@article{GemeinholzerMayRistowetal.2012,
  author    = {Gemeinholzer, B. and May, F. and Ristow, Michael and Batsch, C. and Lauterbach, D.},
  title     = {Strong genetic differentiation on a fragmentation gradient among populations of the heterocarpic annual Catananche lutea L. (Asteraceae)},
  series = {Plant systematics and evolution},
  volume    = {298},
  journal   = {Plant systematics and evolution},
  number    = {8},
  publisher = {Springer},
  address   = {Wien},
  issn      = {0378-2697},
  doi       = {10.1007/s00606-012-0661-1},
  pages     = {1585 -- 1596},
  year      = {2012},
  abstract  = {In landscapes which are predominately characterised by agriculture, natural ecosystems are often reduced to a mosaic of scattered patches of natural vegetation. Species with formerly connected distribution ranges now have restricted gene flow among populations. This has isolating effects upon population structure, because species are often confined by their limited dispersal capabilities. In this study, we test the effects of habitat fragmentation, precipitation, and isolation of populations on the genetic structure (AFLP) and fitness of the Asteraceae Catananche lutea. Our study area is an agro-dominated ecosystem in the desert-Mediterranean transition zone of the Southern Judea Lowlands in Israel. Our analysis revealed an intermediate level of intra-population genetic diversity across the study site with reduced genetic diversity on smaller scale. Although the size of the whole study area was relatively small (20 x 45 km), we found isolation by distance to be effective. We detected a high level of genetic differentiation among populations but genetic structure did not reflect spatial patterns. Population genetic diversity was correlated neither with position along the precipitation gradient nor with different seed types or other plant fitness variables in C. lutea.},
  language  = {en}
}
@article{EilersKleineEckertetal.2021,
  author    = {Eilers, Elisabeth Johanna and Kleine, Sandra and Eckert, Silvia and Waldherr, Simon and M{\"u}ller, Caroline},
  title     = {Flower production, headspace volatiles, pollen nutrients, and florivory in tanacetum vulgare chemotypes},
  series = {Frontiers in plant science : FPLS},
  volume    = {11},
  journal   = {Frontiers in plant science : FPLS},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-462X},
  doi       = {10.3389/fpls.2020.611877},
  pages     = {17},
  year      = {2021},
  abstract  = {Floral volatiles and reward traits are major drivers for the behavior of mutualistic as well as antagonistic flower visitors, i.e., pollinators and florivores. These floral traits differ tremendously between species, but intraspecific differences and their consequences on organism interactions remain largely unknown. Floral volatile compounds, such as terpenoids, function as cues to advertise rewards to pollinators, but should at the same time also repel florivores. The reward composition, e.g., protein and lipid contents in pollen, differs between individuals of distinct plant families. Whether the nutritional value of rewards within the same plant species is linked to their chemotypes, which differ in their pattern of specialized metabolites, has yet not been investigated. In the present study, we compared Tanacetum vulgare plants of five terpenoid chemotypes with regard to flower production, floral headspace volatiles, pollen macronutrient and terpenoid content, and floral attractiveness to florivorous beetles. Our analyses revealed remarkable differences between the chemotypes in the amount and diameter of flower heads, duration of bloom period, and pollen nutritional quality. The floral headspace composition of pollen-producing mature flowers, but not of premature flowers, was correlated to that of pollen and leaves in the same plant individual. For two chemotypes, florivorous beetles discriminated between the scent of mature and premature flower heads and preferred the latter. In semi-field experiments, the abundance of florivorous beetles and flower tissue miners differed between T. vulgare chemotypes. Moreover, the scent environment affected the choice and beetles were more abundant in homogenous plots composed of one single chemotype than in plots with different neighboring chemotypes. In conclusion, flower production, floral metabolic composition and pollen quality varied to a remarkable extend within the species T. vulgare, and the attractiveness of floral scent differed also intra-individually with floral ontogeny. We found evidence for a trade-off between pollen lipid content and pollen amount on a per-plant-level. Our study highlights that chemotypes which are more susceptible to florivory are less attacked when they grow in the neighborhood of other chemotypes and thus gain a benefit from high overall chemodiversity.},
  language  = {en}
}
@article{KeruboMidiwoDereseetal.2013,
  author    = {Kerubo, Leonidah Omosa and Midiwo, Jacob Ogweno and Derese, Solomon and Langat, Moses K. and Akala, Hoseah M. and Waters, Norman C. and Peter, Martin and Heydenreich, Matthias},
  title     = {Antiplasmodial activity of compounds from the surface exudates of senecio roseiflorus},
  series = {Natural product communications : an international journal for communications and reviews},
  volume    = {8},
  journal   = {Natural product communications : an international journal for communications and reviews},
  number    = {2},
  publisher = {NPC},
  address   = {Westerville},
  issn      = {1934-578X},
  pages     = {175 -- 176},
  year      = {2013},
  abstract  = {From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic analysis. The surface exudate and the flavonoids isolated showed moderate to good antiplasmodial activity with 5,4'-dihydroxy-7-dimethoxyflavanone having the highest activity against chloroquine-sensitive (D6) and resistant (W2) strains of Plasmodium falciparum, with IC50 values of 3.2 +/- 0.8 and 4.4 +/- 0.01 mu g/mL respectively.},
  language  = {en}
}
@article{MachumiYenesewMidiwoetal.2012,
  author    = {Machumi, Francis and Yenesew, Abiy and Midiwo, Jacob O. and Heydenreich, Matthias and Kleinpeter, Erich and Tekwani, Babu L. and Khan, Shabana I. and Walker, Larry A. and Muhammad, Ilias},
  title     = {Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus},
  series = {Natural product communications : an international journal for communications and reviews},
  volume    = {7},
  journal   = {Natural product communications : an international journal for communications and reviews},
  number    = {9},
  publisher = {NPC},
  address   = {Westerville},
  issn      = {1934-578X},
  pages     = {1123 -- 1126},
  year      = {2012},
  abstract  = {The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine sensitive D6 (IC50 9.7 mu g/mL) and chloroquine resistant W2 (IC50 15.0 mu g/mL) strains of Plasmodium falciparum. Seventeen secondary metabolites were isolated from the extract through conventional chromatographic techniques and identified using various spectroscopic methods. The compounds were evaluated for their in vitro antiplasmodial, antileishmanial and anticancer activities revealing activity of four carvotacetone derivatives, namely 3-acetoxy-7-hydroxy-5-tigloyloxycarvotacetone (1) 3,7-dihydroxy-5-tigloyloxycarvotacetone (2), 3-acetoxy-5,7-dihydroxycarvotacetone (3) and 3,5,7-trihydroxycarvotacetone (4); with antiplasmodial IC50 values of 1.40, 0.79, 0.60 and 3.40 mu g/mL, respectively, against chloroquine sensitive D6 strains of P. falciparum; antiplasmodial activity of IC50 2.00, 0.90, 0.68 and 2.80 mu g/mL respectively, against chloroquine resistant W2 strains of P. falciparum, antileishmanial IC50, values of 0.70, 3.00, 0.70 and 17.00 mu g/mL, respectively, against the parasite L. donovanii promastigotes, and anticancer activity against human SK-MEL, KB, BT-549 and SK-OV-3 tumor cells, with IC50 values between <1.1 - 5.3 mu g/mL, for 1-3. In addition, cytotoxic effects of the active compounds were evaluated against monkey kidney fibroblasts (VERO) and pig kidney epithelial cells (LLC-PK11). The structures of carvotacetone derivatives were determined by ID and 2D NMR spectroscopy; the absolute stereochemical configuration of 3-acetoxy-7-hydroxy-5-tigloyloxycarvotacetone (I) was determined as 3R, 4R, 5S by circular dichroism, specific rotation, H-1 NMR and 2D NMR ROESY and NOESY experiments.},
  language  = {en}
}
@article{AudisioClineSolanoetal.2014,
  author    = {Audisio, Paolo and Cline, Andrew R. and Solano, Emanuela and Mancini, Emiliano and Lamanna, Francesco and Antonini, Gloria and Trizzino, Marco},
  title     = {A peculiar new genus and species of pollen-beetle (Coleoptera, Nitidulidae) from eastern Africa, with a molecular phylogeny of related Meligethinae},
  series = {Systematics and biodiversity},
  volume    = {12},
  journal   = {Systematics and biodiversity},
  number    = {1},
  publisher = {Routledge, Taylor \& Francis Group},
  address   = {Abingdon},
  issn      = {1477-2000},
  doi       = {10.1080/14772000.2013.877539},
  pages     = {77 -- 91},
  year      = {2014},
  language  = {en}
}