@article{PenoneAllanSoliveresetal.2019,
  author    = {Penone, Caterina and Allan, Eric and Soliveres, Santiago and Felipe-Lucia, Maria R. and Gossner, Martin M. and Seibold, Sebastian and Simons, Nadja K. and Schall, Peter and van der Plas, Fons and Manning, Peter and Manzanedo, Ruben D. and Boch, Steffen and Prati, Daniel and Ammer, Christian and Bauhus, Juergen and Buscot, Francois and Ehbrecht, Martin and Goldmann, Kezia and Jung, Kirsten and Mueller, Joerg and Mueller, Joerg C. and Pena, Rodica and Polle, Andrea and Renner, Swen C. and Ruess, Liliane and Schoenig, Ingo and Schrumpf, Marion and Solly, Emily F. and Tschapka, Marco and Weisser, Wolfgang W. and Wubet, Tesfaye and Fischer, Markus},
  title     = {Specialisation and diversity of multiple trophic groups are promoted by different forest features},
  series = {Ecology letters},
  volume    = {22},
  journal   = {Ecology letters},
  number    = {1},
  publisher = {Wiley},
  address   = {Hoboken},
  issn      = {1461-023X},
  doi       = {10.1111/ele.13182},
  pages     = {170 -- 180},
  year      = {2019},
  abstract  = {While forest management strongly influences biodiversity, it remains unclear how the structural and compositional changes caused by management affect different community dimensions (e.g. richness, specialisation, abundance or completeness) and how this differs between taxa. We assessed the effects of nine forest features (representing stand structure, heterogeneity and tree composition) on thirteen above- and belowground trophic groups of plants, animals, fungi and bacteria in 150 temperate forest plots differing in their management type. Canopy cover decreased light resources, which increased community specialisation but reduced overall diversity and abundance. Features increasing resource types and diversifying microhabitats (admixing of oaks and conifers) were important and mostly affected richness. Belowground groups responded differently to those aboveground and had weaker responses to most forest features. Our results show that we need to consider forest features rather than broad management types and highlight the importance of considering several groups and community dimensions to better inform conservation.},
  language  = {en}
}
@article{HeinrichsAmmerMundetal.2019,
  author    = {Heinrichs, Steffi and Ammer, Christian and Mund, Martina and Boch, Steffen and Budde, Sabine and Fischer, Markus and Mueller, Joerg and Schoening, Ingo and Schulze, Ernst-Detlef and Schmidt, Wolfgang and Weckesser, Martin and Schall, Peter},
  title     = {Landscape-Scale Mixtures of Tree Species are More Effective than Stand-Scale Mixtures for Biodiversity of Vascular Plants, Bryophytes and Lichens},
  series = {Forests},
  volume    = {10},
  journal   = {Forests},
  number    = {1},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1999-4907},
  doi       = {10.3390/f10010073},
  pages     = {34},
  year      = {2019},
  abstract  = {Tree species diversity can positively affect the multifunctionality of forests. This is why conifer monocultures of Scots pine and Norway spruce, widely promoted in Central Europe since the 18th and 19th century, are currently converted into mixed stands with naturally dominant European beech. Biodiversity is expected to benefit from these mixtures compared to pure conifer stands due to increased abiotic and biotic resource heterogeneity. Evidence for this assumption is, however, largely lacking. Here, we investigated the diversity of vascular plants, bryophytes and lichens at the plot (alpha diversity) and at the landscape (gamma diversity) level in pure and mixed stands of European beech and conifer species (Scots pine, Norway spruce, Douglas fir) in four regions in Germany. We aimed to identify compositions of pure and mixed stands in a hypothetical forest landscape that can optimize gamma diversity of vascular plants, bryophytes and lichens within regions. Results show that gamma diversity of the investigated groups is highest when a landscape comprises different pure stands rather than tree species mixtures at the stand scale. Species mainly associated with conifers rely on light regimes that are only provided in pure conifer forests, whereas mixtures of beech and conifers are more similar to beech stands. Combining pure beech and pure conifer stands at the landscape scale can increase landscape level biodiversity and conserve species assemblages of both stand types, while landscapes solely composed of stand scale tree species mixtures could lead to a biodiversity reduction of a combination of investigated groups of 7 up to 20\%.},
  language  = {en}
}
@article{RoedelOttenDonatetal.2019,
  author    = {R{\"o}del, Claudia Jasmin and Otten, Cecile and Donat, Stefan and Louren{\c{c}}o, Marta Sofia Rocha and Fischer, Dorothea and Kuropka, Benno and Paolini, Alessio and Freund, Christian and Abdelilah-Seyfried, Salim},
  title     = {Blood Flow Suppresses Vascular Anomalies in a Zebrafish Model of Cerebral Cavernous Malformations},
  series = {Circulation Research},
  volume    = {125},
  journal   = {Circulation Research},
  number    = {10},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  issn      = {0009-7330},
  doi       = {10.1161/CIRCRESAHA.119.315076},
  pages     = {E43 -- E54},
  year      = {2019},
  abstract  = {RATIONALE: Pathological biomechanical signaling induces vascular anomalies including cerebral cavernous malformations (CCM), which are caused by a clonal loss of CCM1/KRIT1 (Krev interaction trapped protein 1), CCM2/MGC4607, or CCM3/PDCD10. Why patients typically experience lesions only in lowly perfused venous capillaries of the cerebrovasculature is completely unknown. OBJECTIVE: In contrast, animal models with a complete loss of CCM proteins lack a functional heart and blood flow and exhibit vascular anomalies within major blood vessels as well. This finding raises the possibility that hemodynamics may play a role in the context of this vascular pathology. METHODS AND RESULTS: Here, we used a genetic approach to restore cardiac function and blood flow in a zebrafish model of CCM1. We find that blood flow prevents cardiovascular anomalies including a hyperplastic expansion within a large Ccm1-deficient vascular bed, the lateral dorsal aorta. CONCLUSIONS: This study identifies blood flow as an important physiological factor that is protective in the cause of this devastating vascular pathology.},
  language  = {en}
}
@article{VockWeigandPreckeletal.2021,
  author    = {Vock, Miriam and Weigand, Gabriele and Preckel, Franzis and Fischer, Christian and K{\"a}pnick, Friedhelm and Perleth, Christoph and Wollerstein, Werner},
  title     = {Wissenschaftlicher Hintergrund des LemaS-Projekts},
  series = {Leistung macht Schule : F{\"o}rderung leistungsstarker und potenziell besonders leistungsf{\"a}higer Sch{\"u}lerinnen und Sch{\"u}ler},
  journal   = {Leistung macht Schule : F{\"o}rderung leistungsstarker und potenziell besonders leistungsf{\"a}higer Sch{\"u}lerinnen und Sch{\"u}ler},
  edition   = {2},
  publisher = {Beltz},
  address   = {Weinheim},
  isbn      = {978-3-40725-883-0},
  pages     = {23 -- 30},
  year      = {2021},
  language  = {de}
}
@article{SchmidtReilJeskeetal.2021,
  author    = {Schmidt, Sabrina and Reil, Daniela and Jeske, Kathrin and Drewes, Stephan and Rosenfeld, Ulrike and Fischer, Stefan and Spierling, Nastasja G. and Labutin, Anton and Heckel, Gerald and Jacob, Jens and Ulrich, Rainer G. and Imholt, Christian},
  title     = {Spatial and temporal dynamics and molecular evolution of Tula orthohantavirus in German vole populations},
  series = {Viruses / Molecular Diversity Preservation International (MDPI)},
  volume    = {13},
  journal   = {Viruses / Molecular Diversity Preservation International (MDPI)},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1999-4915},
  doi       = {10.3390/v13061132},
  pages     = {17},
  year      = {2021},
  abstract  = {Tula orthohantavirus (TULV) is a rodent-borne hantavirus with broad geographical distribution in Europe. Its major reservoir is the common vole (Microtus arvalis), but TULV has also been detected in closely related vole species. Given the large distributional range and high amplitude population dynamics of common voles, this host-pathogen complex presents an ideal system to study the complex mechanisms of pathogen transmission in a wild rodent reservoir. We investigated the dynamics of TULV prevalence and the subsequent potential effects on the molecular evolution of TULV in common voles of the Central evolutionary lineage. Rodents were trapped for three years in four regions of Germany and samples were analyzed for the presence of TULV-reactive antibodies and TULV RNA with subsequent sequence determination. The results show that individual (sex) and population-level factors (abundance) of hosts were significant predictors of local TULV dynamics. At the large geographic scale, different phylogenetic TULV clades and an overall isolation-by-distance pattern in virus sequences were detected, while at the small scale (<4 km) this depended on the study area. In combination with an overall delayed density dependence, our results highlight that frequent, localized bottleneck events for the common vole and TULV do occur and can be offset by local recolonization dynamics.},
  language  = {en}
}