@article{AbdallaAharonianBenkhalietal.2018,
  author    = {Abdalla, Hassan E. and Aharonian, Felix A. and Benkhali, F. Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arakawa, M. and Arcaro, C. and Armand, C. and Arrieta, M. and Backes, M. and Barnard, M. and Becherini, Y. and Tjus, J. Becker and Berge, D. and Bernhard, S. and Bernlohr, K. and Blackwell, R. and Bottcher, M. and Boisson, C. and Bolmont, J. and Bonnefoy, S. and Bordas, Pol and Bregeon, J. and Brun, F. and Brun, P. and Bryan, M. and Buechele, M. and Bulik, T. and Bylund, T. and Capasso, M. and Caroff, S. and Carosi, A. and Casanova, Sabrina and Cerruti, M. and Chakraborty, N. and Chandra, S. and Chen, A. and Colafrancesco, S. and Condon, B. and Davids, I. D. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Dmytriiev, A. and Donath, A. and Doroshenko, V and Dyks, J. and Egberts, Kathrin and Emery, G. and Ernenwein, J-P and Eschbach, S. and Fegan, S. and Fiasson, A. and Fontaine, G. and Funk, S. and Fuessling, M. and Gabici, S. and Gallant, Y. A. and Gate, F. and Giavitto, G. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M-H and Hahn, J. and Haupt, M. and Heinzelmann, G. and Henri, G. and Hermann, G. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horns, D. and Huber, D. and Iwasaki, H. and Jacholkowska, A. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jouvin, L. and Jung-Richardt, I and Kastendieck, M. A. and Katarzynski, K. and Katsuragawa, M. and Katz, U. and Kerszberg, D. and Khangulyan, D. and Khelifi, B. and King, J. and Klepser, S. and Kluzniak, W. and Komin, Nu and Kosack, K. and Krakau, S. and Kraus, M. and Kr{\"u}ger, P. P. and Lamanna, G. and Lau, J. and Lefaucheur, J. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J-P and Leser, Eva and Lohse, T. and Lorentz, M. and Lopez-Coto, R. and Lypova, I and Malyshev, D. and Marandon, V and Marcowith, Alexandre and Mariaud, C. and Marti-Devesa, G. and Marx, R. and Maurin, G. and Meintjes, P. J. and Mitchell, A. M. W. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Moulin, Emmanuel and Murach, T. and Nakashima, S. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and Odaka, H. and Ohm, S. and Ostrowski, M. and Oya, I and Padovani, M. and Panter, M. and Parsons, R. D. and Perennes, C. and Petrucci, P-O and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V and Noel, A. Priyana and Prokhorov, D. A. and Prokoph, H. and Puehlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reimer, A. and Reimer, O. and Renaud, M. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Ruiz-Velasco, E. and Sahakian, V and Saito, S. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Schlickeiser, R. and Schussler, F. and Schulz, A. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Senniappan, M. and Seyffert, A. S. and Shafi, N. and Shilon, I and Shiningayamwe, K. and Simoni, R. and Sinha, A. and Sol, H. and Spanier, F. and Specovius, A. and Spir-Jacob, M. and Stawarz, L. and Steenkamp, R. and Stegmann, Christian and Steppa, Constantin Beverly and Takahashi, T. and Tavernet, J-P and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tibaldo, L. and Tiziani, D. and Tluczykont, M. and Trichard, C. and Tsirou, M. and Tsuji, N. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Vincent, P. and Vink, J. and Voisin, F. and Voelk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Wagner, R. M. and White, R. and Wierzcholska, A. and Yang, R. and Zaborov, D. and Zacharias, M. and Zanin, R. and Zdziarski, A. A. and Zech, Alraune and Zefi, F. and Ziegler, A. and Zorn, J. and Zywucka, N. and Kerr, M. and Johnston, S. and Shannon, R. M.},
  title     = {First ground-based measurement of sub-20 GeV to 100 GeV gamma-Rays from the Vela pulsar with HESS II},
  series = {Astronomy and astrophysics : an international weekly journal},
  volume    = {620},
  journal   = {Astronomy and astrophysics : an international weekly journal},
  publisher = {EDP Sciences},
  address   = {Les Ulis},
  organization    = {HESS Collaboration},
  issn      = {1432-0746},
  doi       = {10.1051/0004-6361/201732153},
  pages     = {14},
  year      = {2018},
  abstract  = {Aims. We report on the measurement and investigation of pulsed high-energy y-ray emission from the Vela pulsar, PSR B0833-45, based on observations with the largest telescope of H.E.S.S., CT5, in monoscopic mode, and on data obtained with the Fermi-LAT. Methods. Data from 40.3 h of observations carried out with the H.E.S.S. II array from 2013 to 2015 have been used. A dedicated very low-threshold event reconstruction and analysis pipeline was developed to achieve the lowest possible energy threshold. Eight years of Fermi-LAT data were analysed and also used as reference to validate the CT5 telescope response model and analysis methods. Results. A pulsed gamma-ray signal at a significance level of more than 15 sigma is detected from the P2 peak of the Vela pulsar light curve. Of a total of 15 835 events, more than 6000 lie at an energy below 20 GeV, implying a significant overlap between H.E.S.S. II-CT5 and the Fermi-LAT. While the investigation of the pulsar light curve with the LAT confirms characteristics previously known up to 20 GeV in the tens of GeV energy range, CT5 data show a change in the pulse morphology of P2, i.e. an extreme sharpening of its trailing edge, together with the possible onset of a new component at 3.4 sigma significance level. Assuming a power-law model for the P2 spectrum, an excellent agreement is found for the photon indices (Gamma similar or equal to 4.1) obtained with the two telescopes above 10 GeV and an upper bound of 8\% is derived on the relative offset between their energy scales. Using data from both instruments, it is shown however that the spectrum of P2 in the 10-100 GeV has a pronounced curvature; this is a confirmation of the sub-exponential cut-off form found at lower energies with the LAT. This is further supported by weak evidence of an emission above 100 GeV obtained with CT5. In contrast, converging indications are found from both CT5 and LAT data for the emergence of a hard component above 50 GeV in the leading wing (LW2) of P2, which possibly extends beyond 100 GeV. Conclusions. The detection demonstrates the performance and understanding of CT5 from 100 GeV down to the sub-20 GeV domain, i.e. unprecedented low energy for ground-based gamma-ray astronomy. The extreme sharpening of the trailing edge of the P2 peak found in the H.E.S.S. II light curve of the Vela pulsar and the possible extension beyond 100 GeV of at least one of its features, LW2, provide further constraints to models of gamma-Ray emission from pulsars.},
  language  = {en}
}
@article{AckermannAjelloAllafortetal.2011,
  author    = {Ackermann, Margit and Ajello, M. and Allafort, A. J. and Baldini, L. and Ballet, J. and Barbiellini, G. and Bastieri, D. and Belfiore, A. and Bellazzini, R. and Berenji, B. and Blandford, R. D. and Bloom, E. D. and Bonamente, E. and Borgland, A. W. and Bottacini, E. and Brigida, M. and Bruel, P. and Buehler, R. and Buson, S. and Caliandro, G. A. and Cameron, R. A. and Caraveo, P. A. and Casandjian, J. M. and Cecchi, C. and Chekhtman, A. and Cheung, C. C. and Chiang, J. and Ciprini, S. and Claus, R. and Cohen-Tanugi, J. and de Angelis, A. and de Palma, F. and Dermer, C. D. and do Couto e Silva, E. and Drell, P. S. and Dumora, D. and Favuzzi, C. and Fegan, S. J. and Focke, W. B. and Fortin, P. and Fukazawa, Y. and Fusco, P. and Gargano, F. and Germani, S. and Giglietto, N. and Giordano, F. and Giroletti, M. and Glanzman, T. and Godfrey, G. and Grenier, I. A. and Guillemot, L. and Guiriec, S. and Hadasch, D. and Hanabata, Y. and Harding, A. K. and Hayashida, M. and Hayashi, K. and Hays, E. and Johannesson, G. and Johnson, A. S. and Kamae, T. and Katagiri, H. and Kataoka, J. and Kerr, M. and Knoedlseder, J. and Kuss, M. and Lande, J. and Latronico, L. and Lee, S. -H. and Longo, F. and Loparco, F. and Lott, B. and Lovellette, M. N. and Lubrano, P. and Martin, P. and Mazziotta, Mario Nicola and McEnery, J. E. and Mehault, J. and Michelson, P. F. and Mitthumsiri, W. and Mizuno, T. and Monte, C. and Monzani, M. E. and Morselli, A. and Moskalenko, I. V. and Murgia, S. and Naumann-Godo, M. and Nolan, P. L. and Norris, J. P. and Nuss, E. and Ohsugi, T. and Okumura, A. and Orlando, E. and Ormes, J. F. and Ozaki, M. and Paneque, D. and Parent, D. and Pesce-Rollins, M. and Pierbattista, M. and Piron, F. and Pohl, Martin and Prokhorov, D. and Raino, S. and Rando, R. and Razzano, M. and Reposeur, T. and Ritz, S. and Parkinson, P. M. Saz and Sgro, C. and Siskind, E. J. and Smith, P. D. and Spinelli, P. and Strong, A. W. and Takahashi, H. and Tanaka, T. and Thayer, J. G. and Thayer, J. B. and Thompson, D. J. and Tibaldo, L. and Torres, D. F. and Tosti, G. and Tramacere, A. and Troja, E. and Uchiyama, Y. and Vandenbroucke, J. and Vasileiou, V. and Vianello, G. and Vitale, V. and Waite, A. P. and Wang, P. and Winer, B. L. and Wood, K. S. and Yang, Z. and Zimmer, S. and Bontemps, S.},
  title     = {A cocoon of freshly accelerated cosmic rays detected by fermi in the cygnus superbubble},
  series = {Science},
  volume    = {334},
  journal   = {Science},
  number    = {6059},
  publisher = {American Assoc. for the Advancement of Science},
  address   = {Washington},
  issn      = {0036-8075},
  doi       = {10.1126/science.1210311},
  pages     = {1103 -- 1107},
  year      = {2011},
  abstract  = {The origin of Galactic cosmic rays is a century-long puzzle. Indirect evidence points to their acceleration by supernova shockwaves, but we know little of their escape from the shock and their evolution through the turbulent medium surrounding massive stars. Gamma rays can probe their spreading through the ambient gas and radiation fields. The Fermi Large Area Telescope (LAT) has observed the star-forming region of Cygnus X. The 1- to 100-gigaelectronvolt images reveal a 50-parsec-wide cocoon of freshly accelerated cosmic rays that flood the cavities carved by the stellar winds and ionization fronts from young stellar clusters. It provides an example to study the youth of cosmic rays in a superbubble environment before they merge into the older Galactic population.},
  language  = {en}
}
@article{AbdoAckermannAjelloetal.2011,
  author    = {Abdo, A. A. and Ackermann, Margit and Ajello, M. and Allafort, A. J. and Baldini, L. and Ballet, J. and Barbiellini, G. and Baring, M. G. and Bastieri, D. and Bellazzini, R. and Berenji, B. and Blandford, R. D. and Bloom, E. D. and Bonamente, E. and Borgland, A. W. and Bouvier, A. and Brandt, T. J. and Bregeon, Johan and Brigida, M. and Bruel, P. and Buehler, R. and Buson, S. and Caliandro, G. A. and Cameron, R. A. and Caraveo, P. A. and Casandjian, J. M. and Cecchi, C. and Chaty, S. and Chekhtman, A. and Cheung, C. C. and Chiang, J. and Cillis, A. N. and Ciprini, S. and Claus, R. and Cohen-Tanugi, J. and Conrad, Jan and Corbel, S. and Cutini, S. and de Angelis, A. and de Palma, F. and Dermer, C. D. and Digel, S. W. and do Couto e Silva, E. and Drell, P. S. and Drlica-Wagner, A. and Dubois, R. and Dumora, D. and Favuzzi, C. and Ferrara, E. C. and Fortin, P. and Frailis, M. and Fukazawa, Y. and Fukui, Y. and Funk, S. and Fusco, P. and Gargano, F. and Gasparrini, D. and Gehrels, N. and Germani, S. and Giglietto, N. and Giordano, F. and Giroletti, M. and Glanzman, T. and Godfrey, G. and Grenier, I. A. and Grondin, M. -H. and Guiriec, S. and Hadasch, D. and Hanabata, Y. and Harding, A. K. and Hayashida, M. and Hayashi, K. and Hays, E. and Horan, D. and Jackson, M. S. and Johannesson, G. and Johnson, A. S. and Kamae, T. and Katagiri, H. and Kataoka, J. and Kerr, M. and Knoedlseder, J. and Kuss, M. and Lande, J. and Latronico, L. and Lee, S. -H. and Lemoine-Goumard, M. and Longo, F. and Loparco, F. and Lovellette, M. N. and Lubrano, P. and Madejski, G. M. and Makeev, A. and Mazziotta, Mario Nicola and McEnery, J. E. and Michelson, P. F. and Mignani, R. P. and Mitthumsiri, W. and Mizuno, T. and Moiseev, A. A. and Monte, C. and Monzani, M. E. and Morselli, A. and Moskalenko, I. V. and Murgia, S. and Naumann-Godo, M. and Nolan, P. L. and Norris, J. P. and Nuss, E. and Ohsugi, T. and Okumura, A. and Orlando, E. and Ormes, J. F. and Paneque, D. and Parent, D. and Pelassa, V. and Pesce-Rollins, M. and Pierbattista, M. and Piron, F. and Pohl, Martin and Porter, T. A. and Raino, S. and Rando, R. and Razzano, M. and Reimer, O. and Reposeur, T. and Ritz, S. and Romani, R. W. and Roth, M. and Sadrozinski, H. F. -W. and Parkinson, P. M. Saz and Sgro, C. and Smith, D. A. and Smith, P. D. and Spandre, G. and Spinelli, P. and Strickman, M. S. and Tajima, H. and Takahashi, H. and Takahashi, T. and Tanaka, T. and Thayer, J. G. and Thayer, J. B. and Thompson, D. J. and Tibaldo, L. and Tibolla, O. and Torres, D. F. and Tosti, G. and Tramacere, A. and Troja, E. and Uchiyama, Y. and Vandenbroucke, J. and Vasileiou, V. and Vianello, G. and Vilchez, N. and Vitale, V. and Waite, A. P. and Wang, P. and Winer, B. L. and Wood, K. S. and Yamamoto, H. and Yamazaki, R. and Yang, Z. and Ziegler, M.},
  title     = {Observations of the young supernova remnant RX J1713.7-3946 with the fermi large area telescope},
  series = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
  volume    = {734},
  journal   = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
  number    = {1},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {0004-637X},
  doi       = {10.1088/0004-637X/734/1/28},
  pages     = {9},
  year      = {2011},
  abstract  = {We present observations of the young supernova remnant (SNR) RX J1713.7-3946 with the Fermi Large Area Telescope (LAT). We clearly detect a source positionally coincident with the SNR. The source is extended with a best-fit extension of 0 degrees.55 +/- 0 degrees.04 matching the size of the non-thermal X-ray and TeV gamma-ray emission from the remnant. The positional coincidence and the matching extended emission allow us to identify the LAT source with SNR RX J1713.7-3946. The spectrum of the source can be described by a very hard power law with a photon index of Gamma = 1.5 +/- 0.1 that coincides in normalization with the steeper H. E. S. S.-detected gamma-ray spectrum at higher energies. The broadband gamma-ray emission is consistent with a leptonic origin as the dominant mechanism for the gamma-ray emission.},
  language  = {en}
}
@article{WuttkeLiLietal.2019,
  author    = {Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B. and Feitosa, Mary F. and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y. and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O. and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and Van der Most, Peter J. and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer Singh and Almgren, Peter and Amin, Najaf and Arnlov, Johan and Bakker, Stephan J. L. and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L. and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and B{\"o}ttinger, Erwin and Boutin, Thibaud S. and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S. and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickael and Carroll, Robert J. and Catamo, Eulalia and Chambers, John C. and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P. and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and De Borst, Martin H. and De Grandi, Alessandro and De Mutsert, Renee and De Vries, Aiko P. J. and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K. and Felix, Janine F. and Foo, Valencia Hui Xian and Franco, Oscar H. and Franke, Andre and Freedman, Barry I. and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T. and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and Girotto, Giorgia and Giulianini, Franco and Gogele, Martin and Gordon, Scott D. and Gudbjartsson, Daniel F. and Gudnason, Vilmundur and Haller, Toomas and Hamet, Pavel and Harris, Tamara B. and Hartman, Catharina A. and Hayward, Caroline and Hellwege, Jacklyn N. and Heng, Chew-Kiat and Hicks, Andrew A. and Hofer, Edith and Huang, Wei and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Indridason, Olafur S. and Ingelsson, Erik and Ising, Marcus and Jaddoe, Vincent W. V. and Jakobsdottir, Johanna and Jonas, Jost B. and Joshi, Peter K. and Josyula, Navya Shilpa and Jung, Bettina and Kahonen, Mika and Kamatani, Yoichiro and Kammerer, Candace M. and Kanai, Masahiro and Kastarinen, Mika and Kerr, Shona M. and Khor, Chiea-Chuen and Kiess, Wieland and Kleber, Marcus E. and Koenig, Wolfgang and Kooner, Jaspal S. and Korner, Antje and Kovacs, Peter and Kraja, Aldi T. and Krajcoviechova, Alena and Kramer, Holly and Kramer, Bernhard K. and Kronenberg, Florian and Kubo, Michiaki and Kuhnel, Brigitte and Kuokkanen, Mikko and Kuusisto, Johanna and La Bianca, Martina and Laakso, Markku and Lange, Leslie A. and Langefeld, Carl D. and Lee, Jeannette Jen-Mai and Lehne, Benjamin and Lehtimaki, Terho and Lieb, Wolfgang and Lim, Su-Chi and Lind, Lars and Lindgren, Cecilia M. and Liu, Jun and Liu, Jianjun and Loeffler, Markus and Loos, Ruth J. F. and Lucae, Susanne and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Magi, Reedik and Magnusson, Patrik K. E. and Mahajan, Anubha and Martin, Nicholas G. and Martins, Jade and Marz, Winfried and Mascalzoni, Deborah and Matsuda, Koichi and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Metspalu, Andres and Mikaelsdottir, Evgenia K. and Milaneschi, Yuri and Miliku, Kozeta and Mishra, Pashupati P. and Program, V. A. Million Veteran and Mohlke, Karen L. and Mononen, Nina and Montgomery, Grant W. and Mook-Kanamori, Dennis O. and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nalls, Mike A. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and Noordam, Raymond and Olafsson, Isleifur and Oldehinkel, Albertine J. and Orho-Melander, Marju and Ouwehand, Willem H. and Padmanabhan, Sandosh and Palmer, Nicholette D. and Palsson, Runolfur and Penninx, Brenda W. J. H. and Perls, Thomas and Perola, Markus and Pirastu, Mario and Pirastu, Nicola and Pistis, Giorgio and Podgornaia, Anna I. and Polasek, Ozren and Ponte, Belen and Porteous, David J. and Poulain, Tanja and Pramstaller, Peter P. and Preuss, Michael H. and Prins, Bram P. and Province, Michael A. and Rabelink, Ton J. and Raffield, Laura M. and Raitakari, Olli T. and Reilly, Dermot F. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Ridker, Paul M. and Rivadeneira, Fernando and Rizzi, Federica and Roberts, David J. and Robino, Antonietta and Rossing, Peter and Rudan, Igor and Rueedi, Rico and Ruggiero, Daniela and Ryan, Kathleen A. and Saba, Yasaman and Sabanayagam, Charumathi and Salomaa, Veikko and Salvi, Erika and Saum, Kai-Uwe and Schmidt, Helena and Schmidt, Reinhold and Ben Schottker, and Schulz, Christina-Alexandra and Schupf, Nicole and Shaffer, Christian M. and Shi, Yuan and Smith, Albert V. and Smith, Blair H. and Soranzo, Nicole and Spracklen, Cassandra N. and Strauch, Konstantin and Stringham, Heather M. and Stumvoll, Michael and Svensson, Per O. and Szymczak, Silke and Tai, E-Shyong and Tajuddin, Salman M. and Tan, Nicholas Y. Q. and Taylor, Kent D. and Teren, Andrej and Tham, Yih-Chung and Thiery, Joachim and Thio, Chris H. L. and Thomsen, Hauke and Thorleifsson, Gudmar and Toniolo, Daniela and Tonjes, Anke and Tremblay, Johanne and Tzoulaki, Ioanna and Uitterlinden, Andre G. and Vaccargiu, Simona and Van Dam, Rob M. and Van der Harst, Pim and Van Duijn, Cornelia M. and Edward, Digna R. Velez and Verweij, Niek and Vogelezang, Suzanne and Volker, Uwe and Vollenweider, Peter and Waeber, Gerard and Waldenberger, Melanie and Wallentin, Lars and Wang, Ya Xing and Wang, Chaolong and Waterworth, Dawn M. and Bin Wei, Wen and White, Harvey and Whitfield, John B. and Wild, Sarah H. and Wilson, James F. and Wojczynski, Mary K. and Wong, Charlene and Wong, Tien-Yin and Xu, Liang and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Weihua and Zonderman, Alan B. and Rotter, Jerome I. and Bochud, Murielle and Psaty, Bruce M. and Vitart, Veronique and Wilson, James G. and Dehghan, Abbas and Parsa, Afshin and Chasman, Daniel I. and Ho, Kevin and Morris, Andrew P. and Devuyst, Olivier and Akilesh, Shreeram and Pendergrass, Sarah A. and Sim, Xueling and Boger, Carsten A. and Okada, Yukinori and Edwards, Todd L. and Snieder, Harold and Stefansson, Kari and Hung, Adriana M. and Heid, Iris M. and Scholz, Markus and Teumer, Alexander and Kottgen, Anna and Pattaro, Cristian},
  title     = {A catalog of genetic loci associated with kidney function from analyses of a million individuals},
  series = {Nature genetics},
  volume    = {51},
  journal   = {Nature genetics},
  number    = {6},
  publisher = {Nature Publ. Group},
  address   = {New York},
  organization    = {Lifelines COHort Study},
  issn      = {1061-4036},
  doi       = {10.1038/s41588-019-0407-x},
  pages     = {957 -- +},
  year      = {2019},
  abstract  = {Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.},
  language  = {en}
}
@article{AliuArchambaultArlenetal.2012,
  author    = {Aliu, E. and Archambault, S. and Arlen, T. and Aune, T. and Beilicke, M. and Benbow, W. and Boettcher, Markus and Bouvier, A. and Bugaev, V. and Cannon, A. and Cesarini, A. and Ciupik, L. and Collins-Hughes, E. and Connolly, M. P. and Cui, W. and Dickherber, R. and Dumm, J. and Errando, M. and Falcone, A. and Federici, Stefania and Feng, Q. and Finley, J. P. and Finnegan, G. and Fortson, L. and Furniss, A. and Galante, N. and Gall, D. and Godambe, S. and Griffin, S. and Grube, J. and Gyuk, G. and Hanna, D. and Holder, J. and Huan, H. and Hughes, G. and Hui, C. M. and Imran, A. and Jameil, O. and Kaaret, P. and Karlsson, N. and Kertzman, M. and Kerr, J. and Khassen, Y. and Kieda, D. and Krawczynski, H. and Krennrich, F. and Lang, M. J. and Lee, K. and Madhavan, A. S. and Majumdar, P. and McArthur, S. and McCann, A. and Moriarty, P. and Mukherjee, R. and Nelson, T. and de Bhroithe, A. O'Faolain and Ong, R. A. and Orr, M. and Otte, A. N. and Park, N. and Perkins, J. S. and Pichel, A. and Pohl, Martin and Quinn, J. and Ragan, K. and Reynolds, P. T. and Roache, E. and Ruppel, J. and Saxon, D. B. and Schroedter, M. and Sembroski, G. H. and Sentuerk, G. D. and Smith, A. W. and Staszak, D. and Stroh, M. and Telezhinsky, Igor O. and Tesic, G. and Theiling, M. and Thibadeau, S. and Tsurusaki, K. and Varlotta, A. and Vassiliev, V. V. and Vivier, M. and Wakely, S. P. and Ward, J. E. and Weinstein, A. and Welsing, R. and Williams, D. A. and Zitzer, B.},
  title     = {Multiwavelength observations of the AGN 1ES 0414+009 with veritas, FERMI-LAT, SWIFT-XRT, AND MDM},
  series = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
  volume    = {755},
  journal   = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
  number    = {2},
  publisher = {IOP Publ. Ltd.},
  address   = {Bristol},
  issn      = {0004-637X},
  doi       = {10.1088/0004-637X/755/2/118},
  pages     = {7},
  year      = {2012},
  abstract  = {We present observations of the BL Lac object 1ES 0414+009 in the >200 GeV gamma-ray band by the VERITAS array of Cherenkov telescopes. 1ES 0414+009 was observed by VERITAS between 2008 January and 2011 February, resulting in 56.2 hr of good quality pointed observations. These observations resulted in a detection of 822 events from the source corresponding to a statistical significance of 6.4 standard deviations (6.4 sigma) above the background. The source flux, showing no evidence for variability, is measured as (5.2 +/- 1.1(stat) +/- 2.6(sys)) x 10(-12) photons cm(-2) s(-1) above 200 GeV, equivalent to approximately 2\% of the Crab Nebula flux above this energy. The differential photon spectrum from 230 GeV to 850 GeV is well fit by a power law with a photon index of Gamma = 3.4 +/- 0.5(stat) +/- 0.3(sys) and a flux normalization of (1.6 +/- 0.3(stat) +/- 0.8(sys)) x 10(-11) photons cm(-2) s(-1) at 300 GeV. We also present multiwavelength results taken in the optical (MDM), x-ray (Swift-XRT), and GeV (Fermi-LAT) bands and use these results to construct a broadband spectral energy distribution (SED). Modeling of this SED indicates that homogenous one-zone leptonic scenarios are not adequate to describe emission from the system, with a lepto-hadronic model providing a better fit to the data.},
  language  = {en}
}