@article{DamesZimmermannSchmidtetal.2006,
  author    = {Dames, Petra and Zimmermann, Bernhard and Schmidt, Ruth and Rein, Julia and Voss, Martin and Schewe, Bettina and Walz, Bernd and Baumann, Otto},
  title     = {cAMP regulates plasma membrane vacuolar-type H+-ATPase assembly and activity in blowfly salivary glands},
  issn      = {0027-8424},
  doi       = {10.1073/pnas.0600011103},
  year      = {2006},
  abstract  = {Reversible assembly of the V0V1 holoenzyme from V-0 and V-1 subcomplexes is a widely used mechanism for regulation of vacuolar-type H+-ATPases (V-ATPases) in animal cells. in the blowfly (Calliphora vicina) salivary gland, V- ATPase is located in the apical membrane of the secretory cells and energizes the secretion of a KCl-rich saliva in response to the hormone serotonin. We have examined whether the CAMP pathway, known to be activated by serotonin, controls V-ATPase assembly and activity. Fluorescence measurements of pH changes at the luminal surface of isolated glands demonstrate that CAMP, Sp-adenosine-3',5'-cyclic monophosphorothioate, or forskolin, similar to serotonin, cause V-ATPase-dependent luminal acidification. In addition, V-ATPase-dependent ATP hydrolysis increases upon treatment with these agents. Immunofluorescence microscopy and pelleting assays have demonstrated further that V, components become translocated from the cytoplasm to the apical membrane and V-ATPase holoenzymes are assembled at the apical membrane during conditions that increase intracellular cAMP. Because these actions occur without a change in cytosolic Ca2+, our findings suggest that the cAMP pathway mediates the reversible assembly and activation of V-ATPase molecules at the apical membrane upon hormonal stimulus},
  language  = {en}
}
@article{ZimmermannDamesWalzetal.2003,
  author    = {Zimmermann, Bernhard and Dames, Petra and Walz, Bernd and Baumann, Otto},
  title     = {Distribution and serotonin-induced activation of vacuolar-type H+-ATPase in the salivary glands of the blowfly Calliphora vicina},
  year      = {2003},
  language  = {en}
}
@article{WalzZimmermannSeidl1994,
  author    = {Walz, Bernd and Zimmermann, Bernhard and Seidl, Siegfried},
  title     = {Intracellular Ca2+ concentration and latency of light-induced Ca2+ changes in photoreceptors of the honeybee drone},
  year      = {1994},
  language  = {en}
}
@article{Zimmermann1998,
  author    = {Zimmermann, Bernhard},
  title     = {Calcium store depletion activates two distinct calcium entry pathways in secretory cells of the blowfly salivary gland},
  year      = {1998},
  language  = {en}
}
@article{ReinZimmermannHilleetal.2006,
  author    = {Rein, Julia and Zimmermann, Bernhard and Hille, Carsten and Lang, Ingo and Walz, Bernd and Baumann, Otto},
  title     = {Fluorescence measurements of serotonin-induced V-ATPase-dependent pH changes at the luminal surface in salivary glands of the blowfly Calliphora vicina},
  issn      = {0022-0949},
  doi       = {10.1242/Jeb.02187},
  year      = {2006},
  abstract  = {Secretion in blowfly salivary glands is induced by the neurohormone serotonin and powered by a vacuolar-type H+- ATPase (V-ATPase) located in the apical membrane of the secretory cells. We have established a microfluorometric method for analysing pH changes at the luminal surface of the secretory epithelial cells by using the fluorescent dye 5-N- hexadecanoyl-aminofluorescein (HAF). After injection of HAF into the lumen of the tubular salivary gland, the fatty acyl chain of the dye molecule partitions into the outer leaflet of the plasma membrane and its pH-sensitive fluorescent moiety is exposed at the cell surface. Confocal imaging has confirmed that HAF distributes over the entire apical membrane of the secretory cells and remains restricted to this membrane domain. Ratiometric analysis of HAF fluorescence demonstrates that serotonin leads to a reversible dose-dependent acidification at the luminal surface. Inhibition by concanamycin A confirms that the serotonin-induced acidification at the luminal surface is due to H+ transport across the apical membrane via V-ATPase. Measurements with pH-sensitive microelectrodes corroborate a serotonin-induced luminal acidification and demonstrate that luminal pH decreases by about 0.4 pH units at saturating serotonin concentrations. We conclude that ratiometric measurements of HAF fluorescence provide an elegant method for monitoring V-ATPase-dependent H+ transport in the blowfly salivary gland in vivo and for analysing the spatiotemporal pattern of pH changes at the luminal surface},
  language  = {en}
}
@article{WalzBaumannZimmermannetal.1995,
  author    = {Walz, Bernd and Baumann, Otto and Zimmermann, Bernhard and Ciriacy-Wantrup, E.v.},
  title     = {Caffeine- and ryanodine-sensitive Ca2+-induced Ca2+ release from the endo plasmatic reticulum in honeybee photoreceptors},
  year      = {1995},
  language  = {en}
}
@article{ZimmermannWalz1997,
  author    = {Zimmermann, Bernhard and Walz, Bernd},
  title     = {Serotonin-induced intercellular calcium waves in salivary glands of the blowfley Calliphora erythrocephala},
  year      = {1997},
  language  = {en}
}
@article{WalzUkhanovZimmermann2000,
  author    = {Walz, Bernd and Ukhanov, Kyrill and Zimmermann, Bernhard},
  title     = {Actions of neomycin on electrical light responses : Ca2+ release and intracellular Ca2+ changes in photoreceptors of the honeybee drone},
  issn      = {0340-7594},
  year      = {2000},
  language  = {en}
}
@article{Zimmermann2000,
  author    = {Zimmermann, Bernhard},
  title     = {Control of insP(3)-induced Ca2+ oscillations in permeabilized blowfly salivary gland cells : contribution of mitochondria},
  issn      = {0022-3751},
  year      = {2000},
  language  = {en}
}
@article{Zimmermann2000,
  author    = {Zimmermann, Bernhard},
  title     = {Subcellular organization of agonist-evoked Ca2+ waves in the blowfly salivary gland},
  year      = {2000},
  language  = {en}
}
@article{ZimmermannWalz1999,
  author    = {Zimmermann, Bernhard and Walz, Bernd},
  title     = {The mechanism mediating regenerative intercellular Ca2+ waves in the blowfly salivary gland},
  year      = {1999},
  language  = {en}
}
@article{CourtinAndreevRaschkeetal.2021,
  author    = {Courtin, J{\´e}r{\´e}my and Andreev, Andrei and Raschke, Elena and Bala, Sarah and Biskaborn, Boris and Liu, Sisi and Zimmermann, Heike and Diekmann, Bernhard and Stoof-Leichsenring, Kathleen R. and Pestryakova, Luidmila Agafyevna and Herzschuh, Ulrike},
  title     = {Vegetation changes in Southeastern Siberia during the late pleistocene and the holocene},
  series = {Frontiers in Ecology and Evolution},
  volume    = {9},
  journal   = {Frontiers in Ecology and Evolution},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-701X},
  doi       = {10.3389/fevo.2021.625096},
  pages     = {18},
  year      = {2021},
  abstract  = {Relationships between climate, species composition, and species richness are of particular importance for understanding how boreal ecosystems will respond to ongoing climate change. This study aims to reconstruct changes in terrestrial vegetation composition and taxa richness during the glacial Late Pleistocene and the interglacial Holocene in the sparsely studied southeastern Yakutia (Siberia) by using pollen and sedimentary ancient DNA (sedaDNA) records. Pollen and sedaDNA metabarcoding data using the trnL g and h markers were obtained from a sediment core from Lake Bolshoe Toko. Both proxies were used to reconstruct the vegetation composition, while metabarcoding data were also used to investigate changes in plant taxa richness. The combination of pollen and sedaDNA approaches allows a robust estimation of regional and local past terrestrial vegetation composition around Bolshoe Toko during the last similar to 35,000 years. Both proxies suggest that during the Late Pleistocene, southeastern Siberia was covered by open steppe-tundra dominated by graminoids and forbs with patches of shrubs, confirming that steppe-tundra extended far south in Siberia. Both proxies show disturbance at the transition between the Late Pleistocene and the Holocene suggesting a period with scarce vegetation, changes in the hydrochemical conditions in the lake, and in sedimentation rates. Both proxies document drastic changes in vegetation composition in the early Holocene with an increased number of trees and shrubs and the appearance of new tree taxa in the lake's vicinity. The sedaDNA method suggests that the Late Pleistocene steppe-tundra vegetation supported a higher number of terrestrial plant taxa than the forested Holocene. This could be explained, for example, by the "keystone herbivore" hypothesis, which suggests that Late Pleistocene megaherbivores were able to maintain a high plant diversity. This is discussed in the light of the data with the broadly accepted species-area hypothesis as steppe-tundra covered such an extensive area during the Late Pleistocene.},
  language  = {en}
}