@article{SalzwedelWegscheiderSchulzBehrendtetal.2019, author = {Salzwedel, Annett and Wegscheider, Karl and Schulz-Behrendt, Claudia and D{\"o}rr, Gesine and Reibis, Rona Katharina and V{\"o}ller, Heinz}, title = {No impact of an extensive social intervention program on return to work and quality of life after acute cardiac event: a cluster-randomized trial in patients with negative occupational prognosis}, series = {International archives of occupational and environmental health}, volume = {92}, journal = {International archives of occupational and environmental health}, number = {8}, publisher = {Springer}, address = {New York}, issn = {0340-0131}, doi = {10.1007/s00420-019-01450-3}, pages = {1109 -- 1120}, year = {2019}, abstract = {Objectives To examine the effectiveness of extensive social therapy intervention during inpatient multi-component cardiac rehabilitation (CR) on return to work and quality of life in patients with low probability of work resumption after an acute cardiac event. Methods Patients after acute cardiac event with negative subjective expectations about return to work or unemployment (n = 354) were included and randomized in clusters of 3-6 study participants. Clusters were randomized for social counseling and therapy led by a social worker, six sessions of 60 min each in 3 weeks, or control group (usual care: individual counseling meeting by request). The return to work (RTW) status and change in quality of life (QoL, short form 12: Physical and Mental Component Summary PCS and MCS) 12 months after discharge from inpatient CR were outcome measures. Results The regression model for RTW showed no impact of the intervention (OR 1.1, 95\% CI 0.6-2.1, P = 0.79; n = 263). Predictors were unemployment prior to CR as well as higher anxiety values at discharge from CR. Likewise, QoL was not improved by social therapy (linear mixed model: Delta PCS 0.3, 95\% CI - 1.9 to 2.5; P = 0.77; n = 177; Delta MCS 0.7, 95\% CI - 1.9 to 3.3; P = 0.58; n = 215). Conclusions In comparison to usual care, an intensive program of social support for patients during inpatient cardiac rehabilitation after an acute cardiac event had no additional impact on either the rate of resuming work or quality of life.}, language = {en} } @article{SalzwedelReibisHeidleretal.2019, author = {Salzwedel, Annett and Reibis, Rona Katharina and Heidler, Maria-Dorothea and Wegscheider, Karl and V{\"o}ller, Heinz}, title = {Determinants of Return to Work After Multicomponent Cardiac Rehabilitation}, series = {Archives of Physical Medicine and Rehabilitation}, volume = {100}, journal = {Archives of Physical Medicine and Rehabilitation}, number = {12}, publisher = {Elsevier}, address = {Philadelphia}, issn = {0003-9993}, doi = {10.1016/j.apmr.2019.04.003}, pages = {2399 -- 2402}, year = {2019}, abstract = {Objectives: To explore predictors of return to work in patients after acute coronary syndrome and coronary artery bypass grafting, taking into account cognitive performance, depression, physical capacity, and self-assessment of the occupational prognosis. Design: Observational, prospective, bicentric. Setting: Postacute 3-week inpatient cardiac rehabilitation (CR). Participants: Patients (N=401) <65 years of age (mean 54.5 +/- 6.3y), 80\% men. Interventions: Not applicable. Main Outcome Measures: Status of return to work (RTW) 6 months after discharge from CR. Results: The regression model for RTW showed negative associations for depression (odds ratio 0.52 per SD, 95\% confidence interval 0.36-0.76, P=.001), age (odds ratio 0.72, 95\% confidence interval 0.52-1.00, P=.047), and in particular for a negative subjective occupational prognosis (expected incapacity for work odds ratio 0.19, 95\% confidence interval 0.06-0.59, P=.004; unemployment odds ratio 0.08, 95\% confidence interval 0.01-0.72, P=.024; retirement odds ratio 0.07, 95\% confidence interval 0.01-0.067, P=.021). Positive predictors were employment before the cardiac event (odds ratio 9.66, 95\% confidence interval 3.10-30.12, P<.001), capacity to work (fit vs unfit) at discharge from CR (odds ratio 3.15, 95\% confidence interval 1.35-7.35, P=.008), and maximum exercise capacity (odds ratio 1.49, 95\% confidence interval 1.06-2.11, P=.022). Cognitive performance had no effect.}, language = {en} } @misc{PolzinRassafBoehmetal.2013, author = {Polzin, Amin and Rassaf, Tienush and Boehm, Andreas and Lueth, Anja and Kleuser, Burkhard and Zeus, Tobias and Kelm, Malte and Kroemer, Heyo K. and Schroer, Karsten and Rauch, Bernhard H.}, title = {Aspirin inhibits release of platelet-derived sphingosine-1-phosphate in acute myocardial infarction}, series = {INTERNATIONAL JOURNAL OF CARDIOLOGY}, volume = {170}, journal = {INTERNATIONAL JOURNAL OF CARDIOLOGY}, number = {2}, publisher = {ELSEVIER IRELAND LTD}, address = {CLARE}, issn = {0167-5273}, doi = {10.1016/j.ijcard.2013.10.050}, pages = {E23 -- E24}, year = {2013}, language = {en} }