@phdthesis{Buerger2016,
  author    = {B{\"u}rger, Arne},
  title     = {MaiStep - Mainzer Schultraining zur Essst{\"o}rungspr{\"a}vention},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-98369},
  school      = {Universit{\"a}t Potsdam},
  pages     = {IX, 160},
  year      = {2016},
  abstract  = {Objectives The aim of this doctoral thesis was to investigate the efficacy of a German skills-based primary prevention program for partial-syndrome and full-syndrome eating disorders (Mainzer Schultraining zur Essst{\"o}rungspr{\"a}vention (MaiStep)) in reducing eating disorder symptoms as the primary outcome and associated psychopathology as a secondary outcome. Design Randomized Controlled Trial (RCT), three-intervention-group design, with two intervention groups and one active control group with a 3-month and 12-month follow-up. Setting A project in nine schools within the state of Rhineland-Palatine, Germany; funded by the Ministry of Health and Social Affairs (MSAGD) and the Ministry of Education, Culture and Research (MBWWK). Participants 1,654 adolescents (female/male: 781/873; mean age: 13.1±0.7; BMI: 20.0±3.5) recruited from randomly selected schools. Interventions The implementation and development of the skills based program was based on a systematic review of 63 scientific articles regarding eating disorder prevention in childhood and adolescence. One intervention group was conducted by psychologists and one by trained teachers. The active control group was performed by trained teachers using a stress and addiction prevention program. Main outcome measures The primary outcome measure was the incidence of partial-syndrome and full-syndrome eating disorders after completion of the program; secondary outcomes included self-reported questionnaires about eating disorder pathology. Results MaiStep did not reveal significant group differences at 3-month follow-up but showed a significant difference between the intervention groups and the active control group for partial anorexia nervosa (CHI²(2)) = 8.74, p = .01**) and partial bulimia nervosa (CHI²(2) = 7.25, p = .02*) at 12-month follow-up. Consistent with the primary outcome, the secondary measures were even more effective in the intervention groups at 12-month follow-up. The subscales of the Eating Disorder Inventory (EDI-2) drive of thinness (F (2, 355) = 3.94, p = .02*) and perfectionism (F (2, 355) = 4.19, p = .01**) and the Body Image Avoidance Questionnaire (BIAQ) (F (2, 525) = 18.79, p = .01**) showed significant differences for the intervention groups and demonstrated the effectiveness of MaiStep. Conclusions MaiStep has shown to be a successful program to prevent eating disorders in adolescents at 13 to 15 years of age. In addition, MaiStep was equally effective when conducted by teachers compared to psychologists suggesting feasibility of implementation in real world settings. Trial registration MaiStep is registered at the German Clinical Trials Register (DRKS00005050).},
  language  = {de}
}
@article{FagesHanghojKhanetal.2019,
  author    = {Fages, Antoine and Hanghoj, Kristian and Khan, Naveed and Gaunitz, Charleen and Seguin-Orlando, Andaine and Leonardi, Michela and Constantz, Christian McCrory and Gamba, Cristina and Al-Rasheid, Khaled A. S. and Albizuri, Silvia and Alfarhan, Ahmed H. and Allentoft, Morten and Alquraishi, Saleh and Anthony, David and Baimukhanov, Nurbol and Barrett, James H. and Bayarsaikhan, Jamsranjav and Benecke, Norbert and Bernaldez-Sanchez, Eloisa and Berrocal-Rangel, Luis and Biglari, Fereidoun and Boessenkool, Sanne and Boldgiv, Bazartseren and Brem, Gottfried and Brown, Dorcas and Burger, Joachim and Crubezy, Eric and Daugnora, Linas and Davoudi, Hossein and Damgaard, Peter de Barros and de Chorro y de Villa-Ceballos, Maria de los Angeles and Deschler-Erb, Sabine and Detry, Cleia and Dill, Nadine and Oom, Maria do Mar and Dohr, Anna and Ellingvag, Sturla and Erdenebaatar, Diimaajav and Fathi, Homa and Felkel, Sabine and Fernandez-Rodriguez, Carlos and Garcia-Vinas, Esteban and Germonpre, Mietje and Granado, Jose D. and Hallsson, Jon H. and Hemmer, Helmut and Hofreiter, Michael and Kasparov, Aleksei and Khasanov, Mutalib and Khazaeli, Roya and Kosintsev, Pavel and Kristiansen, Kristian and Kubatbek, Tabaldiev and Kuderna, Lukas and Kuznetsov, Pavel and Laleh, Haeedeh and Leonard, Jennifer A. and Lhuillier, Johanna and von Lettow-Vorbeck, Corina Liesau and Logvin, Andrey and Lougas, Lembi and Ludwig, Arne and Luis, Cristina and Arruda, Ana Margarida and Marques-Bonet, Tomas and Silva, Raquel Matoso and Merz, Victor and Mijiddorj, Enkhbayar and Miller, Bryan K. and Monchalov, Oleg and Mohaseb, Fatemeh A. and Morales, Arturo and Nieto-Espinet, Ariadna and Nistelberger, Heidi and Onar, Vedat and Palsdottir, Albina H. and Pitulko, Vladimir and Pitskhelauri, Konstantin and Pruvost, Melanie and Sikanjic, Petra Rajic and Papesa, Anita Rapan and Roslyakova, Natalia and Sardari, Alireza and Sauer, Eberhard and Schafberg, Renate and Scheu, Amelie and Schibler, Jorg and Schlumbaum, Angela and Serrand, Nathalie and Serres-Armero, Aitor and Shapiro, Beth and Seno, Shiva Sheikhi and Shevnina, Irina and Shidrang, Sonia and Southon, John and Star, Bastiaan and Sykes, Naomi and Taheri, Kamal and Taylor, William and Teegen, Wolf-Rudiger and Vukicevic, Tajana Trbojevic and Trixl, Simon and Tumen, Dashzeveg and Undrakhbold, Sainbileg and Usmanova, Emma and Vahdati, Ali and Valenzuela-Lamas, Silvia and Viegas, Catarina and Wallner, Barbara and Weinstock, Jaco and Zaibert, Victor and Clavel, Benoit and Lepetz, Sebastien and Mashkour, Marjan and Helgason, Agnar and Stefansson, Kari and Barrey, Eric and Willerslev, Eske and Outram, Alan K. and Librado, Pablo and Orlando, Ludovic},
  title     = {Tracking five millennia of horse management with extensive ancient genome time series},
  series = {Cell},
  volume    = {177},
  journal   = {Cell},
  number    = {6},
  publisher = {Cell Press},
  address   = {Cambridge},
  issn      = {0092-8674},
  doi       = {10.1016/j.cell.2019.03.049},
  pages     = {1419 -- 1435},
  year      = {2019},
  abstract  = {Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (>= 1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modem legacy of past equestrian civilisations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modem breeding impacted genetic diversity more dramatically than the previous millennia of human management.},
  language  = {en}
}
@article{KuhlmannBuergerEsseretal.2015,
  author    = {Kuhlmann, Sophie Merle and B{\"u}rger, Arne and Esser, G{\"u}nter and Hammerle, Florian},
  title     = {A mindfulness-based stress prevention training for medical students (MediMind): study protocol for a randomized controlled trial},
  series = {Trials},
  volume    = {16},
  journal   = {Trials},
  publisher = {BioMed Central},
  address   = {London},
  issn      = {1745-6215},
  doi       = {10.1186/s13063-014-0533-9},
  pages     = {11},
  year      = {2015},
  abstract  = {Background: Medical training is very demanding and associated with a high prevalence of psychological distress. Compared to the general population, medical students are at a greater risk of developing a psychological disorder. Various attempts of stress management training in medical school have achieved positive results on minimizing psychological distress; however, there are often limitations. Therefore, the use of a rigorous scientific method is needed. The present study protocol describes a randomized controlled trial to examine the effectiveness of a specifically developed mindfulness-based stress prevention training for medical students that includes selected elements of cognitive behavioral strategies (MediMind). Methods/Design: This study protocol presents a prospective randomized controlled trial, involving four assessment time points: baseline, post-intervention, one-year follow-up and five-year follow-up. The aims include evaluating the effect on stress, coping, psychological morbidity and personality traits with validated measures. Participants are allocated randomly to one of three conditions: MediMind, Autogenic Training or control group. Eligible participants are medical or dental students in the second or eighth semester of a German university. They form a population of approximately 420 students in each academic term. A final total sample size of 126 (at five-year follow-up) is targeted. The trainings (MediMind and Autogenic Training) comprise five weekly sessions lasting 90 minutes each. MediMind will be offered to participants of the control group once the five-year follow-up is completed. The allotment is randomized with a stratified allocation ratio by course of studies, semester, and gender. After descriptive statistics have been evaluated, inferential statistical analysis will be carried out with a repeated measures ANOVA-design with interactions between time and group. Effect sizes will be calculated using partial.-square values. Discussion: Potential limitations of this study are voluntary participation and the risk of attrition, especially concerning participants that are allocated to the control group. Strengths are the study design, namely random allocation, follow-up assessment, the use of control groups and inclusion of participants at different stages of medical training with the possibility of differential analysis.},
  language  = {en}
}
@misc{KuhlmannBuergerEsseretal.2015,
  author    = {Kuhlmann, Sophie Merle and B{\"u}rger, Arne and Esser, G{\"u}nter and Hammerle, Florian},
  title     = {A mindfulness-based stress prevention training for medical students (MediMind)},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe 820},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe 820},
  number    = {820},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-42756},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-427568},
  pages     = {13},
  year      = {2015},
  abstract  = {Background: Medical training is very demanding and associated with a high prevalence of psychological distress. Compared to the general population, medical students are at a greater risk of developing a psychological disorder. Various attempts of stress management training in medical school have achieved positive results on minimizing psychological distress; however, there are often limitations. Therefore, the use of a rigorous scientific method is needed. The present study protocol describes a randomized controlled trial to examine the effectiveness of a specifically developed mindfulness-based stress prevention training for medical students that includes selected elements of cognitive behavioral strategies (MediMind). Methods/Design: This study protocol presents a prospective randomized controlled trial, involving four assessment time points: baseline, post-intervention, one-year follow-up and five-year follow-up. The aims include evaluating the effect on stress, coping, psychological morbidity and personality traits with validated measures. Participants are allocated randomly to one of three conditions: MediMind, Autogenic Training or control group. Eligible participants are medical or dental students in the second or eighth semester of a German university. They form a population of approximately 420 students in each academic term. A final total sample size of 126 (at five-year follow-up) is targeted. The trainings (MediMind and Autogenic Training) comprise five weekly sessions lasting 90 minutes each. MediMind will be offered to participants of the control group once the five-year follow-up is completed. The allotment is randomized with a stratified allocation ratio by course of studies, semester, and gender. After descriptive statistics have been evaluated, inferential statistical analysis will be carried out with a repeated measures ANOVA-design with interactions between time and group. Effect sizes will be calculated using partial η-square values. Discussion: Potential limitations of this study are voluntary participation and the risk of attrition, especially concerning participants that are allocated to the control group. Strengths are the study design, namely random allocation, follow-up assessment, the use of control groups and inclusion of participants at different stages of medical training with the possibility of differential analysis.},
  language  = {en}
}