@article{WeissWaltersMorishitaetal.2020,
author = {Weiss, Jonathan R. and Walters, Richard J. and Morishita, Yu and Wright, Tim J. and Lazecky, Milan and Wang, Hua and Hussain, Ekbal and Hooper, Andrew J. and Elliott, John R. and Rollins, Chris and Yu, Chen and Gonzalez, Pablo J. and Spaans, Karsten and Li, Zhenhong and Parsons, Barry},
title = {High-resolution surface velocities and strain for Anatolia from Sentinel-1 InSAR and GNSS data},
series = {Geophysical research letters},
volume = {47},
journal = {Geophysical research letters},
number = {17},
publisher = {American Geophysical Union},
address = {Washington},
issn = {0094-8276},
doi = {10.1029/2020GL087376},
pages = {12},
year = {2020},
abstract = {Measurements of present-day surface deformation are essential for the assessment of long-term seismic hazard. The European Space Agency's Sentinel-1 satellites enable global, high-resolution observation of crustal motion from Interferometric Synthetic Aperture Radar (InSAR). We have developed automated InSAR processing systems that exploit the first similar to 5 years of Sentinel-1 data to measure surface motions for the similar to 800,000-km(2) Anatolian region. Our new 3-D velocity and strain rate fields illuminate deformation patterns dominated by westward motion of Anatolia relative to Eurasia, localized strain accumulation along the North and East Anatolian Faults, and rapid vertical signals associated with anthropogenic activities and to a lesser extent extension across the grabens of western Anatolia. We show that automatically processed Sentinel-1 InSAR data can characterize details of the velocity and strain rate fields with high resolution and accuracy over large regions. These results are important for assessing the relationship between strain accumulation and release in earthquakes.
Plain Language Summary Satellite-based measurements of small rates of motion of the Earth's surface made at high spatial resolutions and over large areas are important for many geophysical applications including improving earthquake hazard models. We take advantage of recent advances in geodetic techniques in order to measure surface velocities and tectonic strain accumulation across the Anatolia region, including the highly seismogenic and often deadly North Anatolian Fault. We show that by combining Sentinel-1 Interferometric Synthetic Aperture Radar (InSAR) data with Global Navigation Satellite System (GNSS) measurements we can enhance our view of surface deformation associated with active tectonics, the earthquake cycle, and anthropogenic processes.},
language = {en}
}
@article{XuDongJieetal.2022,
author = {Xu, Yaolin and Dong, Kang and Jie, Yulin and Adelhelm, Philipp and Chen, Yawei and Xu, Liang and Yu, Peiping and Kim, Junghwa and Kochovski, Zdravko and Yu, Zhilong and Li, Wanxia and LeBeau, James and Shao-Horn, Yang and Cao, Ruiguo and Jiao, Shuhong and Cheng, Tao and Manke, Ingo and Lu, Yan},
title = {Promoting mechanistic understanding of lithium deposition and solid-electrolyte interphase (SEI) formation using advanced characterization and simulation methods: recent progress, limitations, and future perspectives},
series = {Avanced energy materials},
volume = {12},
journal = {Avanced energy materials},
number = {19},
publisher = {Wiley},
address = {Weinheim},
issn = {1614-6832},
doi = {10.1002/aenm.202200398},
pages = {22},
year = {2022},
abstract = {In recent years, due to its great promise in boosting the energy density of lithium batteries for future energy storage, research on the Li metal anode, as an alternative to the graphite anode in Li-ion batteries, has gained significant momentum. However, the practical use of Li metal anodes has been plagued by unstable Li (re)deposition and poor cyclability. Although tremendous efforts have been devoted to the stabilization of Li metal anodes, the mechanisms of electrochemical (re-)deposition/dissolution of Li and solid-electrolyte-interphase (SEI) formation remain elusive. This article highlights the recent mechanistic understandings and observations of Li deposition/dissolution and SEI formation achieved from advanced characterization techniques and simulation methods, and discusses major limitations and open questions in these processes. In particular, the authors provide their perspectives on advanced and emerging/potential methods for obtaining new insights into these questions. In addition, they give an outlook into cutting-edge interdisciplinary research topics for Li metal anodes. It pushes beyond the current knowledge and is expected to accelerate development toward a more in-depth and comprehensive understanding, in order to guide future research on Li metal anodes toward practical application.},
language = {en}
}
@article{WuttkeLiLietal.2019,
author = {Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B. and Feitosa, Mary F. and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y. and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O. and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and Van der Most, Peter J. and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer Singh and Almgren, Peter and Amin, Najaf and Arnlov, Johan and Bakker, Stephan J. L. and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L. and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and B{\"o}ttinger, Erwin and Boutin, Thibaud S. and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S. and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickael and Carroll, Robert J. and Catamo, Eulalia and Chambers, John C. and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P. and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and De Borst, Martin H. and De Grandi, Alessandro and De Mutsert, Renee and De Vries, Aiko P. J. and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K. and Felix, Janine F. and Foo, Valencia Hui Xian and Franco, Oscar H. and Franke, Andre and Freedman, Barry I. and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T. and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and Girotto, Giorgia and Giulianini, Franco and Gogele, Martin and Gordon, Scott D. and Gudbjartsson, Daniel F. and Gudnason, Vilmundur and Haller, Toomas and Hamet, Pavel and Harris, Tamara B. and Hartman, Catharina A. and Hayward, Caroline and Hellwege, Jacklyn N. and Heng, Chew-Kiat and Hicks, Andrew A. and Hofer, Edith and Huang, Wei and Hutri-Kahonen, Nina and Hwang, Shih-Jen and Ikram, M. Arfan and Indridason, Olafur S. and Ingelsson, Erik and Ising, Marcus and Jaddoe, Vincent W. V. and Jakobsdottir, Johanna and Jonas, Jost B. and Joshi, Peter K. and Josyula, Navya Shilpa and Jung, Bettina and Kahonen, Mika and Kamatani, Yoichiro and Kammerer, Candace M. and Kanai, Masahiro and Kastarinen, Mika and Kerr, Shona M. and Khor, Chiea-Chuen and Kiess, Wieland and Kleber, Marcus E. and Koenig, Wolfgang and Kooner, Jaspal S. and Korner, Antje and Kovacs, Peter and Kraja, Aldi T. and Krajcoviechova, Alena and Kramer, Holly and Kramer, Bernhard K. and Kronenberg, Florian and Kubo, Michiaki and Kuhnel, Brigitte and Kuokkanen, Mikko and Kuusisto, Johanna and La Bianca, Martina and Laakso, Markku and Lange, Leslie A. and Langefeld, Carl D. and Lee, Jeannette Jen-Mai and Lehne, Benjamin and Lehtimaki, Terho and Lieb, Wolfgang and Lim, Su-Chi and Lind, Lars and Lindgren, Cecilia M. and Liu, Jun and Liu, Jianjun and Loeffler, Markus and Loos, Ruth J. F. and Lucae, Susanne and Lukas, Mary Ann and Lyytikainen, Leo-Pekka and Magi, Reedik and Magnusson, Patrik K. E. and Mahajan, Anubha and Martin, Nicholas G. and Martins, Jade and Marz, Winfried and Mascalzoni, Deborah and Matsuda, Koichi and Meisinger, Christa and Meitinger, Thomas and Melander, Olle and Metspalu, Andres and Mikaelsdottir, Evgenia K. and Milaneschi, Yuri and Miliku, Kozeta and Mishra, Pashupati P. and Program, V. A. Million Veteran and Mohlke, Karen L. and Mononen, Nina and Montgomery, Grant W. and Mook-Kanamori, Dennis O. and Mychaleckyj, Josyf C. and Nadkarni, Girish N. and Nalls, Mike A. and Nauck, Matthias and Nikus, Kjell and Ning, Boting and Nolte, Ilja M. and Noordam, Raymond and Olafsson, Isleifur and Oldehinkel, Albertine J. and Orho-Melander, Marju and Ouwehand, Willem H. and Padmanabhan, Sandosh and Palmer, Nicholette D. and Palsson, Runolfur and Penninx, Brenda W. J. H. and Perls, Thomas and Perola, Markus and Pirastu, Mario and Pirastu, Nicola and Pistis, Giorgio and Podgornaia, Anna I. and Polasek, Ozren and Ponte, Belen and Porteous, David J. and Poulain, Tanja and Pramstaller, Peter P. and Preuss, Michael H. and Prins, Bram P. and Province, Michael A. and Rabelink, Ton J. and Raffield, Laura M. and Raitakari, Olli T. and Reilly, Dermot F. and Rettig, Rainer and Rheinberger, Myriam and Rice, Kenneth M. and Ridker, Paul M. and Rivadeneira, Fernando and Rizzi, Federica and Roberts, David J. and Robino, Antonietta and Rossing, Peter and Rudan, Igor and Rueedi, Rico and Ruggiero, Daniela and Ryan, Kathleen A. and Saba, Yasaman and Sabanayagam, Charumathi and Salomaa, Veikko and Salvi, Erika and Saum, Kai-Uwe and Schmidt, Helena and Schmidt, Reinhold and Ben Schottker, and Schulz, Christina-Alexandra and Schupf, Nicole and Shaffer, Christian M. and Shi, Yuan and Smith, Albert V. and Smith, Blair H. and Soranzo, Nicole and Spracklen, Cassandra N. and Strauch, Konstantin and Stringham, Heather M. and Stumvoll, Michael and Svensson, Per O. and Szymczak, Silke and Tai, E-Shyong and Tajuddin, Salman M. and Tan, Nicholas Y. Q. and Taylor, Kent D. and Teren, Andrej and Tham, Yih-Chung and Thiery, Joachim and Thio, Chris H. L. and Thomsen, Hauke and Thorleifsson, Gudmar and Toniolo, Daniela and Tonjes, Anke and Tremblay, Johanne and Tzoulaki, Ioanna and Uitterlinden, Andre G. and Vaccargiu, Simona and Van Dam, Rob M. and Van der Harst, Pim and Van Duijn, Cornelia M. and Edward, Digna R. Velez and Verweij, Niek and Vogelezang, Suzanne and Volker, Uwe and Vollenweider, Peter and Waeber, Gerard and Waldenberger, Melanie and Wallentin, Lars and Wang, Ya Xing and Wang, Chaolong and Waterworth, Dawn M. and Bin Wei, Wen and White, Harvey and Whitfield, John B. and Wild, Sarah H. and Wilson, James F. and Wojczynski, Mary K. and Wong, Charlene and Wong, Tien-Yin and Xu, Liang and Yang, Qiong and Yasuda, Masayuki and Yerges-Armstrong, Laura M. and Zhang, Weihua and Zonderman, Alan B. and Rotter, Jerome I. and Bochud, Murielle and Psaty, Bruce M. and Vitart, Veronique and Wilson, James G. and Dehghan, Abbas and Parsa, Afshin and Chasman, Daniel I. and Ho, Kevin and Morris, Andrew P. and Devuyst, Olivier and Akilesh, Shreeram and Pendergrass, Sarah A. and Sim, Xueling and Boger, Carsten A. and Okada, Yukinori and Edwards, Todd L. and Snieder, Harold and Stefansson, Kari and Hung, Adriana M. and Heid, Iris M. and Scholz, Markus and Teumer, Alexander and Kottgen, Anna and Pattaro, Cristian},
title = {A catalog of genetic loci associated with kidney function from analyses of a million individuals},
series = {Nature genetics},
volume = {51},
journal = {Nature genetics},
number = {6},
publisher = {Nature Publ. Group},
address = {New York},
organization = {Lifelines COHort Study},
issn = {1061-4036},
doi = {10.1038/s41588-019-0407-x},
pages = {957 -- +},
year = {2019},
abstract = {Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide association studies of estimated glomerular filtration rate (eGFR) and independent replication (n = 1,046,070), we identified 264 associated loci (166 new). Of these,147 were likely to be relevant for kidney function on the basis of associations with the alternative kidney function marker blood urea nitrogen (n = 416,178). Pathway and enrichment analyses, including mouse models with renal phenotypes, support the kidney as the main target organ. A genetic risk score for lower eGFR was associated with clinically diagnosed CKD in 452,264 independent individuals. Colocalization analyses of associations with eGFR among 783,978 European-ancestry individuals and gene expression across 46 human tissues, including tubulo-interstitial and glomerular kidney compartments, identified 17 genes differentially expressed in kidney. Fine-mapping highlighted missense driver variants in 11 genes and kidney-specific regulatory variants. These results provide a comprehensive priority list of molecular targets for translational research.},
language = {en}
}
@techreport{BrodeurMikolaCooketal.2024,
type = {Working Paper},
author = {Brodeur, Abel and Mikola, Derek and Cook, Nikolai and Brailey, Thomas and Briggs, Ryan and Gendre, Alexandra de and Dupraz, Yannick and Fiala, Lenka and Gabani, Jacopo and Gauriot, Romain and Haddad, Joanne and Lima, Goncalo and Ankel-Peters, J{\"o}rg and Dreber, Anna and Campbell, Douglas and Kattan, Lamis and Fages, Diego Marino and Mierisch, Fabian and Sun, Pu and Wright, Taylor and Connolly, Marie and Hoces de la Guardia, Fernando and Johannesson, Magnus and Miguel, Edward and Vilhuber, Lars and Abarca, Alejandro and Acharya, Mahesh and Adjisse, Sossou Simplice and Akhtar, Ahwaz and Lizardi, Eduardo Alberto Ramirez and Albrecht, Sabina and Andersen, Synve Nygaard and Andlib, Zubaria and Arrora, Falak and Ash, Thomas and Bacher, Etienne and Bachler, Sebastian and Bacon, F{\´e}lix and Bagues, Manuel and Balogh, Timea and Batmanov, Alisher and Barschkett, Mara and Basdil, B. Kaan and Dower, Jaromneda and Castek, Ondrej and Caviglia-Harris, Jill and Strand, Gabriella Chauca and Chen, Shi and Chzhen, Asya and Chung, Jong and Collins, Jason and Coppock, Alexander and Cordeau, Hugo and Couillard, Ben and Crechet, Jonathan and Crippa, Lorenzo and Cui, Jeanne and Czymara, Christian and Daarstad, Haley and Dao, Danh Chi and Dao, Dong and Schmandt, Marco David and Linde, Astrid de and Melo, Lucas De and Deer, Lachlan and Vera, Micole De and Dimitrova, Velichka and Dollbaum, Jan Fabian and Dollbaum, Jan Matti and Donnelly, Michael and Huynh, Luu Duc Toan and Dumbalska, Tsvetomira and Duncan, Jamie and Duong, Kiet Tuan and Duprey, Thibaut and Dworschak, Christoph and Ellingsrud, Sigmund and Elminejad, Ali and Eissa, Yasmine and Erhart, Andrea and Etingin-Frati, Giulian and Fatemi-Pour, Elaheh and Federice, Alexa and Feld, Jan and Fenig, Guidon and Firouzjaeiangalougah, Mojtaba and Fleisje, Erlend and Fortier-Chouinard, Alexandre and Engel, Julia Francesca and Fries, Tilman and Fortier, Reid and Fr{\´e}chet, Nadjim and Galipeau, Thomas and Gallegos, Sebasti{\´a}n and Gangji, Areez and Gao, Xiaoying and Garnache, Clo{\´e} and G{\´a}sp{\´a}r, Attila and Gavrilova, Evelina and Ghosh, Arijit and Gibney, Garreth and Gibson, Grant and Godager, Geir and Goff, Leonard and Gong, Da and Gonz{\´a}lez, Javier and Gretton, Jeremy and Griffa, Cristina and Grigoryeva, Idaliya and Grtting, Maja and Guntermann, Eric and Guo, Jiaqi and Gugushvili, Alexi and Habibnia, Hooman and H{\"a}ffner, Sonja and Hall, Jonathan D. and Hammar, Olle and Kordt, Amund Hanson and Hashimoto, Barry and Hartley, Jonathan S. and Hausladen, Carina I. and Havr{\´a}nek, Tom{\´a}š and Hazen, Jacob and He, Harry and Hepplewhite, Matthew and Herrera-Rodriguez, Mario and Heuer, Felix and Heyes, Anthony and Ho, Anson T. Y. and Holmes, Jonathan and Holzknecht, Armando and Hsu, Yu-Hsiang Dexter and Hu, Shiang-Hung and Huang, Yu-Shiuan and Huebener, Mathias and Huber, Christoph and Huynh, Kim P. and Irsova, Zuzana and Isler, Ozan and Jakobsson, Niklas and Frith, Michael James and Jananji, Rapha{\"e}l and Jayalath, Tharaka A. and Jetter, Michael and John, Jenny and Forshaw, Rachel Joy and Juan, Felipe and Kadriu, Valon and Karim, Sunny and Kelly, Edmund and Dang, Duy Khanh Hoang and Khushboo, Tazia and Kim, Jin and Kjellsson, Gustav and Kjelsrud, Anders and Kotsadam, Andreas and Korpershoek, Jori and Krashinsky, Lewis and Kundu, Suranjana and Kustov, Alexander and Lalayev, Nurlan and Langlois, Audr{\´e}e and Laufer, Jill and Lee-Whiting, Blake and Leibing, Andreas and Lenz, Gabriel and Levin, Joel and Li, Peng and Li, Tongzhe and Lin, Yuchen and Listo, Ariel and Liu, Dan and Lu, Xuewen and Lukmanova, Elvina and Luscombe, Alex and Lusher, Lester R. and Lyu, Ke and Ma, Hai and M{\"a}der, Nicolas and Makate, Clifton and Malmberg, Alice and Maitra, Adit and Mandas, Marco and Marcus, Jan and Margaryan, Shushanik and M{\´a}rk, Lili and Martignano, Andres and Marsh, Abigail and Masetto, Isabella and McCanny, Anthony and McManus, Emma and McWay, Ryan and Metson, Lennard and Kinge, Jonas Minet and Mishra, Sumit and Mohnen, Myra and M{\"o}ller, Jakob and Montambeault, Rosalie and Montpetit, S{\´e}bastien and Morin, Louis-Philippe and Morris, Todd and Moser, Scott and Motoki, Fabio and Muehlenbachs, Lucija and Musulan, Andreea and Musumeci, Marco and Nabin, Munirul and Nchare, Karim and Neubauer, Florian and Nguyen, Quan M. P. and Nguyen, Tuan and Nguyen-Tien, Viet and Niazi, Ali and Nikolaishvili, Giorgi and Nordstrom, Ardyn and N{\"u}, Patrick and Odermatt, Angela and Olson, Matt and ien, Henning and {\"O}lkers, Tim and Vert, Miquel Oliver i. and Oral, Emre and Oswald, Christian and Ousman, Ali and {\"O}zak, {\"O}mer and Pandey, Shubham and Pavlov, Alexandre and Pelli, Martino and Penheiro, Romeo and Park, RyuGyung and Martel, Eva P{\´e}rez and Petrovičov{\´a}, Tereza and Phan, Linh and Prettyman, Alexa and Proch{\´a}zka, Jakub and Putri, Aqila and Quandt, Julian and Qiu, Kangyu and Nguyen, Loan Quynh Thi and Rahman, Andaleeb and Rea, Carson H. and Reiremo, Adam and Ren{\´e}e, La{\"e}titia and Richardson, Joseph and Rivers, Nicholas and Rodrigues, Bruno and Roelofs, William and Roemer, Tobias and Rogeberg, Ole and Rose, Julian and Roskos-Ewoldsen, Andrew and Rosmer, Paul and Sabada, Barbara and Saberian, Soodeh and Salamanca, Nicolas and Sator, Georg and Sawyer, Antoine and Scates, Daniel and Schl{\"u}ter, Elmar and Sells, Cameron and Sen, Sharmi and Sethi, Ritika and Shcherbiak, Anna and Sogaolu, Moyosore and Soosalu, Matt and Srensen, Erik and Sovani, Manali and Spencer, Noah and Staubli, Stefan and Stans, Renske and Stewart, Anya and Stips, Felix and Stockley, Kieran and Strobel, Stephenson and Struby, Ethan and Tang, John and Tanrisever, Idil and Yang, Thomas Tao and Tastan, Ipek and Tatić, Dejan and Tatlow, Benjamin and Seuyong, F{\´e}raud Tchuisseu and Th{\´e}riault, R{\´e}mi and Thivierge, Vincent and Tian, Wenjie and Toma, Filip-Mihai and Totarelli, Maddalena and Tran, Van-Anh and Truong, Hung and Tsoy, Nikita and Tuzcuoglu, Kerem and Ubfal, Diego and Villalobos, Laura and Walterskirchen, Julian and Wang, Joseph Taoyi and Wattal, Vasudha and Webb, Matthew D. and Weber, Bryan and Weisser, Reinhard and Weng, Wei-Chien and Westheide, Christian and White, Kimberly and Winter, Jacob and Wochner, Timo and Woerman, Matt and Wong, Jared and Woodard, Ritchie and Wroński, Marcin and Yazbeck, Myra and Yang, Gustav Chung and Yap, Luther and Yassin, Kareman and Ye, Hao and Yoon, Jin Young and Yurris, Chris and Zahra, Tahreen and Zaneva, Mirela and Zayat, Aline and Zhang, Jonathan and Zhao, Ziwei and Yaolang, Zhong},
title = {Mass reproducibility and replicability},
series = {I4R discussion paper series},
journal = {I4R discussion paper series},
number = {107},
publisher = {Institute for Replication},
address = {Essen},
issn = {2752-1931},
pages = {250},
year = {2024},
abstract = {This study pushes our understanding of research reliability by reproducing and replicating claims from 110 papers in leading economic and political science journals. The analysis involves computational reproducibility checks and robustness assessments. It reveals several patterns. First, we uncover a high rate of fully computationally reproducible results (over 85\%). Second, excluding minor issues like missing packages or broken pathways, we uncover coding errors for about 25\% of studies, with some studies containing multiple errors. Third, we test the robustness of the results to 5,511 re-analyses. We find a robustness reproducibility of about 70\%. Robustness reproducibility rates are relatively higher for re-analyses that introduce new data and lower for re-analyses that change the sample or the definition of the dependent variable. Fourth, 52\% of re-analysis effect size estimates are smaller than the original published estimates and the average statistical significance of a re-analysis is 77\% of the original. Lastly, we rely on six teams of researchers working independently to answer eight additional research questions on the determinants of robustness reproducibility. Most teams find a negative relationship between replicators' experience and reproducibility, while finding no relationship between reproducibility and the provision of intermediate or even raw data combined with the necessary cleaning codes.},
language = {en}
}
@article{LuoChenZengetal.2018,
author = {Luo, Ting and Chen, Xiaoyi and Zeng, Shufei and Guan, Baozhang and Hu, Bo and Meng, Yu and Liu, Fanna and Wong, Taksui and Lu, Yongpin and Yun, Chen and Hocher, Berthold and Yin, Lianghong},
title = {Bioinformatic identification of key genes and analysis of prognostic values in clear cell renal cell carcinoma},
series = {Oncology Letters},
volume = {16},
journal = {Oncology Letters},
number = {2},
publisher = {Spandidos publ LTD},
address = {Athens},
issn = {1792-1074},
doi = {10.3892/ol.2018.8842},
pages = {1747 -- 1757},
year = {2018},
abstract = {The present study aimed to identify new key genes as potential biomarkers for the diagnosis, prognosis or targeted therapy of clear cell renal cell carcinoma (ccRCC). Three expression profiles (GSE36895, GSE46699 and GSE71963) were collected from Gene Expression Omnibus. GEO2R was used to identify differentially expressed genes (DEGs) in ccRCC tissues and normal samples. The Database for Annotation, Visualization and Integrated Discovery was utilized for functional and pathway enrichment analysis. STRING v10.5 and Molecular Complex Detection were used for protein-protein interaction (PPI) network construction and module analysis, respectively. Regulation network analyses were performed with the WebGestal tool. UALCAN web-portal was used for expression validation and survival analysis of hub genes in ccRCC patients from The Cancer Genome Atlas (TCGA). A total of 65 up- and 164 downregulated genes were identified as DEGs. DEGs were enriched with functional terms and pathways compactly related to ccRCC pathogenesis. Seventeen hub genes and one significant module were filtered out and selected from the PPI network. The differential expression of hub genes was verified in TCGA patients. Kaplan-Meier plot showed that high mRNA expression of enolase 2 (ENO2) was associated with short overall survival in ccRCC patients (P=0.023). High mRNA expression of cyclin D1 (CCND1) (P<0.001), fms related tyrosine kinase 1 (FLT1) (P=0.004), plasminogen (PLG) (P<0.001) and von Willebrand factor (VWF) (P=0.008) appeared to serve as favorable factors in survival. These findings indicate that the DEGs may be key genes in ccRCC pathogenesis and five genes, including ENO2, CCND1, PLT1, PLG and VWF, may serve as potential prognostic biomarkers in ccRCC.},
language = {en}
}
@article{ChenWangWangetal.2014,
author = {Chen, Yao and Wang, Guang and Wang, Xiao-yu and Ma, Zheng-lai and Chen, You-peng and Chuai, Manli and von Websky, Karoline and Hocher, Berthold and Yang, Xuesong},
title = {Effects of high salt-exposure on the development of retina and lens in 5.5-Day Chick Embryo},
series = {Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology},
volume = {34},
journal = {Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology},
number = {3},
publisher = {Karger},
address = {Basel},
issn = {1015-8987},
doi = {10.1159/000363044},
pages = {804 -- 817},
year = {2014},
abstract = {Background/Aims: Excess maternal salt intake during pregnancy may alter fetal development. However; our knowledge on how an increased salt intake during pregnancy influences fetal eye development is limited. In this study, we investigated the effects of high salt treatment on the developing eyes in chick embryos, especially focusing on the development of the retina and the lens. Methods: 5.5 day chick embryos were exposed to 280mosm/l (n=17), or 300mosm/l (n=16) NaCl. The treated embryos were then incubated for 96 hours before they were fixed with 4\% paraformaldehyde for H\&E staining, whole mount embryo immunostaining and TUNEL staining. BrdU and PH3 incorporation experiments were performed on the chick embryos after high salt treatment. RT-PCR analyses were conducted from chick retina tissues. Results: We demonstrated that high-salt treatment altered the size of eyes in chick embryos, induced malformation of the eyes and impaired the development of the lens and the retina. We found an impaired expression of Paired box 6 (PAX6) and neuronal cells in the developing retina as revealed by neurofilament immunofluorescent staining. There was a reduction in the number of BrdU-positive cells and PH3-positive cells in the retina, indicating an impaired cell proliferation with high salt treatment. High salt treatment also resulted in an increased number of TUNEL-positive cells in the retina, indicating a higher amount of cell death. RT-PCR data displayed that the expression of the pro-apoptotic molecule nerve growth factor (NGF) in chick retina was increased and CyclinD1 was reduced with high-salt treatment. The size of the lens was reduced and Pax6 expression in the lens was significantly inhibited. High salt treatment was detrimental to the migration of neural crest cells. Conclusion: Taken together; our study demonstrated that high salt exposure of 5.5 day chick embryos led to an impairment of retina and lens development, possibly through interfering with Pax6 expression.},
language = {en}
}
@article{AleksicAnsoldiAntonellietal.2015,
author = {Aleksic, J. and Ansoldi, S. and Antonelli, L. A. and Antoranz, P. and Babic, A. and Bangale, P. and de Almeida, U. Barres and Barrio, J. A. and Becerra Gonzalez, J. and Bednarek, W. and Berger, K. and Bernardini, E. and Biland, A. and Blanch Bigas, O. and Bock, R. K. and Bonnefoy, S. and Bonnoli, G. and Borracci, F. and Bretz, T. and Carmona, E. and Carosi, A. and Fidalgo, D. Carreto and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Da Vela, P. and Dazzi, F. and De Angelis, A. and De Caneva, G. and De Lotto, B. and Delgado Mendez, C. and Doert, M. and Dominguez, A. and Prester, Dijana Dominis and Dorner, D. and Doro, M. and Einecke, S. and Eisenacher, D. and Elsaesser, D. and Farina, E. and Ferenc, D. and Fonseca, M. V. and Font, L. and Frantzen, K. and Fruck, C. and Garcia Lopez, R. J. and Garczarczyk, M. and Garrido Terrats, D. and Gaug, M. and Giavitto, G. and Godinovic, N. and Gonzalez Munoz, A. and Gozzini, S. R. and Hadamek, A. and Hadasch, D. and Herrero, A. and Hildebrand, D. and Hose, J. and Hrupec, D. and Idec, W. and Kadenius, V. and Kellermann, H. and Knoetig, M. L. and Krause, J. and Kushida, J. and La Barbera, A. and Lelas, D. and Lewandowska, N. and Lindfors, E. and Lombardi, S. and Lopez, M. and Lopez-Coto, R. and Lopez-Oramas, A. and Lorenz, E. and Lozano, I. and Makariev, M. and Mallot, K. and Maneva, G. and Mankuzhiyil, N. and Mannheim, K. and Maraschi, L. and Marcote, B. and Mariotti, M. and Martinez, M. and Mazin, D. and Menzel, U. and Meucci, M. and Miranda, J. M. and Mirzoyan, R. and Moralejo, A. and Munar-Adrover, P. and Nakajima, D. and Niedzwiecki, A. and Nilsson, K. and Nowak, N. and Orito, R. and Overkemping, A. and Paiano, S. and Palatiello, M. and Paneque, D. and Paoletti, R. and Paredes, J. M. and Paredes-Fortuny, X. and Partini, S. and Persic, M. and Prada, F. and Moroni, P. G. Prada and Prandini, E. and Preziuso, S. and Puljak, I. and Reinthal, R. and Rhode, W. and Ribo, M. and Rico, J. and Garcia, J. Rodriguez and Ruegamer, S. and Saggion, A. and Saito, T. and Saito, K. and Salvati, M. and Satalecka, K. and Scalzotto, V. and Scapin, V. and Schultz, C. and Schweizer, T. and Shore, S. N. and Sillanpaa, A. and Sitarek, J. and Snidaric, I. and Sobczynska, D. and Spanier, F. and Stamatescu, V. and Stamerra, A. and Steinbring, T. and Storz, J. and Sun, S. and Suric, T. and Takalo, L. and Tavecchio, F. and Temnikov, P. and Terzic, T. and Tescaro, D. and Teshima, M. and Thaele, J. and Tibolla, O. and Torres, D. F. and Toyama, T. and Treves, A. and Uellenbeck, M. and Vogler, P. and Wagner, R. M. and Zandanel, F. and Zanin, R. and Behera, B. and Beilicke, M. and Benbow, W. and Berger, K. and Bird, R. and Bouvier, A. and Bugaev, V. and Cerruti, M. and Chen, Xuhui and Ciupik, L. and Collins-Hughes, E. and Cui, W. and Duke, C. and Dumm, J. and Falcone, A. and Federici, Simone and Feng, Q. and Finley, J. P. and Fortson, L. and Furniss, A. and Galante, N. and Gillanders, G. H. and Griffin, S. and Griffiths, S. T. and Grube, J. and Gyuk, G. and Hanna, D. and Holder, J. and Johnson, C. A. and Kaaret, P. and Kertzman, M. and Kieda, D. and Krawczynski, H. and Lang, M. J. and Madhavan, A. S. and Maier, G. and Majumdar, P. and Meagher, K. and Moriarty, P. and Mukherjee, R. and Nieto, D. and Ong, R. A. and Otte, A. N. and Pichel, A. and Pohl, Manula and Popkow, A. and Prokoph, H. and Quinn, J. and Rajotte, J. and Ratliff, G. and Reyes, L. C. and Reynolds, P. T. and Richards, G. T. and Roache, E. and Sembroski, G. H. and Shahinyan, K. and Sheidaei, F. and Smith, A. W. and Staszak, D. and Telezhinsky, Igor O. and Theiling, M. and Tyler, J. and Varlotta, A. and Vincent, S. and Wakely, S. P. and Weekes, T. C. and Welsing, R. and Williams, D. A. and Zajczyk, A. and Zitzer, B. and Villata, M. and Raiteri, C. M. and Ajello, M. and Perri, M. and Aller, H. D. and Aller, M. F. and Larionov, V. M. and Efimova, N. V. and Konstantinova, T. S. and Kopatskaya, E. N. and Chen, W. P. and Koptelova, E. and Hsiao, H. Y. and Kurtanidze, O. M. and Nikolashvili, M. G. and Kimeridze, G. N. and Jordan, B. and Leto, Paolo and Buemi, C. S. and Trigilio, C. and Umana, G. and Lahteenmaki, A. and Nieppola, E. and Tornikoski, M. and Sainio, J. and Kadenius, V. and Giroletti, M. and Cesarini, A. and Fuhrmann, L. and Kovalev, Yu. A. and Kovalev, Y. Y.},
title = {Multiwavelength observations of Mrk 501 in 2008},
series = {Astronomy and astrophysics : an international weekly journal},
volume = {573},
journal = {Astronomy and astrophysics : an international weekly journal},
publisher = {EDP Sciences},
address = {Les Ulis},
organization = {MAGIC Collaboration, VERITAS Collaboration},
issn = {0004-6361},
doi = {10.1051/0004-6361/201322906},
pages = {12},
year = {2015},
abstract = {Context. Blazars are variable sources on various timescales over a broad energy range spanning from radio to very high energy (>100 GeV, hereafter VHE). Mrk 501 is one of the brightest blazars at TeV energies and has been extensively studied since its first VHE detection in 1996. However, most of the gamma-ray studies performed on Mrk 501 during the past years relate to flaring activity, when the source detection and characterization with the available gamma-ray instrumentation was easier to perform. Aims. Our goal is to characterize the source gamma-ray emission in detail, together with the radio-to-X-ray emission, during the non-flaring (low) activity, which is less often studied than the occasional flaring (high) activity. Methods. We organized a multiwavelength (MW) campaign on Mrk 501 between March and May 2008. This multi-instrument effort included the most sensitive VHE gamma-ray instruments in the northern hemisphere, namely the imaging atmospheric Cherenkov telescopes MAGIC and VERITAS, as well as Swift, RXTE, the F-GAMMA, GASP-WEBT, and other collaborations and instruments. This provided extensive energy and temporal coverage of Mrk 501 throughout the entire campaign. Results. Mrk 501 was found to be in a low state of activity during the campaign, with a VHE flux in the range of 10\%-20\% of the Crab nebula flux. Nevertheless, significant flux variations were detected with various instruments, with a trend of increasing variability with energy and a tentative correlation between the X-ray and VHE fluxes. The broadband spectral energy distribution during the two different emission states of the campaign can be adequately described within the homogeneous one-zone synchrotron self-Compton model, with the (slightly) higher state described by an increase in the electron number density. Conclusions. The one-zone SSC model can adequately describe the broadband spectral energy distribution of the source during the two months covered by the MW campaign. This agrees with previous studies of the broadband emission of this source during flaring and non-flaring states. We report for the first time a tentative X-ray-to-VHE correlation during such a low VHE activity. Although marginally significant, this positive correlation between X-ray and VHE, which has been reported many times during flaring activity, suggests that the mechanisms that dominate the X-ray/VHE emission during non-flaring-activity are not substantially different from those that are responsible for the emission during flaring activity.},
language = {en}
}
@article{YangDingKochovskietal.2017,
author = {Yang, Guang and Ding, Hong-ming and Kochovski, Zdravko and Hu, Rongting and Lu, Yan and Ma, Yu-qiang and Chen, Guosong and Jiang, Ming},
title = {Highly Ordered Self-Assembly of Native Proteins into 1D, 2D, and 3D Structures Modulated by the Tether Length of Assembly-Inducing Ligands},
series = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition},
volume = {56},
journal = {Angewandte Chemie : a journal of the Gesellschaft Deutscher Chemiker ; International edition},
publisher = {Wiley-VCH},
address = {Weinheim},
issn = {1433-7851},
doi = {10.1002/anie.201703052},
pages = {10691 -- 10695},
year = {2017},
abstract = {In nature, proteins self-assemble into various structures with different dimensions. To construct these nanostructures in laboratories, normally proteins with different symmetries are selected. However, most of these approaches are engineering-intensive and highly dependent on the accuracy of the protein design. Herein, we report that a simple native protein LecA assembles into one-dimensional nanoribbons and nanowires, two-dimensional nanosheets, and three-dimensional layered structures controlled mainly by small-molecule assembly-inducing ligands RnG (n = 1, 2, 3, 4, 5) with varying numbers of ethylene oxide repeating units. To understand the formation mechanism of the different morphologies controlled by the small-molecule structure, molecular simulations were performed from microscopic and mesoscopic view, which presented a clear relationship between the molecular structure of the ligands and the assembled patterns. These results introduce an easy strategy to control the assembly structure and dimension, which could shed light on controlled protein assembly.},
language = {en}
}
@article{XiangGaoCaietal.2017,
author = {Xiang, Hai and Gao, Jianqiang and Cai, Dawei and Luo, Yunbing and Yu, Baoquan and Liu, Langqing and Liu, Ranran and Zhou, Hui and Chen, Xiaoyong and Dun, Weitao and Wang, Xi and Hofreiter, Michael and Zhao, Xingbo},
title = {Origin and dispersal of early domestic pigs in northern China},
series = {Scientific reports},
volume = {7},
journal = {Scientific reports},
publisher = {Nature Publ. Group},
address = {London},
issn = {2045-2322},
doi = {10.1038/s41598-017-06056-8},
pages = {9},
year = {2017},
abstract = {It is widely accepted that modern pigs were domesticated independently at least twice, and Chinese native pigs are deemed as direct descendants of the first domesticated pigs in the corresponding domestication centers. By analyzing mitochondrial DNA sequences of an extensive sample set spanning 10,000 years, we find that the earliest pigs from the middle Yellow River region already carried the maternal lineages that are dominant in both younger archaeological populations and modern Chinese pigs. Our data set also supports early Neolithic pig utilization and a long-term in situ origin for northeastern Chinese pigs during 8,000-3,500 BP, suggesting a possibly independent domestication in northeast China. Additionally, we observe a genetic replacement in ancient northeast Chinese pigs since 3,500 BP. The results not only provide increasing evidence for pig origin in the middle Yellow River region but also depict an outline for the process of early pig domestication in northeast China.},
language = {en}
}
@article{AbdoAckermannAjelloetal.2011,
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B. and Fortin, P. and Frailis, M. and Fuhrmann, L. and Fukazawa, Y. and Funk, S. and Fusco, P. and Gargano, F. and Gasparrini, D. and Gehrels, N. and Germani, S. and Giglietto, N. and Giordano, F. and Giroletti, M. and Glanzman, T. and Godfrey, G. and Grenier, I. A. and Guillemot, L. and Guiriec, S. and Hayashida, M. and Hays, E. and Horan, D. and Hughes, R. E. and Johannesson, G. and Johnson, A. S. and Johnson, W. N. and Kadler, M. and Kamae, T. and Katagiri, H. and Kataoka, J. and Knoedlseder, J. and Kuss, M. and Lande, J. and Latronico, L. and Lee, S. -H. and Lemoine-Goumard, M. and Longo, F. and Loparco, F. and Lott, B. and Lovellette, M. N. and Lubrano, P. and Madejski, G. M. and Makeev, A. and Max-Moerbeck, W. and Mazziotta, Mario Nicola and McEnery, J. E. and Mehault, J. and Michelson, P. F. and Mitthumsiri, W. and Mizuno, T. and Moiseev, A. A. and Monte, C. and Monzani, M. E. and Morselli, A. and Moskalenko, I. V. and Murgia, S. and Naumann-Godo, M. and Nishino, S. and Nolan, P. L. and Norris, J. P. and Nuss, E. and Ohsugi, T. and Okumura, A. and Omodei, N. and Orlando, E. and Ormes, J. F. and Paneque, D. and Panetta, J. H. and Parent, D. and Pavlidou, V. and Pearson, T. J. and Pelassa, V. and Pepe, M. and Pesce-Rollins, M. and Piron, F. and Porter, T. A. and Raino, S. and Rando, R. and Razzano, M. and Readhead, A. and Reimer, A. and Reimer, O. and Richards, J. L. and Ripken, J. and Ritz, S. and Roth, M. and Sadrozinski, H. F. -W. and Sanchez, D. and Sander, A. and Scargle, J. D. and Sgro, C. and Siskind, E. J. and Smith, P. D. and Spandre, G. and Spinelli, P. and Stawarz, L. and Stevenson, M. and Strickman, M. S. and Sokolovsky, K. V. and Suson, D. J. and Takahashi, H. and Takahashi, T. and Tanaka, T. and Thayer, J. B. and Thayer, J. G. and Thompson, D. J. and Tibaldo, L. and Torres, F. and Tosti, G. and Tramacere, A. and Uchiyama, Y. and Usher, T. L. and Vandenbroucke, J. and Vasileiou, V. and Vilchez, N. and Vitale, V. and Waite, A. P. and Wang, P. and Wehrle, A. E. and Winer, B. L. and Wood, K. S. and Yang, Z. and Ylinen, T. and Zensus, J. A. and Ziegler, M. and Aleksic, J. and Antonelli, L. A. and Antoranz, P. and Backes, Michael and Barrio, J. A. and Gonzalez, J. Becerra and Bednarek, W. and Berdyugin, A. and Berger, K. and Bernardini, E. and Biland, A. and Blanch Bigas, O. and Bock, R. K. and Boller, A. and Bonnoli, G. and Bordas, Pol and Tridon, D. Borla and Bosch-Ramon, Valentin and Bose, D. and Braun, I. and Bretz, T. and Camara, M. and Carmona, E. and Carosi, A. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Dazzi, F. and de Angelis, A. and del Pozo, E. De Cea and De Lotto, B. and De Maria, M. and De Sabata, F. and Mendez, C. Delgado and Ortega, A. 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W. and Mori, Y. and Nestoras, I. and Orlati, A. and Pagani, C. and Pace, C. and Pearson, R. and Perri, M. and Piner, B. G. and Pushkarev, A. B. and Ros, E. and Sadun, A. C. and Sakamoto, T. and Tornikoski, M. and Yatsu, Y. and Zook, A.},
title = {Insights into the high-energy gamma-Ray emission of markarian 501 fromextensive multifrequency observations in the fermi era},
series = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
volume = {727},
journal = {The astrophysical journal : an international review of spectroscopy and astronomical physics},
number = {2},
publisher = {IOP Publ. Ltd.},
address = {Bristol},
organization = {Fermi-LAT Collaboration, MAGIC Collaboration, VERITAS Collaboration},
issn = {0004-637X},
doi = {10.1088/0004-637X/727/2/129},
pages = {26},
year = {2011},
abstract = {We report on the gamma-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) gamma-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 +/- 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 +/- 0.14, and the softest one is 2.51 +/- 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15-August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size less than or similar to 0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (similar or equal to 10(44) erg s(-1)) constitutes only a small fraction (similar to 10(-3)) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude.},
language = {en}
}
@article{WartenbergBuddedeMareesetal.2003,
author = {Wartenberg, Maria and Budde, Paula and de Mare{\´e}s, M. and Tsang, S. Y. and Huang, Y. and Chen, Zhen-Yu and Hescheler, J{\"u}rgen and Sauer, Heinrich},
title = {Inhibition of tumor-induced angiogenesis and matrix-metalloproteinase expression in confrontation cultures of ES cell-derived embryoid bodies and multicellular tumor spheroids by plant ingredients use},
year = {2003},
language = {en}
}
@article{AhnenAnsoldiAntonellietal.2017,
author = {Ahnen, M. L. and Ansoldi, S. and Antonelli, L. A. and Antoranz, P. and Babic, A. and Banerjee, B. and Bangale, P. and de Almeida, U. Barres and Barrio, J. A. and Gonzalez, J. Becerra and Bednarek, W. and Bernardini, E. and Berti, A. and Biasuzzi, B. and Biland, A. and Blanch, O. and Bonnefoy, S. and Bonnoli, G. and Borracci, F. and Bretz, T. and Buson, S. and Carosi, A. and Chatterjee, A. and Clavero, R. and Colin, P. and Colombo, E. and Contreras, J. L. and Cortina, J. and Covino, S. and Da Vela, P. and Dazzi, F. and De Angelis, A. and De Lotto, B. and Wilhelmi, E. de Ona and Di Pierro, F. and Doert, M. and Dominguez, A. and Prester, D. Dominis and Dorner, D. and Doro, M. and Einecke, S. and Glawion, D. Eisenacher and Elsaesser, D. and Engelkemeier, M. and Ramazani, V. Fallah and Fernandez-Barral, A. and Fidalgo, D. and Fonseca, M. V. and Font, L. and Frantzen, K. and Fruck, C. and Galindo, D. and Lopez, R. J. Garcia and Garczarczyk, M. and Terrats, D. Garrido and Gaug, M. and Giammaria, P. and Godinovic, N. and Gonzalez Munoz, A. and Gora, D. and Guberman, D. and Hadasch, D. and Hahn, A. and Hanabata, Y. and Hayashida, M. and Herrera, J. and Hose, J. and Hrupec, D. and Hughes, G. and Idec, W. and Kodani, K. and Konno, Y. and Kubo, H. and Kushida, J. and La Barbera, A. and Lelas, D. and Lindfors, E. and Lombardi, S. and Longo, F. and Lopez, M. and Lopez-Coto, R. and Majumdar, P. and Makariev, M. and Mallot, K. and Maneva, G. and Manganaro, M. and Mannheim, K. and Maraschi, L. and Marcote, B. and Mariotti, M. and Martinez, M. and Mazin, D. and Menzel, U. and Miranda, J. M. and Mirzoyan, R. and Moralejo, A. and Moretti, E. and Nakajima, D. and Neustroev, V. and Niedzwiecki, A. and Rosillo, M. Nievas and Nilsson, K. and Nishijima, K. and Noda, K. and Nogues, L. and Overkemping, A. and Paiano, S. and Palacio, J. and Palatiello, M. and Paneque, D. and Paoletti, R. and Paredes, J. M. and Paredes-Fortuny, X. and Pedaletti, G. and Peresano, M. and Perri, L. and Persic, M. and Poutanen, J. and Moroni, P. G. Prada and Prandini, E. and Puljak, I. and Reichardt, I. and Rhode, W. and Ribo, M. and Rico, J. and Rodriguez Garcia, J. and Saito, T. and Satalecka, K. and Schroder, S. and Schultz, C. and Schweizer, T. and Shore, S. N. and Sillanpaa, A. and Sitarek, J. and Snidaric, I. and Sobczynska, D. and Stamerra, A. and Steinbring, T. and Strzys, M. and Suric, T. and Takalo, L. and Tavecchio, F. and Temnikov, P. and Terzic, T. and Tescaro, D. and Teshima, M. and Thaele, J. and Torres, D. F. and Toyama, T. and Treves, A. and Vanzo, G. and Verguilov, V. and Vovk, I. and Ward, J. E. and Will, M. and Wu, M. H. and Zanin, R. and Abeysekara, A. U. and Archambault, S. and Archer, A. and Benbow, W. and Bird, R. and Buchovecky, M. and Buckley, J. H. and Bugaev, V. and Connolly, M. P. and Cui, W. and Dickinson, H. J. and Falcone, A. and Feng, Q. and Finley, J. P. and Fleischhack, H. and Flinders, A. and Fortson, L. and Gillanders, G. H. and Griffin, S. and Grube, J. and Huetten, M. and Hanna, D. and Holder, J. and Humensky, T. B. and Kaaret, P. and Kar, P. and Kelley-Hoskins, N. and Kertzman, M. and Kieda, D. and Krause, M. and Krennrich, F. and Lang, M. J. and Maier, G. and McCann, A. and Moriarty, P. and Mukherjee, R. and Nieto, D. and Ong, R. A. and Otte, N. and Park, N. and Perkins, J. and Pichel, A. and Pohl, M. and Popkow, A. and Pueschel, Elisa and Quinn, J. and Ragan, K. and Reynolds, P. T. and Richards, G. T. and Roache, E. and Rovero, A. C. and Rulten, C. and Sadeh, I. and Santander, M. and Sembroski, G. H. and Shahinyan, K. and Telezhinsky, Igor O. and Tucci, J. V. and Tyler, J. and Wakely, S. P. and Weinstein, A. and Wilcox, P. and Wilhelm, Alina and Williams, D. A. and Zitzer, B. and Razzaque, S. and Villata, M. and Raiteri, C. M. and Aller, H. D. and Aller, M. F. and Larionov, V. M. and Arkharov, A. A. and Blinov, D. A. and Efimova, N. V. and Grishina, T. S. and Hagen-Thorn, V. A. and Kopatskaya, E. N. and Larionova, L. V. and Larionova, E. G. and Morozova, D. A. and Troitsky, I. S. and Ligustri, R. and Calcidese, P. and Berdyugin, A. and Kurtanidze, O. M. and Nikolashvili, M. G. and Kimeridze, G. N. and Sigua, L. A. and Kurtanidze, S. O. and Chigladze, R. A. and Chen, W. P. and Koptelova, E. and Sakamoto, T. and Sadun, A. C. and Moody, J. W. and Pace, C. and Pearson, R. and Yatsu, Y. and Mori, Y. and Carraminyana, A. and Carrasco, L. and de la Fuente, E. and Norris, J. P. and Smith, P. S. and Wehrle, A. and Gurwell, M. A. and Zook, A. and Pagani, C. and Perri, M. and Capalbi, M. and Cesarini, A. and Krimm, H. A. and Kovalev, Y. Y. and Kovalev, Yu. A. and Ros, E. and Pushkarev, A. B. and Lister, M. L. and Sokolovsky, K. V. and Kadler, M. and Piner, G. and Lahteenmaki, A. and Tornikoski, M. and Angelakis, E. and Krichbaum, T. P. and Nestoras, I. and Fuhrmann, L. and Zensus, J. A. and Cassaro, P. and Orlati, A. and Maccaferri, G. and Leto, P. and Giroletti, M. and Richards, J. L. and Max-Moerbeck, W. and Readhead, A. C. S.},
title = {Multiband variability studies and novel broadband SED modeling of Mrk 501 in 2009},
series = {Astronomy and astrophysics : an international weekly journal},
volume = {603},
journal = {Astronomy and astrophysics : an international weekly journal},
publisher = {EDP Sciences},
address = {Les Ulis},
organization = {MAGIC Collaboration;VERITAS Collaboration},
issn = {1432-0746},
doi = {10.1051/0004-6361/201629540},
pages = {30},
year = {2017},
abstract = {Aims. We present an extensive study of the BL Lac object Mrk 501 based on a data set collected during the multi-instrument campaign spanning from 2009 March 15 to 2009 August 1, which includes, among other instruments, MAGIC, VERITAS, Whipple 10 m, and Fermi-LAT to cover the gamma-ray range from 0.1 GeV to 20 TeV; RXTE and Swift to cover wavelengths from UV to hard X-rays; and GASP-WEBT, which provides coverage of radio and optical wavelengths. Optical polarization measurements were provided for a fraction of the campaign by the Steward and St. Petersburg observatories. We evaluate the variability of the source and interband correlations, the gamma-ray flaring activity occurring in May 2009, and interpret the results within two synchrotron self-Compton (SSC) scenarios. Methods. The multiband variability observed during the full campaign is addressed in terms of the fractional variability, and the possible correlations are studied by calculating the discrete correlation function for each pair of energy bands where the significance was evaluated with dedicated Monte Carlo simulations. The space of SSC model parameters is probed following a dedicated grid-scan strategy, allowing for a wide range of models to be tested and offering a study of the degeneracy of model-to-data agreement in the individual model parameters, hence providing a less biased interpretation than the "single-curve SSC model adjustment" typically reported in the literature. Results. We find an increase in the fractional variability with energy, while no significant interband correlations of flux changes are found on the basis of the acquired data set. The SSC model grid-scan shows that the flaring activity around May 22 cannot be modeled adequately with a one-zone SSC scenario (using an electron energy distribution with two breaks), while it can be suitably described within a two (independent) zone SSC scenario. Here, one zone is responsible for the quiescent emission from the averaged 4.5-month observing period, while the other one, which is spatially separated from the first, dominates the flaring emission occurring at X-rays and very-high-energy (> 100 GeV, VHE) gamma-rays. The flaring activity from May 1, which coincides with a rotation of the electric vector polarization angle (EVPA), cannot be satisfactorily reproduced by either a one-zone or a two-independent-zone SSC model, yet this is partially affected by the lack of strictly simultaneous observations and the presence of large flux changes on sub-hour timescales (detected at VHE gamma rays). Conclusions. The higher variability in the VHE emission and lack of correlation with the X-ray emission indicate that, at least during the 4.5-month observing campaign in 2009, the highest energy (and most variable) electrons that are responsible for the VHE gamma rays do not make a dominant contribution to the similar to 1 keV emission. Alternatively, there could be a very variable component contributing to the VHE gamma-ray emission in addition to that coming from the SSC scenario. The studies with our dedicated SSC grid-scan show that there is some degeneracy in both the one-zone and the two-zone SSC scenarios probed, with several combinations of model parameters yielding a similar model-to-data agreement, and some parameters better constrained than others. The observed gamma-ray flaring activity, with the EVPA rotation coincident with the first gamma-ray flare, resembles those reported previously for low frequency peaked blazars, hence suggesting that there are many similarities in the flaring mechanisms of blazars with different jet properties.},
language = {en}
}
@article{YuKoflerHaeusleretal.2001,
author = {Yu, Tien-Shin and Kofler, Heike and H{\"a}usler, Rainer E. and Hille, Diana and Fl{\"u}gge, Ulf-Ingo and Zeeman, Samuel C. and Smith, Alison M. and Kossmann, Jens and Lloyd, James R. and Ritte, Gerhard and Steup, Martin and Lue, Wei-Ling and Chen, Jychian and Weber, Andreas P. M.},
title = {The Arabidopsis sex1 mutant is defective in the R1 protein, a general regulator of starch degradation in plants, and not in the chloroplast hexose transporter},
issn = {1040-4651},
year = {2001},
language = {en}
}
@article{ZhouChenDongetal.2015,
author = {Zhou, Xiqiang and Chen, Daizhao and Dong, Shaofeng and Zhang, Yanqiu and Guo, Zenghui and Wei, Hengye and Yu, Hao},
title = {Diagenetic barite deposits in the Yurtus Formation in Tarim Basin, NW China: Implications for barium and sulfur cycling in the earliest Cambrian},
series = {Precambrian research},
volume = {263},
journal = {Precambrian research},
publisher = {Elsevier},
address = {Amsterdam},
issn = {0301-9268},
doi = {10.1016/j.precamres.2015.03.006},
pages = {79 -- 87},
year = {2015},
abstract = {Barite concretions and bands are widely distributed in black shale-chert horizons in the Yurtus Formation of Lower Cambrian in Aksu area, northwestern Tarim Basin, NW China. They mainly consist of coarse-grained anhedral to euhedral barite crystals with minor dolomites and pyrites. Petrological features indicate these concretions grew from the porewater in unconsolidated sediments at shallow burial below sediment-water interface. The slight deviation of Sr-87/Sr-86 ratios (0.7083 to 0.7090) and significant elevated delta S-34 values (56.8-76.4 parts per thousand CDT) of barite samples with respect to those of the Early Cambrian seawater further support that barite deposits precipitated from the enclosed porewater in sediment column, which evolved from the penecontemporaneous seawater with weak interaction with the host fine-grained siliciclastic sediments and highly-depleted sulfate in response to prolonged strong bacterial sulfate reduction without necessary renewal. The abundant organic matters in the basal Yurtus Formation should have facilitated developing sulfate-depleted methanogenesis zone and sulfate-methane transition zone (SMTZ) slightly after deposition. Therefore, barite deposits in the Yurtus Formation most likely resulted from diagenetic barium cycling and persistently grew from the porewater in the static SMTZ with a low sedimentation rate in the Early Cambrian. In comparison with the distribution of sedimentary barites in geological records, we tentatively proposed that a transition in diagenetic barium cycling and associated mineralization may have occurred from the Precambrian to Cambrian periods; this scenario may be causally linked to the changes in marine ecology (the advent of mesozooplankton and associated faecal pellet) and geochemistry (the increase of seawater sulfate concentration). Thus, the occurrence of diagenetic barite deposits in the Yurtus Formation implies that diagenetic barium cycling and more effective scavenging of barium from CH4- and Ba-rich porewaters within sediments might have become an nonnegligible process in continental margin areas, at least, since the earliest Cambrian, which could have significantly impacted the marine barium cycling. (C) 2015 Elsevier B.V. All rights reserved.},
language = {en}
}
@article{LiChenDongetal.2014,
author = {Li, Jian and Chen, You-Peng and Dong, Yun-Peng and Yu, Cal-Hong and Lu, Yong-Ping and Xiao, Xiao-Min and Hocher, Berthold},
title = {The impact of umbilical blood flow regulation on fetal development differs in diabetic and non-diabetic pregnancy},
series = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie},
volume = {39},
journal = {Kidney \& blood pressure research : official organ of the Gesellschaft f{\"u}r Nephrologie},
number = {4},
publisher = {Karger},
address = {Basel},
issn = {1420-4096},
doi = {10.1159/000355815},
pages = {369 -- 377},
year = {2014},
abstract = {Background/Aims: Diabetes is well-known to influence endothelial function. Endothelial function and blood flow regulation might be different in diabetic and non-diabetic pregnancy. However, the impact of umbilical blood flow regulation in gestational diabetes on fetal development is unknown so far. Methods: In a prospective birth cohort study, we analyzed the association of the umbilical artery Doppler indices (pulsatility index, resistance index and systolic/diastolic ratio) and fetal size measures (biparietal diameter, head circumference, abdominal circumference, femur length and birth weight) in 519 non-gestational diabetes mellitus pregnancies (controls) and 226 gestational diabetes mellitus pregnancies in middle (day 160.32 +/- 16.29 of gestation) and late (day 268.12 +/- 13.04 of gestation) pregnancy. Results: Multiple regression analysis considering confounding factors (gestational day of ultrasound examination, offspring sex, maternal body mess index before pregnancy, maternal age at delivery, maternal body weight at delivery and maternal hypertension) showed that umbilical artery Doppler indices (pulsatility index, resistance index and systolic/diastolic ratio) were associated with fetal head circumference and femur length in middle gestational diabetes mellitus pregnancy but not in non-gestational diabetes mellitus pregnancy. Head circumference, biparietal diameter, abdominal circumference and femur length in mid gestation were smaller in fetus of gestational diabetes mellitus pregnancy versus non-gestational diabetes mellitus pregnancy. In contrast to non-gestational diabetes mellitus pregnancy in late gestation, umbilical artery Doppler indices in gestational diabetes mellitus pregnancy were not associated with ultrasound measures of fetal growth. Birth weight was slightly increased in gestational diabetes mellitus pregnancy as compared to non-gestational diabetes mellitus pregnancy. Conclusions: The impact of umbilical blood flow on fetal growth is time dependent in human gestational diabetes mellitus and non-gestational diabetes mellitus pregnancy. In gestational diabetes mellitus pregnancy umbilical blood flow is critical for organ development in much earlier stages of pregnancy as compared to non-gestational diabetes mellitus pregnancy. The physiological and molecular pathways why there is a catch up growth in later times of gestational diabetes mellitus pregnancy resulting in larger gestational diabetes mellitus babies at birth needs to be addressed in further studies.},
language = {en}
}
@article{XiangGaoYuetal.2014,
author = {Xiang, Hai and Gao, Jianqiang and Yu, Baoquan and Zhou, Hui and Cai, Dawei and Zhang, Youwen and Chen, Xiaoyong and Wang, Xi and Hofreiter, Michael and Zhao, Xingbo},
title = {Early Holocene chicken domestication in northern China},
series = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {111},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
number = {49},
publisher = {National Acad. of Sciences},
address = {Washington},
issn = {0027-8424},
doi = {10.1073/pnas.1411882111},
pages = {17564 -- 17569},
year = {2014},
abstract = {Chickens represent by far the most important poultry species, yet the number, locations, and timings of their domestication have remained controversial for more than a century. Here we report ancient mitochondrial DNA sequences from the earliest archaeological chicken bones from China, dating back to similar to 10,000 B.P. The results clearly show that all investigated bones, including the oldest from the Nanzhuangtou site, are derived from the genus Gallus, rather than any other related genus, such as Phasianus. Our analyses also suggest that northern China represents one region of the earliest chicken domestication, possibly dating as early as 10,000 y B.P. Similar to the evidence from pig domestication, our results suggest that these early domesticated chickens contributed to the gene pool of modern chicken populations. Moreover, our results support the idea that multiple members of the genus Gallus, specifically Gallus gallus and Gallus sonneratii contributed to the gene pool of the modern domestic chicken. Our results provide further support for the growing evidence of an early mixed agricultural complex in northern China.},
language = {en}
}
@book{ChenYu2001,
author = {Chen, Hua and Yu, Chun},
title = {Asymptotic behaviour of the trace for schr{\"o}dinger operator on fractal drums},
series = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Mathematik, Arbeitsgruppe Partiell},
journal = {Preprint / Universit{\"a}t Potsdam, Institut f{\"u}r Mathematik, Arbeitsgruppe Partiell},
publisher = {Univ.},
address = {Potsdam},
issn = {1437-739X},
pages = {12 S.},
year = {2001},
language = {en}
}
@unpublished{ChenYu2001,
author = {Chen, Hua and Yu, Chun},
title = {Asymptotic behaviour of the trace for Schr{\"o}dinger operator on fractal drums},
url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-26157},
year = {2001},
language = {en}
}
@article{WangTiberiusChenetal.2021,
author = {Wang, Nan and Tiberius, Victor and Chen, Xiangxiang and Brem, Alexander and Yu, Fei},
title = {Idea selection and adoption by users},
series = {Technology analysis \& strategic management},
volume = {33},
journal = {Technology analysis \& strategic management},
number = {9},
publisher = {Taylor \& Francis Group},
address = {London},
issn = {0953-7325},
doi = {10.1080/09537325.2020.1863055},
pages = {1036 -- 1051},
year = {2021},
abstract = {Firms increasingly use ideas from online innovation communities to solve problems or to better address customer needs. However, in many cases the number of submitted ideas has exploded, it leads to an information overload that firms hardly can handle considering their limited cognitive resources. Therefore, we use the Elaboration Likelihood Model to distinguish between the quick and lean idea preselection process as a peripheral route of information processing and the subsequent idea review process as a central route of information processing. In our empirical study with a sample of more than 163,000 ideas collected from the Xiaomi MIUI community, we analyse influencing factors that increase the likelihood of ideas being preselected or reviewed. Results show that user status, user initiative contribution, and community recognition have a significantly positive influence on idea preselction, whereas user response contribution has no influence. Idea presentation characteristics have an inverted U-curve relationship with idea adoption. Community absorptive capacity has a moderate effect on the curvilinear relationship between idea description length and idea adoption.},
language = {en}
}
@article{YangHuDingetal.2018,
author = {Yang, Guang and Hu, Rongting and Ding, Hong-ming and Kochovski, Zdravko and Mei, Shilin and Lu, Yan and Ma, Yu-qiang and Chen, Guosong and Jiang, Ming},
title = {CO2-switchable response of protein microtubules},
series = {Materials chemistry frontiers},
volume = {2},
journal = {Materials chemistry frontiers},
number = {9},
publisher = {Royal Society of Chemistry},
address = {Cambridge},
issn = {2052-1537},
doi = {10.1039/c8qm00245b},
pages = {1642 -- 1646},
year = {2018},
abstract = {Recently, we proposed a small molecular inducing ligand strategy to assemble proteins into highly-ordered structures via dual non-covalent interactions, i.e. carbohydrate-protein interaction and dimerization of Rhodamine B. Using this approach, artificial protein microtubules were successfully constructed. In this study, we find that these microtubules exhibit a perfect CO2 responsiveness; assembly and disassembly of these microtubules were nicely controlled by the alternative passage of CO2 and N-2. Upon the injection of CO2, a negative net-charged SBA turns into a neutral or positive net-charged SBA, which elongated, to some extent, the effective distance between SBA and Rhodamine B, resulting in the disassociation of the Rhodamine B dimer. Further experimental and simulation results reveal that the CO2-responsive mechanism differs from that of solubility change of the previously reported CO2-responsive synthetic materials.},
language = {en}
}
@article{HuChengXuetal.2021,
author = {Hu, Ting-Li and Cheng, Feng and Xu, Zhen and Chen, Zhong-Zheng and Yu, Lei and Ban, Qian and Li, Chun-Lin and Pan, Tao and Zhang, Bao-Wei},
title = {Molecular and morphological evidence for a new species of the genus Typhlomys (Rodentia: Platacanthomyidae)},
series = {Zoological research : ZR = Dongwuxue-yanjiu : jikan / published by Kunming Institute of Zoology, Chinese Academy of Sciences, Zhongguo Kexueyuan Kunming Dongwu Yanjiusuo zhuban, Dongwuxue-yanjiu Bianji Weiyuanhui bianji},
volume = {42},
journal = {Zoological research : ZR = Dongwuxue-yanjiu : jikan / published by Kunming Institute of Zoology, Chinese Academy of Sciences, Zhongguo Kexueyuan Kunming Dongwu Yanjiusuo zhuban, Dongwuxue-yanjiu Bianji Weiyuanhui bianji},
number = {1},
publisher = {Yunnan Renmin Chubanshe},
address = {Kunming},
issn = {2095-8137},
doi = {10.24272/j.issn.2095-8137.2020.132},
pages = {100 -- 107},
year = {2021},
abstract = {In this study, we reassessed the taxonomic position of Typhlomys (Rodentia: Platacanthomyidae) from Huangshan, Anhui, China, based on morphological and molecular evidence. Results suggested that Typhlomys is comprised of up to six species, including four currently recognized species ( Typhlomys cinereus, T. chapensis, T. daloushanensis, and T. nanus), one unconfirmed candidate species, and one new species ( Typhlomys huangshanensis sp. nov.). Morphological analyses further supported the designation of the Huangshan specimens found at mid-elevations in the southern Huangshan Mountains (600 m to 1 200 m a.s.l.) as a new species.},
language = {en}
}
@article{HerzschuhCaoLaeppleetal.2019,
author = {Herzschuh, Ulrike and Cao, Xianyong and Laepple, Thomas and Dallmeyer, Anne and Telford, Richard J. and Ni, Jian and Chen, Fahu and Kong, Zhaochen and Liu, Guangxiu and Liu, Kam-Biu and Liu, Xingqi and Stebich, Martina and Tang, Lingyu and Tian, Fang and Wang, Yongbo and Wischnewski, Juliane and Xu, Qinghai and Yan, Shun and Yang, Zhenjing and Yu, Ge and Zhang, Yun and Zhao, Yan and Zheng, Zhuo},
title = {Position and orientation of the westerly jet determined Holocene rainfall patterns in China},
series = {Nature Communications},
volume = {10},
journal = {Nature Communications},
publisher = {Nature Publ. Group},
address = {London},
issn = {2041-1723},
doi = {10.1038/s41467-019-09866-8},
pages = {8},
year = {2019},
abstract = {Proxy-based reconstructions and modeling of Holocene spatiotemporal precipitation patterns for China and Mongolia have hitherto yielded contradictory results indicating that the basic mechanisms behind the East Asian Summer Monsoon and its interaction with the westerly jet stream remain poorly understood. We present quantitative reconstructions of Holocene precipitation derived from 101 fossil pollen records and analyse them with the help of a minimal empirical model. We show that the westerly jet-stream axis shifted gradually southward and became less tilted since the middle Holocene. This was tracked by the summer monsoon rain band resulting in an early-Holocene precipitation maximum over most of western China, a mid-Holocene maximum in north-central and northeastern China, and a late-Holocene maximum in southeastern China. Our results suggest that a correct simulation of the orientation and position of the westerly jet stream is crucial to the reliable prediction of precipitation patterns in China and Mongolia.},
language = {en}
}
@article{AbdallaAdamAharonianetal.2020,
author = {Abdalla, H. and Adam, R. and Aharonian, Felix A. and Benkhali, F. Ait and Ang{\"u}ner, Ekrem Oǧuzhan and Arcaro, C. and Armand, C. and Armstrong, T. and Ashkar, H. and Backes, M. and Baghmanyan, V. and Martins, V. Barbosa and Barnacka, A. and Barnard, M. and Becherini, Y. and Berge, D. and Bernlohr, K. and Bi, B. and Bottcher, M. and Boisson, C. and Bolmont, J. and de Lavergne, M. de Bony and Bordas, Pol and Breuhaus, M. and Brun, F. and Brun, P. and Bryan, M. and Buchele, M. and Bulik, T. and Bylund, T. and Caroff, S. and Carosi, A. and Casanova, Sabrina and Chand, T. and Chandra, S. and Chen, A. and Cotter, G. and Curylo, M. and Mbarubucyeye, J. Damascene and Davids, I. D. and Davies, J. and Deil, C. and Devin, J. and deWilt, P. and Dirson, L. and Djannati-Atai, A. and Dmytriiev, A. and Donath, A. and Doroshenko, V. and Duffy, C. and Dyks, J. and Egberts, Kathrin and Eichhorn, F. and Einecke, S. and Emery, G. and Ernenwein, J. -P. and Feijen, K. and Fegan, S. and Fiasson, A. and de Clairfontaine, G. Fichet and Fontaine, G. and Funk, S. and Fussling, Matthias and Gabici, S. and Gallant, Y. A. and Giavitto, G. and Giunti, L. and Glawion, D. and Glicenstein, J. F. and Gottschall, D. and Grondin, M. -H. and Hahn, J. and Haupt, M. and Hermann, G. and Hinton, J. A. and Hofmann, W. and Hoischen, Clemens and Holch, T. L. and Holler, M. and Horbe, M. and Horns, D. and Huber, D. and Jamrozy, M. and Jankowsky, D. and Jankowsky, F. and Jardin-Blicq, A. and Joshi, V. and Jung-Richardt, I. and Kasai, E. and Kastendieck, M. A. and Katarzynski, K. and Katz, U. and Khangulyan, D. and Khelifi, B. and Klepser, S. and Kluzniak, W. and Komin, Nu. and Konno, R. and Kosack, K. and Kostunin, D. and Kreter, M. and Lamanna, G. and Lemiere, A. and Lemoine-Goumard, M. and Lenain, J. -P. and Levy, C. and Lohse, T. and Lypova, I. and Mackey, J. and Majumdar, J. and Malyshev, D. and Malyshev, D. and Marandon, V. and Marchegiani, P. and Marcowith, Alexandre and Mares, A. and Marti-Devesa, G. and Marx, R. and Maurin, G. and Meintjes, P. J. and Meyer, M. and Mitchell, A. and Moderski, R. and Mohamed, M. and Mohrmann, L. and Montanari, A. and Moore, C. and Morris, P. and Moulin, Emmanuel and Muller, J. and Murach, T. and Nakashima, K. and Nayerhoda, A. and de Naurois, M. and Ndiyavala, H. and Niederwanger, F. and Niemiec, J. and Oakes, L. and O'Brien, Patrick and Odaka, H. and Ohm, S. and Olivera-Nieto, L. and Wilhelmi, E. de Ona and Ostrowski, M. and Oya, I. and Panter, M. and Panny, S. and Parsons, R. D. and Peron, G. and Peyaud, B. and Piel, Q. and Pita, S. and Poireau, V. and Noel, A. Priyana and Prokhorov, D. A. and Prokoph, H. and Puhlhofer, G. and Punch, M. and Quirrenbach, A. and Raab, S. and Rauth, R. and Reichherzer, P. and Reimer, A. and Reimer, O. and Remy, Q. and Renaud, M. and Rieger, F. and Rinchiuso, L. and Romoli, C. and Rowell, G. and Rudak, B. and Ruiz-Velasco, E. and Sahakian, V. and Sailer, S. and Sanchez, D. A. and Santangelo, Andrea and Sasaki, M. and Scalici, M. and Schussler, F. and Schutte, H. M. and Schwanke, U. and Schwemmer, S. and Seglar-Arroyo, M. and Senniappan, M. and Seyffert, A. S. and Shafi, N. and Shiningayamwe, K. and Simoni, R. and Sinha, A. and Sol, H. and Specovius, A. and Spencer, S. and Spir-Jacob, M. and Stawarz, L. and Sun, L. and Steenkamp, R. and Stegmann, C. and Steinmassl, S. and Steppa, C. and Takahashi, T. and Tavernier, T. and Taylor, A. M. and Terrier, R. and Tiziani, D. and Tluczykont, M. and Tomankova, L. and Trichard, C. and Tsirou, M. and Tuffs, R. and Uchiyama, Y. and van der Walt, D. J. and van Eldik, C. and van Rensburg, C. and van Soelen, B. and Vasileiadis, G. and Veh, J. and Venter, C. and Vincent, P. and Vink, J. and Volk, H. J. and Vuillaume, T. and Wadiasingh, Z. and Wagner, S. J. and Watson, J. and Werner, F. and White, R. and Wierzcholska, A. and Wong, Yu Wun and Yusafzai, A. and Zacharias, M. and Zanin, R. and Zargaryan, D. and Zdziarski, A. A. and Zech, Alraune and Zhu, S. J. and Ziegler, A. and Zorn, J. and Zouari, S. and Zywucka, N.},
title = {An extreme particle accelerator in the Galactic plane},
series = {Astronomy and astrophysics : an international weekly journal},
volume = {644},
journal = {Astronomy and astrophysics : an international weekly journal},
publisher = {EDP Sciences},
address = {Les Ulis},
organization = {HESS Collaboration},
issn = {0004-6361},
doi = {10.1051/0004-6361/202038851},
pages = {8},
year = {2020},
abstract = {The unidentified very-high-energy (VHE; E > 0.1 TeV) gamma -ray source, HESS J1826-130, was discovered with the High Energy Stereoscopic System (HESS) in the Galactic plane. The analysis of 215 h of HESS data has revealed a steady gamma -ray flux from HESS J1826-130, which appears extended with a half-width of 0.21 degrees +/- 0.02
(stat)degrees
stat degrees +/- 0.05
(sys)degrees sys degrees . The source spectrum is best fit with either a power-law function with a spectral index Gamma = 1.78 +/- 0.10(stat) +/- 0.20(sys) and an exponential cut-off at 15.2
(+5.5)(-3.2) -3.2+5.5 TeV, or a broken power-law with Gamma (1) = 1.96 +/- 0.06(stat) +/- 0.20(sys), Gamma (2) = 3.59 +/- 0.69(stat) +/- 0.20(sys) for energies below and above E-br = 11.2 +/- 2.7 TeV, respectively. The VHE flux from HESS J1826-130 is contaminated by the extended emission of the bright, nearby pulsar wind nebula, HESS J1825-137, particularly at the low end of the energy spectrum. Leptonic scenarios for the origin of HESS J1826-130 VHE emission related to PSR J1826-1256 are confronted by our spectral and morphological analysis. In a hadronic framework, taking into account the properties of dense gas regions surrounding HESS J1826-130, the source spectrum would imply an astrophysical object capable of accelerating the parent particle population up to greater than or similar to 200 TeV. Our results are also discussed in a multiwavelength context, accounting for both the presence of nearby supernova remnants, molecular clouds, and counterparts detected in radio, X-rays, and TeV energies.},
language = {en}
}