenergies over several decades, assessments of diffuse gamma-ray emission at TeVenergies remain sparse. After completion of the systematic survey of the inner Galaxy, the H.E.S.S. experiment is in a prime position to observe large-scale diffuse emission at TeVenergies. Data of the H.E.S.S. Galactic Plane Survey are investigated in regions off known gamma-ray sources. Corresponding gamma-ray flux measurements were made over an extensive grid of celestial locations. Longitudinal and latitudinal profiles of the observed gamma-ray fluxes show characteristic excess emission not attributable to known gamma-ray sources. For the first time large-scale gamma-ray emission along the Galactic plane using imaging atmospheric Cherenkov telescopes has been observed. While the background subtraction technique limits the ability to recover modest variation on the scale of the H.E.S.S. field of view or larger, which is characteristic of the inverse Compton scatter-induced Galactic diffuse emission, contributions of neutral pion decay as well as emission from unresolved gamma-ray sources can be recovered in the observed signal to a large fraction. Calculations show that the minimum gamma-ray emission from pi(0) decay represents a significant contribution to the total signal. This detection is interpreted as a mix of diffuse Galactic gamma-ray emission and unresolved sources.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2017, author = {Abdalla, Hassan E. and Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Andersson, T. and Anguner, Ekrem Oǧuzhan and Arakawa, M. and Arrieta, M. and Aubert, Pierre and Backes, Michael and Balzer, Arnim and Barnard, Michelle and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Blackwell, R. and B{\"o}ttcher, Markus and Boisson, Catherine and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Buechele, M. and Bulik, Tomasz and Capasso, M. and Carr, John and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chaves, Ryan C. G. and Chen, Andrew and Chevalier, J. and Coffaro, M. and Colafrancesco, Sergio and Cologna, Gabriele and Condon, B. and Conrad, Jan and Cui, Y. and Davids, I. D. and Decock, J. and Degrange, B. and Deil, C. and Devin, J. and de Wilt, P. and Dirson, L. and Djannati-Atai, A. and Domainko, W. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Garrigoux, T. and Giavitto, G. and Giebels, B. and Glicenstein, J. F. and Gottschall, D. and Goyal, A. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, James Anthony and Hofmann, W. and Hoischen, Clemens and Holch, Tim Lukas and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Janiak, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jogler, T. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Kruger, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Richter, S. and Rieger, F. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Salek, D. and Sanchez, David M. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Simoni, R. and Sol, H. and Spanier, F. and Spengler, G. and Spies, F. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Stycz, K. and Sushch, Iurii and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zywucka, N.}, title = {Measurement of the EBL spectral energy distribution using the VHE gamma-ray spectra of HESS blazars}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {606}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201731200}, pages = {11}, year = {2017}, abstract = {Very high-energy gamma rays (VHE, E greater than or similar to 100 GeV) propagating over cosmological distances can interact with the low-energy photons of the extragalactic background light (EBL) and produce electron-positron pairs. The transparency of the Universe to VHE gamma rays is then directly related to the spectral energy distribution (SED) of the EBL. The observation of features in the VHE energy spectra of extragalactic sources allows the EBL to be measured, which otherwise is very difficult. An EBL model-independent measurement of the EBL SED with the H.E.S.S. array of Cherenkov telescopes is presented. It was obtained by extracting the EBL absorption signal from the reanalysis of high-quality spectra of blazars. From H.E.S.S. data alone the EBL signature is detected at a significance of 9.5 sigma, and the intensity of the EBL obtained in different spectral bands is presented together with the associated gamma-ray horizon.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2017, author = {Abdalla, Hassan E. and Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Anguner, Ekrem Oǧuzhan and Arakawa, M. and Arrieta, M. and Aubert, Pierre and Backes, Michael and Balzer, Arnim and Barnard, Michelle and Becherini, Yvonne and Tjus, J. Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Blackwell, R. and B{\"o}ttcher, Markus and Boisson, Catherine and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Buechele, M. and Bulik, Tomasz and Capasso, M. and Caroff, S. and Carosi, A. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chaves, Ryan C. G. and Chen, Andrew and Chevalier, J. and Colafrancesco, Sergio and Condon, B. and Conrad, Jan and Davids, I. D. and Decock, J. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Donath, A. and Dutson, K. and Dyks, J. and Edwards, T. and Egberts, Kathrin and Emery, G. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, S. and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Garrigoux, T. and Gate, F. and Giavitto, G. and Giebels, B. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hawkes, J. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, James Anthony and Hofmann, W. and Hoischen, Clemens and Holch, Tim Lukas and Holler, M. and Horns, D. and Ivascenko, A. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jingo, M. and Jouvin, L. and Jung-Richardt, I. and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Klochkov, D. and Kluzniak, W. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, M. and Kruer, P. P. and Laffon, H. and Lamanna, G. and Lau, J. and Lees, J. -P. and Lefaucheur, J. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, T. and Lorentz, M. and Liu, R. and Lopez-Coto, R. and Lypova, I. and Malyshev, D. and Marandon, V. and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, M. and Meintjes, P. J. and Meyer, M. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Mora, K. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I. and Padovani, M. and Panter, M. and Parsons, R. D. and Pekeur, N. W. and Pelletier, G. and Perennes, C. and Petrucci, P. -O. and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V. and Poon, H. and Prokhorov, D. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and de los Reyes, R. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Saito, S. and Sanchez, David M. and Santangelo, A. and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Settimo, M. and Seyffert, A. S. and Shafi, N. and Shilon, I. and Shiningayamwe, K. and Simoni, R. and Sol, H. and Spanier, F. and Spir-Jacob, M. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Steppa, Constantin Beverly and Sushch, Iurii and Takahashi, T. and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsirou, M. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zorn, J. and Zywucka, N.}, title = {TeV Gamma-Ray Observations of the Binary Neutron Star Merger GW170817 with HESS}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {850}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {HESS Collaboration}, issn = {2041-8205}, doi = {10.3847/2041-8213/aa97d2}, pages = {628 -- 650}, year = {2017}, abstract = {We search for high-energy gamma-ray emission from the binary neutron star merger GW170817 with the H.E.S.S. Imaging Air Cherenkov Telescopes. The observations presented here have been obtained starting only 5.3 hr after GW170817. The H.E.S.S. target selection identified regions of high probability to find a counterpart of the gravitational-wave event. The first of these regions contained the counterpart SSS17a that has been identified in the optical range several hours after our observations. We can therefore present the first data obtained by a ground-based pointing instrument on this object. A subsequent monitoring campaign with the H.E.S.S. telescopes extended over several days, covering timescales from 0.22 to 5.2 days and energy ranges between 270 GeV to 8.55 TeV. No significant gamma-ray emission has been found. The derived upper limits on the very-high-energy gamma-ray flux for the first time constrain non-thermal, high-energy emission following the merger of a confirmed binary neutron star system.}, language = {en} } @article{TiegsCostelloIskenetal.2019, author = {Tiegs, Scott D. and Costello, David M. and Isken, Mark W. and Woodward, Guy and McIntyre, Peter B. and Gessner, Mark O. and Chauvet, Eric and Griffiths, Natalie A. and Flecker, Alex S. and Acuna, Vicenc and Albarino, Ricardo and Allen, Daniel C. and Alonso, Cecilia and Andino, Patricio and Arango, Clay and Aroviita, Jukka and Barbosa, Marcus V. M. and Barmuta, Leon A. and Baxter, Colden V. and Bell, Thomas D. C. and Bellinger, Brent and Boyero, Luz and Brown, Lee E. and Bruder, Andreas and Bruesewitz, Denise A. and Burdon, Francis J. and Callisto, Marcos and Canhoto, Cristina and Capps, Krista A. and Castillo, Maria M. and Clapcott, Joanne and Colas, Fanny and Colon-Gaud, Checo and Cornut, Julien and Crespo-Perez, Veronica and Cross, Wyatt F. and Culp, Joseph M. and Danger, Michael and Dangles, Olivier and de Eyto, Elvira and Derry, Alison M. and Diaz Villanueva, Veronica and Douglas, Michael M. and Elosegi, Arturo and Encalada, Andrea C. and Entrekin, Sally and Espinosa, Rodrigo and Ethaiya, Diana and Ferreira, Veronica and Ferriol, Carmen and Flanagan, Kyla M. and Fleituch, Tadeusz and Shah, Jennifer J. Follstad and Frainer, Andre and Friberg, Nikolai and Frost, Paul C. and Garcia, Erica A. and Lago, Liliana Garcia and Garcia Soto, Pavel Ernesto and Ghate, Sudeep and Giling, Darren P. and Gilmer, Alan and Goncalves, Jose Francisco and Gonzales, Rosario Karina and Graca, Manuel A. S. and Grace, Mike and Grossart, Hans-Peter and Guerold, Francois and Gulis, Vlad and Hepp, Luiz U. and Higgins, Scott and Hishi, Takuo and Huddart, Joseph and Hudson, John and Imberger, Samantha and Iniguez-Armijos, Carlos and Iwata, Tomoya and Janetski, David J. and Jennings, Eleanor and Kirkwood, Andrea E. and Koning, Aaron A. and Kosten, Sarian and Kuehn, Kevin A. and Laudon, Hjalmar and Leavitt, Peter R. and Lemes da Silva, Aurea L. and Leroux, Shawn J. and Leroy, Carri J. and Lisi, Peter J. and MacKenzie, Richard and Marcarelli, Amy M. and Masese, Frank O. and Mckie, Brendan G. and Oliveira Medeiros, Adriana and Meissner, Kristian and Milisa, Marko and Mishra, Shailendra and Miyake, Yo and Moerke, Ashley and Mombrikotb, Shorok and Mooney, Rob and Moulton, Tim and Muotka, Timo and Negishi, Junjiro N. and Neres-Lima, Vinicius and Nieminen, Mika L. and Nimptsch, Jorge and Ondruch, Jakub and Paavola, Riku and Pardo, Isabel and Patrick, Christopher J. and Peeters, Edwin T. H. M. and Pozo, Jesus and Pringle, Catherine and Prussian, Aaron and Quenta, Estefania and Quesada, Antonio and Reid, Brian and Richardson, John S. and Rigosi, Anna and Rincon, Jose and Risnoveanu, Geta and Robinson, Christopher T. and Rodriguez-Gallego, Lorena and Royer, Todd V. and Rusak, James A. and Santamans, Anna C. and Selmeczy, Geza B. and Simiyu, Gelas and Skuja, Agnija and Smykla, Jerzy and Sridhar, Kandikere R. and Sponseller, Ryan and Stoler, Aaron and Swan, Christopher M. and Szlag, David and Teixeira-de Mello, Franco and Tonkin, Jonathan D. and Uusheimo, Sari and Veach, Allison M. and Vilbaste, Sirje and Vought, Lena B. M. and Wang, Chiao-Ping and Webster, Jackson R. and Wilson, Paul B. and Woelfl, Stefan and Xenopoulos, Marguerite A. and Yates, Adam G. and Yoshimura, Chihiro and Yule, Catherine M. and Zhang, Yixin X. and Zwart, Jacob A.}, title = {Global patterns and drivers of ecosystem functioning in rivers and riparian zones}, series = {Science Advances}, volume = {5}, journal = {Science Advances}, number = {1}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {2375-2548}, doi = {10.1126/sciadv.aav0486}, pages = {8}, year = {2019}, abstract = {River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized at the global scale. In response, we used a peer-sourced research network and a highly standardized carbon processing assay to conduct a global-scale field experiment in greater than 1000 river and riparian sites. We found that Earth's biomes have distinct carbon processing signatures. Slow processing is evident across latitudes, whereas rapid rates are restricted to lower latitudes. Both the mean rate and variability decline with latitude, suggesting temperature constraints toward the poles and greater roles for other environmental drivers (e.g., nutrient loading) toward the equator. These results and data set the stage for unprecedented "next-generation biomonitoring" by establishing baselines to help quantify environmental impacts to the functioning of ecosystems at a global scale.}, language = {en} } @article{AbdallaAbramowskiAharonianetal.2016, author = {Abdalla, Hassan E. and Abramowski, Attila and Aharonian, Felix A. and Benkhali, Fai{\c{c}}al Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Arrieta, M. and Aubert, Pierre and Backes, Michael and Balzer, Arnim and Barnard, Michelle and Becherini, Yvonne and Tjus, Julia Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, K. and Birsin, E. and Blackwell, R. and Bottcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Capasso, M. and Carr, John and Casanova, Sabrina and Chakraborty, N. and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chen, Andrew and Chevalier, J. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Condon, B. and Conrad, Jan and Couturier, C. and Cui, Y. and Davids, I. D. and Degrange, B. and Deil, Christoph and deWilt, P. and Djannati-Atai, Arache and Domainko, Wilfried and Donath, Axel and Dubus, Guillaume and Dutson, Kate and Dyks, J. and Dyrda, M. and Edwards, T. and Egberts, Kathrin and Eger, P. and Ernenwein, J. -P. and Eschbach, S. and Farnier, C. and Fegan, Stuart and Fernandes, M. V. and Fiasson, A. and Fontaine, G. and Foerster, A. and Funk, S. and F{\"u}ßling, Matthias and Gabici, Stefano and Gajdus, M. and Gallant, Y. A. and Garrigoux, T. and Giavitto, Gianluca and Giebels, B. and Glicenstein, J. F. and Gottschall, Daniel and Goyal, A. and Grondin, M. -H. and Grudzinska, M. and Hadasch, Daniela and Hahn, J. and Hawkes, J. and Heinzelmann, G. and Henri, Gilles and Hermann, G. and Hervet, Olivier and Hillert, A. and Hinton, James Anthony and Hofmann, Werner and Hoischen, Clemens and Holler, M. and Horns, D. and Ivascenko, Alex and Jacholkowska, A. and Jamrozy, Marek and Janiak, M. and Jankowsky, D. and Jankowsky, Felix and Jingo, M. and Jogler, Tobias and Jouvin, Lea and Jung-Richardt, Ira and Kastendieck, M. A. and Katarzynski, Krzysztof and Katz, Uli and Kerszberg, D. and Khelifi, B. and Kieffer, M. and King, J. and Klepser, S. and Klochkov, Dmitry and Kluzniak, W. and Kolitzus, D. and Komin, Nu. and Kosack, K. and Krakau, S. and Kraus, Michael and Krayzel, F. and Kruger, P. P. and Laffon, H. and Lamanna, G. and Lau, Jeanie and Lees, J. -P. and Lefaucheur, J. and Lefranc, V. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Leser, Eva and Lohse, Thomas and Lorentz, M. and Lui, R. and Lypova, Iryna and Marandon, Vincent and Marcowith, Alexandre and Mariaud, C. and Marx, R. and Maurin, G. and Maxted, N. and Mayer, Michael and Meintjes, Petrus Johannes and Menzler, U. and Meyer, Manuel and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, T. and de Naurois, Mathieu and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, Hirokazu and Ohm, Stefan and Oettl, S. and Ostrowski, M. and Oya, I. and Padovani, Marco and Panter, M. and Parsons, R. D. and Arribas, M. Paz and Pekeur, N. W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, Helen and Prokhorov, Dmitry and Prokoph, Heike and Puehlhofer, Gerd and Punch, Michael and Quirrenbach, Andreas and Raab, S. and Reimer, Anita and Reimer, Olaf and Renaud, M. and de los Reyes, R. and Rieger, Frank and Romoli, Carlo and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, V. and Salek, David and Sanchez, David A. and Santangelo, Andrea and Sasaki, Manami and Schlickeiser, Reinhard and Schussler, F. and Schulz, Andreas and Schwanke, U. and Schwemmer, S. and Seyffert, A. S. and Shafi, N. and Simoni, R. and Sol, H. and Spanier, Felix and Spengler, G. and Spiess, F. and Stawarz, Lukasz and Steenkamp, R. and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, Martin and Trichard, C. and Tuffs, R. and van der Walt, Johan and van Eldik, Christopher and van Soelen, Brian and Vasileiadis, Georges and Veh, J. and Venter, C. and Viana, A. and Vincent, P. and Vink, Jacco and Voisin, F. and Voelk, Heinrich J. and Vuillaume, Thomas and Wadiasingh, Z. and Wagner, Stefan J. and Wagner, P. and Wagner, R. M. and White, R. and Wierzcholska, Alicja and Willmann, P. and Woernlein, A. and Wouters, Denis and Yang, R. and Zabalza, Victor and Zaborov, D. and Zacharias, M. and Zdziarski, A. A. and Zech, Andreas and Zefi, F. and Ziegler, A. and Zywucka, Natalia}, title = {Search for Dark Matter Annihilations towards the Inner Galactic Halo from 10 Years of Observations with HESS}, series = {Physical review letters}, volume = {117}, journal = {Physical review letters}, publisher = {American Physical Society}, address = {College Park}, organization = {HESS Collaboration}, issn = {0031-9007}, doi = {10.1103/PhysRevLett.117.111301}, pages = {6}, year = {2016}, abstract = {The inner region of the Milky Way halo harbors a large amount of dark matter (DM). Given its proximity, it is one of the most promising targets to look for DM. We report on a search for the annihilations of DM particles using gamma-ray observations towards the inner 300 pc of the Milky Way, with the H.E.S.S. array of ground-based Cherenkov telescopes. The analysis is based on a 2D maximum likelihood method using Galactic Center (GC) data accumulated by H.E.S.S. over the last 10 years (2004-2014), and does not show any significant gamma-ray signal above background. Assuming Einasto and Navarro-Frenk-White DM density profiles at the GC, we derive upper limits on the annihilation cross section . These constraints are the strongest obtained so far in the TeV DM mass range and improve upon previous limits by a factor 5. For the Einasto profile, the constraints reach values of 6 x 10(-26) cm(3) s(-1) in the W+W- channel for a DM particle mass of 1.5 TeV, and 2 x 10(-26) cm(3) s(-1) in the tau(+)tau(-) channel for a 1 TeV mass. For the first time, ground-based gamma-ray observations have reached sufficient sensitivity to probe values expected from the thermal relic density for TeV DM particles.}, language = {en} } @misc{AbramowskiAharonianBenkhalietal.2015, author = {Abramowski, Attila and Aharonian, Felix A. and Benkhali, Faical Ait and Akhperjanian, A. G. and Ang{\"u}ner, Ekrem Oǧuzhan and Backes, Michael and Balenderan, Shangkari and Balzer, Arnim and Barnacka, Anna and Becherini, Yvonne and Tjus, Julia Becker and Berge, David and Bernhard, Sabrina and Bernl{\"o}hr, Konrad and Birsin, E. and Biteau, Jonathan and B{\"o}ttcher, Markus and Boisson, Catherine and Bolmont, J. and Bordas, Pol and Bregeon, Johan and Brun, Francois and Brun, Pierre and Bryan, Mark and Bulik, Tomasz and Carrigan, Svenja and Casanova, Sabrina and Chadwick, Paula M. and Chakraborty, Nachiketa and Chalme-Calvet, R. and Chaves, Ryan C. G. and Chretien, M. and Colafrancesco, Sergio and Cologna, Gabriele and Conrad, Jan and Couturier, Claire and Cui, Yudong and Davids, Isak Delberth and Degrange, Bernhard and Deil, Christoph and deWilt, P. and Djannati-Ata{\"i}, A. and Domainko, Wilfried and Donath, Axel and Dubus, G. and Dutson, K. and Dyks, J. and Dyrda, M. and Edwards, Tanya and Egberts, Kathrin and Eger, Peter and Espigat, P. and Farnier, C. and Fegan, Stephen and Feinstein, Fabrice and Fernandes, Milton Virgilio and Fernandez, Diane and Fiasson, A. and Fontaine, Gerard and F{\"o}rster, Andreas and Fuessling, M. and Gabici, S. and Gajdus, M. and Gallant, Yves A. and Garrigoux, Tania and Giavitto, G. and Giebels, Berrie and Glicenstein, Jean-Francois and Gottschall, Daniel and Grondin, M. -H. and Grudzinska, M. and Hadasch, Daniela and Haeffner, S. and Hahn, Joachim and Harris, Jonathan and Heinzelmann, G{\"o}tz and Henri, G. and Hermann, German and Hervet, O. and Hillert, Andreas and Hinton, James Anthony and Hofmann, Werner and Hofverberg, Petter and Holler, Markus and Horns, Dieter and Ivascenko, Alex and Jacholkowska, A. and Jahn, C. and Jamrozy, Marek and Janiak, M. and Jankowsky, F. and Jung-Richardt, I. and Kastendieck, Max Anton and Katarzynski, K. and Katz, U. and Kaufmann, S. and Khelifi, B. and Kieffer, Michel and Klepser, S. and Klochkov, Dmitry and Kluzniak, W. and Kolitzus, David and Komin, Nu and Kosack, Karl and Krakau, Steffen and Krayzel, F. and Krueger, Pat P. and Laffon, H. and Lamanna, G. and Lefaucheur, J. and Lefranc, Valentin and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Lohse, Thomas and Lopatin, A. and Lu, Chia-Chun and Marandon, Vincent and Marcowith, Alexandre and Marx, Ramin and Maurin, G. and Maxted, Nigel and Mayer, Michael and McComb, T. J. Lowry and Mehault, J. and Meintjes, P. J. and Menzler, Ulf and Meyer, M. and Mitchell, Alison M. W. and Moderski, R. and Mohamed, M. and Mora, K. and Moulin, Emmanuel and Murach, Thomas and de Naurois, Mathieu and Niemiec, J. and Nolan, Sam J. and Oakes, Louise and Odaka, Hirokazu and Ohm, S. and Optiz, Bj{\"o}rn and Ostrowski, Michal and Oya, I. and Panter, Michael and Parsons, R. Daniel and Arribas, M. Paz and Pekeur, Nikki W. and Pelletier, G. and Petrucci, P. -O. and Peyaud, B. and Pita, S. and Poon, Helen and P{\"u}hlhofer, Gerd and Punch, M. and Quirrenbach, A. and Raab, S. and Reichardt, I. and Reimer, Anita and Reimer, Olaf and Renaud, Metz and de los Reyes, Raquel and Rieger, Frank and Romoli, C. and Rosier-Lees, S. and Rowell, G. and Rudak, B. and Rulten, C. B. and Sahakian, Vardan and Salek, D. and Sanchez, David M. and Santangelo, Andrea and Schlickeiser, Reinhard and Schuessler, F. and Schulz, A. and Schwanke, Ullrich and Schwarzburg, S. and Schwemmer, S. and Sol, H. and Spanier, Felix and Spengler, G. and Spies, Franziska and Stawarz, Lukasz and Steenkamp, Riaan and Stegmann, Christian and Stinzing, F. and Stycz, K. and Sushch, Iurii and Tavernet, J. -P. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tluczykont, Martin and Trichard, C. and Valerius, K. and van Eldik, C. and van Soelen, B. and Vasileiadis, Georges and Veh, J. and Venter, Christo and Viana, Aion and Vincent, P. and Vink, Jacco and V{\"o}lk, Heinrich J. and Volpe, Francesca and Vorster, Martine and Vuillaume, T. and Wagner, S. J. and Wagner, P. and Wagner, R. M. and Ward, Martin and Weidinger, Matthias and Weitzel, Quirin and White, R. and Wierzcholska, A. and Willmann, P. and Woernlein, A. and Wouters, D. and Yang, Ruizhi and Zabalza, Victor and Zaborov, Dmitry and Zacharias, M. and Zdziarski, A. A. and Zech, Alraune and Zechlin, Hannes -S.}, title = {H.E.S.S. detection of TeV emission from the interaction region between the supernova remnant G349.7+0.2 and a molecular cloud (vol 574, A100, 2015)}, series = {Astronomy and astrophysics : an international weekly journal}, volume = {580}, journal = {Astronomy and astrophysics : an international weekly journal}, publisher = {EDP Sciences}, address = {Les Ulis}, organization = {HESS Collaboration}, issn = {1432-0746}, doi = {10.1051/0004-6361/201425070e}, pages = {2}, year = {2015}, language = {en} } @article{MiddeldorpMahajanHorikoshietal.2019, author = {Middeldorp, Christel M. and Mahajan, Anubha and Horikoshi, Momoko and Robertson, Neil R. and Beaumont, Robin N. and Bradfield, Jonathan P. and Bustamante, Mariona and Cousminer, Diana L. and Day, Felix R. and De Silva, N. Maneka and Guxens, Monica and Mook-Kanamori, Dennis O. and St Pourcain, Beate and Warrington, Nicole M. and Adair, Linda S. and Ahlqvist, Emma and Ahluwalia, Tarunveer Singh and Almgren, Peter and Ang, Wei and Atalay, Mustafa and Auvinen, Juha and Bartels, Meike and Beckmann, Jacques S. and Bilbao, Jose Ramon and Bond, Tom and Borja, Judith B. and Cavadino, Alana and Charoen, Pimphen and Chen, Zhanghua and Coin, Lachlan and Cooper, Cyrus and Curtin, John A. and Custovic, Adnan and Das, Shikta and Davies, Gareth E. and Dedoussis, George V. and Duijts, Liesbeth and Eastwood, Peter R. and Eliasen, Anders U. and Elliott, Paul and Eriksson, Johan G. and Estivill, Xavier and Fadista, Joao and Fedko, Iryna O. and Frayling, Timothy M. and Gaillard, Romy and Gauderman, W. James and Geller, Frank and Gilliland, Frank and Gilsanz, Vincente and Granell, Raquel and Grarup, Niels and Groop, Leif and Hadley, Dexter and Hakonarson, Hakon and Hansen, Torben and Hartman, Catharina A. and Hattersley, Andrew T. and Hayes, M. Geoffrey and Hebebrand, Johannes and Heinrich, Joachim and Helgeland, Oyvind and Henders, Anjali K. and Henderson, John and Henriksen, Tine B. and Hirschhorn, Joel N. and Hivert, Marie-France and Hocher, Berthold and Holloway, John W. and Holt, Patrick and Hottenga, Jouke-Jan and Hypponen, Elina and Iniguez, Carmen and Johansson, Stefan and Jugessur, Astanand and Kahonen, Mika and Kalkwarf, Heidi J. and Kaprio, Jaakko and Karhunen, Ville and Kemp, John P. and Kerkhof, Marjan and Koppelman, Gerard H. and Korner, Antje and Kotecha, Sailesh and Kreiner-Moller, Eskil and Kulohoma, Benard and Kumar, Ashish and Kutalik, Zoltan and Lahti, Jari and Lappe, Joan M. and Larsson, Henrik and Lehtimaki, Terho and Lewin, Alexandra M. and Li, Jin and Lichtenstein, Paul and Lindgren, Cecilia M. and Lindi, Virpi and Linneberg, Allan and Liu, Xueping and Liu, Jun and Lowe, William L. and Lundstrom, Sebastian and Lyytikainen, Leo-Pekka and Ma, Ronald C. W. and Mace, Aurelien and Magi, Reedik and Magnus, Per and Mamun, Abdullah A. and Mannikko, Minna and Martin, Nicholas G. and Mbarek, Hamdi and McCarthy, Nina S. and Medland, Sarah E. and Melbye, Mads and Melen, Erik and Mohlke, Karen L. and Monnereau, Claire and Morgen, Camilla S. and Morris, Andrew P. and Murray, Jeffrey C. and Myhre, Ronny and Najman, Jackob M. and Nivard, Michel G. and Nohr, Ellen A. and Nolte, Ilja M. and Ntalla, Ioanna and Oberfield, Sharon E. and Oken, Emily and Oldehinkel, Albertine J. and Pahkala, Katja and Palviainen, Teemu and Panoutsopoulou, Kalliope and Pedersen, Oluf and Pennell, Craig E. and Pershagen, Goran and Pitkanen, Niina and Plomin, Robert and Power, Christine and Prasad, Rashmi B. and Prokopenko, Inga and Pulkkinen, Lea and Raikkonen, Katri and Raitakari, Olli T. and Reynolds, Rebecca M. and Richmond, Rebecca C. and Rivadeneira, Fernando and Rodriguez, Alina and Rose, Richard J. and Salem, Rany and Santa-Marina, Loreto and Saw, Seang-Mei and Schnurr, Theresia M. and Scott, James G. and Selzam, Saskia and Shepherd, John A. and Simpson, Angela and Skotte, Line and Sleiman, Patrick M. A. and Snieder, Harold and Sorensen, Thorkild I. A. and Standl, Marie and Steegers, Eric A. P. and Strachan, David P. and Straker, Leon and Strandberg, Timo and Taylor, Michelle and Teo, Yik-Ying and Thiering, Elisabeth and Torrent, Maties and Tyrrell, Jessica and Uitterlinden, Andre G. and van Beijsterveldt, Toos and van der Most, Peter J. and van Duijn, Cornelia M. and Viikari, Jorma and Vilor-Tejedor, Natalia and Vogelezang, Suzanne and Vonk, Judith M. and Vrijkotte, Tanja G. M. and Vuoksimaa, Eero and Wang, Carol A. and Watkins, William J. and Wichmann, H-Erich and Willemsen, Gonneke and Williams, Gail M. and Wilson, James F. and Wray, Naomi R. and Xu, Shujing and Xu, Cheng-Jian and Yaghootkar, Hanieh and Yi, Lu and Zafarmand, Mohammad Hadi and Zeggini, Eleftheria and Zemel, Babette S. and Hinney, Anke and Lakka, Timo A. and Whitehouse, Andrew J. O. and Sunyer, Jordi and Widen, Elisabeth E. and Feenstra, Bjarke and Sebert, Sylvain and Jacobsson, Bo and Njolstad, Pal R. and Stoltenberg, Camilla and Smith, George Davey and Lawlor, Debbie A. and Paternoster, Lavinia and Timpson, Nicholas J. and Ong, Ken K. and Bisgaard, Hans and Bonnelykke, Klaus and Jaddoe, Vincent W. V. and Tiemeier, Henning and Jarvelin, Marjo-Riitta and Evans, David M. and Perry, John R. B. and Grant, Struan F. A. and Boomsma, Dorret I. and Freathy, Rachel M. and McCarthy, Mark I. and Felix, Janine F.}, title = {The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia}, series = {European journal of epidemiology}, volume = {34}, journal = {European journal of epidemiology}, number = {3}, publisher = {Springer}, address = {Dordrecht}, organization = {EArly Genetics Lifecourse EGG Consortium EGG Membership EAGLE Membership}, issn = {0393-2990}, doi = {10.1007/s10654-019-00502-9}, pages = {279 -- 300}, year = {2019}, abstract = {The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. The majority of the participating cohorts are longitudinal population-based samples, but other cohorts with data on early childhood phenotypes are also involved. Cohorts often have a broad focus and collect(ed) data on various somatic and psychiatric traits as well as environmental factors. Genetic variants have been successfully identified for multiple traits, for example, birth weight, atopic dermatitis, childhood BMI, allergic sensitization, and pubertal growth. Furthermore, the results have shown that genetic factors also partly underlie the association with adult traits. As sample sizes are still increasing, it is expected that future analyses will identify additional variants. This, in combination with the development of innovative statistical methods, will provide detailed insight on the mechanisms underlying the transition from childhood to adult disorders. Both consortia welcome new collaborations. Policies and contact details are available from the corresponding authors of this manuscript and/or the consortium websites.}, language = {en} } @article{IkramFornageSmithetal.2012, author = {Ikram, M. Arfan and Fornage, Myriam and Smith, Albert V. and Seshadri, Sudha and Schmidt, Reinhold and Debette, Stephanie and Vrooman, Henri A. and Sigurdsson, Sigurdur and Ropele, Stefan and Taal, H. Rob and Mook-Kanamori, Dennis O. and Coker, Laura H. and Longstreth, W. T. and Niessen, Wiro J. and DeStefano, Anita L. and Beiser, Alexa and Zijdenbos, Alex P. and Struchalin, Maksim and Jack, Clifford R. and Rivadeneira, Fernando and Uitterlinden, Andre G. and Knopman, David S. and Hartikainen, Anna-Liisa and Pennell, Craig E. and Thiering, Elisabeth and Steegers, Eric A. P. and Hakonarson, Hakon and Heinrich, Joachim and Palmer, Lyle J. and Jarvelin, Marjo-Riitta and McCarthy, Mark I. and Grant, Struan F. A. and St Pourcain, Beate and Timpson, Nicholas J. and Smith, George Davey and Sovio, Ulla and Nalls, Mike A. and Au, Rhoda and Hofman, Albert and Gudnason, Haukur and van der Lugt, Aad and Harris, Tamara B. and Meeks, William M. and Vernooij, Meike W. and van Buchem, Mark A. and Catellier, Diane and Jaddoe, Vincent W. V. and Gudnason, Vilmundur and Windham, B. Gwen and Wolf, Philip A. and van Duijn, Cornelia M. and Mosley, Thomas H. and Schmidt, Helena and Launer, Lenore J. and Breteler, Monique M. B. and DeCarli, Charles and Adair, Linda S. and Ang, Wei and Atalay, Mustafa and vanBeijsterveldt, Toos and Bergen, Nienke and Benke, Kelly and Berry, Diane J. and Coin, Lachlan and Davis, Oliver S. P. and Elliott, Paul and Flexeder, Claudia and Frayling, Tim and Gaillard, Romy and Groen-Blokhuis, Maria and Goh, Liang-Kee and Haworth, Claire M. A. and Hadley, Dexter and Hebebrand, Johannes and Hinney, Anke and Hirschhorn, Joel N. and Holloway, John W. and Holst, Claus and Hottenga, Jouke Jan and Horikoshi, Momoko and Huikari, Ville and Hypponen, Elina and Kilpelainen, Tuomas O. and Kirin, Mirna and Kowgier, Matthew and Lakka, Hanna-Maaria and Lange, Leslie A. and Lawlor, Debbie A. and Lehtimaki, Terho and Lewin, Alex and Lindgren, Cecilia and Lindi, Virpi and Maggi, Reedik and Marsh, Julie and Middeldorp, Christel and Millwood, Iona and Murray, Jeffrey C. and Nivard, Michel and Nohr, Ellen Aagaard and Ntalla, Ioanna and Oken, Emily and Panoutsopoulou, Kalliope and Pararajasingham, Jennifer and Rodriguez, Alina and Salem, Rany M. and Sebert, Sylvain and Siitonen, Niina and Strachan, David P. and Teo, Yik-Ying and Valcarcel, Beatriz and Willemsen, Gonneke and Zeggini, Eleftheria and Boomsma, Dorret I. and Cooper, Cyrus and Gillman, Matthew and Hocher, Berthold and Lakka, Timo A. and Mohlke, Karen L. and Dedoussis, George V. and Ong, Ken K. and Pearson, Ewan R. and Price, Thomas S. and Power, Chris and Raitakari, Olli T. and Saw, Seang-Mei and Scherag, Andre and Simell, Olli and Sorensen, Thorkild I. A. and Wilson, James F.}, title = {Common variants at 6q22 and 17q21 are associated with intracranial volume}, series = {Nature genetics}, volume = {44}, journal = {Nature genetics}, number = {5}, publisher = {Nature Publ. Group}, address = {New York}, organization = {Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genomic Ep}, issn = {1061-4036}, doi = {10.1038/ng.2245}, pages = {539 -- +}, year = {2012}, abstract = {During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect different genetic influences. Our genome-wide association study (GWAS) in 8,175 community-dwelling elderly persons did not reveal any associations at genome-wide significance (P < 5 x 10(-8)) for brain volume. In contrast, intracranial volume was significantly associated with two loci: rs4273712 (P = 3.4 x 10(-11)), a known height-associated locus on chromosome 6q22, and rs9915547 (P = 1.5 x 10(-12)), localized to the inversion on chromosome 17q21. We replicated the associations of these loci with intracranial volume in a separate sample of 1,752 elderly persons (P = 1.1 x 10(-3) for 6q22 and 1.2 x 10(-3) for 17q21). Furthermore, we also found suggestive associations of the 17q21 locus with head circumference in 10,768 children (mean age of 14.5 months). Our data identify two loci associated with head size, with the inversion at 17q21 also likely to be involved in attaining maximal brain size.}, language = {en} } @article{WarringtonBeaumontHorikoshietal.2019, author = {Warrington, Nicole and Beaumont, Robin and Horikoshi, Momoko and Day, Felix R. and Helgeland, {\O}yvind and Laurin, Charles and Bacelis, Jonas and Peng, Shouneng and Hao, Ke and Feenstra, Bjarke and Wood, Andrew R. and Mahajan, Anubha and Tyrrell, Jessica and Robertson, Neil R. and Rayner, N. William and Qiao, Zhen and Moen, Gunn-Helen and Vaudel, Marc and Marsit, Carmen and Chen, Jia and Nodzenski, Michael and Schnurr, Theresia M. and Zafarmand, Mohammad Hadi and Bradfield, Jonathan P. and Grarup, Niels and Kooijman, Marjolein N. and Li-Gao, Ruifang and Geller, Frank and Ahluwalia, Tarunveer Singh and Paternoster, Lavinia and Rueedi, Rico and Huikari, Ville and Hottenga, Jouke-Jan and Lyytik{\"a}inen, Leo-Pekka and Cavadino, Alana and Metrustry, Sarah and Cousminer, Diana L. and Wu, Ying and Thiering, Elisabeth Paula and Wang, Carol A. and Have, Christian Theil and Vilor-Tejedor, Natalia and Joshi, Peter K. and Painter, Jodie N. and Ntalla, Ioanna and Myhre, Ronny and Pitk{\"a}nen, Niina and van Leeuwen, Elisabeth M. and Joro, Raimo and Lagou, Vasiliki and Richmond, Rebecca C. and Espinosa, Ana and Barton, Sheila J. and Inskip, Hazel M. and Holloway, John W. and Santa-Marina, Loreto and Estivill, Xavier and Ang, Wei and Marsh, Julie A. and Reichetzeder, Christoph and Marullo, Letizia and Hocher, Berthold and Lunetta, Kathryn L. and Murabito, Joanne M. and Relton, Caroline L. and Kogevinas, Manolis and Chatzi, Leda and Allard, Catherine and Bouchard, Luigi and Hivert, Marie-France and Zhang, Ge and Muglia, Louis J. and Heikkinen, Jani and Morgen, Camilla S. and van Kampen, Antoine H. C. and van Schaik, Barbera D. C. and Mentch, Frank D. and Langenberg, Claudia and Scott, Robert A. and Zhao, Jing Hua and Hemani, Gibran and Ring, Susan M. and Bennett, Amanda J. and Gaulton, Kyle J. and Fernandez-Tajes, Juan and van Zuydam, Natalie R. and Medina-Gomez, Carolina and de Haan, Hugoline G. and Rosendaal, Frits R. and Kutalik, Zolt{\´a}n and Marques-Vidal, Pedro and Das, Shikta and Willemsen, Gonneke and Mbarek, Hamdi and M{\"u}ller-Nurasyid, Martina and Standl, Marie and Appel, Emil V. R. and Fonvig, Cilius Esmann and Trier, Caecilie and van Beijsterveldt, Catharina E. M. and Murcia, Mario and Bustamante, Mariona and Bon{\`a}s-Guarch, S{\´i}lvia and Hougaard, David M. and Mercader, Josep M. and Linneberg, Allan and Schraut, Katharina E. and Lind, Penelope A. and Medland, Sarah Elizabeth and Shields, Beverley M. and Knight, Bridget A. and Chai, Jin-Fang and Panoutsopoulou, Kalliope and Bartels, Meike and S{\´a}nchez, Friman and Stokholm, Jakob and Torrents, David and Vinding, Rebecca K. and Willems, Sara M. and Atalay, Mustafa and Chawes, Bo L. and Kovacs, Peter and Prokopenko, Inga and Tuke, Marcus A. and Yaghootkar, Hanieh and Ruth, Katherine S. and Jones, Samuel E. and Loh, Po-Ru and Murray, Anna and Weedon, Michael N. and T{\"o}njes, Anke and Stumvoll, Michael and Michaelsen, Kim Fleischer and Eloranta, Aino-Maija and Lakka, Timo A. and van Duijn, Cornelia M. and Kiess, Wieland and Koerner, Antje and Niinikoski, Harri and Pahkala, Katja and Raitakari, Olli T. and Jacobsson, Bo and Zeggini, Eleftheria and Dedoussis, George V. and Teo, Yik-Ying and Saw, Seang-Mei and Montgomery, Grant W. and Campbell, Harry and Wilson, James F. and Vrijkotte, Tanja G. M. and Vrijheid, Martine and de Geus, Eco J. C. N. and Hayes, M. Geoffrey and Kadarmideen, Haja N. and Holm, Jens-Christian and Beilin, Lawrence J. and Pennell, Craig E. and Heinrich, Joachim and Adair, Linda S. and Borja, Judith B. and Mohlke, Karen L. and Eriksson, Johan G. and Widen, Elisabeth E. and Hattersley, Andrew T. and Spector, Tim D. and Kaehoenen, Mika and Viikari, Jorma S. and Lehtimaeki, Terho and Boomsma, Dorret I. and Sebert, Sylvain and Vollenweider, Peter and Sorensen, Thorkild I. A. and Bisgaard, Hans and Bonnelykke, Klaus and Murray, Jeffrey C. and Melbye, Mads and Nohr, Ellen A. and Mook-Kanamori, Dennis O. and Rivadeneira, Fernando and Hofman, Albert and Felix, Janine F. and Jaddoe, Vincent W. V. and Hansen, Torben and Pisinger, Charlotta and Vaag, Allan A. and Pedersen, Oluf and Uitterlinden, Andre G. and Jarvelin, Marjo-Riitta and Power, Christine and Hypponen, Elina and Scholtens, Denise M. and Lowe, William L. and Smith, George Davey and Timpson, Nicholas J. and Morris, Andrew P. and Wareham, Nicholas J. and Hakonarson, Hakon and Grant, Struan F. A. and Frayling, Timothy M. and Lawlor, Debbie A. and Njolstad, Pal R. and Johansson, Stefan and Ong, Ken K. and McCarthy, Mark I. and Perry, John R. B. and Evans, David M. and Freathy, Rachel M.}, title = {Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors}, series = {Nature genetics}, volume = {51}, journal = {Nature genetics}, number = {5}, publisher = {Nature Publ. Group}, address = {New York}, organization = {EGG Consortium}, issn = {1061-4036}, pages = {804 -- +}, year = {2019}, abstract = {Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic health outcomes. In expanded genome-wide association analyses of own birth weight (n = 321,223) and offspring birth weight (n = 230,069 mothers), we identified 190 independent association signals (129 of which are novel). We used structural equation modeling to decompose the contributions of direct fetal and indirect maternal genetic effects, then applied Mendelian randomization to illuminate causal pathways. For example, both indirect maternal and direct fetal genetic effects drive the observational relationship between lower birth weight and higher later blood pressure: maternal blood pressure-raising alleles reduce offspring birth weight, but only direct fetal effects of these alleles, once inherited, increase later offspring blood pressure. Using maternal birth weight-lowering genotypes to proxy for an adverse intrauterine environment provided no evidence that it causally raises offspring blood pressure, indicating that the inverse birth weight-blood pressure association is attributable to genetic effects, and not to intrauterine programming.}, language = {en} } @article{BanksNishiyamaHasebeetal.2011, author = {Banks, Jo Ann and Nishiyama, Tomoaki and Hasebe, Mitsuyasu and Bowman, John L. and Gribskov, Michael and dePamphilis, Claude and Albert, Victor A. and Aono, Naoki and Aoyama, Tsuyoshi and Ambrose, Barbara A. and Ashton, Neil W. and Axtell, Michael J. and Barker, Elizabeth and Barker, Michael S. and Bennetzen, Jeffrey L. and Bonawitz, Nicholas D. and Chapple, Clint and Cheng, Chaoyang and Correa, Luiz Gustavo Guedes and Dacre, Michael and DeBarry, Jeremy and Dreyer, Ingo and Elias, Marek and Engstrom, Eric M. and Estelle, Mark and Feng, Liang and Finet, Cedric and Floyd, Sandra K. and Frommer, Wolf B. and Fujita, Tomomichi and Gramzow, Lydia and Gutensohn, Michael and Harholt, Jesper and Hattori, Mitsuru and Heyl, Alexander and Hirai, Tadayoshi and Hiwatashi, Yuji and Ishikawa, Masaki and Iwata, Mineko and Karol, Kenneth G. and Koehler, Barbara and Kolukisaoglu, Uener and Kubo, Minoru and Kurata, Tetsuya and Lalonde, Sylvie and Li, Kejie and Li, Ying and Litt, Amy and Lyons, Eric and Manning, Gerard and Maruyama, Takeshi and Michael, Todd P. and Mikami, Koji and Miyazaki, Saori and Morinaga, Shin-ichi and Murata, Takashi and M{\"u}ller-R{\"o}ber, Bernd and Nelson, David R. and Obara, Mari and Oguri, Yasuko and Olmstead, Richard G. and Onodera, Naoko and Petersen, Bent Larsen and Pils, Birgit and Prigge, Michael and Rensing, Stefan A. and Mauricio Riano-Pachon, Diego and Roberts, Alison W. and Sato, Yoshikatsu and Scheller, Henrik Vibe and Schulz, Burkhard and Schulz, Christian and Shakirov, Eugene V. and Shibagaki, Nakako and Shinohara, Naoki and Shippen, Dorothy E. and Sorensen, Iben and Sotooka, Ryo and Sugimoto, Nagisa and Sugita, Mamoru and Sumikawa, Naomi and Tanurdzic, Milos and Theissen, Guenter and Ulvskov, Peter and Wakazuki, Sachiko and Weng, Jing-Ke and Willats, William W. G. T. and Wipf, Daniel and Wolf, Paul G. and Yang, Lixing and Zimmer, Andreas D. and Zhu, Qihui and Mitros, Therese and Hellsten, Uffe and Loque, Dominique and Otillar, Robert and Salamov, Asaf and Schmutz, Jeremy and Shapiro, Harris and Lindquist, Erika and Lucas, Susan and Rokhsar, Daniel and Grigoriev, Igor V.}, title = {The selaginella genome identifies genetic changes associated with the evolution of vascular plants}, series = {Science}, volume = {332}, journal = {Science}, number = {6032}, publisher = {American Assoc. for the Advancement of Science}, address = {Washington}, issn = {0036-8075}, doi = {10.1126/science.1203810}, pages = {960 -- 963}, year = {2011}, abstract = {Vascular plants appeared similar to 410 million years ago, then diverged into several lineages of which only two survive: the euphyllophytes (ferns and seed plants) and the lycophytes. We report here the genome sequence of the lycophyte Selaginella moellendorffii (Selaginella), the first nonseed vascular plant genome reported. By comparing gene content in evolutionarily diverse taxa, we found that the transition from a gametophyte- to a sporophyte-dominated life cycle required far fewer new genes than the transition from a nonseed vascular to a flowering plant, whereas secondary metabolic genes expanded extensively and in parallel in the lycophyte and angiosperm lineages. Selaginella differs in posttranscriptional gene regulation, including small RNA regulation of repetitive elements, an absence of the trans-acting small interfering RNA pathway, and extensive RNA editing of organellar genes.}, language = {en} } @misc{HussBookhagenHuggeletal.2017, author = {Huss, Matthias and Bookhagen, Bodo and Huggel, C. and Jacobsen, Dean and Bradley, Raymond S. and Clague, J. J. and Vuille, Mathias and Buytaert, Wouter and Cayan, D. R. and Greenwood, G. and Mark, B. G. and Milner, A. M. and Weingartner, Rolf and Winder, M.}, title = {Toward mountains without permanent snow and ice}, series = {Earths future}, volume = {5}, journal = {Earths future}, publisher = {Wiley}, address = {Hoboken}, issn = {2328-4277}, doi = {10.1002/2016EF000514}, pages = {418 -- 435}, year = {2017}, abstract = {The cryosphere in mountain regions is rapidly declining, a trend that is expected to accelerate over the next several decades due to anthropogenic climate change. A cascade of effects will result, extending from mountains to lowlands with associated impacts on human livelihood, economy, and ecosystems. With rising air temperatures and increased radiative forcing, glaciers will become smaller and, in some cases, disappear, the area of frozen ground will diminish, the ratio of snow to rainfall will decrease, and the timing and magnitude of both maximum and minimum streamflow will change. These changes will affect erosion rates, sediment, and nutrient flux, and the biogeochemistry of rivers and proglacial lakes, all of which influence water quality, aquatic habitat, and biotic communities. Changes in the length of the growing season will allow low-elevation plants and animals to expand their ranges upward. Slope failures due to thawing alpine permafrost, and outburst floods from glacier-and moraine-dammed lakes will threaten downstream populations.Societies even well beyond the mountains depend on meltwater from glaciers and snow for drinking water supplies, irrigation, mining, hydropower, agriculture, and recreation. Here, we review and, where possible, quantify the impacts of anticipated climate change on the alpine cryosphere, hydrosphere, and biosphere, and consider the implications for adaptation to a future of mountains without permanent snow and ice.}, language = {en} } @misc{CohenCampisanoArrowsmithetal.2016, author = {Cohen, Abby and Campisano, Christopher and Arrowsmith, J. Ramon and Asrat, Asfawossen and Behrensmeyer, A. K. and Deino, A. and Feibel, C. and Hill, A. and Johnson, R. and Kingston, J. and Lamb, Henry F. and Lowenstein, T. and Noren, A. and Olago, D. and Owen, Richard Bernhart and Potts, R. and Reed, Kate and Renaut, R. and Sch{\"a}bitz, F. and Tiercelin, J.-J. and Trauth, Martin H. and Wynn, J. and Ivory, S. and Brady, K. and O'Grady, R. and Rodysill, J. and Githiri, J. and Russell, Joellen and Foerster, Verena and Dommain, Ren{\´e} and Rucina, J. S. and Deocampo, D. and Russell, J. and Billingsley, A. and Beck, C. and Dorenbeck, G. and Dullo, L. and Feary, D. and Garello, D. and Gromig, R. and Johnson, T. and Junginger, Annett and Karanja, M. and Kimburi, E. and Mbuthia, A. and McCartney, Tannis and McNulty, E. and Muiruri, V. and Nambiro, E. and Negash, E. W. and Njagi, D. and Wilson, J. N. and Rabideaux, N. and Raub, Timothy and Sier, Mark Jan and Smith, P. and Urban, J. and Warren, M. and Yadeta, M. and Yost, Chad and Zinaye, B.}, title = {The Hominin Sites and Paleolakes Drilling Project}, series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, journal = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe}, number = {611}, doi = {10.25932/publishup-41249}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-412498}, pages = {16}, year = {2016}, abstract = {The role that climate and environmental history may have played in influencing human evolution has been the focus of considerable interest and controversy among paleoanthropologists for decades. Prior attempts to understand the environmental history side of this equation have centered around the study of outcrop sediments and fossils adjacent to where fossil hominins (ancestors or close relatives of modern humans) are found, or from the study of deep sea drill cores. However, outcrop sediments are often highly weathered and thus are unsuitable for some types of paleoclimatic records, and deep sea core records come from long distances away from the actual fossil and stone tool remains. The Hominin Sites and Paleolakes Drilling Project (HSPDP) was developed to address these issues. The project has focused its efforts on the eastern African Rift Valley, where much of the evidence for early hominins has been recovered. We have collected about 2 km of sediment drill core from six basins in Kenya and Ethiopia, in lake deposits immediately adjacent to important fossil hominin and archaeological sites. Collectively these cores cover in time many of the key transitions and critical intervals in human evolutionary history over the last 4 Ma, such as the earliest stone tools, the origin of our own genus Homo, and the earliest anatomically modern Homo sapiens. Here we document the initial field, physical property, and core description results of the 2012-2014 HSPDP coring campaign.}, language = {en} } @article{HerreroThorntonMasonD'Crozetal.2020, author = {Herrero, Mario and Thornton, Philip K. and Mason-D'Croz, Daniel and Palmer, Jeda and Bodirsky, Benjamin Leon and Pradhan, Prajal and Barrett, Christopher B. and Benton, Tim G. and Hall, Andrew and Pikaar, Ilje and Bogard, Jessica R. and Bonnett, Graham D. and Bryan, Brett A. and Campbell, Bruce M. and Christensen, Svend and Clark, Michael and Fanzo, Jessica and Godde, Cecile M. and Jarvis, Andy and Loboguerrero, Ana Maria and Mathys, Alexander and McIntyre, C. Lynne and Naylor, Rosamond L. and Nelson, Rebecca and Obersteiner, Michael and Parodi, Alejandro and Popp, Alexander and Ricketts, Katie and Smith, Pete and Valin, Hugo and Vermeulen, Sonja J. and Vervoort, Joost and van Wijk, Mark and van Zanten, Hannah H. E. and West, Paul C. and Wood, Stephen A. and Rockstr{\"o}m, Johan}, title = {Articulating the effect of food systems innovation on the Sustainable Development Goals}, series = {The lancet Planetary health}, volume = {5}, journal = {The lancet Planetary health}, number = {1}, publisher = {Elsevier}, address = {Oxford}, issn = {2542-5196}, doi = {10.1016/S2542-5196(20)30277-1}, pages = {E50 -- E62}, year = {2020}, abstract = {Food system innovations will be instrumental to achieving multiple Sustainable Development Goals (SDGs). However, major innovation breakthroughs can trigger profound and disruptive changes, leading to simultaneous and interlinked reconfigurations of multiple parts of the global food system. The emergence of new technologies or social solutions, therefore, have very different impact profiles, with favourable consequences for some SDGs and unintended adverse side-effects for others. Stand-alone innovations seldom achieve positive outcomes over multiple sustainability dimensions. Instead, they should be embedded as part of systemic changes that facilitate the implementation of the SDGs. Emerging trade-offs need to be intentionally addressed to achieve true sustainability, particularly those involving social aspects like inequality in its many forms, social justice, and strong institutions, which remain challenging. Trade-offs with undesirable consequences are manageable through the development of well planned transition pathways, careful monitoring of key indicators, and through the implementation of transparent science targets at the local level.}, language = {en} } @misc{GorskiJungLietal.2020, author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.}, title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Reihe der Digital Engineering Fakult{\"a}t}, number = {19}, doi = {10.25932/publishup-56537}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-565379}, pages = {14}, year = {2020}, abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.}, language = {en} } @article{GorskiJungLietal.2020, author = {Gorski, Mathias and Jung, Bettina and Li, Yong and Matias-Garcia, Pamela R. and Wuttke, Matthias and Coassin, Stefan and Thio, Chris H. L. and Kleber, Marcus E. and Winkler, Thomas W. and Wanner, Veronika and Chai, Jin-Fang and Chu, Audrey Y. and Cocca, Massimiliano and Feitosa, Mary F. and Ghasemi, Sahar and Hoppmann, Anselm and Horn, Katrin and Li, Man and Nutile, Teresa and Scholz, Markus and Sieber, Karsten B. and Teumer, Alexander and Tin, Adrienne and Wang, Judy and Tayo, Bamidele O. and Ahluwalia, Tarunveer S. and Almgren, Peter and Bakker, Stephan J. L. and Banas, Bernhard and Bansal, Nisha and Biggs, Mary L. and Boerwinkle, Eric and B{\"o}ttinger, Erwin and Brenner, Hermann and Carroll, Robert J. and Chalmers, John and Chee, Miao-Li and Chee, Miao-Ling and Cheng, Ching-Yu and Coresh, Josef and de Borst, Martin H. and Degenhardt, Frauke and Eckardt, Kai-Uwe and Endlich, Karlhans and Franke, Andre and Freitag-Wolf, Sandra and Gampawar, Piyush and Gansevoort, Ron T. and Ghanbari, Mohsen and Gieger, Christian and Hamet, Pavel and Ho, Kevin and Hofer, Edith and Holleczek, Bernd and Foo, Valencia Hui Xian and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Josyula, Navya Shilpa and Kahonen, Mika and Khor, Chiea-Chuen and Koenig, Wolfgang and Kramer, Holly and Kraemer, Bernhard K. and Kuehnel, Brigitte and Lange, Leslie A. and Lehtimaki, Terho and Lieb, Wolfgang and Loos, Ruth J. F. and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Milaneschi, Yuri and Mishra, Pashupati P. and Mononen, Nina and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and O'Donoghue, Michelle L. and Orho-Melander, Marju and Pendergrass, Sarah A. and Penninx, Brenda W. J. H. and Preuss, Michael H. and Psaty, Bruce M. and Raffield, Laura M. and Raitakari, Olli T. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Rosenkranz, Alexander R. and Rossing, Peter and Rotter, Jerome and Sabanayagam, Charumathi and Schmidt, Helena and Schmidt, Reinhold and Schoettker, Ben and Schulz, Christina-Alexandra and Sedaghat, Sanaz and Shaffer, Christian M. and Strauch, Konstantin and Szymczak, Silke and Taylor, Kent D. and Tremblay, Johanne and Chaker, Layal and van der Harst, Pim and van der Most, Peter J. and Verweij, Niek and Voelker, Uwe and Waldenberger, Melanie and Wallentin, Lars and Waterworth, Dawn M. and White, Harvey D. and Wilson, James G. and Wong, Tien-Yin and Woodward, Mark and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Yan and Snieder, Harold and Wanner, Christoph and Boger, Carsten A. and Kottgen, Anna and Kronenberg, Florian and Pattaro, Cristian and Heid, Iris M.}, title = {Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline}, series = {Kidney international : official journal of the International Society of Nephrology}, volume = {99}, journal = {Kidney international : official journal of the International Society of Nephrology}, number = {4}, publisher = {Elsevier}, address = {New York}, organization = {Lifelines Cohort Study
Regeneron Genetics Ctr}, issn = {0085-2538}, doi = {10.1016/j.kint.2020.09.030}, pages = {926 -- 939}, year = {2020}, abstract = {Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with severe clinical endpoints. In contrast to cross-sectionally assessed eGFRcrea, the genetic basis for rapid eGFRcrea decline is largely unknown. To help define this, we meta-analyzed 42 genome-wide association studies from the Chronic Kidney Diseases Genetics Consortium and United Kingdom Biobank to identify genetic loci for rapid eGFRcrea decline. Two definitions of eGFRcrea decline were used: 3 mL/min/1.73m(2)/year or more ("Rapid3"; encompassing 34,874 cases, 107,090 controls) and eGFRcrea decline 25\% or more and eGFRcrea under 60 mL/min/1.73m(2) at follow-up among those with eGFRcrea 60 mL/min/1.73m(2) or more at baseline ("CKDi25"; encompassing 19,901 cases, 175,244 controls). Seven independent variants were identified across six loci for Rapid3 and/or CKDi25: consisting of five variants at four loci with genome-wide significance (near UMOD-PDILT (2), PRKAG2, WDR72, OR2S2) and two variants among 265 known eGFRcrea variants (near GATM, LARP4B). All these loci were novel for Rapid3 and/or CKDi25 and our bioinformatic follow-up prioritized variants and genes underneath these loci. The OR2S2 locus is novel for any eGFRcrea trait including interesting candidates. For the five genome-wide significant lead variants, we found supporting effects for annual change in blood urea nitrogen or cystatin-based eGFR, but not for GATM or (LARP4B). Individuals at high compared to those at low genetic risk (8-14 vs. 0-5 adverse alleles) had a 1.20-fold increased risk of acute kidney injury (95\% confidence interval 1.08-1.33). Thus, our identified loci for rapid kidney function decline may help prioritize therapeutic targets and identify mechanisms and individuals at risk for sustained deterioration of kidney function.}, language = {en} } @unpublished{AsendorpfConnerDeFruytetal.2013, author = {Asendorpf, Jens B. and Conner, Mark and De Fruyt, Filip and De Houwer, Jan and Denissen, Jaap J. A. and Fiedler, Klaus and Fiedler, Susann and Funder, David C. and Kliegl, Reinhold and Nosek, Brian A. and Perugini, Marco and Roberts, Brent W. and Schmitt, Manfred and Van Aken, Marcel A. G. and Weber, Hannelore and Wicherts, Jelte M.}, title = {Replication is more than hitting the lottery twice}, series = {European journal of personality}, volume = {27}, journal = {European journal of personality}, number = {2}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0890-2070}, pages = {138 -- 144}, year = {2013}, abstract = {The main goal of our target article was to provide concrete recommendations for improving the replicability of research findings. Most of the comments focus on this point. In addition, a few comments were concerned with the distinction between replicability and generalizability and the role of theory in replication. We address all comments within the conceptual structure of the target article and hope to convince readers that replication in psychological science amounts to much more than hitting the lottery twice.}, language = {en} } @article{AsendorpfConnerDeFruytetal.2013, author = {Asendorpf, Jens B. and Conner, Mark and De Fruyt, Filip and De Houwer, Jan and Denissen, Jaap J. A. and Fiedler, Klaus and Fiedler, Susann and Funder, David C. and Kliegl, Reinhold and Nosek, Brian A. and Perugini, Marco and Roberts, Brent W. and Schmitt, Manfred and vanAken, Marcel A. G. and Weber, Hannelore and Wicherts, Jelte M.}, title = {Recommendations for increasing replicability in psychology}, series = {European journal of personality}, volume = {27}, journal = {European journal of personality}, number = {2}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0890-2070}, doi = {10.1002/per.1919}, pages = {108 -- 119}, year = {2013}, abstract = {Replicability of findings is at the heart of any empirical science. The aim of this article is to move the current replicability debate in psychology towards concrete recommendations for improvement. We focus on research practices but also offer guidelines for reviewers, editors, journal management, teachers, granting institutions, and university promotion committees, highlighting some of the emerging and existing practical solutions that can facilitate implementation of these recommendations. The challenges for improving replicability in psychological science are systemic. Improvement can occur only if changes are made at many levels of practice, evaluation, and reward.}, language = {en} }