@article{SpringerBeyerDerrfussetal.2012, author = {Springer, Anne and Beyer, Juliane and Derrfuss, Jan and Volz, Kirsten G. and Hannover, Bettina}, title = {SEEING YOU OR THE SCENE? SELF-CONSTRUALS MODULATE INHIBITORY MECHANISMS OF ATTENTION}, series = {Social cognition : the journal of the International Social Cognition Network}, volume = {30}, journal = {Social cognition : the journal of the International Social Cognition Network}, number = {2}, publisher = {Guilford Press}, address = {New York}, issn = {0278-016X}, pages = {133 -- 152}, year = {2012}, abstract = {It has often been shown that independent self-construals (emphasizing personal uniqueness) coincide with an analytic, context-independent style of information processing whereas interdependent self-construals (emphasizing relatedness with others) promote holistic, context-dependent processing. The present study suggests that these cognitive variations between different self-construals can be accounted for by higher order cognitive functions for the control of ongoing mental operations (i.e., executive functions). Using an experimental paradigm, we showed naturalistic pictures displaying a face and a place superimposed on each other. On each trial, one of these dimensions served as a target (depicted in magenta), while the other served as a distractor (depicted in gray). The results showed that independency primed participants were less affected by distractors appearing in the presence of a target (i.e., smaller interference effect) than interdependency primed participants. Importantly, the independency primed participants revealed evidence of mental inhibition of distractors, showing longer reaction times when previously ignored distractors subsequently became targets (i.e., a negatively signed priming effect). Thus, our study is the first to suggest that differences in fundamental processes of cognitive control, namely, the inhibition of automatically triggered (but inappropriate) response tendencies, are the driving force behind the many previously reported differences between individuals primed for independency versus interdependency.}, language = {en} } @article{SieversRawelRingeletal.2016, author = {Sievers, Steven and Rawel, Harshadrai Manilal and Ringel, Karl Peter and Niggemann, Bodo and Beyer, Kirsten}, title = {Wheat protein recognition pattern in tolerant and allergic children}, series = {Pediatric Allergy and Immunology}, volume = {27}, journal = {Pediatric Allergy and Immunology}, publisher = {Wiley-Blackwell}, address = {Hoboken}, issn = {0905-6157}, doi = {10.1111/pai.12502}, pages = {147 -- 155}, year = {2016}, abstract = {BackgroundWheat is one of the most common food allergens in early childhood. In contrast to other food allergies, wheat-specific IgE correlates badly with clinical symptoms and relevant components have been identified mostly for wheat-depended exercise-induced anaphylaxis. Moreover, a high percentage of patients present with immediate type symptoms but wheat-specific IgE cannot be detected with commercial available systems. ObjectiveWe addressed the question whether the IgE recognition pattern between wheat allergic (WA) and clinically tolerant (WT) children differs in order to identify individual proteins useful for component-resolved diagnostics. MethodsSera of 106 children with suspected wheat allergy, of whom 44 children had clinical relevant wheat allergy and 62 were tolerant upon oral food challenge, were analyzed for wheat-specific IgE using the ImmunoCap system as well as immunoblots against water and salt soluble, and water-insoluble protein fractions. 40 randomly selected sera were analyzed for specific IgE to 5-gliadin. ResultsSixty-three percent of the WT and 86\% of the WA children were sensitized to wheat with >0.35 kU(A)/l in ImmunoCAP analysis. We could confirm the role of -, ss-, -, and -gliadins, and LMW glutenin subunits as major allergens and found also IgE binding to a broad spectrum of water- and salt-soluble protein bands. It is of great importance that wheat allergic and tolerant patients showed IgE binding to the same protein bands. WT and WA did not significantly differ in levels of 5-gliadin-specific IgE. Conclusions \& Clinical RelevanceChildren with challenge proven clinical relevant food allergy and tolerant ones had a similar spectrum of IgE binding to the same protein bands. These findings imply that component-resolved diagnostics might not be helpful in the diagnostic work-up of wheat allergy.}, language = {en} }