@article{FiehlerBannertBischoffetal.2011, author = {Fiehler, Katja and Bannert, Michael M. and Bischoff, Matthias and Blecker, Carlo and Stark, Rudolf and Vaitl, Dieter and Franz, Volker H. and Roesler, Frank}, title = {Working memory maintenance of grasp-target information in the human posterior parietal cortex}, series = {NeuroImage : a journal of brain function}, volume = {54}, journal = {NeuroImage : a journal of brain function}, number = {3}, publisher = {Elsevier}, address = {San Diego}, issn = {1053-8119}, doi = {10.1016/j.neuroimage.2010.09.080}, pages = {2401 -- 2411}, year = {2011}, abstract = {Event-related functional magnetic resonance imaging was applied to identify cortical areas involved in maintaining target information in working memory used for an upcoming grasping action. Participants had to grasp with their thumb and index finger of the dominant right hand three-dimensional objects of different size and orientation. Reaching-to-grasp movements were performed without visual feedback either immediately after object presentation or after a variable delay of 2-12 s. The right inferior parietal cortex demonstrated sustained neural activity throughout the delay, which overlapped with activity observed during encoding of the grasp target. Immediate and delayed grasping activated similar motor-related brain areas and showed no differential activity. The results suggest that the right inferior parietal cortex plays an important functional role in working memory maintenance of grasp-related information. Moreover, our findings confirm the assumption that brain areas engaged in maintaining information are also involved in encoding the same information, and thus extend previous findings on working memory function of the posterior parietal cortex in saccadic behavior to reach-to-grasp movements.}, language = {en} } @article{SteinbergFischerKiuliesetal.1999, author = {Steinberg, Pablo and Fischer, Thomas M. and Kiulies, Sandra and Biefang, Katja and Platt, Karl-Ludwig and Oesch, Franz and B{\"o}ttger, Thomas and Bulitta, Clemens and Kempf, Peter and Hengstler, Jan Georg}, title = {Drug metabolizing capacity of cryopreserved human, rat and mouse liver parenchymal cells in suspension}, year = {1999}, language = {en} } @article{FranzToebbensLehmannetal.2020, author = {Franz, Alexandra and T{\"o}bbens, Daniel M. and Lehmann, Frederike and K{\"a}rgell, Martin and Schorr, Susan}, title = {The influence of deuteration on the crystal structure of hybrid halide perovskites: a temperature-dependent neutron diffraction study of FAPbBr(3)}, series = {Acta crystallographica; Section B, Structural science, crystal engineering and materials}, volume = {76}, journal = {Acta crystallographica; Section B, Structural science, crystal engineering and materials}, number = {2}, publisher = {Wiley-Blackwell}, address = {Oxford [u.a.]}, issn = {2052-5206}, doi = {10.1107/S2052520620002620}, pages = {267 -- 274}, year = {2020}, abstract = {This paper discusses the full structural solution of the hybrid perovskite formamidinium lead tribromide (FAPbBr(3)) and its temperature-dependent phase transitions in the range from 3 K to 300 K using neutron powder diffraction and synchrotron X-ray diffraction. Special emphasis is put on the influence of deuteration on formamidinium, its position in the unit cell and disordering in comparison to fully hydrogenated FAPbBr(3). The temperature-dependent measurements show that deuteration critically influences the crystal structures, i.e. results in partially-ordered temperature-dependent structural modifications in which two symmetry-independent molecule positions with additional dislocation of the molecular centre atom and molecular angle inclinations are present.}, language = {en} } @article{FranzToebbensSteckhanetal.2018, author = {Franz, Alexandra and T{\"o}bbens, Daniel M. and Steckhan, Julia and Schorr, Susan}, title = {Determination of the miscibility gap in the solid solutions series of methylammonium lead iodide/chloride}, series = {Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials}, volume = {74}, journal = {Acta Crystallographica Section B: Structural Science, Crystal Engineering and Materials}, publisher = {International Union of Crystallography}, address = {Chester}, issn = {2052-5206}, doi = {10.1107/S2052520618010764}, pages = {445 -- 449}, year = {2018}, abstract = {Perovskites are widely known for their enormous possibility of elemental substitution, which leads to a large variety of physical properties. Hybrid perovskites such as CH3NH3PbI3 (MAPbI(3)) and CH3NH3PbCl3 (MAPbCl(3)) are perovskites with an A([XII])B([VI)X(-)([II)(])structure, where A is an organic molecule, B is a lead(II) cation and X is a halide anion of iodine or chlorine. Whereas MAPbCl(3) crystallizes in the cubic space group Pm (3) over barm, MAPbI(3) is in the tetragonal space group I4/mcm. The substitution of I by Cl leads to an increased tolerance against humidity but is challenging or even impossible due to their large difference in ionic radii. Here, the influence of an increasing Cl content in the reaction solution on the miscibility of the solid solution members is examined systematically. Powders were synthesized by two different routes depending on the I:Cl ratio. High-resolution synchrotron X-ray data are used to establish values for the limits of the miscibility gap which are 3.1 (1.1) mol\% MAPbCl(3) in MAPI(3) and 1.0 (1) mol\% MAPbI(3) in MAPCl. The establishment of relations between average pseudo-cubic lattice parameters for both phases allows a determination of the degree of substitution from the observed lattice parameters.}, language = {en} } @article{LehmannFranzToebbensetal.2019, author = {Lehmann, Frederike and Franz, Alexandra and Toebbens, Daniel M. and Levcenco, Sergej and Unold, Thomas and Taubert, Andreas and Schorr, Susan}, title = {The phase diagram of a mixed halide (Br, I) hybrid perovskite obtained by synchrotron X-ray diffraction}, series = {RSC Advances}, volume = {9}, journal = {RSC Advances}, number = {20}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {2046-2069}, doi = {10.1039/c8ra09398a}, pages = {11151 -- 11159}, year = {2019}, abstract = {By using synchrotron X-ray powder diffraction, the temperature dependent phase diagram of the hybrid perovskite tri-halide compounds, methyl ammonium lead iodide (MAPbI3, MA+ = CH3NH3+) and methyl ammonium lead bromide (MAPbBr3), as well as of their solid solutions, has been established. The existence of a large miscibility gap between 0.29 ≤ x ≤ 0.92 (±0.02) for the MAPb(I1-xBrx)3 solid solution has been proven. A systematic study of the lattice parameters for the solid solution series at room temperature revealed distinct deviations from Vegard's law. Furthermore, temperature dependent measurements showed that a strong temperature dependency of lattice parameters from the composition is present for iodine rich compositions. In contrast, the bromine rich compositions show an unusually low dependency of the phase transition temperature from the degree of substitution.}, language = {en} } @article{BreitenbachRehfeldGoswamietal.2012, author = {Breitenbach, Sebastian Franz Martin and Rehfeld, Kira and Goswami, Bedartha and Baldini, James U. L. and Ridley, H. E. and Kennett, D. J. and Prufer, K. M. and Aquino, Valorie V. and Asmerom, Yemane and Polyak, V. J. and Cheng, Hai and Kurths, J{\"u}rgen and Marwan, Norbert}, title = {Constructing Proxy Records from Age models (COPRA)}, series = {Climate of the past : an interactive open access journal of the European Geosciences Union}, volume = {8}, journal = {Climate of the past : an interactive open access journal of the European Geosciences Union}, number = {5}, publisher = {Copernicus}, address = {G{\"o}ttingen}, issn = {1814-9324}, doi = {10.5194/cp-8-1765-2012}, pages = {1765 -- 1779}, year = {2012}, abstract = {Reliable age models are fundamental for any palaeoclimate reconstruction. Available interpolation procedures between age control points are often inadequately reported, and very few translate age uncertainties to proxy uncertainties. Most available modeling algorithms do not allow incorporation of layer counted intervals to improve the confidence limits of the age model in question. We present a framework that allows detection and interactive handling of age reversals and hiatuses, depth-age modeling, and proxy-record reconstruction. Monte Carlo simulation and a translation procedure are used to assign a precise time scale to climate proxies and to translate dating uncertainties to uncertainties in the proxy values. The presented framework allows integration of incremental relative dating information to improve the final age model. The free software package COPRA1.0 facilitates easy interactive usage.}, language = {en} } @article{LechleitnerBreitenbachRehfeldetal.2017, author = {Lechleitner, Franziska A. and Breitenbach, Sebastian Franz Martin and Rehfeld, Kira and Ridley, Harriet E. and Asmerom, Yemane and Prufer, Keith M. and Marwan, Norbert and Goswami, Bedartha and Kennett, Douglas J. and Aquino, Valorie V. and Polyak, Victor and Haug, Gerald H. and Eglinton, Timothy I. and Baldini, James U. L.}, title = {Tropical rainfall over the last two millennia: evidence for a low-latitude hydrologic seesaw}, series = {Scientific reports}, volume = {7}, journal = {Scientific reports}, publisher = {Nature Publ. Group}, address = {London}, issn = {2045-2322}, doi = {10.1038/srep45809}, pages = {9}, year = {2017}, abstract = {The presence of a low-to mid-latitude interhemispheric hydrologic seesaw is apparent over orbital and glacial-interglacial timescales, but its existence over the most recent past remains unclear. Here we investigate, based on climate proxy reconstructions from both hemispheres, the inter-hemispherical phasing of the Intertropical Convergence Zone (ITCZ) and the low-to mid-latitude teleconnections in the Northern Hemisphere over the past 2000 years. A clear feature is a persistent southward shift of the ITCZ during the Little Ice Age until the beginning of the 19th Century. Strong covariation between our new composite ITCZ-stack and North Atlantic Oscillation (NAO) records reveals a tight coupling between these two synoptic weather and climate phenomena over decadal-to-centennial timescales. This relationship becomes most apparent when comparing two precisely dated, high-resolution paleorainfall records from Belize and Scotland, indicating that the low-to mid-latitude teleconnection was also active over annual-decadal timescales. It is likely a combination of external forcing, i.e., solar and volcanic, and internal feedbacks, that drives the synchronous ITCZ and NAO shifts via energy flux perturbations in the tropics.}, language = {en} } @misc{RaafatMrochenAl’Sholuietal.2020, author = {Raafat, Dina and Mrochen, Daniel M. and Al'Sholui, Fawaz and Heuser, Elisa and Ryll, Ren{\´e} and Pritchett-Corning, Kathleen R. and Jacob, Jens and Walther, Bernd and Matuschka, Franz-Rainer and Richter, Dania}, title = {Molecular epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in wild, captive and laboratory rats}, series = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe}, journal = {Zweitver{\"o}ffentlichungen der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe}, number = {2}, issn = {1866-8364}, doi = {10.25932/publishup-51237}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-512379}, pages = {24}, year = {2020}, abstract = {Rats are a reservoir of human- and livestock-associated methicillin-resistant Staphylococcus aureus (MRSA). However, the composition of the natural S. aureus population in wild and laboratory rats is largely unknown. Here, 144 nasal S. aureus isolates from free-living wild rats, captive wild rats and laboratory rats were genotyped and profiled for antibiotic resistances and human-specific virulence genes. The nasal S. aureus carriage rate was higher among wild rats (23.4\%) than laboratory rats (12.3\%). Free-living wild rats were primarily colonized with isolates of clonal complex (CC) 49 and CC130 and maintained these strains even in husbandry. Moreover, upon livestock contact, CC398 isolates were acquired. In contrast, laboratory rats were colonized with many different S. aureus lineages—many of which are commonly found in humans. Five captive wild rats were colonized with CC398-MRSA. Moreover, a single CC30-MRSA and two CC130-MRSA were detected in free-living or captive wild rats. Rat-derived S. aureus isolates rarely harbored the phage-carried immune evasion gene cluster or superantigen genes, suggesting long-term adaptation to their host. Taken together, our study revealed a natural S. aureus population in wild rats, as well as a colonization pressure on wild and laboratory rats by exposure to livestock- and human-associated S. aureus, respectively.}, language = {en} } @article{RaafatMrochenAl’Sholuietal.2020, author = {Raafat, Dina and Mrochen, Daniel M. and Al'Sholui, Fawaz and Heuser, Elisa and Ryll, Ren{\´e} and Pritchett-Corning, Kathleen R. and Jacob, Jens and Walther, Bernd and Matuschka, Franz-Rainer and Richter, Dania}, title = {Molecular epidemiology of methicillin-susceptible and methicillin-resistant Staphylococcus aureus in wild, captive and laboratory rats}, series = {Toxins}, volume = {12}, journal = {Toxins}, number = {2}, publisher = {MDPI}, address = {Basel}, issn = {2072-6651}, doi = {10.3390/toxins12020080}, pages = {1 -- 22}, year = {2020}, abstract = {Rats are a reservoir of human- and livestock-associated methicillin-resistant Staphylococcus aureus (MRSA). However, the composition of the natural S. aureus population in wild and laboratory rats is largely unknown. Here, 144 nasal S. aureus isolates from free-living wild rats, captive wild rats and laboratory rats were genotyped and profiled for antibiotic resistances and human-specific virulence genes. The nasal S. aureus carriage rate was higher among wild rats (23.4\%) than laboratory rats (12.3\%). Free-living wild rats were primarily colonized with isolates of clonal complex (CC) 49 and CC130 and maintained these strains even in husbandry. Moreover, upon livestock contact, CC398 isolates were acquired. In contrast, laboratory rats were colonized with many different S. aureus lineages—many of which are commonly found in humans. Five captive wild rats were colonized with CC398-MRSA. Moreover, a single CC30-MRSA and two CC130-MRSA were detected in free-living or captive wild rats. Rat-derived S. aureus isolates rarely harbored the phage-carried immune evasion gene cluster or superantigen genes, suggesting long-term adaptation to their host. Taken together, our study revealed a natural S. aureus population in wild rats, as well as a colonization pressure on wild and laboratory rats by exposure to livestock- and human-associated S. aureus, respectively.}, language = {en} }