@misc{JobstKnoblochLeitneretal.2006, author = {Jobst, Anne and Knobloch, Eberhard and Leitner, Ulrike and Mikosch, Regina and Pieper, Herbert and Schwarz, Ingo and Bourguet, Marie-No{\"e}lle and Ette, Ottmar and Suckow, Christian and Thiemer-Sachse, Ursula and Faak, Margot}, title = {HiN : Alexander von Humboldt im Netz = Festschrift f{\"u}r Margot Faak zu Ehren ihres 80. Geburtstages}, volume = {VII}, number = {13}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, doi = {10.18443/hinvol7iss132006}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-35709}, pages = {115}, year = {2006}, abstract = {Inhalt: - Die Mitarbeiter der Avh-Forschungsstelle: Margot Faak zum 80. Geburtstag - Marie-No{\"e}lle Bourguet: La fabrique du savoir. Essai sur les carnets de voyage d'Alexander von Humboldt - Ottmar Ette: Unterwegs zu einer Weltwissenschaft? Alexander von Humboldts Weltbegriffe und die transarealen Studien - Eberhard Knobloch: Erkundung und Erforschung - Alexander von Humboldts Amerikareise - Herbert Pieper: Die Geognosie der Vulkane - Christian Suckow: Prinz Humboldt - Ursula Thiemer-Sachse: !'Qu{\´e} arte es comprender el arte ...! La visi{\´o}n del arte ind{\´i}gena de Am{\´e}rica por Alejandro de Humboldt - Margot Faak: G. W. Leibniz im Urteil Alexander von Humboldts - Regina Mikosch, Ingo Schwarz: Bibliographie zu Margot Faak}, language = {mul} } @misc{KnoblochKoelbelSauerweinetal.2008, author = {Knobloch, Eberhard and K{\"o}lbel, Bernd and Sauerwein, Martin and Sauerwein, Katrin and K{\"o}lbel, Steffen and Buckow, Cathleen and Leitner, Ulrike and Schwarz, Ingo and Suckow, Christian and Werner, Petra and Pieper, Herbert}, title = {HiN : Alexander von Humboldt im Netz = Herbert Pieper zum 65. Geburtstag}, volume = {IX}, number = {16}, editor = {Ette, Ottmar and Knobloch, Eberhard}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, issn = {1617-5239}, doi = {10.18443/hinvol9iss162008}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-42246}, pages = {65}, year = {2008}, abstract = {Herbert Pieper zum 65. Geburtstag Inhalt: - Eberhard Knobloch: Herbert Pieper zum 65. Geburtstag. Ein R{\"u}ckblick - Bernd K{\"o}lbel, Martin Sauerwein, Katrin Sauerwein, Steffen K{\"o}lbel, Cathleen Buckow: Das Fragment des englischen Tagebuches von Alexander von Humboldt - Ulrike Leitner: Humboldt, Cotta, Ritter. Eine Miszelle {\"u}ber die Arbeit an einer Edition - Ingo Schwarz: "da ich mich lebhaft f{\"u}r sein Schiksal im Neuen Continent interessire". A. v. Humboldt als F{\"o}rderer Oscar M. Liebers - Christian Suckow: Humboldts spanische Option 1830. Eine Nachlese - Petra Werner: Bemerkungen zu Alexander von Humboldts Russland-Tagebuch - Herbert Pieper Alexander von Humboldts Wahl in die Akademie der Wissenschaften zu Berlin - Publikationen von Herbert Pieper [Bibliographie]}, language = {de} } @article{PieperMarekUnterbergetal.2014, author = {Pieper, Christian and Marek, Jasmin Jacqueline and Unterberg, Marlies and Schwerdtle, Tanja and Galla, Hans-Joachim}, title = {Brain capillary pericytes contribute to the immune defense in response to cytokines or LPS in vitro}, series = {Brain research : an international multidisciplinary journal devoted to fundamental research in the brain sciences}, volume = {1550}, journal = {Brain research : an international multidisciplinary journal devoted to fundamental research in the brain sciences}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0006-8993}, doi = {10.1016/j.brainres.2014.01.004}, pages = {1 -- 8}, year = {2014}, abstract = {The prevention of an inflammation in the brain is one of the most important goals the body has to achieve. As pericytes are located on the abluminal side of the capillaries in the brain, their role in fighting against invading pathogens has been investigated in some points, mostly in their ability to behave like macrophages. Here we studied the potential of pericytes to react as immune cells under inflammatory conditions, especially regarding the expression of the inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), major histocompatibility complex II (MHC II) molecules, CD68, as well as the generation of reactive oxygen and nitrogen species (RONS), and their ability in phagocytosis. Quantitative real time PCR and western blot analysis showed that pericytes are able to increase the expression of typical inflammatory marker proteins after the stimulation with tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1 beta), interferon-gamma (IFN-gamma), or lipopolysaccharides (LPS). Depending on the different specific pro-inflammatory factors pericytes changed the expression of alpha smooth muscle actin (alpha SMA), the most predominant pericyte marker. We conclude that the role of the pericytes within the immune system is regulated and fine-tuned by different cytokines strongly depending on the time when the cytokines are released and their concentration. The present results will help to understand the pericyte mediated defense mechanisms in the brain.}, language = {en} }