@article{Yarman2017,
  author    = {Yarman, Aysu},
  title     = {Development of a molecularly imprinted polymer-based electrochemical sensor for tyrosinase},
  series = {Turkish journal of chemistry},
  volume    = {42},
  journal   = {Turkish journal of chemistry},
  number    = {2},
  publisher = {T{\"u}rkiye Bilimsel ve Teknik Ara{\c{s}}t{\i}rma Kurumu},
  address   = {Ankara},
  issn      = {1300-0527},
  doi       = {10.3906/kim-1708-68},
  pages     = {346 -- 354},
  year      = {2017},
  abstract  = {For the first time a molecularly imprinted polymer (MIP)-based sensor for tyrosinase is described. This sensor is based on the electropolymerization of scopoletin or o-phenylenediamine in the presence of tyrosinase from mushrooms, which has a high homology to the human enzyme. The template was removed either by treatment with proteinase Kor by alkaline treatment. The measuring signal was generated either by measuring the formation of a product by the target enzyme or by evaluation of the permeability of the redox marker ferricyanide. The o-phenylenediamine-based MIP sensor has a linear measuring range up to 50 nM of tyrosinase with a limit of detection of 3.97 nM (R 2 = 0.994) and shows good discrimination towards other proteins, e.g., bovine serum albumin and cytochrome c.},
  language  = {en}
}