@article{KutzschbachWunderKrstulovicetal.2016, author = {Kutzschbach, Martin and Wunder, Bernd and Krstulovic, Marija and Ertl, Andreas and Trumbull, Robert B. and Rocholl, Alexander and Giester, Gerald}, title = {First high-pressure synthesis of rossmanitic tourmaline and evidence for the incorporation of Li at the X site}, series = {Physics and chemistry of minerals / in cooperation with the International Mineralogical Association (IMA)}, volume = {44}, journal = {Physics and chemistry of minerals / in cooperation with the International Mineralogical Association (IMA)}, publisher = {Springer}, address = {New York}, issn = {0342-1791}, doi = {10.1007/s00269-016-0863-0}, pages = {353 -- 363}, year = {2016}, abstract = {Lithium is an important component of some tourmalines, especially in chemically evolved granites and pegmatites. All attempts at synthesizing Li-rich tourmaline have so far been unsuccessful. Here we describe the first synthesis of rossmanitic tourmaline at 4 GPa and 700 degrees C in the system Li2OAl2O3SiO2B2O3H2O (LASBH) from seed-free solid starting materials consisting of a homogenous mixture of Li2O, gamma-Al2O3, quartz and H3BO3. The solid run products after 12-day run duration comprise rossmanitic tourmaline (68 wt\%), dumortierite (28 wt\%) and traces of spodumene (3 wt\%) and coesite (1 wt\%). Tourmaline forms idiomorphic, large prismatic crystals (30 X 100 mu m), which are inclusion free and chemically unzoned. The refined cell dimensions of the tourmaline are: a = 15.7396(9) angstrom, c = 7.0575(5) angstrom, V = 1514.1(2) angstrom 3. Conventionally, the Li+ ion is assumed to exclusively occupy the octahedral Y site in the tourmaline structure to a maximum of 2 Li per formula unit (pfu). However, the chemical composition of our synthetic tourmaline determined by electron microprobe and secondary ion mass spectroscopy results in the formula: (X)(square Li-0.67(11)(0.33(11)))(Y)(Al2.53(10)Li0.47(10))(Z)(Al-6)T(Si5.42(15)B0.58(15))O-18(B)(BO3)(3)(V+W)[(OH)(2.40(3))O-1.60(3)], wherein a significant amount of Li occupies the X site for charge balance requirements. Reliable assignment of the OH-stretching vibrations in a polarized single-crystal Raman spectrum such as a single-crystal XRD structure refinement, confirms the incorporation of Li at the X site [0.24(9) and 0.15(5) Li-X pfu, respectively]. The SREF data show that the LiO1 distances are shortened significantly in order to compensate for the smaller ionic radius of Li+ compared to Na+, K+ or Ca2+ at the X site, i.e., Li is closer to the Si6O18 ring and to a sevenfold coordination with oxygen.}, language = {en} } @article{FelserDrummer2016, author = {Felser, Claudia and Drummer, Janna-Deborah}, title = {Sensitivity to Crossover Constraints During Native and Non-native Pronoun Resolution}, series = {Journal of psycholinguistic research}, volume = {46}, journal = {Journal of psycholinguistic research}, publisher = {Springer}, address = {New York}, issn = {0090-6905}, doi = {10.1007/s10936-016-9465-8}, pages = {771 -- 789}, year = {2016}, abstract = {We report the results from two experiments examining native and non-native German speakers' sensitivity to crossover constraints on pronoun resolution. Our critical stimuli sentences contained personal pronouns in either strong (SCO) or weak crossover (WCO) configurations. Using eye-movement monitoring during reading and a gender-mismatch paradigm, Experiment 1 investigated whether a fronted wh-phrase would be considered as a potential antecedent for a pronoun intervening between the wh-phrase and its canonical position. Both native and non-native readers initially attempted coreference in WCO but not in SCO configurations, as evidenced by early gender-mismatch effects in our WCO conditions. Experiment 2 was an offline antecedent judgement task whose results mirrored the SCO/WCO asymmetry observed in our reading-time data. Taken together, our results show that the SCO constraint immediately restricts pronoun interpretation in both native and non-native comprehension, and further suggest that SCO and WCO constraints derive from different sources.}, language = {en} } @article{DoerrNeumannSutton2016, author = {Doerr, Benjamin and Neumann, Frank and Sutton, Andrew M.}, title = {Time Complexity Analysis of Evolutionary Algorithms on Random Satisfiable k-CNF Formulas}, series = {Algorithmica : an international journal in computer science}, volume = {78}, journal = {Algorithmica : an international journal in computer science}, publisher = {Springer}, address = {New York}, issn = {0178-4617}, doi = {10.1007/s00453-016-0190-3}, pages = {561 -- 586}, year = {2016}, abstract = {We contribute to the theoretical understanding of randomized search heuristics by investigating their optimization behavior on satisfiable random k-satisfiability instances both in the planted solution model and the uniform model conditional on satisfiability. Denoting the number of variables by n, our main technical result is that the simple () evolutionary algorithm with high probability finds a satisfying assignment in time when the clause-variable density is at least logarithmic. For low density instances, evolutionary algorithms seem to be less effective, and all we can show is a subexponential upper bound on the runtime for densities below . We complement these mathematical results with numerical experiments on a broader density spectrum. They indicate that, indeed, the () EA is less efficient on lower densities. Our experiments also suggest that the implicit constants hidden in our main runtime guarantee are low. Our main result extends and considerably improves the result obtained by Sutton and Neumann (Lect Notes Comput Sci 8672:942-951, 2014) in terms of runtime, minimum density, and clause length. These improvements are made possible by establishing a close fitness-distance correlation in certain parts of the search space. This approach might be of independent interest and could be useful for other average-case analyses of randomized search heuristics. While the notion of a fitness-distance correlation has been around for a long time, to the best of our knowledge, this is the first time that fitness-distance correlation is explicitly used to rigorously prove a performance statement for an evolutionary algorithm.}, language = {en} } @article{RichtbergJakobHoeflingetal.2016, author = {Richtberg, Samantha and Jakob, Marion and Hoefling, Volkmar and Weck, Florian}, title = {Patient Characteristics and Patient Behavior as Predictors of Outcome in Cognitive Therapy and Exposure Therapy for Hypochondriasis}, series = {Journal of clinical psychology}, volume = {73}, journal = {Journal of clinical psychology}, number = {6}, publisher = {Wiley}, address = {Hoboken}, issn = {0021-9762}, doi = {10.1002/jclp.22356}, pages = {612 -- 625}, year = {2016}, abstract = {ObjectivePsychotherapy for hypochondriasis has greatly improved over the last decades and cognitive-behavioral treatments are most promising. However, research on predictors of treatment outcome for hypochondriasis is rare. Possible predictors of treatment outcome in cognitive therapy (CT) and exposure therapy (ET) for hypochondriasis were investigated. MethodCharacteristics and behaviors of 75 patients were considered as possible predictors: sociodemographic variables (sex, age, and cohabitation); psychopathology (pretreatment hypochondriacal symptoms, comorbid mental disorders, and levels of depression, anxiety, and somatic symptoms); and patient in-session interpersonal behavior. ResultsSeverity of pretreatment hypochondriacal symptoms, comorbid mental disorders, and patient in-session interpersonal behavior were significant predictors in multiple hierarchical regression analyses. Interactions between the predictors and the treatment (CT or ET) were not found. ConclusionsIn-session interpersonal behavior is an important predictor of outcome. Furthermore, there are no specific contraindications to treating hypochondriasis with CT or ET.}, language = {en} } @article{Schlosser2016, author = {Schlosser, Rainer}, title = {Stochastic dynamic pricing and advertising in isoelastic oligopoly models}, series = {European Journal of Operational Research}, volume = {259}, journal = {European Journal of Operational Research}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0377-2217}, doi = {10.1016/j.ejor.2016.11.021}, pages = {1144 -- 1155}, year = {2016}, abstract = {In this paper, we analyze stochastic dynamic pricing and advertising differential games in special oligopoly markets with constant price and advertising elasticity. We consider the sale of perishable as well as durable goods and include adoption effects in the demand. Based on a unique stochastic feedback Nash equilibrium, we derive closed-form solution formulas of the value functions and the optimal feedback policies of all competing firms. Efficient simulation techniques are used to evaluate optimally controlled sales processes over time. This way, the evolution of optimal controls as well as the firms' profit distributions are analyzed. Moreover, we are able to compare feedback solutions of the stochastic model with its deterministic counterpart. We show that the market power of the competing firms is exactly the same as in the deterministic version of the model. Further, we discover two fundamental effects that determine the relation between both models. First, the volatility in demand results in a decline of expected profits compared to the deterministic model. Second, we find that saturation effects in demand have an opposite character. We show that the second effect can be strong enough to either exactly balance or even overcompensate the first one. As a result we are able to identify cases in which feedback solutions of the deterministic model provide useful approximations of solutions of the stochastic model.}, language = {en} } @article{EdlichGereckeGiulbudagianetal.2016, author = {Edlich, Alexander and Gerecke, Christian and Giulbudagian, Michael and Neumann, Falko and Hedtrich, Sarah and Schaefer-Korting, Monika and Ma, Nan and Calderon, Marcelo and Kleuser, Burkhard}, title = {Specific uptake mechanisms of well-tolerated thermoresponsive polyglycerol-based nanogels in antigen-presenting cells of the skin}, series = {European Journal of Pharmaceutics and Biopharmaceutics}, volume = {116}, journal = {European Journal of Pharmaceutics and Biopharmaceutics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0939-6411}, doi = {10.1016/j.ejpb.2016.12.016}, pages = {155 -- 163}, year = {2016}, abstract = {Engineered nanogels are of high value for a targeted and controlled transport of compounds due to the ability to change their chemical properties by external stimuli. As it has been indicated that nanogels possess a high ability to penetrate the stratum corneum, it cannot be excluded that nanogels interact with dermal dendritic cells, especially in diseased skin. In this study the potential crosstalk of the thermore-sponsive nanogels (tNGs) with the dendritic cells of the skin was investigated with the aim to determine the immunotoxicological properties of the nanogels. The investigated tNGs were made of dendritic polyglycerol (dPG) and poly(glycidyl methyl ether-co-ethyl glycidyl ether) (p(GME-co-EGE)), as polymer conferring thermoresponsive properties. Although the tNGs were taken up, they displayed neither cytotoxic and genotoxic effects nor any induction of reactive oxygen species in the tested cells. Interestingly, specific uptake mechanisms of the tNGs by the dendritic cells were depending on the nanogels cloud point temperature (Tcp), which determines the phase transition of the nanoparticle. The study points to caveolae-mediated endocytosis as being the major tNGs uptake mechanism at 37 degrees C, which is above the Tcp of the tNGs. Remarkably, an additional uptake mechanism, beside caveolae-mediated endocytosis, was observed at 29 degrees C, which is the Tcp of the tNGs. At this temperature, which is characterized by two different states of the tNGs, macropinocytosis was involved as well. In summary, our study highlights the impact of thermoresponsivity on the cellular uptake mechanisms which has to be taken into account if the tNGs are used as a drug delivery system.}, language = {en} } @article{KornhuberPetoukhovPetrietal.2016, author = {Kornhuber, Kai and Petoukhov, Vladimir and Petri, Stefan and Rahmstorf, Stefan and Coumou, Dim}, title = {Evidence for wave resonance as a key mechanism for generating high-amplitude quasi-stationary waves in boreal summer}, series = {Climate dynamics : observational, theoretical and computational research on the climate system}, volume = {49}, journal = {Climate dynamics : observational, theoretical and computational research on the climate system}, publisher = {Springer}, address = {New York}, issn = {0930-7575}, doi = {10.1007/s00382-016-3399-6}, pages = {1961 -- 1979}, year = {2016}, abstract = {Several recent northern hemisphere summer extremes have been linked to persistent high-amplitude wave patterns (e.g. heat waves in Europe 2003, Russia 2010 and in the US 2011, Floods in Pakistan 2010 and Europe 2013). Recently quasi-resonant amplification (QRA) was proposed as a mechanism that, when certain dynamical conditions are fulfilled, can lead to such high-amplitude wave events. Based on these resonance conditions a detection scheme to scan reanalysis data for QRA events in boreal summer months was implemented. With this objective detection scheme we analyzed the occurrence and duration of QRA events and the associated atmospheric flow patterns in 1979-2015 reanalysis data. We detect a total number of 178 events for wave 6, 7 and 8 and find that during roughly one-third of all high amplitude events QRA conditions were met for respective waves. Our analysis reveals a significant shift for quasi-stationary waves 6 and 7 towards high amplitudes during QRA events, lagging first QRA-detection by typically one week. The results provide further evidence for the validity of the QRA hypothesis and its important role in generating high amplitude waves in boreal summer.}, language = {en} } @article{JungKraheBusching2016, author = {Jung, Janis Moritz and Krah{\´e}, Barbara and Busching, Robert}, title = {Beyond the positive reinforcement of aggression}, series = {International Journal of Behavioral Development}, volume = {42}, journal = {International Journal of Behavioral Development}, number = {1}, publisher = {Sage Publ.}, address = {London}, issn = {0165-0254}, doi = {10.1177/0165025416671613}, pages = {73 -- 82}, year = {2016}, abstract = {Being surrounded by peers who are accepting of aggression is a significant predictor of the development and persistence of aggression in childhood and adolescence. Whereas past research has focused on social reinforcement mechanisms as the underlying processes, the present longitudinal study analysed the role of external control beliefs as an additional mediator explaining the link between peers' acceptance of aggression and the development of aggressive behaviour. Drawing on a large community sample of N = 1,466 male and female children and adolescents from Germany aged between 10 and 18 years, results of latent structural equation modeling were consistent with the hypotheses that peer acceptance of aggression would predict external control beliefs in the social domain, which in turn, should predict aggressive behaviour over time. Additional multigroup analyses showed that the predicted pathways were consistent across gender and age groups.}, language = {en} } @article{JungKraheBondueetal.2016, author = {Jung, Janis Moritz and Krah{\´e}, Barbara and Bond{\"u}, Rebecca and Esser, G{\"u}nter and Wyschkon, Anne}, title = {Dynamic progression of antisocial behavior in childhood and adolescence}, series = {Applied Developmental Science}, volume = {22}, journal = {Applied Developmental Science}, number = {1}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {1088-8691}, doi = {10.1080/10888691.2016.1219228}, pages = {74 -- 88}, year = {2016}, abstract = {This longitudinal study from Germany examined the dynamic progression of antisocial behavior in childhood and adolescence based on the social interactional model by Patterson, DeBaryshe, and Ramsey. It examined the link between antisocial behavior, social rejection, academic failure, and affiliation with deviant peers in a sample of 1,657 children and youths aged between 6 and 15 years who were studied at three measurement waves (T1 to T3) over a time period of about 5 years. Teachers rated the children on all variables, parents additionally provided ratings of antisocial behavior and social rejection. Latent structural equation modeling yielded the predicted positive paths from antisocial behavior at T1 to social rejection and academic failure at T2. As predicted, affiliation with deviant peers at T2 was positively associated with social rejection and academic failure at the same measurement point. Finally, affiliation with deviant peers at T2 significantly predicted antisocial behavior at T3.}, language = {en} } @article{ZakariasKeresztesMartonetal.2016, author = {Zakari{\´a}s, Lilla and Keresztes, Attila and Marton, Klara and Wartenburger, Isabell}, title = {Positive effects of a computerised working memory and executive function}, series = {Neuropsychological rehabilitation}, volume = {28}, journal = {Neuropsychological rehabilitation}, number = {3}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0960-2011}, doi = {10.1080/09602011.2016.1159579}, pages = {369 -- 386}, year = {2016}, abstract = {Aphasia, the language disorder following brain damage, is frequently accompanied by deficits of working memory (WM) and executive functions (EFs). Recent studies suggest that WM, together with certain EFs, can play a role in sentence comprehension in individuals with aphasia (IWA), and that WM can be enhanced with intensive practice. Our aim was to investigate whether a combined WM and EF training improves the understanding of spoken sentences in IWA. We used a pre-post-test case control design. Three individuals with chronic aphasia practised an adaptive training task (a modified n-back task) three to four times a week for a month. Their performance was assessed before and after the training on outcome measures related to WM and spoken sentence comprehension. One participant showed significant improvement on the training task, another showed a tendency for improvement, and both of them improved significantly in spoken sentence comprehension. The third participant did not improve on the training task, however, she showed improvement on one measure of spoken sentence comprehension. Compared to controls, two individuals improved at least in one condition of the WM outcome measures. Thus, our results suggest that a combined WM and EF training can be beneficial for IWA.}, language = {en} }