@book{SchmidtWagnerSchwerdtfegeretal.2022, author = {Schmidt, Thorsten Ingo and Wagner, Dieter and Schwerdtfeger, Roswitha and Sch{\"a}fer, Andrea and Musil, Andreas and Edeling, Thomas and Bauer, Hartmut and Kinyakin, Andrey and Loladze, Besik and Nehls, Danny and Maaß, Christian and Kuhlmann, Sabine and Kuckei, Daniel A. and Hein, Victoria and Wille, Robert and Franzke, Jochen and B{\"u}chner, Christiane}, title = {Festschrift f{\"u}r Dr. Christiane B{\"u}chner in W{\"u}rdigung ihres Wirkens am Kommunalwissenschaftlichen Institut (1994-2022)}, series = {KWI Schriften}, journal = {KWI Schriften}, number = {13}, editor = {Franzke, Jochen}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-529-3}, issn = {1867-951X}, doi = {10.25932/publishup-54498}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-544987}, publisher = {Universit{\"a}t Potsdam}, pages = {125}, year = {2022}, abstract = {Diese eher ungew{\"o}hnliche, aber sehr pers{\"o}nlich gehaltene Festschrift ist dem lang­j{\"a}hrigen Wirken von Dr. Christiane B{\"u}chner als „Gesch{\"a}ftsf{\"u}hrerin" am Kommunal­wissenschaftlichen Institut (KWI) der Universit{\"a}t Potsdam gewidmet. Die von Prof. Jochen Franzke zusammengestellte und herausgegebene Publikation enth{\"a}lt im ersten Teil neben dem Grußwort des Gesch{\"a}ftsf{\"u}hrenden Direktors des KWI Herrn Prof. Thorsten Ingo Schmidt eine Reihe pers{\"o}nlicher W{\"u}rdigungen von Kolleginnen und Kollegen, Gastwissenschaftlern und Mitarbeitenden, die seit 1994 in verschiedenen Phasen der Entwicklung des KWIs mit Dr. Christiane B{\"u}chner eng zusammengearbeitet haben. Der abschließende Dokumentationsteil der Publikation enth{\"a}lt neben Ausz{\"u}gen aus dem Schriftenverzeichnis von Dr. Christiane B{\"u}chner auch zwei Nachdrucke aus deren Feder zum Thema der Kreisgebietsreform in Brandenburg (von 2001) sowie {\"u}ber den Landkreis Barnim (von 2019).}, language = {de} } @article{TockhornSutterCruzBournazouetal.2022, author = {Tockhorn, Philipp and Sutter, Johannes and Cruz Bournazou, Alexandros and Wagner, Philipp and J{\"a}ger, Klaus and Yoo, Danbi and Lang, Felix and Grischek, Max and Li, Bor and Li, Jinzhao and Shargaieva, Oleksandra and Unger, Eva and Al-Ashouri, Amran and K{\"o}hnen, Eike and Stolterfoht, Martin and Neher, Dieter and Schlatmann, Rutger and Rech, Bernd and Stannowski, Bernd and Albrecht, Steve and Becker, Christiane}, title = {Nano-optical designs for high-efficiency monolithic perovskite-silicon tandem solar cells}, series = {Nature nanotechnology}, volume = {17}, journal = {Nature nanotechnology}, number = {11}, publisher = {Nature Publishing Group}, address = {London [u.a.]}, issn = {1748-3387}, doi = {10.1038/s41565-022-01228-8}, pages = {1214 -- 1221}, year = {2022}, abstract = {Designing gentle sinusoidal nanotextures enables the realization of high-efficiency perovskite-silicon solar cells
Perovskite-silicon tandem solar cells offer the possibility of overcoming the power conversion efficiency limit of conventional silicon solar cells. Various textured tandem devices have been presented aiming at improved optical performance, but optimizing film growth on surface-textured wafers remains challenging. Here we present perovskite-silicon tandem solar cells with periodic nanotextures that offer various advantages without compromising the material quality of solution-processed perovskite layers. We show a reduction in reflection losses in comparison to planar tandems, with the new devices being less sensitive to deviations from optimum layer thicknesses. The nanotextures also enable a greatly increased fabrication yield from 50\% to 95\%. Moreover, the open-circuit voltage is improved by 15 mV due to the enhanced optoelectronic properties of the perovskite top cell. Our optically advanced rear reflector with a dielectric buffer layer results in reduced parasitic absorption at near-infrared wavelengths. As a result, we demonstrate a certified power conversion efficiency of 29.80\%.}, language = {en} } @article{PeterWenderingSchlickeiseretal.2022, author = {Peter, Lena and Wendering, D{\´e}sir{\´e}e Jacqueline and Schlickeiser, Stephan and Hoffmann, Henrike and Noster, Rebecca and Wagner, Dimitrios Laurin and Zarrinrad, Ghazaleh and M{\"u}nch, Sandra and Picht, Samira and Schulenberg, Sarah and Moradian, Hanieh and Mashreghi, Mir-Farzin and Klein, Oliver and Gossen, Manfred and Roch, Toralf and Babel, Nina and Reinke, Petra and Volk, Hans-Dieter and Amini, Leila and Schmueck-Henneresse, Michael}, title = {Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients}, series = {Molecular therapy methods and clinical development}, volume = {25}, journal = {Molecular therapy methods and clinical development}, publisher = {Cell Press}, address = {Cambridge}, issn = {2329-0501}, doi = {10.1016/j.omtm.2022.02.012}, pages = {52 -- 73}, year = {2022}, abstract = {Solid organ transplant (SOT) recipients receive therapeutic immunosuppression that compromises their immune response to infections and vaccines. For this reason, SOT patients have a high risk of developing severe coronavirus disease 2019 (COVID-19) and an increased risk of death from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Moreover, the efficiency of immunotherapies and vaccines is reduced due to the constant immunosuppression in this patient group. Here, we propose adoptive transfer of SARS-CoV-2-specific T cells made resistant to a common immunosuppressant, tacrolimus, for optimized performance in the immunosuppressed patient. Using a ribonucleoprotein approach of CRISPR-Cas9 technology, we have generated tacrolimus-resistant SARS-CoV-2-specific T cell products from convalescent donors and demonstrate their specificity and function through characterizations at the single-cell level, including flow cytometry, single-cell RNA (scRNA) Cellular Indexing of Transcriptomes and Epitopes (CITE), and T cell receptor (TCR) sequencing analyses. Based on the promising results, we aim for clinical validation of this approach in transplant recipients. Additionally, we propose a combinatory approach with tacrolimus, to prevent an overshooting immune response manifested as bystander T cell activation in the setting of severe COVID-19 immunopathology, and tacrolimus-resistant SARS-CoV-2-specific T cell products, allowing for efficient clearance of viral infection. Our strategy has the potential to prevent severe COVID-19 courses in SOT or autoimmunity settings and to prevent immunopathology while providing viral clearance in severe non-transplant COVID-19 cases.}, language = {en} }