@phdthesis{Lu2012,
  author    = {Lu, Dandan},
  title     = {ROS transcriptional networks controlling cell expansion during leaf growth in Arabidopsis thaliana},
  address   = {Potsdam},
  pages     = {121 S.},
  year      = {2012},
  language  = {en}
}
@misc{SchippersNguyenLuetal.2012,
  author    = {Schippers, Jos H. M. and Nguyen, Hung M. and Lu, Dandan and Schmidt, Romy and M{\"u}ller-R{\"o}ber, Bernd},
  title     = {ROS homeostasis during development: an evolutionary conserved strategy},
  series = {Cellular and molecular life sciences},
  volume    = {69},
  journal   = {Cellular and molecular life sciences},
  number    = {19},
  publisher = {Springer},
  address   = {Basel},
  issn      = {1420-682X},
  doi       = {10.1007/s00018-012-1092-4},
  pages     = {3245 -- 3257},
  year      = {2012},
  abstract  = {The balance between cellular proliferation and differentiation is a key aspect of development in multicellular organisms. Recent studies on Arabidopsis roots revealed distinct roles for different reactive oxygen species (ROS) in these processes. Modulation of the balance between ROS in proliferating cells and elongating cells is controlled at least in part at the transcriptional level. The effect of ROS on proliferation and differentiation is not specific for plants but appears to be conserved between prokaryotic and eukaryotic life forms. The ways in which ROS is received and how it affects cellular functioning is discussed from an evolutionary point of view. The different redox-sensing mechanisms that evolved ultimately result in the activation of gene regulatory networks that control cellular fate and decision-making. This review highlights the potential common origin of ROS sensing, indicating that organisms evolved similar strategies for utilizing ROS during development, and discusses ROS as an ancient universal developmental regulator.},
  language  = {en}
}
@article{LuWangPerssonetal.2014,
  author    = {Lu, Dandan and Wang, Ting and Persson, Staffan and M{\"u}ller-R{\"o}ber, Bernd and Schippers, Jos H. M.},
  title     = {Transcriptional control of ROS homeostasis by KUODA1 regulates cell expansion during leaf development},
  series = {Nature Communications},
  volume    = {5},
  journal   = {Nature Communications},
  publisher = {Nature Publ. Group},
  address   = {London},
  issn      = {2041-1723},
  doi       = {10.1038/ncomms4767},
  pages     = {9},
  year      = {2014},
  abstract  = {The final size of an organism, or of single organs within an organism, depends on an intricate coordination of cell proliferation and cell expansion. Although organism size is of fundamental importance, the molecular and genetic mechanisms that control it remain far from understood. Here we identify a transcription factor, KUODA1 (KUA1), which specifically controls cell expansion during leaf development in Arabidopsis thaliana. We show that KUA1 expression is circadian regulated and depends on an intact clock. Furthermore, KUA1 directly represses the expression of a set of genes encoding for peroxidases that control reactive oxygen species (ROS) homeostasis in the apoplast. Disruption of KUA1 results in increased peroxidase activity and smaller leaf cells. Chemical or genetic interference with the ROS balance or peroxidase activity affects cell size in a manner consistent with the identified KUA1 function. Thus, KUA1 modulates leaf cell expansion and final organ size by controlling ROS homeostasis.},
  language  = {en}
}