@article{DraudeGallaPelsteretal.2013,
  author    = {Draude, F. and Galla, S. and Pelster, Axel and Tentschert, J. and Jungnickel, H. and Haase, Alfred and Mantion, Alexandre and Thuenemann, Andreas F. and Taubert, Andreas and Luch, A. and Arlinghaus, H. F.},
  title     = {ToF-SIMS and Laser-SNMS analysis of macrophages after exposure to silver nanoparticles},
  series = {Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films},
  volume    = {45},
  journal   = {Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films},
  number    = {1},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken},
  issn      = {0142-2421},
  doi       = {10.1002/sia.4902},
  pages     = {286 -- 289},
  year      = {2013},
  abstract  = {Silver nanoparticles (SNPs) are among the most commercialized nanoparticles because of their antibacterial effects. Besides being employed, e. g. as a coatingmaterial for sterile surfaces in household articles and appliances, the particles are also used in a broad range of medical applications. Their antibacterial properties make SNPs especially useful for wound disinfection or as a coating material for prostheses and surgical instruments. Because of their optical characteristics, the particles are of increasing interest in biodetection as well. Despite the widespread use of SNPs, there is little knowledge of their toxicity. Time-of-flight secondary ion mass spectrometry (ToF-SIMS) and laser post-ionization secondary neutral mass spectrometry (Laser-SNMS) were used to investigate the effects of SNPs on human macrophages derived from THP-1 cells in vitro. For this purpose, macrophages were exposed to SNPs. The SNP concentration ranges were chosen with regard to functional impairments of the macrophages. To optimize the analysis of the macrophages, a special silicon wafer sandwich preparation technique was employed; ToF-SIMS was employed to characterize fragments originating from macrophage cell membranes. With the use of this optimized sample preparation method, the SNP-exposed macrophages were analyzed with ToF-SIMS and with Laser-SNMS. With Laser-SNMS, the three-dimensional distribution of SNPs in cells could be readily detected with very high efficiency, sensitivity, and submicron lateral resolution. We found an accumulation of SNPs directly beneath the cell membrane in a nanoparticular state as well as agglomerations of SNPs inside the cells.},
  language  = {en}
}
@article{JungingerKuebelSchacheretal.2013,
  author    = {Junginger, Mathias and K{\"u}bel, Christian and Schacher, Felix H. and M{\"u}ller, Axel H. E. and Taubert, Andreas},
  title     = {Crystal structure and chemical composition of biomimetric calcium phosphate nanofibers},
  doi       = {10.1039/c3ra23348k},
  year      = {2013},
  abstract  = {Calcium phosphate nanofibers with a diameter of only a few nanometers and a cotton-ball-like aggregate morphology have been reported several times in the literature. Although fiber formation seems reproducible in a variety of conditions, the crystal structure and chemical composition of the fibers have been elusive. Using scanning transmission electron microscopy, low dose electron (nano)diffraction, energy-dispersive X-ray spectroscopy, and energy- filtered transmission electron microscopy, we have assigned crystal structures and chemical compositions to the fibers. Moreover, we demonstrate that the mineralization process yields true polymer/calcium phosphate hybrid materials where the block copolymer template is closely associated with the calcium phosphate.},
  language  = {en}
}
@misc{BleekTaubert2013,
  author    = {Bleek, Katrin and Taubert, Andreas},
  title     = {New developments in polymer-controlled, bioinspired calcium phosphate mineralization from aqueous solution},
  series = {Acta biomaterialia},
  volume    = {9},
  journal   = {Acta biomaterialia},
  number    = {5},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {1742-7061},
  doi       = {10.1016/j.actbio.2012.12.027},
  pages     = {6283 -- 6321},
  year      = {2013},
  abstract  = {The polymer-controlled and bioinspired precipitation of inorganic minerals from aqueous solution at near-ambient or physiological conditions avoiding high temperatures or organic solvents is a key research area in materials science. Polymer-controlled mineralization has been studied as a model for biomineralization and for the synthesis of (bioinspired and biocompatible) hybrid materials for a virtually unlimited number of applications. Calcium phosphate mineralization is of particular interest for bone and dental repair. Numerous studies have therefore addressed the mineralization of calcium phosphate using a wide variety of low- and high-molecular-weight additives. In spite of the growing interest and increasing number of experimental and theoretical data, the mechanisms of polymer-controlled calcium phosphate mineralization are not entirely clear to date, although the field has made significant progress in the last years. A set of elegant experiments and calculations has shed light on some details of mineral formation, but it is currently not possible to preprogram a mineralization reaction to yield a desired product for a specific application. The current article therefore summarizes and discusses the influence of (macro)molecular entities such as polymers, peptides, proteins and gels on biomimetic calcium phosphate mineralization from aqueous solution. It focuses on strategies to tune the kinetics, morphologies, final dimensions and crystal phases of calcium phosphate, as well as on mechanistic considerations.},
  language  = {en}
}
@article{BagdahnTaubert2013,
  author    = {Bagdahn, Christian and Taubert, Andreas},
  title     = {Ionogel fiber mats - functional materials via electrospinning of PMMA and the ionic liquid bis(1-butyl-3-methyl-imidazolium) Tetrachloridocuprate(II), [Bmim](2)[CuCl4]},
  series = {Zeitschrift f{\"u}r Naturforschung : B, Chemical sciences},
  volume    = {68},
  journal   = {Zeitschrift f{\"u}r Naturforschung : B, Chemical sciences},
  number    = {10},
  publisher = {De Gruyter},
  address   = {T{\"u}bingen},
  issn      = {0932-0776},
  doi       = {10.5560/ZNB.2013-3195},
  pages     = {1163 -- 1171},
  year      = {2013},
  abstract  = {Ionogel fiber mats were made by electrospinning poly(methylmethacrylate) (PMMA) and the ionic liquid (IL) bis(1-butyl-3-methyl-imidazolium) tetrachloridocupraten, [Bmim](2)[CuCl4], from acetone. The morphology of the electrospun ionogels strongly depends on the spinning parameters. Dense and uniform fiber mats were only obtained at concentrations of 60 to 70 g of polymer and IL mass combined. Lower concentrations led to a low number of poorly defined fibers. High voltages of 20 to 25 kV led to well-defined and uniform fibers; voltages between 15 and 20 kV again led to less uniform and less dense fibers. At 10 kV and lower, no spinning could be induced. Finally, PMMA fibers electrospun without IL show a less well-defined morphology combining fibers and oblong droplets indicating that the IL has a beneficial effect on the electrospinning process. The resulting materials are prototypes for new functional materials, for example in sterile filtration.},
  language  = {en}
}
@misc{BleekTaubert2013,
  author    = {Bleek, Katrin and Taubert, Andreas},
  title     = {New developments in polymer-controlled, bio-inspired calcium phosphate mineralization from aqueous solution},
  series = {Acta biomaterialia},
  volume    = {9},
  journal   = {Acta biomaterialia},
  number    = {9},
  publisher = {Elsevier},
  address   = {Oxford},
  issn      = {1742-7061},
  doi       = {10.1016/j.actbio.2013.05.007},
  pages     = {8466 -- 8466},
  year      = {2013},
  language  = {en}
}
@article{TentschertDraudeJungnickeletal.2013,
  author    = {Tentschert, J. and Draude, F. and Jungnickel, H. and Haase, A. and Mantion, Alexandre and Galla, S. and Thuenemann, Andreas F. and Taubert, Andreas and Luch, A. and Arlinghaus, H. F.},
  title     = {TOF-SIMS analysis of cell membrane changes in functional impaired human macrophages upon nanosilver treatment},
  series = {Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films},
  volume    = {45},
  journal   = {Surface and interface analysis : an international journal devoted to the development and application of techniques for the analysis surfaces, interfaces and thin films},
  number    = {1},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken},
  issn      = {0142-2421},
  doi       = {10.1002/sia.5155},
  pages     = {483 -- 485},
  year      = {2013},
  abstract  = {Silver nanoparticles (SNP) are among the most commercialized nanoparticles. Here, we show that peptide-coated SNP cause functional impairment of human macrophages. A dose-dependent inhibition of phagocytosis is observed after nanoparticle treatment, and pretreatment of cells with N-acetyl cysteine (NAC) can counteract the phagocytosis disturbances caused by SNP. Using the surface-sensitive mode of time-of-flight secondary ion mass spectrometry, in combination with multivariate statistical methods, we studied the composition of cell membranes in human macrophages upon exposure to SNP with and without NAC preconditioning. This method revealed characteristic changes in the lipid pattern of the cellular membrane outer leaflet in those cells challenged by SNP. Statistical analyses resulted in 19 characteristic ions, which can be used to distinguish between NAC pretreated and untreated macrophages. The present study discusses the assignments of surface cell membrane phospholipids for the identified ions and the resulting changes in the phospholipid pattern of treated cells. We conclude that the adverse effects in human macrophages caused by SNP can be partially reversed through NAC administration. Some alterations, however, remained.},
  language  = {en}
}
@article{UnuabonahOluOwolabiTaubertetal.2013,
  author    = {Unuabonah, Emmanuel I. and Olu-Owolabi, Bamidele I. and Taubert, Andreas and Omolehin, Elizabeth B. and Adebowale, Kayode O.},
  title     = {SAPK a novel composite resin for water treatment with very high Zn2+, Cd2+, and Pb2+ adsorption capacity},
  series = {Industrial \& engineering chemistry research},
  volume    = {52},
  journal   = {Industrial \& engineering chemistry research},
  number    = {2},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {0888-5885},
  doi       = {10.1021/ie3024577},
  pages     = {578 -- 585},
  year      = {2013},
  abstract  = {A new sulfonated aniline-modified poly(vinyl alcohol)/K-feldspar (SAPK) composite was prepared. The cation-exchange capacity of the composite was found to be S times that of neat feldspar. The specific surface area and point of zero charge also changed significantly upon modification, from 15.6 +/- 0.1 m(2)/g and 2.20 (K-feldspar) to 73.6 +/- 0.3 m(2)/g and 1.91 (SAPK). Zn2+, Cd2+, and Pb2+ adsorption was found to be largely independent of pH, and the metal adsorption rate on SAPK was higher than that on neat feldspar. This particularly applies to the initial adsorption rates. The adsorption process involves both film and pore diffusion; film diffusion initially controls the adsorption. The Freundlich and Langmuir models were found to fit metal-ion adsorption on SAPK most accurately. Adsorption on neat feldspar was best fitted with a Langmuir model, indicating the formation of adsorbate monolayers. Both pure feldspar and SAPK showed better selectivity for Pb2+ than for Cd2+ or Zn2+.},
  language  = {en}
}
@article{JungingerKuebelSchacheretal.2013,
  author    = {Junginger, Mathias and K{\"u}bel, Christian and Schacher, Felix H. and M{\"u}ller, Axel H. E. and Taubert, Andreas},
  title     = {Crystal structure and chemical composition of biomimetic calcium phosphate nanofibers},
  series = {RSC Advances},
  volume    = {3},
  journal   = {RSC Advances},
  number    = {28},
  publisher = {Royal Society of Chemistry},
  address   = {Cambridge},
  issn      = {2046-2069},
  doi       = {10.1039/c3ra23348k},
  pages     = {11301 -- 11308},
  year      = {2013},
  abstract  = {Calcium phosphate nanofibers with a diameter of only a few nanometers and a cotton-ball-like aggregate morphology have been reported several times in the literature. Although fiber formation seems reproducible in a variety of conditions, the crystal structure and chemical composition of the fibers have been elusive. Using scanning transmission electron microscopy, low dose electron (nano) diffraction, energy-dispersive X-ray spectroscopy, and energy-filtered transmission electron microscopy, we have assigned crystal structures and chemical compositions to the fibers. Moreover, we demonstrate that the mineralization process yields true polymer/calcium phosphate hybrid materials where the block copolymer template is closely associated with the calcium phosphate.},
  language  = {en}
}
@article{UnuabonahGuenterWeberetal.2013,
  author    = {Unuabonah, Emmanuel I. and G{\"u}nter, Christina and Weber, Jens and Lubahn, Susanne and Taubert, Andreas},
  title     = {Hybrid Clay - a new highly efficient adsorbent for water treatment},
  series = {ACS sustainable chemistry \& engineering},
  volume    = {1},
  journal   = {ACS sustainable chemistry \& engineering},
  number    = {8},
  publisher = {American Chemical Society},
  address   = {Washington},
  issn      = {2168-0485},
  doi       = {10.1021/sc400051y},
  pages     = {966 -- 973},
  year      = {2013},
  abstract  = {New hybrid clay adsorbent based on kaolinite clay and Carica papaya seeds with improved cation exchange capacity (CEC), rate of heavy metal ion uptake, and adsorption capacity for heavy metal ions were prepared. The CEC of the new material is ca. 75 meq/100 g in spite of the unexpectedly low surface area (approximate to 19 m(2)/g). Accordingly, the average particle size of the hybrid clay adsorbent decreased from over 200 to 100 pm. The hybrid clay adsorbent is a highly efficient adsorbent for heavy metals. With an initial metal concentration of 1 mg/L, the hybrid clay adsorbent reduces the Cd2+, Ni2+, and Pb2+ concentration in aqueous solution to <= 4, <= 7 and <= 20 mu g/L, respectively, from the first minute to over 300 min using a fixed bed containing 2 g of adsorbent and a flow rate of approximate to 7 mL/min. These values are (with the exception of Pb2+) in line with the WHO permissible limits for heavy metal ions. In a cocktail solution of Cd2+, and Ni2+, the hybrid clay shows a reduced rate of uptake but an increased adsorption capacity. The CEC data suggest that the adsorption of Pb2+, Cd2+, and Ni2+ on the hybrid clay adsorbent is essentially due to ion exchange. This hybrid clay adsorbent is prepared from materials that are abundant and by a simple means that is sustainable, easily recovered from aqueous solution, nonbiodegradable (unlike numerous biosorbent), and easily regenerated and is a highly efficient alternative to activated carbon for water treatment.},
  language  = {en}
}