@article{RobertGrunewaldSaueretal.2015, author = {Robert, Helene S. and Grunewald, Wim and Sauer, Michael and Cannoot, Bernard and Soriano, Mercedes and Swarup, Ranjan and Weijers, Dolf and Bennett, Malcolm and Boutilier, Kim and Friml, Jiri}, title = {Plant embryogenesis requires AUX/LAX-mediated auxin influx}, series = {Development : Company of Biologists}, volume = {142}, journal = {Development : Company of Biologists}, number = {4}, publisher = {Company of Biologists Limited}, address = {Cambridge}, issn = {0950-1991}, doi = {10.1242/dev.115832}, pages = {702 -- 711}, year = {2015}, abstract = {The plant hormone auxin and its directional transport are known to play a crucial role in defining the embryonic axis and subsequent development of the body plan. Although the role of PIN auxin efflux transporters has been clearly assigned during embryonic shoot and root specification, the role of the auxin influx carriers AUX1 and LIKE-AUX1 (LAX) proteins is not well established. Here, we used chemical and genetic tools on Brassica napus microspore-derived embryos and Arabidopsis thaliana zygotic embryos, and demonstrate that AUX1, LAX1 and LAX2 are required for both shoot and root pole formation, in concert with PIN efflux carriers. Furthermore, we uncovered a positive-feedback loop between MONOPTEROS-(ARF5)dependent auxin signalling and auxin transport. This MONOPTEROS dependent transcriptional regulation of auxin influx (AUX1, LAX1 and LAX2) and auxin efflux (PIN1 and PIN4) carriers by MONOPTEROS helps to maintain proper auxin transport to the root tip. These results indicate that auxin-dependent cell specification during embryo development requires balanced auxin transport involving both influx and efflux mechanisms, and that this transport is maintained by a positive transcriptional feedback on auxin signalling.}, language = {en} } @article{HerbertHerbertPollatosetal.2010, author = {Herbert, Beate M. and Herbert, Cornelia and Pollatos, Olga and Weimer, Katja and Sauer, Helene and Enck, Paul and Zipfel, Stephan}, title = {Effects of short-term food deprivation on interoceptive awareness, feelings and autonomic cardiac activity : implications for eating disorders}, issn = {0048-5772}, doi = {10.1111/j.1469-8986.2010.01111.x}, year = {2010}, abstract = {Poster session abstracts. Poster 9}, language = {en} } @article{HerbertHerbertPollatosetal.2012, author = {Herbert, Beate M. and Herbert, Cornelia and Pollatos, Olga and Weimer, Katja and Enck, Paul and Sauer, Helene and Zipfel, Stephan}, title = {Effects of short-term food deprivation on interoceptive awareness, feelings and autonomic cardiac activity}, series = {Biological psychology}, volume = {89}, journal = {Biological psychology}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0301-0511}, doi = {10.1016/j.biopsycho.2011.09.004}, pages = {71 -- 79}, year = {2012}, abstract = {The perception of internal bodily signals (interoception) plays a relevant role for emotion processing and feelings. This study investigated changes of interoceptive awareness and cardiac autonomic activity induced by short-term food deprivation and its relationship to hunger and affective experience. 20 healthy women were exposed to 24 h of food deprivation in a controlled setting. Interoceptive awareness was assessed by using a heartbeat tracking task. Felt hunger, cardiac autonomic activity, mood and subjective appraisal of interoceptive sensations were assessed before and after fasting. Results show that short-term fasting intensifies interoceptive awareness, not restricted to food cues, via changes of autonomic cardiac and/or cardiodynamic activity. The increase of interoceptive awareness was positively related to felt hunger. Additionally, the results demonstrate the role of cardiac vagal activity as a potential index of emotion related self-regulation, for hunger, mood and the affective appraisal of interoceptive signals during acute fasting.}, language = {en} }