@article{SairamBrillSiegetal.2021,
  author    = {Sairam, Nivedita and Brill, Fabio Alexander and Sieg, Tobias and Farrag, Mostafa and Kellermann, Patric and Viet Dung Nguyen, and L{\"u}dtke, Stefan and Merz, Bruno and Schr{\"o}ter, Kai and Vorogushyn, Sergiy and Kreibich, Heidi},
  title     = {Process-based flood risk assessment for Germany},
  series = {Earth's future / American Geophysical Union},
  volume    = {9},
  journal   = {Earth's future / American Geophysical Union},
  number    = {10},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken, NJ},
  issn      = {2328-4277},
  doi       = {10.1029/2021EF002259},
  pages     = {12},
  year      = {2021},
  abstract  = {Large-scale flood risk assessments are crucial for decision making, especially with respect to new flood defense schemes, adaptation planning and estimating insurance premiums. We apply the process-based Regional Flood Model (RFM) to simulate a 5000-year flood event catalog for all major catchments in Germany and derive risk curves based on the losses per economic sector. The RFM uses a continuous process simulation including a multisite, multivariate weather generator, a hydrological model considering heterogeneous catchment processes, a coupled 1D-2D hydrodynamic model considering dike overtopping and hinterland storage, spatially explicit sector-wise exposure data and empirical multi-variable loss models calibrated for Germany. For all components, uncertainties in the data and models are estimated. We estimate the median Expected Annual Damage (EAD) and Value at Risk at 99.5\% confidence for Germany to be euro0.529 bn and euro8.865 bn, respectively. The commercial sector dominates by making about 60\% of the total risk, followed by the residential sector. The agriculture sector gets affected by small return period floods and only contributes to less than 3\% to the total risk. The overall EAD is comparable to other large-scale estimates. However, the estimation of losses for specific return periods is substantially improved. The spatial consistency of the risk estimates avoids the large overestimation of losses for rare events that is common in other large-scale assessments with homogeneous return periods. Thus, the process-based, spatially consistent flood risk assessment by RFM is an important step forward and will serve as a benchmark for future German-wide flood risk assessments.},
  language  = {en}
}
@article{VanHoutTachmazidouBackmanetal.2020,
  author    = {Van Hout, Cristopher V. and Tachmazidou, Ioanna and Backman, Joshua D. and Hoffman, Joshua D. and Liu, Daren and Pandey, Ashutosh K. and Gonzaga-Jauregui, Claudia and Khalid, Shareef and Ye, Bin and Banerjee, Nilanjana and Li, Alexander H. and O'Dushlaine, Colm and Marcketta, Anthony and Staples, Jeffrey and Schurmann, Claudia and Hawes, Alicia and Maxwell, Evan and Barnard, Leland and Lopez, Alexander and Penn, John and Habegger, Lukas and Blumenfeld, Andrew L. and Bai, Xiaodong and O'Keeffe, Sean and Yadav, Ashish and Praveen, Kavita and Jones, Marcus and Salerno, William J. and Chung, Wendy K. and Surakka, Ida and Willer, Cristen J. and Hveem, Kristian and Leader, Joseph B. and Carey, David J. and Ledbetter, David H. and Cardon, Lon and Yancopoulos, George D. and Economides, Aris and Coppola, Giovanni and Shuldiner, Alan R. and Balasubramanian, Suganthi and Cantor, Michael and Nelson, Matthew R. and Whittaker, John and Reid, Jeffrey G. and Marchini, Jonathan and Overton, John D. and Scott, Robert A. and Abecasis, Goncalo R. and Yerges-Armstrong, Laura M. and Baras, Aris},
  title     = {Exome sequencing and characterization of 49,960 individuals in the UK Biobank},
  series = {Nature : the international weekly journal of science},
  volume    = {586},
  journal   = {Nature : the international weekly journal of science},
  number    = {7831},
  publisher = {Macmillan Publishers Limited},
  address   = {London},
  organization    = {Regeneron Genetics Ctr},
  issn      = {0028-0836},
  doi       = {10.1038/s41586-020-2853-0},
  pages     = {749 -- 756},
  year      = {2020},
  abstract  = {The UK Biobank is a prospective study of 502,543 individuals, combining extensive phenotypic and genotypic data with streamlined access for researchers around the world(1). Here we describe the release of exome-sequence data for the first 49,960 study participants, revealing approximately 4 million coding variants (of which around 98.6\% have a frequency of less than 1\%). The data include 198,269 autosomal predicted loss-of-function (LOF) variants, a more than 14-fold increase compared to the imputed sequence. Nearly all genes (more than 97\%) had at least one carrier with a LOF variant, and most genes (more than 69\%) had at least ten carriers with a LOF variant. We illustrate the power of characterizing LOF variants in this population through association analyses across 1,730 phenotypes. In addition to replicating established associations, we found novel LOF variants with large effects on disease traits, includingPIEZO1on varicose veins,COL6A1on corneal resistance,MEPEon bone density, andIQGAP2andGMPRon blood cell traits. We further demonstrate the value of exome sequencing by surveying the prevalence of pathogenic variants of clinical importance, and show that 2\% of this population has a medically actionable variant. Furthermore, we characterize the penetrance of cancer in carriers of pathogenicBRCA1andBRCA2variants. Exome sequences from the first 49,960 participants highlight the promise of genome sequencing in large population-based studies and are now accessible to the scientific community. <br /> Exome sequences from the first 49,960 participants in the UK Biobank highlight the promise of genome sequencing in large population-based studies and are now accessible to the scientific community.},
  language  = {en}
}
@article{MoraskePenroseWyschkonetal.2018,
  author    = {Moraske, Svenja and Penrose, Anna and Wyschkon, Anne and Kohn, Juliane and Rauscher, Larissa and von Aster, Michael G. and Esser, G{\"u}nter},
  title     = {Pr{\"a}vention von Rechenst{\"o}rungen},
  series = {Kindheit und Entwicklung},
  volume    = {27},
  journal   = {Kindheit und Entwicklung},
  number    = {1},
  publisher = {Hogrefe},
  address   = {G{\"o}ttingen},
  issn      = {0942-5403},
  doi       = {10.1026/0942-5403/a000242},
  pages     = {31 -- 42},
  year      = {2018},
  abstract  = {Ziel ist die {\"U}berpr{\"u}fung der kurz- und mittelfristigen Wirksamkeit einer vorschulischen F{\"o}rderung des Mengen- und Zahlenverst{\"a}ndnisses bei Kindern mit einem Risiko f{\"u}r die Entwicklung einer Rechenst{\"o}rung. Es wurden 32 Risikokinder mit einer Kombination aus den F{\"o}rderprogrammen Mathematik im Vorschulalter und Mengen, z{\"a}hlen, Zahlen im letzten Kindergartenjahr von den Erzieherinnen trainiert und mit 38 untrainierten Risikokindern verglichen. Hinsichtlich der kurzfristigen Wirksamkeit zeigten sich positive Trainingseffekte auf die numerischen Leistungen im letzten Kindergartenjahr. Es ließen sich keine signifikanten mittelfristigen Trainingseffekte auf die Rechenleistungen im zweiten Halbjahr der 1. Klasse finden. Das eingesetzte vorschulische Pr{\"a}ventionsprogramm leistete danach einen wichtigen Beitrag zur kurzfristigen Verbesserung der mathematischen Basiskompetenzen.},
  language  = {de}
}
@article{LiStomaLottaetal.2020,
  author    = {Li, Chen and Stoma, Svetlana and Lotta, Luca A. and Warner, Sophie and Albrecht, Eva and Allione, Alessandra and Arp, Pascal P. and Broer, Linda and Buxton, Jessica L. and Boeing, Heiner and Langenberg, Claudia and Codd, Veryan},
  title     = {Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length},
  series = {American Journal of Human Genetics},
  volume    = {106},
  journal   = {American Journal of Human Genetics},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  pages     = {16},
  year      = {2020},
  abstract  = {Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 genomic regions at a false dicovery rate (FDR) < 0.05 threshold and prioritize genes at 31, with five highlighting nucleotide metabolism as an important regulator of LTL. We report six genome-wide significant loci in or near SENP7, MOB1B, CARMIL1 , PRRC2A, TERF2, and RFWD3, and our results support recently identified PARP1, POT1, ATM, and MPHOSPH6 loci. Phenome-wide analyses in >350,000 UK Biobank participants suggest that genetically shorter telomere length increases the risk of hypothyroidism and decreases the risk of thyroid cancer, lymphoma, and a range of proliferative conditions. Our results replicate previously reported associations with increased risk of coronary artery disease and lower risk for multiple cancer types. Our findings substantially expand current knowledge on genes that regulate LTL and their impact on human health and disease.},
  language  = {en}
}
@misc{LiStomaLottaetal.2020,
  author    = {Li, Chen and Stoma, Svetlana and Lotta, Luca A. and Warner, Sophie and Albrecht, Eva and Allione, Alessandra and Arp, Pascal P. and Broer, Linda and Buxton, Jessica L. and Boeing, Heiner and Langenberg, Claudia and Codd, Veryan},
  title     = {Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {3},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-52684},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-526843},
  pages     = {18},
  year      = {2020},
  abstract  = {Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including up to 78,592 individuals. We identify 49 genomic regions at a false dicovery rate (FDR) < 0.05 threshold and prioritize genes at 31, with five highlighting nucleotide metabolism as an important regulator of LTL. We report six genome-wide significant loci in or near SENP7, MOB1B, CARMIL1 , PRRC2A, TERF2, and RFWD3, and our results support recently identified PARP1, POT1, ATM, and MPHOSPH6 loci. Phenome-wide analyses in >350,000 UK Biobank participants suggest that genetically shorter telomere length increases the risk of hypothyroidism and decreases the risk of thyroid cancer, lymphoma, and a range of proliferative conditions. Our results replicate previously reported associations with increased risk of coronary artery disease and lower risk for multiple cancer types. Our findings substantially expand current knowledge on genes that regulate LTL and their impact on human health and disease.},
  language  = {en}
}
@phdthesis{Ganschow2021,
  author    = {Ganschow, Constantin Alexander},
  title     = {Die Konversion im Asylverfahren},
  series = {Acta Iuridica Universitatis Potsdamiensis},
  journal   = {Acta Iuridica Universitatis Potsdamiensis},
  number    = {7},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-509-5},
  issn      = {2199-9686},
  doi       = {10.25932/publishup-50581},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-505819},
  school      = {Universit{\"a}t Potsdam},
  pages     = {230},
  year      = {2021},
  abstract  = {Der Verfasser besch{\"a}ftigt sich mit der Frage des Glaubens{\"u}bertritts in einem Asylverfahren. Dabei nimmt er Zeitpunkt, Art und Umst{\"a}nde des Religionswechsels in den Blick. Ferner untersucht er, wie die sogenannte Konversion von den zust{\"a}ndigen Beh{\"o}rden und Gerichten zu behandeln und zu bewerten ist. Einf{\"u}hrend gibt er einen {\"U}berblick zum v{\"o}lkerrechtlichen Schutz der Religions- und Weltanschauungsfreiheit sowie typischen Gef{\"a}hrdungslagen. {\"U}berdies befasst er sich mit den Rechtsgrundlagen des Asyl- und Fl{\"u}chtlingsschutzrechts und stellt Verbindungen zum Flucht- und Verfolgungsgrund der Religion her. Schwerpunkt bildet die Untersuchung der Verfahrensstadien, in denen die Konversion relevant wird. Dabei ber{\"u}cksichtigt der Verfasser die nationale und europ{\"a}ische Rechtsprechung. Von besonderer Bedeutung sind die Ausf{\"u}hrungen zum Zusammenspiel von staatlichen Ermittlungspflichten und Mitwirkungsgeboten von Asylantragstellenden, wobei den Besonderheiten des grund- und menschenrechtlichen Mehrebenensystems Rechnung getragen wird. Zentral sind ferner die Ausf{\"u}hrungen zum Umgang mit Taufurkunden und sonstigen Bescheinigungen {\"u}ber die religi{\"o}se {\"U}berzeugung. Besonderes Gewicht liegt auf der verfassungsrechtlichen Stellung der Religionsgemeinschaften und der Frage, ob die Entscheidung einer Religionsgemeinschaft, ein neues Mitglied aufzunehmen, die Beh{\"o}rde im Asylverfahren bindet. Diesem Problem widmet sich der Verfasser unter Heranziehung der relevanten Literaturstimmen und einschl{\"a}gigen Rechtsprechung. Der rechtswissenschaftliche Beitrag bietet den beteiligten Akteuren nicht nur eine Einf{\"u}hrung in das Themengebiet des Glaubens{\"u}bertritts im Asylverfahren, sondern gibt den Lesenden auch eine praxistaugliche Handlungsunterst{\"u}tzung rund um die wichtigsten Fragen einer Konversion im Asylverfahren an die Hand. Praktische Bez{\"u}ge entstehen beispielsweise dadurch, dass wichtige Impulse und Empfehlungen f{\"u}r eine gleichermaßen moderne, rechtsstaatliche und grundrechtsorientierte Verfahrensf{\"u}hrung entwickelt werden.},
  language  = {de}
}
@misc{BiterovaEsmaeeliMoghaddamTabalvandaniAlanenetal.2018,
  author    = {Biterova, Ekaterina and Esmaeeli Moghaddam Tabalvandani, Mariam and Alanen, Heli I. and Saaranen, Mirva and Ruddock, Lloyd W.},
  title     = {Structures of Angptl3 and Angptl4},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {1048},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-46794},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-467943},
  pages     = {14},
  year      = {2018},
  abstract  = {Coronary artery disease is the most common cause of death globally and is linked to a number of risk factors including serum low density lipoprotein, high density lipoprotein, triglycerides and lipoprotein(a). Recently two proteins, angiopoietin-like protein 3 and 4, have emerged from genetic studies as being factors that significantly modulate plasma triglyceride levels and coronary artery disease. The exact function and mechanism of action of both proteins remains to be elucidated, however, mutations in these proteins results in up to 34\% reduction in coronary artery disease and inhibition of function results in reduced plasma triglyceride levels. Here we report the crystal structures of the fibrinogen-like domains of both proteins. These structures offer new insights into the reported loss of function mutations, the mechanisms of action of the proteins and open up the possibility for the rational design of low molecular weight inhibitors for intervention in coronary artery disease.},
  language  = {en}
}
@phdthesis{Schroeter2020,
  author    = {Schr{\"o}ter, Kai},
  title     = {Improved flood risk assessment},
  doi       = {10.25932/publishup-48024},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-480240},
  school      = {Universit{\"a}t Potsdam},
  pages     = {408},
  year      = {2020},
  abstract  = {Rivers have always flooded their floodplains. Over 2.5 billion people worldwide have been affected by flooding in recent decades. The economic damage is also considerable, averaging 100 billion US dollars per year. There is no doubt that damage and other negative effects of floods can be avoided. However, this has a price: financially and politically. Costs and benefits can be estimated through risk assessments. Questions about the location and frequency of floods, about the objects that could be affected and their vulnerability are of importance for flood risk managers, insurance companies and politicians. Thus, both variables and factors from the fields of hydrology and sociol-economics play a role with multi-layered connections. One example are dikes along a river, which on the one hand contain floods, but on the other hand, by narrowing the natural floodplains, accelerate the flood discharge and increase the danger of flooding for the residents downstream. Such larger connections must be included in the assessment of flood risk. However, in current procedures this is accompanied by simplifying assumptions. Risk assessments are therefore fuzzy and associated with uncertainties. This thesis investigates the benefits and possibilities of new data sources for improving flood risk assessment. New methods and models are developed, which take the mentioned interrelations better into account and also quantify the existing uncertainties of the model results, and thus enable statements about the reliability of risk estimates. For this purpose, data on flood events from various sources are collected and evaluated. This includes precipitation and flow records at measuring stations as well as for instance images from social media, which can help to delineate the flooded areas and estimate flood damage with location information. Machine learning methods have been successfully used to recognize and understand correlations between floods and impacts from a wide range of data and to develop improved models. Risk models help to develop and evaluate strategies to reduce flood risk. These tools also provide advanced insights into the interplay of various factors and on the expected consequences of flooding. This work shows progress in terms of an improved assessment of flood risks by using diverse data from different sources with innovative methods as well as by the further development of models. Flood risk is variable due to economic and climatic changes, and other drivers of risk. In order to keep the knowledge about flood risks up-to-date, robust, efficient and adaptable methods as proposed in this thesis are of increasing importance.},
  language  = {en}
}
@misc{MoraskePenroseWyschkonetal.2018,
  author    = {Moraske, Svenja and Penrose, Anna and Wyschkon, Anne and Kohn, Juliane and Rauscher, Larissa and von Aster, Michael G. and Esser, G{\"u}nter},
  title     = {Pr{\"a}vention von Rechenst{\"o}rungen},
  series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {616},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-43410},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-434101},
  pages     = {31 -- 42},
  year      = {2018},
  abstract  = {Ziel ist die {\"U}berpr{\"u}fung der kurz- und mittelfristigen Wirksamkeit einer vorschulischen F{\"o}rderung des Mengen- und Zahlenverst{\"a}ndnisses bei Kindern mit einem Risiko f{\"u}r die Entwicklung einer Rechenst{\"o}rung. Es wurden 32 Risikokinder mit einer Kombination aus den F{\"o}rderprogrammen Mathematik im Vorschulalter und Mengen, z{\"a}hlen, Zahlen im letzten Kindergartenjahr von den Erzieherinnen trainiert und mit 38 untrainierten Risikokindern verglichen. Hinsichtlich der kurzfristigen Wirksamkeit zeigten sich positive Trainingseffekte auf die numerischen Leistungen im letzten Kindergartenjahr. Es ließen sich keine signifikanten mittelfristigen Trainingseffekte auf die Rechenleistungen im zweiten Halbjahr der 1. Klasse finden. Das eingesetzte vorschulische Pr{\"a}ventionsprogramm leistete danach einen wichtigen Beitrag zur kurzfristigen Verbesserung der mathematischen Basiskompetenzen.},
  language  = {de}
}
@article{HoeseWyschkonMoraskeetal.2016,
  author    = {H{\"o}se, Anna and Wyschkon, Anne and Moraske, Svenja and Eggeling, Marie and Quandte, Sabine and Kohn, Juliane and Poltz, Nadine and von Aster, Michael G. and Esser, G{\"u}nter},
  title     = {Prevention of dyslexia short-term and intermediate effects of promoting phonological awareness and letter-sound correspondence with at-risk preschool children},
  series = {Zeitschrift f{\~A}¼r Kinder- und Jugendpsychiatrie und Psychotherapie},
  volume    = {44},
  journal   = {Zeitschrift f{\~A}¼r Kinder- und Jugendpsychiatrie und Psychotherapie},
  publisher = {Hogrefe},
  address   = {Bern},
  issn      = {1422-4917},
  doi       = {10.1024/1422-4917/a000456},
  pages     = {377 -- 391},
  year      = {2016},
  abstract  = {Objective: This study assesses the short-term and intermediate effects of preschool training stimulating phonological awareness and letter-sound correspondence for children at risk of developing dyslexia. Moreover, we examined whether training reduced the frequency of subsequent dyslexic problems. Method: 25 children at risk of developing dyslexia were trained with Horen, Lauschen, Lernen 1 und 2 (Kuspert \& Schneider, 2008; Plume \& Schneider, 2004) by their kindergarten teachers and were compared with 60 untrained at-risk children. Results:The training revealed a significant short-term effect: The phonological awareness of trained at-risk children increased significantly over that of untrained at-risk children. However, there were no differences in phonological awareness, spelling, and reading ability between the first-graders in the training and control group. Furthermore, reading problems were reduced in the training group. Conclusions: In the future, phonological awareness as well as additional predictors should be included when identifying children vulnerable to developing dyslexia. Moreover, in order to prevent dyslexia, additional prerequisite deficits need to be identified, alleviated, and their effects evaluated.},
  language  = {de}
}
@misc{KreibichMuellerSchroeteretal.2017,
  author    = {Kreibich, Heidi and M{\"u}ller, Meike and Schr{\"o}ter, Kai and Thieken, Annegret},
  title     = {New insights into flood warning reception and emergency response by affected parties},
  series = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Mathematisch-Naturwissenschaftliche Reihe},
  number    = {659},
  issn      = {1866-8372},
  doi       = {10.25932/publishup-41838},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-418381},
  pages     = {18},
  year      = {2017},
  abstract  = {Flood damage can be mitigated if the parties at risk are reached by flood warnings and if they know how to react appropriately. To gain more knowledge about warning reception and emergency response of private households and companies, surveys were undertaken after the August 2002 and the June 2013 floods in Germany. Despite pronounced regional differences, the results show a clear overall picture: in 2002, early warnings did not work well; e.g. many households (27 \%) and companies (45 \%) stated that they had not received any flood warnings. Additionally, the preparedness of private households and companies was low in 2002, mainly due to a lack of flood experience. After the 2002 flood, many initiatives were launched and investments undertaken to improve flood risk management, including early warnings and an emergency response in Germany. In 2013, only a small share of the affected households (5 \%) and companies (3 \%) were not reached by any warnings. Additionally, private households and companies were better prepared. For instance, the share of companies which have an emergency plan in place has increased from 10\% in 2002 to 34\% in 2013. However, there is still room for improvement, which needs to be triggered mainly by effective risk and emergency communication. The challenge is to continuously maintain and advance an integrated early warning and emergency response system even without the occurrence of extreme floods.},
  language  = {en}
}
@misc{MoserTschakertMuelleretal.2015,
  author    = {Moser, Othmar and Tschakert, Gerhard and Mueller, Alexander and Groeschl, Werner and Pieber, Thomas R. and Obermayer-Pietsch, Barbara and Koehler, Gerd and Hofmann, Peter},
  title     = {Effects of high-intensity interval exercise versus moderate continuous exercise on glucose homeostasis and hormone response in patients with type 1 diabetes mellitus using novel ultra-long-acting insulin},
  series = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  journal   = {Postprints der Universit{\"a}t Potsdam : Humanwissenschaftliche Reihe},
  number    = {497},
  issn      = {1866-8364},
  doi       = {10.25932/publishup-40834},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-408342},
  pages     = {17},
  year      = {2015},
  abstract  = {Introduction We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for mean load and duration in type 1 diabetes mellitus (T1DM). Material and Methods Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A) and above (B) the first lactate turn point and below the second lactate turn point (C) on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/Novo Nordisk, Denmark). Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25\% (A), 50\% (B), and 75\% (C) dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system. Results BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006) and B (p = 0.004) and respiratory exchange ratio for A (p = 0.003) and B (p = 0.003) were significantly higher compared to CON but not for C. Conclusion Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM.},
  language  = {en}
}
@phdthesis{Kox2018,
  author    = {Kox, Thomas},
  title     = {Perception and use of uncertainty in severe weather warnings},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-411541},
  school      = {Universit{\"a}t Potsdam},
  pages     = {154},
  year      = {2018},
  abstract  = {Uncertainty is an essential part of atmospheric processes and thus inherent to weather forecasts. Nevertheless, weather forecasts and warnings are still predominately issued as deterministic (yes or no) forecasts, although research suggests that providing weather forecast users with additional information about the forecast uncertainty can enhance the preparation of mitigation measures. Communicating forecast uncertainty would allow for a provision of information on possible future events at an earlier time. The desired benefit is to enable the users to start with preparatory protective action at an earlier stage of time based on the their own risk assessment and decision threshold. But not all users have the same threshold for taking action. In the course of the project WEXICOM ('Wetterwarnungen: Von der Extremereignis-Information zu Kommunikation und Handlung') funded by the Deutscher Wetterdienst (DWD), three studies were conducted between the years 2012 and 2016 to reveal how weather forecasts and warnings are reflected in weather-related decision-making. The studies asked which factors influence the perception of forecasts and the decision to take protective action and how forecast users make sense of probabilistic information and the additional lead time. In a first exploratory study conducted in 2012, members of emergency services in Germany were asked questions about how weather warnings are communicated to professional endusers in the emergency community and how the warnings are converted into mitigation measures. A large number of open questions were selected to identify new topics of interest. The questions covered topics like users' confidence in forecasts, their understanding of probabilistic information as well as their lead time and decision thresholds to start with preparatory mitigation measures. Results show that emergency service personnel generally have a good sense of uncertainty inherent in weather forecasts. Although no single probability threshold could be identified for organisations to start with preparatory mitigation measures, it became clear that emergency services tend to avoid forecasts based on low probabilities as a basis for their decisions. Based on this findings, a second study conducted with residents of Berlin in 2014 further investigated the question of decision thresholds. The survey questions related to the topics of the perception of and prior experience with severe weather, trustworthiness of forecasters and confidence in weather forecasts, and socio-demographic and social-economic characteristics. Within the questionnaire a scenario was created to determine individual decision thresholds and see whether subgroups of the sample lead to different thresholds. The results show that people's willingness to act tends to be higher and decision thresholds tend to be lower if the expected weather event is more severe or the property at risk is of higher value. Several influencing factors of risk perception have significant effects such as education, housing status and ability to act, whereas socio-demographic determinants alone are often not sufficient to fully grasp risk perception and protection behaviour. Parallel to the quantitative studies, an interview study was conducted with 27 members of German civil protection between 2012 and 2016. The results show that the latest developments in (numerical) weather forecasting do not necessarily fit the current practice of German emergency services. These practices are mostly carried out on alarms and ground truth in a reactive manner rather than on anticipation based on prognosis or forecasts. As the potential consequences rather than the event characteristics determine protective action, the findings support the call and need for impact-based warnings. Forecasters will rely on impact data and need to learn the users' understanding of impact. Therefore, it is recommended to enhance weather communication not only by improving computer models and observation tools, but also by focusing on the aspects of communication and collaboration. Using information about uncertainty demands awareness about and acceptance of the limits of knowledge, hence, the capabilities of the forecaster to anticipate future developments of the atmosphere and the capabilities of the user to make sense of this information.},
  language  = {en}
}
@book{Wipper2011,
  author    = {Wipper, Alexander},
  title     = {Flugverkehr und Risikodiskurs},
  publisher = {Universit{\"a}tsverlag Potsdam},
  address   = {Potsdam},
  isbn      = {978-3-86956-136-3},
  issn      = {0934-716X},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-49533},
  publisher      = {Universit{\"a}t Potsdam},
  pages     = {58},
  year      = {2011},
  abstract  = {F{\"u}r den Flugverkehr als Teil eines regional und global verdichteten Infrastruktursystems sind Naturgefahren wie Vulkanausbr{\"u}che gleichbedeutend mit Risiken. Die Kommunikation von Risiken verl{\"a}uft im Spannungsfeld von wirtschaftlichen und staatlichen Akteuren einerseits und Medien und Zivilgesellschaft andererseits. Demgegen{\"u}ber stehen Modelle diskursiver Risikoregulierung als Instrumente {\"o}ffentlicher Aushandlungsprozesse. Diskutiert werden Einflussfaktoren auf Entscheidungen im Kontext von Risikodiskursen. Dabei wird insbesondere die Funktionslogik der Medien untersucht. Am Beispiel der Aschewolke des Eyjafjallaj{\"o}kull 2010 wird die Ph{\"a}nomenkonstellation von Akteuren und Diskurspositionen illustriert und der Verlauf einer medialen Risikoentwicklung nachgezeichnet.},
  language  = {de}
}
@phdthesis{Meissner2007,
  author    = {Meißner, Frank},
  title     = {Produktion unter Risiko},
  url       = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus-18810},
  school      = {Universit{\"a}t Potsdam},
  year      = {2007},
  abstract  = {Mit der hier vorliegenden Arbeit wird ein mikro{\"o}konomisches Multiagentenmodell eines Produktionssektors vorgeschlagen. Das Modell folgt einem post-walrasianischem Ungleichgewichtsansatz und beschreibt optimierende Agenten der Produktionsseite. Diese ber{\"u}cksichtigen in probabilistischen Nebenbedingungen Risiken des Cash Flow, die sich aus unsicheren Absatzmengen ergeben. Produzenten stehen in monopolistischer Konkurrenz und lernen durch Beobachten. Wird vorliegendes Modell in ein Totalmodell integriert, so wird es m{\"o}glich, die sich aus der Klimadebatte ergebenden, notwendigen Ver{\"a}nderungen im Investitions- und Produktionsverhalten zu diskutieren und darzustellen.},
  language  = {de}
}