@article{FeinerTeschnerTeschneretal.2019,
  author    = {Feiner, Rebecca Christine and Teschner, Julian and Teschner, Kathrin E. and Radukic, Marco T. and Baumann, Tobias and Hagen, Sven and Hannappel, Yvonne and Biere, Niklas and Anselmetti, Dario and Arndt, Katja Maren and M{\"u}ller, Kristian Mark},
  title     = {rAAV Engineering for Capsid-Protein Enzyme Insertions and Mosaicism Reveals Resilience to Mutational, Structural and Thermal Perturbations},
  series = {International journal of molecular sciences},
  volume    = {20},
  journal   = {International journal of molecular sciences},
  number    = {22},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1422-0067},
  doi       = {10.3390/ijms20225702},
  pages     = {19},
  year      = {2019},
  abstract  = {Recombinant adeno-associated viruses (rAAV) provide outstanding options for customization and superior capabilities for gene therapy. To access their full potential, facile genetic manipulation is pivotal, including capsid loop modifications. Therefore, we assessed capsid tolerance to modifications of the structural VP proteins in terms of stability and plasticity. Flexible glycine-serine linkers of increasing sizes were, at the genetic level, introduced into the 587 loop region of the VP proteins of serotype 2, the best studied AAV representative. Analyses of biological function and thermal stability with respect to genome release of viral particles revealed structural plasticity. In addition, insertion of the 29 kDa enzyme beta-lactamase into the loop region was tested with a complete or a mosaic modification setting. For the mosaic approach, investigation of VP2 trans expression revealed that a Kozak sequence was required to prevent leaky scanning. Surprisingly, even the full capsid modification with beta-lactamase allowed for the assembly of capsids with a concomitant increase in size. Enzyme activity assays revealed lactamase functionality for both rAAV variants, which demonstrates the structural robustness of this platform technology.},
  language  = {en}
}
@article{BaumannKritikos2016,
  author    = {Baumann, Julian and Kritikos, Alexander},
  title     = {The link between R\&D, innovation and productivity: Are micro firms different?},
  series = {Research Policy},
  volume    = {45},
  journal   = {Research Policy},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0048-7333},
  doi       = {10.1016/j.respol.2016.03.008},
  pages     = {1263 -- 1274},
  year      = {2016},
  abstract  = {We analyze the link between R\&D, innovation, and productivity in MSMEs with a special focus on micro firms with fewer than 10 employees; usually constituting the majority of firms in industrialized economies. Using the German KfW SME-panel, we examine to what extent micro firms are different from other firms in terms of innovativeness. We find that while firms engage in innovative activities with smaller probability, the smaller they are, for those firms that do make such investment, R\&D intensity is larger the smaller firms are. For all MSMEs, the predicted R\&D intensity is positively correlated with the probability of reporting innovation, with a larger effect size for product than for process innovations. Moreover, micro firms benefit in a comparable way from innovation processes as larger firms, as they are similarly able to increase their labor productivity. Overall, the link between R\&D, innovation, and productivity in micro firms does not largely differ from their larger counterparts. (C) 2016 Elsevier B.V. All rights reserved.},
  language  = {en}
}
@phdthesis{Baumann2016,
  author    = {Baumann, Julian},
  title     = {Four essays in innovation and industrial economics},
  pages     = {i-xii, 123, xiv-xxvii},
  year      = {2016},
  language  = {en}
}
@misc{AustHeinemannHenniesetal.2014,
  author    = {Aust, Gottfried and Heinemann, Steffi and Hennies, Johannes and Penke, Martina and Rothweiler, Monika and Wimmer, Eva and Hess, Markus and Becker, Maryanne and Ehrmann-Neuhoff, Brigitte and Hamann, Elke and Wachtlin, Bianka and Sch{\"a}fer, Blanca and W{\"u}rzner, Kay-Michael and Heister, Julian and Schroeder, Sascha and D{\"u}sterh{\"o}ft, Stefanie and Tr{\"u}ggelmann, Maria and Richter, Kerstin and Gagarina, Natalʹja Vladimirovna and Posse, Dorothea and Topaj, Nathalie and Acikg{\"o}z, Duygu and Neumann, Charleen and Baumann, Jeannine and Meyer, Sarah and Siegm{\"u}ller, Julia and K{\"o}sterke-Buchardt, Antje and Jung, Kristina and Jassens, Frank and Golchert, Kristin and Wolff von Gudenberg, Alexander and Schmidt, Sabine and Kisielewicz, Daria and Heide, Judith and G{\"o}ldner, Angie and Ostermann, Anja},
  title     = {Spektrum Patholinguistik = Schwerpunktthema: H{\"o}ren - Zuh{\"o}ren - Dazugeh{\"o}ren : Sprachtherapie bei H{\"o}rst{\"o}rungen und Cochlea-Implantat},
  number    = {7},
  editor    = {Adelt, Anne and Fritzsche, Tom and Roß, Jennifer and D{\"u}sterh{\"o}ft, Stefanie},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  organization    = {Verband f{\"u}r Patholinguistik e. V.},
  isbn      = {978-3-86956-294-0},
  issn      = {1869-3822},
  doi       = {10.25932/publishup-6848},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-70629},
  year      = {2014},
  abstract  = {Das Herbsttreffen Patholinguistik wird seit 2007 j{\"a}hrlich vom Verband f{\"u}r Patholinguistik e.V. (vpl) durchgef{\"u}hrt. Das 7. Herbsttreffen mit dem Schwerpunktthema "H{\"o}ren - Zuh{\"o}ren - Dazugeh{\"o}ren: Sprachtherapie bei H{\"o}rst{\"o}rungen und Cochlea-Implantat" fand am 16.11.2013 in Potsdam statt. Der vorliegende Tagungsband beinhaltet die sechs Vortr{\"a}ge zum Schwerpunktthema aus verschiedenen Perspektiven: der medizinischen, der therapeutischen, der wissenschaftlichen sowie der von Betroffenen. Weiterhin sind die Beitr{\"a}ge der Posterpr{\"a}sentationen zu Themen der sprachtherapeutischen Forschung und Praxis abgedruckt.},
  language  = {de}
}