@article{AbeysekaraBenbowBirdetal.2018, author = {Abeysekara, A. U. and Benbow, Wystan and Bird, Ralph and Brill, A. and Brose, Robert and Buckley, J. H. and Chromey, A. J. and Daniel, M. K. and Falcone, A. and Finley, J. P. and Fortson, L. and Furniss, Amy and Gent, A. and Gillanders, Gerald H. and Hanna, David and Hassan, T. and Hervet, O. and Holder, J. and Hughes, G. and Humensky, T. B. and Kaaret, Philip and Kar, P. and Kertzman, M. and Kieda, David and Krause, Maria and Krennrich, F. and Kumar, S. and Lang, M. J. and Lin, T. T. Y. and Maier, Gernot and Moriarty, P. and Mukherjee, Reshmi and Ong, R. A. and Otte, Adam Nepomuk and Park, Nahee and Petrashyk, A. and Pohl, Martin and Pueschel, Elisa and Quinn, J. and Ragan, K. and Richards, Gregory T. and Roache, E. and Sadeh, I. and Santander, Marcos and Schlenstedt, S. and Sembroski, G. H. and Sushch, Iurii and Tyler, J. and Vassiliev, V. V. and Wakely, S. P. and Weinstein, A. and Wells, R. M. and Wilcox, P. and Wilhelm, Alina and Williams, David A. and Williamson, T. J. and Zitzer, B. and Acciari, V. A. and Ansoldi, S. and Antonelli, L. A. and Engels, A. Arbet and Baack, D. and Babic, A. and Banerjee, B. and de Almeida, U. Barres and Barrio, J. A. and Becerra Gonzalez, Josefa and Bednarek, Wlodek and Bernardini, Elisa and Berti, A. and Besenrieder, J. and Bhattacharyya, W. and Bigongiari, C. and Biland, A. and Blanch, O. and Bonnoli, G. and Busetto, G. and Carosi, R. and Ceribella, G. and Cikota, S. and Colak, S. M. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Da Vela, P. and Dazzi, F. and De Angelis, A. and De Lotto, B. and Delfino, M. and Delgado, J. and Di Pierro, F. and Do Souto Espinera, E. and Dominguez, A. and Prester, D. Dominis and Dorner, D. and Doro, M. and Einecke, S. and Elsaesser, D. and Ramazani, V. Fallah and Fattorini, A. and Fernandez-Barral, A. and Ferrara, G. and Fidalgo, D. and Foffano, L. and Fonseca, M. V. and Font, L. and Fruck, C. and Galindo, D. and Gallozzi, S. and Lopez, R. J. Garcia and Garczarczyk, M. and Gasparyan, S. and Gaug, Markus and Giammaria, P. and Godinovic, N. and Guberman, D. and Hadasch, D. and Hahn, A. and Herrera, J. and Hoang, J. and Hrupec, D. and Inoue, S. and Ishio, K. and Iwamura, Y. and Kubo, H. and Kushida, J. and Kuvezdic, D. and Lamastra, A. and Lelas, D. and Leone, Francesco and Lindfors, E. and Lombardi, S. and Longo, Francesco and Lopez, M. and Lopez-Oramas, A. and Machado de Oliveira Fraga, B. and Maggio, C. and Majumdar, P. and Makariev, M. and Mallamaci, M. and Maneva, G. and Manganaro, M. and Mannheim, K. and Maraschi, L. and Mariotti, M. and Martinez, M. and Masuda, S. and Mazin, D. and Minev, M. and Miranda, J. M. and Mirzoyan, R. and Molina, E. and Moralejo, A. and Moreno, V. and Moretti, E. and Munar-Adrover, Pere and Neustroev, V. and Niedzwiecki, Andrzej and Rosillo, Mireia Nievas and Nigro, C. and Nilsson, Kari and Ninci, D. and Nishijima, K. and Noda, K. and Nogues, L. and Noethe, M. and Paiano, Simona and Palacio, J. and Paneque, D. and Paoletti, R. and Paredes, J. M. and Pedaletti, G. and Penil, P. and Peresano, M. and Persic, M. and Moroni, P. G. Prada and Prandini, E. and Puljak, I. and Garcia, J. R. and Rhode, W. and Ribo, Marc and Rico, J. and Righi, C. and Rugliancich, A. and Saha, Lab and Sahakyan, Narek and Saito, T. and Satalecka, K. and Schweizer, T. and Sitarek, J. and Snidaric, I. and Sobczynska, D. and Somero, A. and Stamerra, A. and Strzys, M. and Suric, T. and Tavecchio, Fabrizio and Temnikov, P. and Terzic, T. and Teshima, M. and Torres-Alba, N. and Tsujimoto, S. and van Scherpenberg, J. and Vanzo, G. and Vazquez Acosta, M. and Vovk, I. and Will, M. and Zaric, D.}, title = {Periastron Observations of TeV Gamma-Ray Emission from a Binary System with a 50-year Period}, series = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, volume = {867}, journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics ; Part 2, Letters}, number = {1}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, organization = {VERITAS Collaboration MAGIC Collaboration}, issn = {2041-8205}, doi = {10.3847/2041-8213/aae70e}, pages = {8}, year = {2018}, abstract = {We report on observations of the pulsar/Be star binary system PSR J2032+4127/MT91 213 in the energy range between 100 GeV and 20 TeV with the Very Energetic Radiation Imaging Telescope Array and Major Atmospheric Gamma Imaging Cherenkov telescope arrays. The binary orbit has a period of approximately 50 years, with the most recent periastron occurring on 2017 November 13. Our observations span from 18 months prior to periastron to one month after. A new point-like gamma-ray source is detected, coincident with the location of PSR J2032+4127/MT91 213. The gamma-ray light curve and spectrum are well characterized over the periastron passage. The flux is variable over at least an order of magnitude, peaking at periastron, thus providing a firm association of the TeV source with the pulsar/Be star system. Observations prior to periastron show a cutoff in the spectrum at an energy around 0.5 TeV. This result adds a new member to the small population of known TeV binaries, and it identifies only the second source of this class in which the nature and properties of the compact object are firmly established. We compare the gamma-ray results with the light curve measured with the X-ray Telescope on board the Neil Gehrels Swift Observatory and with the predictions of recent theoretical models of the system. We conclude that significant revision of the models is required to explain the details of the emission that we have observed, and we discuss the relationship between the binary system and the overlapping steady extended source, TeV J2032+4130.}, language = {en} } @article{HorikoshiYaghootkarMookKanamorietal.2013, author = {Horikoshi, Momoko and Yaghootkar, Hanieh and Mook-Kanamori, Dennis O. and Sovio, Ulla and Taal, H. Rob and Hennig, Branwen J. and Bradfield, Jonathan P. and St Pourcain, Beate and Evans, David M. and Charoen, Pimphen and Kaakinen, Marika and Cousminer, Diana L. and Lehtimaki, Terho and Kreiner-Moller, Eskil and Warrington, Nicole M. and Bustamante, Mariona and Feenstra, Bjarke and Berry, Diane J. and Thiering, Elisabeth and Pfab, Thiemo and Barton, Sheila J. and Shields, Beverley M. and Kerkhof, Marjan and van Leeuwen, Elisabeth M. and Fulford, Anthony J. and Kutalik, Zoltan and Zhao, Jing Hua and den Hoed, Marcel and Mahajan, Anubha and Lindi, Virpi and Goh, Liang-Kee and Hottenga, Jouke-Jan and Wu, Ying and Raitakari, Olli T. and Harder, Marie N. and Meirhaeghe, Aline and Ntalla, Ioanna and Salem, Rany M. and Jameson, Karen A. and Zhou, Kaixin and Monies, Dorota M. and Lagou, Vasiliki and Kirin, Mirna and Heikkinen, Jani and Adair, Linda S. and Alkuraya, Fowzan S. and Al-Odaib, Ali and Amouyel, Philippe and Andersson, Ehm Astrid and Bennett, Amanda J. and Blakemore, Alexandra I. F. and Buxton, Jessica L. and Dallongeville, Jean and Das, Shikta and de Geus, Eco J. C. and Estivill, Xavier and Flexeder, Claudia and Froguel, Philippe and Geller, Frank and Godfrey, Keith M. and Gottrand, Frederic and Groves, Christopher J. and Hansen, Torben and Hirschhorn, Joel N. and Hofman, Albert and Hollegaard, Mads V. and Hougaard, David M. and Hyppoenen, Elina and Inskip, Hazel M. and Isaacs, Aaron and Jorgensen, Torben and Kanaka-Gantenbein, Christina and Kemp, John P. and Kiess, Wieland and Kilpelainen, Tuomas O. and Klopp, Norman and Knight, Bridget A. and Kuzawa, Christopher W. and McMahon, George and Newnham, John P. and Niinikoski, Harri and Oostra, Ben A. and Pedersen, Louise and Postma, Dirkje S. and Ring, Susan M. and Rivadeneira, Fernando and Robertson, Neil R. and Sebert, Sylvain and Simell, Olli and Slowinski, Torsten and Tiesler, Carla M. T. and Toenjes, Anke and Vaag, Allan and Viikari, Jorma S. and Vink, Jacqueline M. and Vissing, Nadja Hawwa and Wareham, Nicholas J. and Willemsen, Gonneke and Witte, Daniel R. and Zhang, Haitao and Zhao, Jianhua and Wilson, James F. and Stumvoll, Michael and Prentice, Andrew M. and Meyer, Brian F. and Pearson, Ewan R. and Boreham, Colin A. G. and Cooper, Cyrus and Gillman, Matthew W. and Dedoussis, George V. and Moreno, Luis A. and Pedersen, Oluf and Saarinen, Maiju and Mohlke, Karen L. and Boomsma, Dorret I. and Saw, Seang-Mei and Lakka, Timo A. and Koerner, Antje and Loos, Ruth J. F. and Ong, Ken K. and Vollenweider, Peter and van Duijn, Cornelia M. and Koppelman, Gerard H. and Hattersley, Andrew T. and Holloway, John W. and Hocher, Berthold and Heinrich, Joachim and Power, Chris and Melbye, Mads and Guxens, Monica and Pennell, Craig E. and Bonnelykke, Klaus and Bisgaard, Hans and Eriksson, Johan G. and Widen, Elisabeth and Hakonarson, Hakon and Uitterlinden, Andre G. and Pouta, Anneli and Lawlor, Debbie A. and Smith, George Davey and Frayling, Timothy M. and McCarthy, Mark I. and Grant, Struan F. A. and Jaddoe, Vincent W. V. and Jarvelin, Marjo-Riitta and Timpson, Nicholas J. and Prokopenko, Inga and Freathy, Rachel M.}, title = {New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism}, series = {Nature genetics}, volume = {45}, journal = {Nature genetics}, number = {1}, publisher = {Nature Publ. Group}, address = {New York}, organization = {MAGIC, Early Growth Genetics EGG}, issn = {1061-4036}, doi = {10.1038/ng.2477}, pages = {76 -- U115}, year = {2013}, abstract = {Birth weight within the normal range is associated with a variety of adult-onset diseases, but the mechanisms behind these associations are poorly understood(1). Previous genome-wide association studies of birth weight identified a variant in the ADCY5 gene associated both with birth weight and type 2 diabetes and a second variant, near CCNL1, with no obvious link to adult traits(2). In an expanded genome-wide association metaanalysis and follow-up study of birth weight (of up to 69,308 individuals of European descent from 43 studies), we have now extended the number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking. Five of the loci are known to be associated with other phenotypes: ADCY5 and CDKAL1 with type 2 diabetes, ADRB1 with adult blood pressure and HMGA2 and LCORL with adult height. Our findings highlight genetic links between fetal growth and postnatal growth and metabolism.}, language = {en} } @article{BeaulieuBennettFouqueetal.2006, author = {Beaulieu, Jean-Philippe and Bennett, David P. and Fouqu{\´e}, Pascal and Williams, Andrew and Dominik, Martin and Jorgensen, Uffe Grae and Kubas, Daniel and Cassan, Arnaud and Coutures, Christian and Greenhill, John and Hill, Kym and Menzies, John and Sackett, Penny D. and Albrow, Michael D. and Brillant, Stephane and Caldwell, John A. R. and Calitz, Johannes Jacobus and Cook, Kem H. and Corrales Cosmeli, Esperanza de Santa Cecilia and Desort, Morgan and Dieters, Stefan and Dominis, Dijana and Donatowicz, Jadzia and Hoffman, Martie and Kane, Stephen R. and Marquette, Jean-Baptiste and Martin, Ralph and Meintjes, Pieter and Pollard, Karen R. and Sahu, Kailash C. and Vinter, Christian and Wambsganss, Joachim and Woller, Kristian and Horne, Keith and Steele, Iain and Bramich, Daniel M. and Burgdorf, Martin and Snodgrass, Colin and Bode, Mike and Udalski, Andr}, title = {Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing}, issn = {0028-0836}, doi = {10.1038/Nature04441}, year = {2006}, abstract = {In the favoured core-accretion model of formation of planetary systems, solid planetesimals accumulate to build up planetary cores, which then accrete nebular gas if they are sufficiently massive. Around M-dwarf stars ( the most common stars in our Galaxy), this model favours the formation of Earth-mass (M+) to Neptune-mass planets with orbital radii of 1 to 10 astronomical units (AU), which is consistent with the small number of gas giant planets known to orbit M-dwarf host stars(1-4). More than 170 extrasolar planets have been discovered with a wide range of masses and orbital periods, but planets of Neptune's mass or less have not hitherto been detected at separations of more than 0.15 AU from normal stars. Here we report the discovery of a 5.5(-2.7)(+5.5)M(+) planetary companion at a separation of 2.6(- 0.6)(+1.5) AU from a 0.22(-0.11)(+0.21)M(.) M-dwarf star, where M-. refers to a solar mass. (We propose to name it OGLE- 2005-BLG-390Lb, indicating a planetary mass companion to the lens star of the microlensing event.) The mass is lower than that of GJ876d (ref. 5), although the error bars overlap. Our detection suggests that such cool, sub-Neptune-mass planets may be more common than gas giant planets, as predicted by the core accretion theory.}, language = {en} } @article{SteffenRoeckstromRichardsonetal.2018, author = {Steffen, Will and R{\"o}ckstrom, Johan and Richardson, Katherine and Lenton, Timothy M. and Folke, Carl and Liverman, Diana and Summerhayes, Colin P. and Barnosky, Anthony D. and Cornell, Sarah E. and Crucifix, Michel and Donges, Jonathan and Fetzer, Ingo and Lade, Steven J. and Scheffer, Marten and Winkelmann, Ricarda and Schellnhuber, Hans Joachim}, title = {Trajectories of the Earth System in the Anthropocene}, series = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {115}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, number = {33}, publisher = {National Acad. of Sciences}, address = {Washington}, issn = {0027-8424}, doi = {10.1073/pnas.1810141115}, pages = {8252 -- 8259}, year = {2018}, abstract = {We explore the risk that self-reinforcing feedbacks could push the Earth System toward a planetary threshold that, if crossed, could prevent stabilization of the climate at intermediate temperature rises and cause continued warming on a "Hothouse Earth" pathway even as human emissions are reduced. Crossing the threshold would lead to a much higher global average temperature than any interglacial in the past 1.2 million years and to sea levels significantly higher than at any time in the Holocene. We examine the evidence that such a threshold might exist and where it might be. If the threshold is crossed, the resulting trajectory would likely cause serious disruptions to ecosystems, society, and economies. Collective human action is required to steer the Earth System away from a potential threshold and stabilize it in a habitable interglacial-like state. Such action entails stewardship of the entire Earth System-biosphere, climate, and societies-and could include decarbonization of the global economy, enhancement of biosphere carbon sinks, behavioral changes, technological innovations, new governance arrangements, and transformed social values.}, language = {en} }