@phdthesis{Arend2024, author = {Arend, Marius}, title = {Comparing genome-scale models of protein-constrained metabolism in heterotrophic and photosynthetic microorganisms}, doi = {10.25932/publishup-65147}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-651470}, school = {Universit{\"a}t Potsdam}, pages = {150}, year = {2024}, abstract = {Genome-scale metabolic models are mathematical representations of all known reactions occurring in a cell. Combined with constraints based on physiological measurements, these models have been used to accurately predict metabolic fluxes and effects of perturbations (e.g. knock-outs) and to inform metabolic engineering strategies. Recently, protein-constrained models have been shown to increase predictive potential (especially in overflow metabolism), while alleviating the need for measurement of nutrient uptake rates. The resulting modelling frameworks quantify the upkeep cost of a certain metabolic flux as the minimum amount of enzyme required for catalysis. These improvements are based on the use of in vitro turnover numbers or in vivo apparent catalytic rates of enzymes for model parameterization. In this thesis several tools for the estimation and refinement of these parameters based on in vivo proteomics data of Escherichia coli, Saccharomyces cerevisiae, and Chlamydomonas reinhardtii have been developed and applied. The difference between in vitro and in vivo catalytic rate measures for the three microorganisms was systematically analyzed. The results for the facultatively heterotrophic microalga C. reinhardtii considerably expanded the apparent catalytic rate estimates for photosynthetic organisms. Our general finding pointed at a global reduction of enzyme efficiency in heterotrophy compared to other growth scenarios. Independent of the modelled organism, in vivo estimates were shown to improve accuracy of predictions of protein abundances compared to in vitro values for turnover numbers. To further improve the protein abundance predictions, machine learning models were trained that integrate features derived from protein-constrained modelling and codon usage. Combining the two types of features outperformed single feature models and yielded good prediction results without relying on experimental transcriptomic data. The presented work reports valuable advances in the prediction of enzyme allocation in unseen scenarios using protein constrained metabolic models. It marks the first successful application of this modelling framework in the biotechnological important taxon of green microalgae, substantially increasing our knowledge of the enzyme catalytic landscape of phototrophic microorganisms.}, language = {en} } @article{LunaKorup2022, author = {Luna, Lisa and Korup, Oliver}, title = {Seasonal landslide activity lags annual precipitation pattern in the Pacific Northwest}, series = {Geophysical research letters}, volume = {49}, journal = {Geophysical research letters}, number = {18}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {0094-8276}, doi = {10.1029/2022GL098506}, pages = {11}, year = {2022}, abstract = {Seasonal variations in landslide activity remain understudied compared to recent advances in landslide early warning at hourly to daily timescales. Here, we learn the seasonal pattern of monthly landslide activity in the Pacific Northwest from five heterogeneous landslide inventories with differing spatial and temporal coverage and reporting protocols combined in a Bayesian multi-level model. We find that landslide activity is distinctly seasonal, with credible increases in landslide intensity, inter-annual variability, and probability marking the onset of the landslide season in November. Peaks in landslide probability in January and intensity in February lag the annual peak in mean monthly precipitation and landslide activity is more variable in winter than in summer, when landslides are rare. For a given monthly rainfall, landslide intensity at the season peak in February is up to 10 times higher than at the onset in November, underlining the importance of antecedent seasonal hillslope conditions.}, language = {en} } @article{LachmairFischerGerjets2022, author = {Lachmair, Martin and Fischer, Martin H. and Gerjets, Peter}, title = {Action-control mappings of interfaces in virtual reality: a study of embodied interaction}, series = {Frontiers in virtual reality}, volume = {3}, journal = {Frontiers in virtual reality}, publisher = {Frontiers Media}, address = {Lausanne}, issn = {2673-4192}, doi = {10.3389/frvir.2022.976849}, pages = {11}, year = {2022}, abstract = {The development of interface technologies is driven by the goal of making interaction more positive through natural action-control mappings. In Virtual Reality (VR), the entire body is potentially involved for interaction, using such mappings with a maximum of degrees of freedom. The downside is the increase in interaction complexity, which can dramatically influence interface design. A cognitive perspective on detailed aspects of interaction patterns is lacking in common interface design guidelines, although it can be helpful to make this complexity controllable and, thus, make interaction behavior predictable. In the present study, the distinction between grounding, embodiment, and situatedness (the GES framework) is applied to organize aspects of interactions and to compare them with each other. In two experiments, zooming into or out of emotional pictures through changes of arm span was examined in VR. There are qualitatively different aspects during such an interaction: i) perceptual aspects caused by zooming are fundamental for human behavior (Grounding: closer objects appear bigger) and ii) aspects of gestures correspond to the physical characteristics of the agents (Embodiment: little distance of hands signals little or, in contrast, "creating more detail"). The GES-framework sets aspects of Grounding against aspects of Embodiment, thus allowing to predict human behavior regarding these qualitatively different aspects. For the zooming procedure, the study shows that Grounding can overrule Embodiment in interaction design. Thus, we propose GES as a cognitive framework that can help to inform interaction guidelines for user interface design in VR.}, language = {en} } @article{RuszkiewiczPapatheodorouJaecketal.2023, author = {Ruszkiewicz, Joanna and Papatheodorou, Ylea and J{\"a}ck, Nathalie and Melzig, Jasmin and Eble, Franziska and Pirker, Annika and Thomann, Marius and Haberer, Andreas and Rothmiller, Simone and B{\"u}rkle, Alexander and Mangerich, Aswin}, title = {NAD+ Acts as a protective factor in cellular stress response to DNA alkylating agents}, series = {Cells : open access journal}, volume = {12}, journal = {Cells : open access journal}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {2073-4409}, doi = {10.3390/cells12192396}, pages = {22}, year = {2023}, abstract = {Sulfur mustard (SM) and its derivatives are potent genotoxic agents, which have been shown to trigger the activation of poly (ADP-ribose) polymerases (PARPs) and the depletion of their substrate, nicotinamide adenine dinucleotide (NAD+). NAD+ is an essential molecule involved in numerous cellular pathways, including genome integrity and DNA repair, and thus, NAD+ supplementation might be beneficial for mitigating mustard-induced (geno)toxicity. In this study, the role of NAD+ depletion and elevation in the genotoxic stress response to SM derivatives, i.e., the monofunctional agent 2-chloroethyl-ethyl sulfide (CEES) and the crosslinking agent mechlorethamine (HN2), was investigated with the use of NAD+ booster nicotinamide riboside (NR) and NAD+ synthesis inhibitor FK866. The effects were analyzed in immortalized human keratinocytes (HaCaT) or monocyte-like cell line THP-1. In HaCaT cells, NR supplementation, increased NAD+ levels, and elevated PAR response, however, did not affect ATP levels or DNA damage repair, nor did it attenuate long- and short-term cytotoxicities. On the other hand, the depletion of cellular NAD+ via FK866 sensitized HaCaT cells to genotoxic stress, particularly CEES exposure, whereas NR supplementation, by increasing cellular NAD+ levels, rescued the sensitizing FK866 effect. Intriguingly, in THP-1 cells, the NR-induced elevation of cellular NAD+ levels did attenuate toxicity of the mustard compounds, especially upon CEES exposure. Together, our results reveal that NAD+ is an important molecule in the pathomechanism of SM derivatives, exhibiting compound-specificity. Moreover, the cell line-dependent protective effects of NR are indicative of system-specificity of the application of this NAD+ booster.}, language = {en} } @article{SaguTchewonpiRawelRohn2022, author = {Sagu Tchewonpi, Sorel and Rawel, Harshadrai M. and Rohn, Sascha}, title = {Targeted bottom-up mass spectrometry approach for the relative quantification of post-translational modification of bovine κ-casein during milk fermentation}, series = {Molecules}, volume = {27}, journal = {Molecules}, number = {18}, publisher = {MDPI}, address = {Basel}, issn = {1420-3049}, doi = {10.3390/molecules27185834}, pages = {17}, year = {2022}, abstract = {kappa-casein (kappa-CN) is one of the key components in bovine milk, playing a unique role in the structuration of casein micelles. It contains in its chemical structure up to sixteen amino acid residues (mainly serine and threonine) susceptible to modifications, including glycosylation and phosphorylation, which may further be formed during milk processing. In this study, changes in post-translational modification (PTM) of kappa-CN during bovine milk fermentation were investigated. One-to-five-day fermented milk samples were produced. A traditional bottom-up proteomics approach was used to establish a multiple-reaction monitoring (MRM) method for relative quantification of kappa-CN PTM. Endoproteinase Glu-C was found to efficiently digest the kappa-CN molecule. The developed LC-MS method was validated by performing assessments of linearity, precision, repeatability, reproducibility, limit of detection (LOD), and limit of quantification (LOQ). Among the yielded peptides, four of them containing serine and threonine residues were identified and the unmodified as well as the modified variants of each of them were relatively quantified. These peptides were (1) IPTINTIASGEPTSTTE ([140, 158]), (2) STVATLE ([162, 168]), (3) DSPE ([169, 172]), and (4) INTVQVTSTAV ([180, 190]). Distribution analysis between unmodified and modified peptides revealed that over 50\% of kappa-CN was found in one of its modified forms in milk. The fermentation process further significantly altered the composition between unmodified/modified kappa-CN, with glycoslaytion being predominant compared to phosphorylation (p < 0.01). Further method development towards alpha and beta-CN fractions and their PTM behavior would be an asset to better understand the changes undergone by milk proteins and the micellar structure during fermentation.}, language = {en} } @misc{HorvatWienerSchmelingetal.2022, author = {Horvat, Anja Kranjc and Wiener, Jeff and Schmeling, Sascha Marc and Borowski, Andreas}, title = {What does the curriculum say? Review of the particle physics content in 27 high-school physics curricula}, series = {Physics}, volume = {4}, journal = {Physics}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {2624-8174}, doi = {10.3390/physics4040082}, pages = {1278 -- 1298}, year = {2022}, abstract = {This international curricular review provides a structured overview of the particle physics content in 27 state, national, and international high-school physics curricula. The review was based on a coding manual that included 60 concepts that were identified as relevant for high-school particle physics education. Two types of curricula were reviewed, namely curricula with a dedicated particle physics chapter and curricula without a dedicated particle physics chapter. The results of the curricular review show that particle physics concepts are explicitly or implicitly present in all reviewed curricula. However, the number of particle physics concepts that are featured in a curriculum varies greatly across the reviewed curricula. We identified core particle physics concepts that can be found in most curricula. Here, elementary particles, fundamental interactions, and charges were identified as explicit particle physics concepts that are featured in more than half of the reviewed curricula either as content or context. Indeed, theoretical particle physics concepts are more prominent in high-school physics curricula than experimental particle physics concepts. Overall, this international curricular review provides the basis for future curricular development with respect to particle physics and suggests an increased inclusion of experimental particle physics concepts in high-school physics curricula.}, language = {en} } @inproceedings{Grum2024, author = {Grum, Marcus}, title = {Managing multi-site artificial neural networks' activation rates and activation cycles}, series = {Business modeling and software design : 14th International Symposium, BMSD 2024, Luxembourg City, Luxembourg, July 1-3, 2024, proceedings}, booktitle = {Business modeling and software design : 14th International Symposium, BMSD 2024, Luxembourg City, Luxembourg, July 1-3, 2024, proceedings}, editor = {Shishkov, Boris}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-64072-8}, doi = {10.1007/978-3-031-64073-5_17}, pages = {258 -- 269}, year = {2024}, abstract = {Traditionally, business models and software designs used to model the usage of artificial intelligence (AI) at a very specific point in the process or rather fix implemented application. Since applications can be based on AI, such as networked artificial neural networks (ANN) on top of which applications are installed, these on-top applications can be instructed directly from their underlying ANN compartments [1]. However, with the integration of several AI-based systems, their coordination is a highly relevant target factor for the operation and improvement of networked processes, such as they can be found in cross-organizational production contexts spanning multiple distributed locations. This work aims to extend prior research on managing artificial knowledge transfers among interlinked AIs as coordination instrument by examining effects of different activation types (respective activation rates and cycles) on by ANN-instructed production machines. In a design-science-oriented way, this paper conceptualizes rhythmic state descriptions for dynamic systems and associated 14 experiment designs. Two experiments have been realized, analyzed and evaluated thereafter in regard with their activities and processes induced. Findings show that the simulator [2] used and experiments designed and realized, here, (I) enable research on ANN activation types, (II) illustrate ANN-based production networks disrupted by activation types and clarify the need for harmonizing them. Further, (III) management interventions are derived for harmonizing interlinked ANNs. This study establishes the importance of site-specific coordination mechanisms and novel forms of management interventions as drivers of efficient artificial knowledge transfer.}, language = {en} } @article{ShlapunovTarchanov2022, author = {Shlapunov, Alexander A. and Tarchanov, Nikolaj Nikolaevič}, title = {Inverse image of precompact sets and regular solutions to the Navier-Stokes equations}, series = {Vestnik Udmurtskogo Universiteta. Matematika, mechanika, kompʹjuternye nauki}, volume = {32}, journal = {Vestnik Udmurtskogo Universiteta. Matematika, mechanika, kompʹjuternye nauki}, number = {2}, publisher = {Udmurtskij gosudarstvennyj universitet}, address = {Iževsk}, issn = {1994-9197}, doi = {10.35634/vm220208}, pages = {278 -- 297}, year = {2022}, abstract = {We consider the initial value problem for the Navier-Stokes equations over R-3 x [0, T] with time T > 0 in the spatially periodic setting. We prove that it induces open injective mappings A(s): B-1(s) -> B-2(s-1) where B-1(s), B-2(s-1) are elements from scales of specially constructed function spaces of Bochner-Sobolev typeparametrized with the smoothness index s is an element of N. Finally, we prove that a map Asis surjective if and only if the inverse image A(s)(- 1) (K) of any pre compact set K from the range of the map Asis bounded in the Bochner space L-s([0, T], L-r(T-3))with the Ladyzhenskaya-Prodi-Serrin numbers s, r.}, language = {en} } @inproceedings{Grum2024, author = {Grum, Marcus}, title = {Researching multi-site artificial neural networks' activation rates and activation cycles}, series = {Business modeling and software design : 14th International Symposium, BMSD 2024, Luxembourg City, Luxembourg, July 1-3, 2024, proceedings}, booktitle = {Business modeling and software design : 14th International Symposium, BMSD 2024, Luxembourg City, Luxembourg, July 1-3, 2024, proceedings}, editor = {Shishkov, Boris}, publisher = {Springer}, address = {Cham}, isbn = {978-3-031-64072-8}, doi = {10.1007/978-3-031-64073-5_12}, pages = {186 -- 206}, year = {2024}, abstract = {With the further development of more and more production machines into cyber-physical systems, and their greater integration with artificial intelligence (AI) techniques, the coordination of intelligent systems is a highly relevant target factor for the operation and improvement of networked processes, such as they can be found in cross-organizational production contexts spanning multiple distributed locations. This work aims to extend prior research on managing their artificial knowledge transfers as coordination instrument by examining effects of different activation types (respective activation rates and cycles) on by Artificial Neural Network (ANN)-instructed production machines. For this, it provides a new integration type of ANN-based cyber-physical production system as a tool to research artificial knowledge transfers: In a design-science-oriented way, a prototype of a simulation system is constructed as Open Source information system which will be used in on-building research to (I) enable research on ANN activation types in production networks, (II) illustrate ANN-based production networks disrupted by activation types and clarify the need for harmonizing them, and (III) demonstrate conceptual management interventions. This simulator shall establish the importance of site-specific coordination mechanisms and novel forms of management interventions as drivers of efficient artificial knowledge transfer.}, language = {en} } @article{SteinroetterSchauer2024, author = {Steinr{\"o}tter, Bj{\"o}rn and Schauer, Lina Marie}, title = {Lauterkeitsrechtliche Behandlung von Dark Patterns}, series = {Wettbewerb in Recht und Praxis}, volume = {38}, journal = {Wettbewerb in Recht und Praxis}, number = {8}, publisher = {Deutscher Fachverlag}, address = {Frankfurt am Main}, issn = {0172-049X}, pages = {873 -- 882}, year = {2024}, abstract = {Online-Nutzer begegnen regelm{\"a}ßig unterschwelligen manipulativen Designstrategien von Anbietern digitaler Produkte, welche sie zu rechtsgesch{\"a}ftlich relevanten Entscheidungen bewegen sollen, die sie wom{\"o}glich nicht - oder zumindest nicht so - beabsichtigt haben. Man spricht in diesem Zusammenhang von (vielgestaltig denkbaren) „Dark Patterns" (dt. „dunkle Muster"). Der Beitrag geht der Frage nach, inwiefern diese insbesondere lauterkeitsrechtlich zul{\"a}ssig sind.}, language = {de} } @article{LueckGuillemoteauTronickeetal.2022, author = {L{\"u}ck, Erika and Guillemoteau, Julien and Tronicke, Jens and Rummel, Udo and Hierold, Wilfried}, title = {From point to field scale-indirect monitoring of soil moisture variations at the DWD test site in Falkenberg}, series = {Geoderma : an international journal of soil science}, volume = {427}, journal = {Geoderma : an international journal of soil science}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0016-7061}, doi = {10.1016/j.geoderma.2022.116134}, pages = {15}, year = {2022}, abstract = {Information regarding the spatial distribution of soil water content is key in many disciplines and applications including soil and atmospheric sciences, hydrology, and agricultural engineering. Thus, within the past decades various experimental methods and strategies have been developed to map spatial variations in soil moisture distribution and to monitor temporal changes. Our study examines the combination of electrical resistivity mapping and point observations of soil moisture to infer the spatial and the temporal variability of soil moisture. Over a period of around two years, we performed field measurements on six days to collect repeated electrical resistivity mapping data for a nine-hectare test site south-east of Berlin, Germany. Permanently installed TDR probes, temporary TDR measurements within permanently installed tubes, and gravimetric measurements using soil samples provided soil moisture data at various selected points. In addition, soil analysis and classification results are available for 132 regularly distributed positions up to depths of 1.2 m. We compare and link three-dimensional resistivity models obtained via data inversion to soil composition and soil moisture as provided by our point data. Both the soil samples and the resistivity models indicate a two-layer medium characterized by a sandy top layer with varying thickness and a loamy bottom soil. For all six field campaigns, we observe similar resistivity patterns reflecting the temporally stable influence of soil texture. While the overall patterns are stable, the range of resistivity values changes with soil moisture. Finally, to estimate spatial models of soil moisture, we link our soil moisture and resistivity data using empirical petrophysical models relying on a second order polynomial function. We observe a mean prediction error for soil moisture of +/-0.034 m3 \& BULL; m? 3 using all observation points while we notice that point-specific models further reduce the error. Thus, we conclude that our experimental and data analysis strategies represent a reliable approach to establish site-specific models and to estimate three-dimensional moisture distribution including temporal variations.}, language = {en} } @article{SteinMukkavilliWagener2022, author = {Stein, Lina and Mukkavilli, Surya Karthik and Wagener, Thorsten}, title = {Lifelines for a drowning science - improving findability and synthesis of hydrologic publications}, series = {Hydrological processes}, volume = {36}, journal = {Hydrological processes}, number = {11}, publisher = {Wiley}, address = {New York, NY}, issn = {0885-6087}, doi = {10.1002/hyp.14742}, pages = {7}, year = {2022}, abstract = {Increasing publication numbers make it difficult to keep up with knowledge evolution in a science like hydrology. Here we give recommendations to authors and journals for writing future-proof articles that contribute to knowledge accumulation and synthesis.}, language = {en} } @incollection{Liese2024, author = {Liese, Andrea}, title = {Norm research on conflictive norm relations how norms collide in times of complexity, contestation, and crisis}, series = {Contesting the world}, booktitle = {Contesting the world}, editor = {Orchard, Phil and Wiener, Antje}, publisher = {Cambridge University Press}, address = {Cambridge}, isbn = {978-1-00-947917-2}, pages = {64 -- 84}, year = {2024}, language = {en} } @inproceedings{SchulzeDoeschnerGoegeretal.2022, author = {Schulze, Kora and D{\"o}schner, Larissa and G{\"o}ger, Lea and Franz, K. and M{\"u}ller-Werdan, Ursula and Norman, Kristina and Herpich, Catrin}, title = {Kurzeitige vegane Intervention senkt Inflammationsmarker}, series = {Zeitschrift f{\"u}r Gerontologie und Geriatrie}, volume = {55}, booktitle = {Zeitschrift f{\"u}r Gerontologie und Geriatrie}, number = {Suppl. 1}, publisher = {Springer Medizin}, address = {Heidelberg}, issn = {0948-6704}, doi = {10.1007/s00391-022-02095-7}, pages = {S83 -- S84}, year = {2022}, language = {de} } @article{PasechnikShmelevaSaidgazievetal.2022, author = {Pasechnik, Sergey V. and Shmeleva, Dina and Saidgaziev, Ayvr Sh. and Kharlamov, Semen and Vasilieva, Aleksandra A. and Santer, Svetlana}, title = {Shear flows induced by electro-osmotic pumps in optofluidic liquid crystal cell for modulation of visible light and THz irradiation}, series = {Liquid Crystals and their Application : Russian Journal}, volume = {22}, journal = {Liquid Crystals and their Application : Russian Journal}, number = {3}, publisher = {Nanomaterials Research Institute}, address = {Ivanovo}, issn = {1991-3966}, doi = {10.18083/LCAppl.2022.3.49}, pages = {49 -- 57}, year = {2022}, abstract = {The work is devoted to the use of electrokinetic phenomena in liquid crystals to create a new class of microfluidics devices - optofluidics, designed to control electromagnetic radiation, including the THz frequency range. To achieve the goal, an optical method is used to study changes in the orientational structure in LC layers caused by a shear flow generated by electroosmotic pumps. Simula-tion of LC behaviour in an experimental cell containing electroosmotic pumps and flat layers of a nematic liquid crystal is fulfilled. The experimental depend-ences of the intensity of polarized radiation passing through flat LC layers on the control voltage applied to the electroosmotic pump and the results of calcu-lations of the hydrodynamic and mechano-optical characteristics of the experi-mental LC cell are presented. The propagation of THz irradiation across the multilayer structure of the optofluidic cell is considered taking into account the minimum number of re-reflections of waves from different layers and the ab-sorption of THz irradiation in a propylene and a liquid crystal.}, language = {en} } @article{AbramovaGladkaya2024, author = {Abramova, Olga and Gladkaya, Margarita}, title = {Behind videoconferencing fatigue at work}, series = {Business \& information systems engineering}, journal = {Business \& information systems engineering}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, issn = {2363-7005}, doi = {10.1007/s12599-024-00874-7}, pages = {19}, year = {2024}, abstract = {A remarkable peculiarity of videoconferencing (VC) applications - the self-view - a.k.a. digital mirror, is examined as a potential reason behind the voiced exhaustion among users. This work draws on technostress research and objective self-awareness theory and proposes the communication role (sender vs. receiver) as an interaction variable. We report the results of two studies among European employees (n1 = 176, n2 = 253) with a one-year time lag. A higher frequency of self-view in a VC when receiving a message, i.e., listening to others, indirectly increases negative affect (study 1 \& 2) and exhaustion (study 2) via the increased state of public self-awareness. Self-viewing in the role of message sender, e.g., as an online presenter, also increases public self-awareness, but its overall effects are less harmful. As for individual differences, users predisposed to public self-consciousness were more concerned with how other VC participants perceived them. Gender effects were insignificant.}, language = {en} } @article{HuangHuangReichetal.2022, author = {Huang, Daniel Zhengyu and Huang, Jiaoyang and Reich, Sebastian and Stuart, Andrew M.}, title = {Efficient derivative-free Bayesian inference for large-scale inverse problems}, series = {Inverse problems : an international journal of inverse problems, inverse methods and computerised inversion of data}, volume = {38}, journal = {Inverse problems : an international journal of inverse problems, inverse methods and computerised inversion of data}, number = {12}, publisher = {IOP Publ. Ltd.}, address = {Bristol}, issn = {0266-5611}, doi = {10.1088/1361-6420/ac99fa}, pages = {40}, year = {2022}, abstract = {We consider Bayesian inference for large-scale inverse problems, where computational challenges arise from the need for repeated evaluations of an expensive forward model. This renders most Markov chain Monte Carlo approaches infeasible, since they typically require O(10(4)) model runs, or more. Moreover, the forward model is often given as a black box or is impractical to differentiate. Therefore derivative-free algorithms are highly desirable. We propose a framework, which is built on Kalman methodology, to efficiently perform Bayesian inference in such inverse problems. The basic method is based on an approximation of the filtering distribution of a novel mean-field dynamical system, into which the inverse problem is embedded as an observation operator. Theoretical properties are established for linear inverse problems, demonstrating that the desired Bayesian posterior is given by the steady state of the law of the filtering distribution of the mean-field dynamical system, and proving exponential convergence to it. This suggests that, for nonlinear problems which are close to Gaussian, sequentially computing this law provides the basis for efficient iterative methods to approximate the Bayesian posterior. Ensemble methods are applied to obtain interacting particle system approximations of the filtering distribution of the mean-field model; and practical strategies to further reduce the computational and memory cost of the methodology are presented, including low-rank approximation and a bi-fidelity approach. The effectiveness of the framework is demonstrated in several numerical experiments, including proof-of-concept linear/nonlinear examples and two large-scale applications: learning of permeability parameters in subsurface flow; and learning subgrid-scale parameters in a global climate model. Moreover, the stochastic ensemble Kalman filter and various ensemble square-root Kalman filters are all employed and are compared numerically. The results demonstrate that the proposed method, based on exponential convergence to the filtering distribution of a mean-field dynamical system, is competitive with pre-existing Kalman-based methods for inverse problems.}, language = {en} } @misc{RosenblumMcClintock2022, author = {Rosenblum, Michael and McClintock, Peter V. E.}, title = {In memoriam - Polina S. Landa (15 February 1931-21 October 2022)}, series = {Chaos : an interdisciplinary journal of nonlinear science}, volume = {32}, journal = {Chaos : an interdisciplinary journal of nonlinear science}, number = {12}, publisher = {American Institute of Physics}, address = {Woodbury, NY}, issn = {1054-1500}, doi = {10.1063/5.0136898}, pages = {2}, year = {2022}, language = {en} } @article{SandhageHofmannAngombeKindermannetal.2022, author = {Sandhage-Hofmann, Alexandra and Angombe, Simon and Kindermann, Liana and Linst{\"a}dter, Anja and M{\"o}rchen, Ramona}, title = {Conservation with elephants and agricultural intensification}, series = {Geoderma : an international journal of soil science}, volume = {425}, journal = {Geoderma : an international journal of soil science}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0016-7061}, doi = {10.1016/j.geoderma.2022.116009}, pages = {15}, year = {2022}, abstract = {Nature conservation is currently shaping many terrestrial ecosystems in Africa. This is particularly evident in Sub-Saharan Africa (SSA), where conservation is intended to recover wildlife populations, with special focus on elephants. Rising numbers of elephants induce woody biomass losses but increase soil organic carbon (SOC) stocks from decaying wood and dung. We hypothesized that these increases under wildlife conservation in SSA go along with rising contents of plant residues in SOC, traceable by the molecular markers lignin and n-alkanes. In contrast, agricultural intensification would reduce them due to lower C input and faster SOC turnover through tillage. To test this, we analyzed lignin by the CuO oxidation method and n-alkanes by fast pressurized solvent extraction in topsoils (0-10 cm) of Arenosols and corresponding plant samples (trees, grasses and crops). Sampling sites followed conservation gradients with low, medium and high elephant densities and intensification gradients with rangeland and cropland in the woodland savanna of the Namibian Zambezi Region. Patterns of lignin-derived phenols were retained in the soil, whereas n-alkanes showed shifts in chain lengths. n-Alkanes also showed no clear increase or decrease under conservation or intensification, respectively. Differently, lignin-derived phenols showed lower values under intensification than under conservation. Confirming our hypothesis, rising SOC contents with rising elephant densities (from 4.4 at low to 5.7 g kg(-1) SOC at high elephant densities) went along with an increasing accumulation of lignin-derived phenols (24.4-34.8 g kg(-1) VSCOC). This increase is associated with the input of woody debris to the soil, as indicated by V-units and carbon isotopes, modulated by clay and woody biomass. We conclude, that increasing input of woody residues into soil by browsing behaviour of elephants is an important mechanism for controlling SOC supply in the context of wildlife conservation and is traceable with lignin-derived phenols, but not with n-alkanes.}, language = {en} } @misc{Woywode2022, author = {Woywode, Felix}, title = {J{\"u}rgen Rathje (Hrsg.) 'Barthold Heinrich Brockes: Irdisches Vergn{\"u}gen in Gott. Siebenter und Achter Theil.' [Hrsg. und kommentiert v. J{\"u}rgen Rathje. Wallstein Verlag, G{\"o}ttingen 2021, 954 S.]}, series = {Zeitschrift f{\"u}r Germanistik}, volume = {32}, journal = {Zeitschrift f{\"u}r Germanistik}, number = {2}, publisher = {Lang}, address = {Bern ; Berlin ; Frankfurt, M. ; Wien}, issn = {0323-7982}, doi = {10.3726/92172_418}, pages = {430 -- 434}, year = {2022}, language = {de} } @article{ZhengToenjes2022, author = {Zheng, Chunming and T{\"o}njes, Ralf}, title = {Noise-induced swarming of active particles}, series = {Physical review : E, Statistical, nonlinear and soft matter physics}, volume = {106}, journal = {Physical review : E, Statistical, nonlinear and soft matter physics}, number = {6}, publisher = {American Physical Society}, address = {College Park}, issn = {2470-0045}, doi = {10.1103/PhysRevE.106.064601}, pages = {7}, year = {2022}, abstract = {We report on the effect of spatially correlated noise on the velocities of self-propelled particles. Correlations in the random forces acting on self-propelled particles can induce directed collective motion, i.e., swarming. Even with repulsive coupling in the velocity directions, which favors a disordered state, strong correlations in the fluctuations can align the velocities locally leading to a macroscopic, turbulent velocity field. On the other hand, while spatially correlated noise is aligning the velocities locally, the swarming transition to globally directed motion is inhibited when the correlation length of the noise is nonzero, but smaller than the system size. We analyze the swarming transition in d-dimensional space in a mean field model of globally coupled velocity vectors.}, language = {en} } @misc{GenazzanoMompo2022, author = {Genazzano Mompo, Pablo Adrian}, title = {Elettra Stimilli 'Jacob Taubes: Soberan{\´i}a y tiempo mesi{\´a}nico'. [Trad. Martino Sacchi. Revisi{\´o}n de Francisco Caja y Volker Herrmann. Barcelona: Los Libros del T{\´a}bano, 2020, 360 p., ISBN: 9788409263097]}, series = {Convivium - Revista de Filosofia}, journal = {Convivium - Revista de Filosofia}, number = {35}, publisher = {Universitat de Barcelona}, address = {Barcelona}, issn = {0010-8235}, pages = {245 -- 249}, year = {2022}, language = {es} } @article{WenderingNikoloski2022, author = {Wendering, Philipp and Nikoloski, Zoran}, title = {Genome-scale modeling specifies the metabolic capabilities of Rhizophagus irregularis}, series = {mSystems}, volume = {7}, journal = {mSystems}, number = {1}, publisher = {American Society for Microbiology}, address = {Washington, DC}, issn = {2379-5077}, doi = {10.1128/msystems.01216-21}, pages = {17}, year = {2022}, abstract = {Rhizophagus irregularis is one of the most extensively studied arbuscular mycorrhizal fungi (AMF) that forms symbioses with and improves the performance of many crops. Lack of transformation protocol for R. irregularis renders it challenging to investigate molecular mechanisms that shape the physiology and interactions of this AMF with plants. Here, we used all published genomics, transcriptomics, and metabolomics resources to gain insights into the metabolic functionalities of R. irregularis by reconstructing its high-quality genome-scale metabolic network that considers enzyme constraints. Extensive validation tests with the enzyme-constrained metabolic model demonstrated that it can be used to (i) accurately predict increased growth of R. irregularis on myristate with minimal medium; (ii) integrate enzyme abundances and carbon source concentrations that yield growth predictions with high and significant Spearman correlation (rS = 0.74) to measured hyphal dry weight; and (iii) simulate growth rate increases with tighter association of this AMF with the host plant across three fungal structures. Based on the validated model and system-level analyses that integrate data from transcriptomics studies, we predicted that differences in flux distributions between intraradical mycelium and arbuscles are linked to changes in amino acid and cofactor biosynthesis. Therefore, our results demonstrated that the enzyme-constrained metabolic model can be employed to pinpoint mechanisms driving developmental and physiological responses of R. irregularis to different environmental cues. In conclusion, this model can serve as a template for other AMF and paves the way to identify metabolic engineering strategies to modulate fungal metabolic traits that directly affect plant performance. IMPORTANCE Mounting evidence points to the benefits of the symbiotic interactions between the arbuscular mycorrhiza fungus Rhizophagus irregularis and crops; however, the molecular mechanisms underlying the physiological responses of this fungus to different host plants and environments remain largely unknown. We present a manually curated, enzyme-constrained, genome-scale metabolic model of R. irregularis that can accurately predict experimentally observed phenotypes. We show that this high-quality model provides an entry point into better understanding the metabolic and physiological responses of this fungus to changing environments due to the availability of different nutrients. The model can be used to design metabolic engineering strategies to tailor R. irregularis metabolism toward improving the performance of host plants.}, language = {en} } @inproceedings{FayyazHartmannHanacketal.2022, author = {Fayyaz, Susann and Hartmann, Bolette and Hanack, Katja and Michelchen, Sophia and Kreiling, Reinhard}, title = {Development of a hematopoietic stem cell (murine system) based system as an alternative for the in vivo T-cell-dependent antibody response (TDAR) assay within the EOGRTS: case-study with Parabens}, series = {Toxicology letters}, volume = {368}, booktitle = {Toxicology letters}, publisher = {Elsevier Science}, address = {Amsterdam [u.a.]}, issn = {0378-4274}, doi = {10.1016/j.toxlet.2022.07.483}, pages = {S175 -- S176}, year = {2022}, language = {en} } @article{AngerChristophGalkiewiczetal.2024, author = {Anger, Silke and Christoph, Bernhard and Galkiewicz, Agata and Margaryan, Shushanik and Peter, Frauke and Sandner, Malte and Siedler, Thomas}, title = {War, international spillovers, and adolescents}, series = {Journal of Economic Behavior \& Organization}, volume = {224}, journal = {Journal of Economic Behavior \& Organization}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0167-2681}, doi = {10.1016/j.jebo.2024.03.009}, pages = {181 -- 193}, year = {2024}, abstract = {Using novel longitudinal data, this paper studies the short- and medium-term effects of Russia's invasion of Ukraine on February 24, 2022 on social trust of adolescents in Germany. Comparing adolescents who responded to our survey shortly before the start of the war with those who responded shortly after the conflict began and applying difference-in-differences (DiD) models over time, we find a significant decline in the outcome after the war started. These findings provide new evidence on how armed conflicts influence social trust and well-being among young people in a country not directly involved in the war.}, language = {en} } @phdthesis{Schauer2024, author = {Schauer, Lina Marie}, title = {Reputation auf Online-Plattformen}, series = {Datenrecht und neue Technologien}, volume = {10}, journal = {Datenrecht und neue Technologien}, edition = {1}, publisher = {Nomos}, address = {Baden-Baden}, isbn = {978-3-7560-1720-1}, issn = {2749-7534}, doi = {10.5771/9783748944492}, pages = {384}, year = {2024}, abstract = {Wie ist der „gute Ruf" von Unternehmen und Einzelpersonen im Umfeld von Online-Bewertungsplattformen gesch{\"u}tzt? Das Werk erforscht, ob und inwieweit das geltende Recht einen ad{\"a}quaten und l{\"u}ckenlosen Schutz f{\"u}r die unternehmerische und personelle Reputation gew{\"a}hrleitstet. Die Systematisierung und Untersuchung des bestehenden Regelungsgef{\"u}ges konzentriert sich auf das Lauterkeitsrecht und das allgemeine Deliktsrecht unter besonderer Ber{\"u}cksichtigung der rechtlichen Innovationen auf nationaler (UWG-Reform 2022) und europ{\"a}ischer (New Deal for Consumers, Digital Services Act) Ebene. Die Dissertation wurde f{\"u}r den ›Justizpreis Berlin-Brandenburg - Carl Gottlieb Svarez 2024‹ vorgeschlagen.}, language = {de} } @misc{GolleScheiterHasselhorn2022, author = {Golle, Jessika and Scheiter, Katharina and Hasselhorn, Marcus}, title = {Editorial: Leistungsstarke und besonders Begabte}, series = {Zeitschrift f{\"u}r Erziehungswissenschaft}, volume = {25}, journal = {Zeitschrift f{\"u}r Erziehungswissenschaft}, number = {5}, publisher = {Springer}, address = {Berlin; Heidelberg}, issn = {1434-663X}, doi = {10.1007/s11618-022-01131-x}, pages = {1059 -- 1062}, year = {2022}, language = {de} } @article{RiehlSchroeder2022, author = {Riehl, Claudia Maria and Schroeder, Christoph}, title = {DaF / DaZ im Kontext von Mehrsprachigkeit}, series = {Deutsch als Fremdsprache : Zeitschrift zur Theorie und Praxis des Faches Deutsch als Fremdsprache}, volume = {59}, journal = {Deutsch als Fremdsprache : Zeitschrift zur Theorie und Praxis des Faches Deutsch als Fremdsprache}, number = {2}, publisher = {Erich Schmidt Verlag}, address = {Berlin}, issn = {0011-9741}, doi = {10.37307/j.2198-2430.2022.02}, pages = {67 -- 76}, year = {2022}, abstract = {Der Beitrag beleuchtet die Perspektiven von DaF und DaZ im Kontext von Mehrsprachigkeit. Zun{\"a}chst wird ein Verst{\"a}ndnis von ‚Mehrsprachigkeitʻ erarbeitet und diskutiert. Anschließend wird gezeigt, wie sich DaZ, DaF und die Forschung zu Variet{\"a}ten des Deutschen im Ausland im Rahmen dieses Verst{\"a}ndnisses von Mehrsprachigkeit positionieren lassen. Der Beitrag schließt mit einem Pl{\"a}doyer f{\"u}r ein neues, integratives Konzept von ‚Deutsch im Mehrsprachigkeitskontextʻ.}, language = {de} } @techreport{SchauerMarkert2023, author = {Schauer, Lina Marie and Markert, Jette}, title = {8. Tagung GRUR Junge Wissenschaft - Kolloquium zum Gewerblichen Rechtsschutz, Urheber- und Medienrecht vom 23. und 24.6.2023 an der Universit{\"a}t Potsdam}, series = {Newsdienst MMR-Aktuell : der Newsletter zur Zeitschrift Multimedia und Recht}, journal = {Newsdienst MMR-Aktuell : der Newsletter zur Zeitschrift Multimedia und Recht}, number = {18}, publisher = {C.H. Beck}, address = {M{\"u}nchen}, pages = {14}, year = {2023}, abstract = {Am 23. und 24. Juni 2023 fand die 8. Tagung der „GRUR Junge Wissenschaft - Kolloquium zum Gewerblichen Rechtsschutz, Urheber- und Medienrecht" zum Thema „Plattformen - Grundlagen und Neuordnung des Rechts digitaler Plattformen" in Potsdam statt. Die Organisatorinnen und Organisatoren, Prof. Dr. Johannes Buchheim (Phillips-Universit{\"a}t Marburg), Dr. Victoria Kraetzig (Goethe-Universit{\"a}t Frankfurt/M.), Prof. Dr. Juliane Mendelsohn (Technische Universit{\"a}t Ilmenau) und Prof. Dr. Bj{\"o}rn Steinr{\"o}tter (Universit{\"a}t Potsdam) begr{\"u}ßten die rund 120 Teilnehmerinnen und Teilnehmer in den R{\"a}umlichkeiten der Universit{\"a}t Potsdam am Campus Griebnitzsee.}, language = {de} } @article{RinkerBloderPloetner2022, author = {Rinker, Tanja and Bloder, Theresa Sophie and Pl{\"o}tner, Kathleen}, title = {Italian and German lexical development in Italian heritage speakers in kindergarten and elementary school settings}, series = {Lingue e linguaggio / Dipartimento di Lingue}, volume = {21}, journal = {Lingue e linguaggio / Dipartimento di Lingue}, number = {1}, publisher = {Societ{\`a} editrice il Mulino}, address = {Bologna}, issn = {1720-9331}, doi = {10.1418/104449}, pages = {53 -- 72}, year = {2022}, abstract = {Language development in children with a heritage language background is often characterized by a shift towards the majority language once children enter formal educational contexts. In Germany, educational programs that target heritage languages are scarce. It is therefore of interest whether children with a heritage language background can benefit from a bilingual program targeting their heritage language. In this paper, we report data on the lexical skills of Italian heritage children in two educational contexts, bilingual Italian-German kindergartens and a bilingual Italian-German elementary school. We examine (1) developmental trajectories of children's lexical skills in German and Italian, (2) differences between noun and verb development, (3) differences between lexical production and comprehenand Italian, kindergarteners showed balanced receptive vocabulary skills. By contrast, elementary school-children had a larger German than Italian vocabulary. Both groups demonstrated a clear dominance of nouns over verbs. While school children already performed at ceiling in German at the end of first grade, across the school years, their Italian vocabulary increased, nouns in particular.}, language = {en} } @article{SteinroetterMarkert2022, author = {Steinr{\"o}tter, Bj{\"o}rn and Markert, Jette}, title = {Lokalisierung des Erfolgsorts bei Verm{\"o}gensdelikten („Vereniging van Effectenbezitters/BP plc")}, series = {Juris-PraxisReport}, journal = {Juris-PraxisReport}, number = {1}, publisher = {Juris GmbH}, address = {Saarbr{\"u}cken}, issn = {2364-4702}, pages = {4}, year = {2022}, language = {de} } @article{Krueger2022, author = {Kr{\"u}ger, Hans-Peter}, title = {Critical anthropology? On the relation between philosophical anthropology and critical theory}, series = {Iride : filosofia e discussione pubblica}, volume = {35}, journal = {Iride : filosofia e discussione pubblica}, number = {2}, publisher = {Societ{\`a} editrice il Mulino}, address = {Bologna}, isbn = {978-88-15-38060-9}, issn = {1122-7893}, doi = {10.1414/106105}, pages = {313 -- 331}, year = {2022}, abstract = {This article compares Max Horkheimer's and Theodor W. Adorno's foundation of the Frankfurt Critical Theory with Helmuth Plessner's foundation of Philosophical Anthropology. While Horkheimer's and Plessner's paradigms are mutually incompatible, Adorno's << negative dialectics >> and Plessner's << negative anthropology >> (G. Gamm) can be seen as complementing one another. Jurgen Habermas at one point sketched a complementary relationship between his own publicly communicative theory of modern society and Plessner's philosophy of nature and human expressivity, and though he then came to doubt this, he later reaffirmed it. Faced with the << life power >> in << high capitalism >> (Plessner), the ambitions for a public democracy in a pluralistic society have to be broadened from an argumentative focus (Habermas) to include the human condition and the expressive modes of our experience as essentially embodied persons. The article discusses some possible aspects of this complementarity under the title of a << critical anthropology >> (H. Schn{\"a}delbach).}, language = {en} } @incollection{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Der Versuch der Mitt{\"a}terin im Lichte des Urteils gegen Beate Zsch{\"a}pe}, series = {Strafrecht und Strafverteidigung in Geschichte, Praxis und Politik : Festschrift f{\"u}r Alexander Ignor zum 70. Geburtstag}, booktitle = {Strafrecht und Strafverteidigung in Geschichte, Praxis und Politik : Festschrift f{\"u}r Alexander Ignor zum 70. Geburtstag}, editor = {Bertheau, Camilla and Beulke, Werner and Jahn, Matthias and M{\"u}ller-Jacobsen, Anke and Schmitt-Leonardy, Charlotte}, publisher = {C.F. M{\"u}ller}, address = {Heidelberg}, isbn = {978-3-8114-5449-1}, pages = {313 -- 328}, year = {2023}, language = {de} } @incollection{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Lebensmittelerpresser und dolus alternativus}, series = {Liberalit{\"a}t und Verantwortung : Festschrift f{\"u}r Jan C. Joerden zum 70. Geburtstag}, booktitle = {Liberalit{\"a}t und Verantwortung : Festschrift f{\"u}r Jan C. Joerden zum 70. Geburtstag}, editor = {Hilgendorf, Eric and Hochmayr, Gudrun and Małolepszy, Maciej and Długosz-J{\´o}{\'{z}}wiak, Joanna}, publisher = {Duncker \& Humblot}, address = {Berlin}, isbn = {978-3-428-18423-1}, doi = {10.3790/978-3-428-58423-9}, pages = {433 -- 447}, year = {2023}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Warum \S 362 Nr. 5 StPO aufgehoben werden sollte}, series = {KriPoZ : kriminalpolitische Zeitschrift}, volume = {8}, journal = {KriPoZ : kriminalpolitische Zeitschrift}, number = {5}, publisher = {Universit{\"a}t zu K{\"o}ln}, address = {K{\"o}ln}, issn = {2509-6826}, pages = {371 -- 378}, year = {2023}, abstract = {Mit Spannung wird die Entscheidung des BVerfG zu \S 362 Nr. 5 StPO erwartet. Die Verfassungsbeschwerde des Beschuldigten, der vor Jahrzehnten vom Vorwurf des Mordes rechtskr{\"a}ftig freigesprochen worden war und der nun bef{\"u}rchten muss, auf der Grundlage des \S 362 Nr. 5 StPO wegen derselben Tat verurteilt zu werden, hat die verfassungsrechtliche {\"U}berpr{\"u}fung der Vorschrift veranlasst. Zuvor waren bereits in zahlreichen Texten von Rechtswissenschaftlern Argumente f{\"u}r und gegen die Regelung ausgetauscht worden. Verst{\"a}ndlicherweise steht dabei Art. 103 Abs. 3 GG im Vordergrund. Wer \S 362 Nr. 5 StPO ablehnt, begr{\"u}ndet das in erster Linie mit einer Verletzung des ne-bis-in-idem-Grundsatzes. Nicht wenige Bef{\"u}rworter der erweiterten Wiederaufnahmem{\"o}glichkeit verweisen - gef{\"u}hlsgeleitet - auf „materielle Gerechtigkeit" sowie auf „schlechterdings unertr{\"a}gliche Ergebnisse". Unbefriedigend ist das f{\"u}r Menschen, die es weder ungerecht noch unertr{\"a}glich finden, dass ein Tatverd{\"a}chtiger nach rechtskr{\"a}ftigem Freispruch bis an sein Lebensende als „unschuldig" gilt und zwar auch, wenn auf Grund neuer Beweismittel aus dem Freigesprochenen ein zu lebenslanger Freiheitsstrafe Verurteilter werden k{\"o}nnte. Dass das Festhalten am rechtskr{\"a}ftigen Freispruch richtig ist, daf{\"u}r gibt es starke juristische Gr{\"u}nde. Auch f{\"u}r die Durchbrechung des Strafklageverbrauchs in den von \S 362 Nr. 5 StPO erfassten F{\"a}llen gibt es gewiss beachtliche Gr{\"u}nde. Sie sind meines Erachtens jedoch nicht gewichtig genug. Im vorliegenden Text soll die verfassungsrechtliche Dimension außen vor bleiben. Eine neue Vorschrift, mit der das geltende Strafprozessrecht ver{\"a}ndert wird, muss auch eine Pr{\"u}fung am Maßstab des geltenden Strafprozessrechts durchlaufen, um akzeptiert werden zu k{\"o}nnen. \S 362 Nr. 5 StPO f{\"a}llt bei dieser Pr{\"u}fung durch und sollte deshalb aufgehoben werden.}, language = {de} } @article{Mitsch2024, author = {Mitsch, Wolfgang}, title = {Entkriminalisierung des unerlaubten Entfernens vom Unfallort}, series = {Deutsches Autorecht}, volume = {94}, journal = {Deutsches Autorecht}, number = {1}, publisher = {Juristische Zentrale des ADAC e.V.}, address = {M{\"u}nchen}, issn = {0012-1231}, pages = {15 -- 19}, year = {2024}, abstract = {Der Ruf nach gesetzgeberischen Reparaturmaßnahmen am unbestrittenermaßen missgl{\"u}ckten \S STGB \S 142 StGB ist ein kriminalpolitischer Dauerbrenner. Neu sind recht konkrete Vorschl{\"a}ge aus dem Bundesministerium der Justiz zu einer Reduktion des objektiven Tatbestandes, durch die ein betr{\"a}chtlicher Anteil der Anwendungsf{\"a}lle k{\"u}nftig in das Ordnungswidrigkeitenrecht verlagert werden soll. Unf{\"a}lle, die „reine Sachsch{\"a}den" verursachen, sollen eine nur noch bußgeldbewehrte Warte- und Feststellungserm{\"o}glichungspflicht ausl{\"o}sen. Die im Vorstadium eines Gesetzesentwurfs publizierten ministeriellen Ideen haben ein geteiltes Echo - Zustimmung und Ablehnung - ausgel{\"o}st. Der Beitrag befasst sich nicht mit der umstrittenen kriminalpolitischen Vern{\"u}nftigkeit der Pl{\"a}ne, zeigt aber einige strafrechtsdogmatische Aspekte auf, die bei der Neufassung des Gesetzeswortlauts zu beachten sein werden.}, language = {de} } @article{Mitsch2024, author = {Mitsch, Wolfgang}, title = {Fortschritte im Notwehrrecht?}, series = {KriPoZ : kriminalpolitische Zeitschrift}, volume = {9}, journal = {KriPoZ : kriminalpolitische Zeitschrift}, number = {3}, publisher = {Universit{\"a}t zu K{\"o}ln}, address = {K{\"o}ln}, issn = {2509-6826}, pages = {148 -- 156}, year = {2024}, abstract = {Der untenstehende Text ist eine recht spontane Reaktion auf Bemerkungen, die j{\"u}ngst von den Kollegen Armin Engl{\"a}nder und Christian R{\"u}ckert zu einem Kodifizierungsvorschlag f{\"u}r die Regelungsthemen Notwehr, Notwehrexzess und subjektives Rechtfertigungselement in der Zeitschrift „Goltdammer's Archiv f{\"u}r Strafrecht" pr{\"a}sentiert wurden. Den Entwurfstext hat eine - kleine - Gruppe von Strafrechtslehrern erarbeitet. Er wurde letztes Jahr mittels eines Aufsatzes von Elisa Hoven und Wolfgang Mitsch - ebenfalls im „Goltdammer's Archiv" - vorgestellt und erl{\"a}utert. Engl{\"a}nder und R{\"u}ckert {\"a}ußern stellenweise Zustimmung, {\"u}ben aber auch zu vielen Punkten des Entwurfs und seiner Begr{\"u}ndung Kritik. Da der hiesige Verfasser sowohl an der Entwicklung des Entwurfstextes als auch an dem genannten GA-Aufsatz als Ko-Autor beteiligt war, m{\"o}chte er - im Folgenden: ich - zu einigen der Kritiken Stellung nehmen.}, language = {de} } @phdthesis{Mayer2024, author = {Mayer, Selina}, title = {Understanding the impact of design thinking on organizations and individuals}, doi = {10.25932/publishup-65154}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-651541}, school = {Universit{\"a}t Potsdam}, pages = {xi, 125}, year = {2024}, abstract = {Organizations are investing billions on innovation and agility initiatives to stay competitive in their increasingly uncertain business environments. Design Thinking, an innovation approach based on human-centered exploration, ideation and experimentation, has gained increasing popularity. The market for Design Thinking, including software products and general services, is projected to reach 2.500 million \$ (US-Dollar) by 2028. A dispersed set of positive outcomes have been attributed to Design Thinking. However, there is no clear understanding of what exactly comprises the impact of Design Thinking and how it is created. To support a billion-dollar market, it is essential to understand the value Design Thinking is bringing to organizations not only to justify large investments, but to continuously improve the approach and its application. Following a qualitative research approach combined with results from a systematic literature review, the results presented in this dissertation offer a structured understanding of Design Thinking impact. The results are structured along two main perspectives of impact: the individual and the organizational perspective. First, insights from qualitative data analysis demonstrate that measuring and assessing the impact of Design Thinking is currently one central challenge for Design Thinking practitioners in organizations. Second, the interview data revealed several effects Design Thinking has on individuals, demonstrating how Design Thinking can impact boundary management behaviors and enable employees to craft their jobs more actively. Contributing to innovation management research, the work presented in this dissertation systematically explains the Design Thinking impact, allowing other researchers to both locate and integrate their work better. The results of this research advance the theoretical rigor of Design Thinking impact research, offering multiple theoretical underpinnings explaining the variety of Design Thinking impact. Furthermore, this dissertation contains three specific propositions on how Design Thinking creates an impact: Design Thinking creates an impact through integration, enablement, and engagement. Integration refers to how Design Thinking enables organizations through effectively combining things, such as for example fostering balance between exploitation and exploration activities. Through Engagement, Design Thinking impacts organizations involving users and other relevant stakeholders in their work. Moreover, Design Thinking creates impact through Enablement, making it possible for individuals to enact a specific behavior or experience certain states. By synthesizing multiple theoretical streams into these three overarching themes, the results of this research can help bridge disciplinary boundaries, for example between business, psychology and design, and enhance future collaborative research. Practitioners benefit from the results as multiple desirable outcomes are detailed in this thesis, such as successful individual job crafting behaviors, which can be expected from practicing Design Thinking. This allows practitioners to enact more evidence-based decision-making concerning Design Thinking implementation. Overall, considering multiple levels of impact as well as a broad range of theoretical underpinnings are paramount to understanding and fostering Design Thinking impact.}, language = {en} } @article{Mitsch2024, author = {Mitsch, Wolfgang}, title = {Strafbare Verabredung zu verbotenen Kraftfahrzeugrennen}, series = {Neue Zeitschrift f{\"u}r Verkehrsrecht}, volume = {36}, journal = {Neue Zeitschrift f{\"u}r Verkehrsrecht}, number = {8}, publisher = {C.H. Beck}, address = {M{\"u}nchen}, issn = {0934-1307}, pages = {373 -- 377}, year = {2024}, abstract = {Illegales Wettrasen auf {\"o}ffentlichen Straßen besch{\"a}ftigt Staatsanwaltschaften und Strafgerichte, wenn dieses Ereignis stattgefunden und oftmals auch schwere Sch{\"a}den verursacht hat. Jeder hat noch das Verfahren um das t{\"o}dliche Geschehen auf der Berliner Tauentzienstrasse im Ged{\"a}chtnis und vor Augen. Naturgem{\"a}ß geht einer solchen Aktion stets eine - wenn auch nur kurze und evtl. nonverbale (z. B. Kopfnicken, Handzeichen) - Verst{\"a}ndigung der Teilnehmer voraus. Praktisch mag die Frage keine Bedeutung haben, theoretisch interessant ist sie aber schon: Ist bereits diese Kommunikation in der Anbahnungsphase m{\"o}glicherweise strafbares Verhalten? Praktisch w{\"u}rde sich die M{\"o}glichkeit der Strafverfolgung darauf beschr{\"a}nken, wenn aus irgendeinem Grund das Rennen dann doch nicht stattgefunden hat. Daher sollen hier - weil das nach meiner Beobachtung noch nirgends geschehen ist - zu diesem Thema ein paar kl{\"a}rende Ausf{\"u}hrungen gemacht werden.}, language = {de} } @book{MitschEllbogen2024, author = {Mitsch, Wolfgang and Ellbogen, Klaus}, title = {F{\"a}lle zum Strafprozessrecht}, series = {Klausurenkurs Juristische {\"U}bungsb{\"u}cher}, journal = {Klausurenkurs Juristische {\"U}bungsb{\"u}cher}, edition = {3. neu bearbeitete Auflage}, publisher = {Verlag Franz Vahlen}, address = {M{\"u}nchen}, isbn = {978-3-8006-7003-1}, pages = {XVI, 212}, year = {2024}, abstract = {Das Werk bietet eine umfassende Fallsammlung zum Strafprozessrecht. Dabei werden jeder Falll{\"o}sung eine umfassende gutachterliche Vor{\"u}berlegung sowie eine L{\"o}sungsgliederung vorangestellt. Die eigentliche ausf{\"u}hrliche L{\"o}sung enth{\"a}lt zus{\"a}tzlich Klausurtipps und Vertiefungshinweise.}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Zum Tatbestand des Anbaus von Bet{\"a}ubungsmitteln}, series = {Juristische Rundschau}, journal = {Juristische Rundschau}, number = {5}, publisher = {De Gruyter}, address = {Berlin}, issn = {0022-6920}, doi = {10.1515/juru-2023-2113}, pages = {256 -- 260}, year = {2023}, abstract = {BtMG \S 30 a Abs. 1 Der Anbau von Bet{\"a}ubungsmitteln in Form der Aufzucht umfasst s{\"a}mtliche g{\"a}rtnerischen oder landwirtschaftlichen Bem{\"u}hungen, um Wachstum von in den Anlagen I bis III zum Bet{\"a}ubungsmittelgesetz genannten Pflanzen zu erreichen. Hierzu z{\"a}hlen namentlich das Bew{\"a}ssern, das D{\"u}ngen und das Belichten BGH, Urteil vom 6. September 2023 - 6 StR 107/23}, language = {de} } @article{ChemuraSchrumpfGuenteretal.2023, author = {Chemura, Sitshengisiwe and Schrumpf, Tim and G{\"u}nter, Christina and Kumke, Michael Uwe}, title = {Ceria nanomaterials containing ytterbium}, series = {RSC Advances : an international journal to further the chemical sciences}, volume = {13}, journal = {RSC Advances : an international journal to further the chemical sciences}, number = {50}, publisher = {RSC Publishing}, address = {London}, issn = {2046-2069}, doi = {10.1039/D3RA06868D}, pages = {35445 -- 35456}, year = {2023}, abstract = {Lanthanide based ceria nanomaterials are important practical materials due to the redox properties that are useful in the avenues pertaining to technology and life sciences. Sub 10 nm spherical and highly monodisperse Ce1-xYbxO2-y (0.04 ≤ x ≤ 0.22) nanoparticles were synthesized by thermal decomposition, annealed separately at 773 K and 1273 K for 2 hours and characterized. Elemental mapping for Yb3+ doped ceria nanoparticles shows homogeneous distribution of Yb3+ atoms in the ceria with low Yb3+ content annealed at 773 K and 1273 K for 2 hours. However, clusters are observed for 773 K annealed ceria samples with high concentration of Yb3+. These clusters are not detected in 1273 K annealed nanomaterials. Introducing small amounts of Yb3+ ions into the ceria lattice as spectroscopic probes can provide detailed information about the atomic structure and local environments allowing the monitoring of small structural changes, such as clustering. The emission spectra observed at room temperature and at 4 K have a manifold of bands that corresponds to the 2F5/2 → 2F7/2 transition of Yb3+ ions. Some small shifts are observed in the Stark splitting pattern depending on the sample and the annealing conditions. The deconvolution by PARAFAC analysis yielded luminescence decay kinetics as well as the associated luminescence spectra of three species for each of the low Yb3+ doped ceria samples annealed at 773 K and one species for the 1273 K annealed samples. However, the ceria samples with high concentration of Yb3+ annealed at the two temperatures showed only one species with lower decay times as compared to the low Yb3+ doped ceria samples.}, language = {en} } @phdthesis{Heckenbach2024, author = {Heckenbach, Esther Lina}, title = {Geodynamic modeling of process interactions at continental plate boundaries}, doi = {10.25932/publishup-64750}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-647500}, school = {Universit{\"a}t Potsdam}, pages = {127}, year = {2024}, abstract = {Plate tectonic boundaries constitute the suture zones between tectonic plates. They are shaped by a variety of distinct and interrelated processes and play a key role in geohazards and georesource formation. Many of these processes have been previously studied, while many others remain unaddressed or undiscovered. In this work, the geodynamic numerical modeling software ASPECT is applied to shed light on further process interactions at continental plate boundaries. In contrast to natural data, geodynamic modeling has the advantage that processes can be directly quantified and that all parameters can be analyzed over the entire evolution of a structure. Furthermore, processes and interactions can be singled out from complex settings because the modeler has full control over all of the parameters involved. To account for the simplifying character of models in general, I have chosen to study generic geological settings with a focus on the processes and interactions rather than precisely reconstructing a specific region of the Earth. In Chapter 2, 2D models of continental rifts with different crustal thicknesses between 20 and 50 km and extension velocities in the range of 0.5-10 mm/yr are used to obtain a speed limit for the thermal steady-state assumption, commonly employed to address the temperature fields of continental rifts worldwide. Because the tectonic deformation from ongoing rifting outpaces heat conduction, the temperature field is not in equilibrium, but is characterized by a transient, tectonically-induced heat flow signal. As a result, I find that isotherm depths of the geodynamic evolution models are shallower than a temperature distribution in equilibrium would suggest. This is particularly important for deep isotherms and narrow rifts. In narrow rifts, the magnitude of the transient temperature signal limits a well-founded applicability of the thermal steady-state assumption to extension velocities of 0.5-2 mm/yr. Estimation of the crustal temperature field affects conclusions on all temperature-dependent processes ranging from mineral assemblages to the feasible exploitation of a geothermal reservoir. In Chapter 3, I model the interactions of different rheologies with the kinematics of folding and faulting using the example of fault-propagation folds in the Andean fold-and-thrust belt. The evolution of the velocity fields from geodynamic models are compared with those from trishear models of the same structure. While the latter use only geometric and kinematic constraints of the main fault, the geodynamic models capture viscous, plastic, and elastic deformation in the entire model domain. I find that both models work equally well for early, and thus relatively simple stages of folding and faulting, while results differ for more complex situations where off-fault deformation and secondary faulting are present. As fault-propagation folds can play an important role in the formation of reservoirs, knowledge of fluid pathways, for example via fractures and faults, is crucial for their characterization. Chapter 4 deals with a bending transform fault and the interconnections between tectonics and surface processes. In particular, the tectonic evolution of the Dead Sea Fault is addressed where a releasing bend forms the Dead Sea pull-apart basin, while a restraining bend further to the North resulted in the formation of the Lebanese mountains. I ran 3D coupled geodynamic and surface evolution models that included both types of bends in a single setup. I tested various randomized initial strain distributions, showing that basin asymmetry is a consequence of strain localization. Furthermore, by varying the surface process efficiency, I find that the deposition of sediment in the pull-apart basin not only controls basin depth, but also results in a crustal flow component that increases uplift at the restraining bend. Finally, in Chapter 5, I present the computational basis for adding further complexity to plate boundary models in ASPECT with the implementation of earthquake-like behavior using the rate-and-state friction framework. Despite earthquakes happening on a relatively small time scale, there are many interactions between the seismic cycle and the long time spans of other geodynamic processes. Amongst others, the crustal state of stress as well as the presence of fluids or changes in temperature may alter the frictional behavior of a fault segment. My work provides the basis for a realistic setup of involved structures and processes, which is therefore important to obtain a meaningful estimate for earthquake hazards. While these findings improve our understanding of continental plate boundaries, further development of geodynamic software may help to reveal even more processes and interactions in the future.}, language = {en} } @misc{Mitsch2024, author = {Mitsch, Wolfgang}, title = {Fischer Strafgesetzbuch}, series = {Neue juristische Wochenschrift}, volume = {76}, journal = {Neue juristische Wochenschrift}, number = {10}, publisher = {C.H. Beck}, address = {M{\"u}nchen}, issn = {0341-1915}, pages = {639 -- 640}, year = {2024}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Zu zweit alkoholisiert auf einem E-Scooter}, series = {Neue Zeitschrift f{\"u}r Verkehrsrecht}, volume = {36}, journal = {Neue Zeitschrift f{\"u}r Verkehrsrecht}, number = {5}, publisher = {C.H. Beck}, address = {M{\"u}nchen}, issn = {0934-1307}, pages = {197 -- 202}, year = {2023}, abstract = {Entscheidungen {\"u}ber die vorl{\"a}ufige Entziehung der Fahrerlaubnis nach \S STPO \S 111 a StPO r{\"u}cken in der Regel nicht in das Licht der {\"O}ffentlichkeit. Sie m{\"u}ssen schon aus tats{\"a}chlichen oder rechtlichen Gr{\"u}nden eine Besonderheit darstellen, um {\"u}ber die Medien einem breiteren (Fach-)Publikum bekannt gemacht zu werden und auf diesem Weg ein großes Quantum Aufmerksamkeit auf sich zu ziehen. Dies gelang einem Beschluss des LG Oldenburg, {\"u}ber den Interessierte z. B. via „Juristischer Flurfunk" oder „LTO" im Dezember 2022 informiert worden sind. In der Begr{\"u}ndung dieser Beschwerdeentscheidung bemerken die Richter beil{\"a}ufig, dass ein E-Scooter von mehreren Benutzern gleichzeitig „in einer Art Mitt{\"a}terschaft" gef{\"u}hrt werden k{\"o}nne. Der Verfasser des Beschlusses war sich wohl unsicher, ob die beiden E-Scooter-Fahrer in dem konkreten Fall wirklich Mitt{\"a}ter im Sinne des \S STGB \S 25 Abs. STGB \S 25 Absatz 2 StGB waren oder nicht. Die Formulierung „Art Mitt{\"a}terschaft" klingt wie die Antwort „jein" auf diese Frage. Sachverhalt und Entscheidung sind interessant und inspirieren zum Nachdenken dar{\"u}ber, ob und wie die Deliktstatbest{\"a}nde \S STGB \S 316 StGB und \S STVG \S 24 a StVG verwirklicht werden k{\"o}nnen, wenn nicht eine Person allein das Fahrzeug f{\"u}hrt, sondern auf dessen Fortbewegung von mehreren Nutzern eingewirkt wird. Im Folgenden sollen {\"u}ber den aktuellen verfahrensgegenst{\"a}ndlichen Sachverhalt hinaus weitere Varianten eines solchen Geschehens gew{\"u}rdigt werden.}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Notwehr gegen »Klimakleber«?}, series = {Juristenzeitung}, volume = {78}, journal = {Juristenzeitung}, number = {6}, publisher = {Mohr Siebeck}, address = {T{\"u}bingen}, issn = {0022-6882}, doi = {10.1628/jz-2023-0079}, pages = {230 -- 236}, year = {2023}, abstract = {Die verst{\"a}ndliche Ver{\"a}rgerung {\"u}ber die Behinderung des fließenden Straßenverkehrs durch Menschen, die ihre H{\"a}nde mit Sekundenkleber auf der Fahrbahn fixieren, hat Diskussionen {\"u}ber die (straf-)rechtliche Bewertung dieser Aktionen und m{\"o}glicher Gegenmaßnahmen angeregt. Ein umstrittenes Thema ist die Selbsthilfe aufgehaltener Autofahrer, die sich freie Bahn dadurch verschaffen, dass sie die festgeklebten Menschen mit physischer Gewalt von der Fahrbahn entfernen, was erhebliche Verletzungen an den festgeklebten H{\"a}nden zur Folge haben kann. Der Beitrag dreht sich um die bisher nur unvollst{\"a}ndig er{\"o}rterte Frage einer Rechtfertigung solcher Selbsthilfehandlungen gem{\"a}ß \S 32 StGB.}, language = {de} } @article{HovenMitsch2023, author = {Hoven, Elisa and Mitsch, Wolfgang}, title = {Notwehr und Notwehrexzess - Vorschlag einer neuen Formulierung der \S\S 32, 33 StGB}, series = {Goltdammer's Archiv f{\"u}r Strafrecht}, journal = {Goltdammer's Archiv f{\"u}r Strafrecht}, number = {5}, publisher = {C.F. M{\"u}ller}, address = {Heidelberg}, issn = {0017-1956}, pages = {241 -- 263}, year = {2023}, abstract = {Der in diesem Beitrag vorgestellte Entwurf eines neu formulierten Notwehrrechts war Gegenstand und Grundlage einer lebhaften Diskussion, die im Rahmen einer Online-Tagung stattgefunden hat. Neben den Mitgliedern des Kriminalpolitischen Kreises, die zum Teil an der Erstellung des Gesetzesentwurfes mitgearbeitet hatten, waren weitere Experten und Interessierte beteiligt. Daraus resultierten wertvolle kritische Anmerkungen, die von der Arbeitsgruppe dankbar aufgenommen und umgesetzt wurden.}, language = {de} } @phdthesis{Mirzaee2024, author = {Mirzaee, Zohreh}, title = {Ecology and phylogeny of Mantodea of Iran and adjacent areas}, doi = {10.25932/publishup-65273}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-652739}, school = {Universit{\"a}t Potsdam}, pages = {187}, year = {2024}, abstract = {Mantodea, commonly known as mantids, have captivated researchers owing to their enigmatic behavior and ecological significance. This order comprises a diverse array of predatory insects, boasting over 2,400 species globally and inhabiting a wide spectrum of ecosystems. In Iran, the mantid fauna displays remarkable diversity, yet numerous facets of this fauna remain poorly understood, with a significant dearth of systematic and ecological research. This substantial knowledge gap underscores the pressing need for a comprehensive study to advance our understanding of Mantodea in Iran and its neighboring regions. The principal objective of this investigation was to delve into the ecology and phylogeny of Mantodea within these areas. To accomplish this, our research efforts concentrated on three distinct genera within Iranian Mantodea. These genera were selected due to their limited existing knowledge base and feasibility for in-depth study. Our comprehensive methodology encompassed a multifaceted approach, integrating morphological analysis, molecular techniques, and ecological observations. Our research encompassed a comprehensive revision of the genus Holaptilon, resulting in the description of four previously unknown species. This extensive effort substantially advanced our understanding of the ecological roles played by Holaptilon and refined its systematic classification. Furthermore, our investigation into Nilomantis floweri expanded its known distribution range to include Iran. By conducting thorough biological assessments, genetic analyses, and ecological niche modeling, we obtained invaluable insights into distribution patterns and genetic diversity within this species. Additionally, our research provided a thorough comprehension of the life cycle, behaviors, and ecological niche modeling of Blepharopsis mendica, shedding new light on the distinctive characteristics of this mantid species. Moreover, we contributed essential knowledge about parasitoids that infect mantid ootheca, laying the foundation for future studies aimed at uncovering the intricate mechanisms governing ecological and evolutionary interactions between parasitoids and Mantodea.}, language = {en} } @phdthesis{Mielke2024, author = {Mielke, Lucas}, title = {Schernikau und die Poetik der Affirmation}, series = {Deutsche Literatur : Studien und Quellen}, volume = {48}, journal = {Deutsche Literatur : Studien und Quellen}, publisher = {De Gruyter}, address = {Berlin ; Boston, Mass}, isbn = {9783111441221}, issn = {2198-932X}, doi = {10.1515/9783111441221}, pages = {vi; 241}, year = {2024}, abstract = {Die Arbeit ist der Versuch einer zusammenh{\"a}ngenden historisierenden Lekt{\"u}re der wichtigsten Essays und fiktionalen Prosatexte des Schriftstellers Ronald M. Schernikau (1960-1991). Der schwule Kommunist erkl{\"a}rte das Lob zur k{\"u}nstlerischen Strategie, formulierte gleichzeitig eine avancierte Gesellschaftskritik und verteidigte den realen Sozialismus auch gegen die Realit{\"a}t. Im Verlauf mehrerer Einzelstudien werden Themen, Schreibweisen und schließlich auch die Widerspr{\"u}che, in die sich ein solches Projekt verstricken muss, analysiert. Vor dem Hintergrund zentraler politischer und {\"a}sthetischer Debatten der 1970er und -80er Jahre werden so die Umrisse einer politischen Poetik nachgezeichnet, die der Sch{\"o}nheit verpflichtet ist. Ein weiteres Augenmerk liegt dabei auf theorie- und bewegungsgeschichtlichen Aspekten. Gibt es ein schwules Schreiben jenseits einer auktorialen Selbstpositionierung? Was w{\"u}rde eine kommunistische Literatur auszeichnen? Schernikau verhandelt poetologische Fragen um die Konzepte Autorschaft, Realismus und Werk, die nicht nur an gegenw{\"a}rtige Diskurse anschlussf{\"a}hig sind, sondern auf die Kernprobleme der politischen Literatur des Zwanzigsten Jahrhunderts verweisen.}, language = {de} } @phdthesis{Shigeyama2024, author = {Shigeyama, Jotaro}, title = {Virtual reality at 1:1 scale in small physical spaces}, doi = {10.25932/publishup-64900}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-649000}, school = {Universit{\"a}t Potsdam}, pages = {115}, year = {2024}, abstract = {Virtual Reality (VR) leads to the highest level of immersion if presented using a 1:1 mapping of virtual space to physical space—also known as real walking. The advent of inexpensive consumer virtual reality (VR) headsets, all capable of running inside-out position tracking, has brought VR to the home. However, many VR applications do not feature full real walking, but instead, feature a less immersive space-saving technique known as instant teleportation. Given that only 0.3\% of home users run their VR experiences in spaces more than 4m2, the most likely explanation is the lack of the physical space required for meaningful use of real walking. In this thesis, we investigate how to overcome this hurdle. We demonstrate how to run 1:1-mapped VR experiences in small physical spaces and we explore the trade-off between space and immersion. (1) We start with a space limit of 15cm. We present DualPanto, a device that allows (blind) VR users to experience the virtual world from a 1:1 mapped bird's eye perspective—by leveraging haptics. (2) We then relax our space constraints to 50cm, which is what seated users (e.g., on an airplane or train ride) have at their disposal. We leverage the space to represent a standing user in 1:1 mapping, while only compressing the user's arm movement. We demonstrate our 4 prototype VirtualArms at the example of VR experiences limited to arm movement, such as boxing. (3) Finally, we relax our space constraints further to 3m2 of walkable space, which is what 75\% of home users have access to. As well- established in the literature, we implement real walking with the help of portals, also known as "impossible spaces". While impossible spaces on such dramatic space constraints tend to degenerate into incomprehensible mazes (as demonstrated, for example, by "TraVRsal"), we propose plausibleSpaces: presenting meaningful virtual worlds by adapting various visual elements to impossible spaces. Our techniques push the boundary of spatially meaningful VR interaction in various small spaces. We see further future challenges for new design approaches to immersive VR experiences for the smallest physical spaces in our daily life.}, language = {en} } @phdthesis{Odanga2024, author = {Odanga, Denish Otieno}, title = {Phobic cosmopolitanism}, school = {Universit{\"a}t Potsdam}, pages = {vi ; 211}, year = {2024}, language = {en} } @phdthesis{Kaun2024, author = {Kaun, Mario}, title = {Begrenztes Cottbus?}, series = {Schriften des Fr{\"u}hneuzeitzentrums Potsdam}, volume = {13}, journal = {Schriften des Fr{\"u}hneuzeitzentrums Potsdam}, publisher = {V \& R Unipress}, address = {G{\"o}ttingen}, isbn = {978-3-8471-1726-1}, issn = {2198-5251}, pages = {311}, year = {2024}, abstract = {In diesem Band erm{\"o}glicht Mario Kaun ausgew{\"a}hlte Einblicke in die Lebenswelt der Cottbuser Exklavengesellschaft des 18. Jahrhunderts. Erstmalig erscheint hiermit f{\"u}r diesen Untersuchungsraum eine grundlegende Studie, die in umfassender Weise die Exklave und das Verh{\"a}ltnis von Milit{\"a}r und Gesellschaft n{\"a}her erforscht sowie die wirtschaftliche Funktion der Garnison in einer aufstrebenden Stadt kritisch hinterfragt. Der Autor lenkt hierbei das Augenmerk auf etliche, bisher v{\"o}llig unbekannte Perspektiven, die dar{\"u}ber hinaus einen wichtigen Beitrag zur Stadt- und Regionalgeschichtsforschung von Cottbus und der Niederlausitz leisten. Insbesondere die Befassung mit der brandenburgisch-preußischen Exklave stellt eine wertvolle Erg{\"a}nzung zur bislang rudiment{\"a}ren Forschungslage dar.}, language = {de} } @phdthesis{Karakas2024, author = {Karakas, Esra}, title = {High-resolution studies of epistasis in tomato metabolism}, school = {Universit{\"a}t Potsdam}, pages = {137}, year = {2024}, abstract = {The inclusion of exotic germplasm serves as a crucial means to enhance allelic and consequently phenotypic diversity in inbred crop species. Such species have experienced a reduction in diversity due to artificial selection focused on a limited set of traits. The natural biodiversity within ecosystems presents an opportunity to explore various traits influencing plant survival, reproductive fitness and yield potential. In agricultural research, the study of wild species closely related to cultivated plants serves as a means to comprehend the genetic foundations of past domestication events and the polymorphisms essential for future breeding efforts to develop superior varieties. In order to examine the metabolic composition, pinpoint quantitative trait loci (QTL) and facilitate their resolution an extensive large-scale analysis of metabolic QTL (mQTL) was conducted on tomato backcross inbred lines (BILs) derived from a cross between the wild species S. pennellii (5240) incorporated into the background of S. lycopersicum cv. LEA determinate inbred which can be grown in open fields and cv. TOP indeterminate which can be grown in greenhouse conditions. A large number of mQTL associated with primary secondary and lipid metabolism in fruit were identified across the two BIL populations. Epistasis, the interactions between genes at different loci, has been an interest in molecular and quantitative genetics for many decades. The study of epistasis requires the analysis of very large populations with multiple independent genotypes that carry specific genomic regions. In order to understand the genetic basis of tomato fruit metabolism, I extended the work to investigate epistatic interactions of the genomic regions. In addition, two candidate genes were identified through quantitative trait loci underlying fruit-specific sucrose and jasmonic acid derivatives. Finally, in this study, I assessed the genetic framework of fruit metabolic traits with a high level of detail, utilizing the newly created Solanum pennellii (5240) backcrossed introgression lines (n=3000). This investigation resulted in the discovery of promising candidate loci associated with significant fruit quality traits, including those to the abundance of glutamic acid and aspartic acid crucial elements contributing to the development of acidity and flavors.}, language = {en} } @periodical{OPUS4-65268, title = {Product compliance}, editor = {Bickenbach, Christian and Eichelberger, Jan and Paschke, Anne and Steinr{\"o}tter, Bj{\"o}rn and Th{\"o}ne, Meik and Waßmer, Martin Paul and Wende, Susanne and Wendt, Janine}, publisher = {Nomos}, address = {Baden-Baden}, issn = {2943-0712}, abstract = {Die Anforderungen an Unternehmen, die Waren als Hersteller produzieren, importieren oder auf dem Markt bereitstellen, werden immer komplexer. Sie m{\"u}ssen nicht nur Rechtsvorschriften einhalten, sondern auch zahlreiche produktrelevante und technische Vorgaben beachten. Product Compliance ist damit zu einer grundlegenden Aufgabe produzierender Betriebe, importierender Unternehmen und von H{\"a}ndlern geworden. Die Schriftenreihe „Product Compliance" nimmt sich der produktrechtlichen Fragestellungen rechtsgebiets{\"u}bergreifend an und dient als Forum f{\"u}r herausragende Monographien und Sammelb{\"a}nde.}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Kinder- und jugendpornographische Inhalte (\S\S 184b, 184c StGB) und \S 30 StGB}, series = {KriPoZ : kriminalpolitische Zeitschrift}, volume = {8}, journal = {KriPoZ : kriminalpolitische Zeitschrift}, number = {4}, publisher = {Universit{\"a}t zu K{\"o}ln}, address = {K{\"o}ln}, issn = {2509-6826}, pages = {249 -- 253}, year = {2023}, abstract = {Dass unser geltendes Strafrecht eine „Verschlankung" vertragen k{\"o}nnte, ist nun auch im Bundesjustizministerium bemerkt worden. Aus dem Besonderen Teil sollen Vorschriften entfernt werden, die aus unterschiedlichen Gr{\"u}nden nicht (mehr) ben{\"o}tigt werden. Als weitere Maßnahme der Entkriminalisierung steht m{\"o}glicherweise die punktuelle Senkung von Strafrahmen auf der Agenda. Dies hat nicht nur eine Reduzierung des Sanktionsniveaus zur Folge, sondern kann dort, wo infolge der niedrigeren Strafrahmenuntergrenze aus Verbrechen Vergehen werden, Straflosigkeit bewirken. Das betrifft \S 30 StGB, eine Vorschrift, die Anlass f{\"u}r die {\"U}berlegungen sein kann, nicht nur im Besonderen Teil, sondern auch im Allgemeinen Teil des StGB nach entbehrlichen Normen zu suchen. \S 30 StGB ist aktuell anwendbar in Kombination mit den Tatbestandsvarianten des \S 184b StGB, die Verbrechenscharakter haben. Welche strafrechtlichen Ergebnisse daraus resultieren k{\"o}nnen, ist in der Debatte um die Strafbarkeit von Kinderpornographie bislang nicht er{\"o}rtert worden. Dasselbe gilt f{\"u}r den praktisch selten zur Anwendung kommenden \S 16 Abs. 2 StGB, der neuerdings in Verbindung mit \S 184b StGB und \S 184c StGB in Erscheinung getreten ist. Aus der Betrachtung der Zusammenh{\"a}nge dieser Vorschriften lassen sich einige Empfehlungen an die Gesetzgebung ableiten.}, language = {de} } @article{Mitsch2023, author = {Mitsch, Wolfgang}, title = {Anmerkung zur Entscheidung des BVerfG zu \S 362 Nr. 5 StPO}, series = {KriPoZ : kriminalpolitische Zeitschrift}, volume = {8}, journal = {KriPoZ : kriminalpolitische Zeitschrift}, number = {6}, publisher = {Universit{\"a}t zu K{\"o}ln}, address = {K{\"o}ln}, issn = {2509-6826}, pages = {498 -- 501}, year = {2023}, abstract = {Mit Urteil vom 31. Oktober 2023 hat der 2. Senat des BVerfG die im Dezember 2021 durch „Gesetz zur Herstellung materieller Gerechtigkeit" eingef{\"u}hrte Vorschrift \S 362 Nr. 5 StPO f{\"u}r mit dem Grundgesetz unvereinbar und deshalb nichtig erkl{\"a}rt. Erwartungsgem{\"a}ß waren die Reaktionen auf diese Entscheidung nicht nur zustimmende. Die vorliegende Anmerkung wendet sich nicht gegen das Ergebnis, setzt sich aber - auch kritisch - mit einigen Teilen der Entscheidungsbegr{\"u}ndung sowie den Erwiderungen der beiden abweichend votierenden Senatsmitglieder auseinander.}, language = {de} } @misc{MeythalerBaumannKrasnovaetal.2023, author = {Meythaler, Antonia and Baumann, Annika and Krasnova, Hanna and Hinz, Oliver and Spiekermann, Sarah}, title = {Technology for humanity}, series = {Business \& information systems engineering}, volume = {65}, journal = {Business \& information systems engineering}, number = {5}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, issn = {2363-7005}, doi = {10.1007/s12599-023-00831-w}, pages = {487 -- 496}, year = {2023}, language = {en} } @article{MatzWangKulshreshthaetal.2022, author = {Matz, Timon W. and Wang, Yang and Kulshreshtha, Ritika and Sampathkumar, Arun and Nikoloski, Zoran}, title = {Topological properties accurately predict cell division events and organization of shoot apical meristem in Arabidopsis thaliana}, series = {Development : Company of Biologists}, volume = {149}, journal = {Development : Company of Biologists}, number = {16}, publisher = {Company of Biologists}, address = {Cambridge}, issn = {0950-1991}, doi = {10.1242/dev.201024}, pages = {11}, year = {2022}, abstract = {Cell division and the resulting changes to the cell organization affect the shape and functionality of all tissues. Thus, understanding the determinants of the tissue-wide changes imposed by cell division is a key question in developmental biology. Here, we use a network representation of live cell imaging data from shoot apical meristems (SAMs) in Arabidopsis thaliana to predict cell division events and their consequences at the tissue level. We show that a support vector machine classifier based on the SAM network properties is predictive of cell division events, with test accuracy of 76\%, which matches that based on cell size alone. Furthermore, we demonstrate that the combination of topological and biological properties, including cell size, perimeter, distance and shared cell wall between cells, can further boost the prediction accuracy of resulting changes in topology triggered by cell division. Using our classifiers, we demonstrate the importance of microtubule-mediated cell-to-cell growth coordination in influencing tissue-level topology. Together, the results from our network-based analysis demonstrate a feedback mechanism between tissue topology and cell division in A. thaliana SAMs.}, language = {en} } @article{MollavaliBoernke2022, author = {Mollavali, Mohanna and B{\"o}rnke, Frederik}, title = {Characterization of trehalose-6-phosphate synthase and trehalose-6-phosphate phosphatase genes of tomato (Solanum lycopersicum L.) and analysis of their differential expression in response to temperature}, series = {International journal of molecular sciences}, volume = {23}, journal = {International journal of molecular sciences}, number = {19}, publisher = {MDPI}, address = {Basel}, issn = {1661-6596}, doi = {10.3390/ijms231911436}, pages = {17}, year = {2022}, abstract = {In plants, the trehalose biosynthetic pathway plays key roles in the regulation of carbon allocation and stress adaptation. Engineering of the pathway holds great promise to increase the stress resilience of crop plants. The synthesis of trehalose proceeds by a two-step pathway in which a trehalose-phosphate synthase (TPS) uses UDP-glucose and glucose-6-phosphate to produce trehalose-6 phosphate (T6P) that is subsequently dephosphorylated by trehalose-6 phosphate phosphatase (TPP). While plants usually do not accumulate high amounts of trehalose, their genome encodes large families of putative trehalose biosynthesis genes, with many members lacking obvious enzymatic activity. Thus, the function of putative trehalose biosynthetic proteins in plants is only vaguely understood. To gain a deeper insight into the role of trehalose biosynthetic proteins in crops, we assessed the enzymatic activity of the TPS/TPP family from tomato (Solanum lycopersicum L.) and investigated their expression pattern in different tissues as well as in response to temperature shifts. From the 10 TPS isoforms tested, only the 2 proteins belonging to class I showed enzymatic activity, while all 5 TPP isoforms investigated were catalytically active. Most of the TPS/TPP family members showed the highest expression in mature leaves, and promoter-reporter gene studies suggest that the two class I TPS genes have largely overlapping expression patterns within the vasculature, with only subtle differences in expression in fruits and flowers. The majority of tomato TPS/TPP genes were induced by heat stress, and individual family members also responded to cold. This suggests that trehalose biosynthetic pathway genes could play an important role during temperature stress adaptation. In summary, our study represents a further step toward the exploitation of the TPS and TPP gene families for the improvement of tomato stress resistance.}, language = {en} } @article{NickelsLampeMasonetal.2022, author = {Nickels, Lyndsey and Lampe, Leonie F. and Mason, Catherine and Hameau, Solene}, title = {Investigating the influence of semantic factors on word retrieval}, series = {Cognitive neuropsychology}, volume = {39}, journal = {Cognitive neuropsychology}, number = {3-4}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0264-3294}, doi = {10.1080/02643294.2022.2109958}, pages = {113 -- 154}, year = {2022}, abstract = {There is consensus that word retrieval starts with activation of semantic representations. However, in adults without language impairment, relatively little attention has been paid to the effects of the semantic attributes of to-be-retrieved words. This paper, therefore, addresses the question of which item-inherent semantic factors influence word retrieval. Specifically, it reviews the literature on a selection of these factors: imageability, concreteness, number of semantic features, typicality, intercorrelational density, featural distinctiveness, concept distinctiveness, animacy, semantic neighbourhood density, semantic similarity, operativity, valence, and arousal. It highlights several methodological challenges in this field, and has a focus on the insights from studies with people with aphasia where the effects of these variables are more prevalent. The paper concludes that further research simultaneously examining the effects of different semantic factors that are likely to affect lexical co-activation, and the interaction of these variables, would be fruitful, as would suitably scaled computational modelling of these effects in unimpaired language processing and in language impairment. Such research would enable the refinement of theories of semantic processing and word production, and potentially have implications for diagnosis and treatment of semantic and lexical impairments.}, language = {en} } @article{SerranoMunozRovedaKupschetal.2022, author = {Serrano-Munoz, Itziar and Roveda, Ilaria and Kupsch, Andreas and M{\"u}ller, Bernd R. and Bruno, Giovanni}, title = {Synchrotron X-ray refraction detects microstructure and porosity evolution during in-situ heat treatments}, series = {Materials Science and Engineering A: Structural Materials: Properties, Microstructure and Processing}, volume = {838}, journal = {Materials Science and Engineering A: Structural Materials: Properties, Microstructure and Processing}, publisher = {Elsevier}, address = {Lausanne}, issn = {0921-5093}, doi = {10.1016/j.msea.2022.142732}, pages = {11}, year = {2022}, abstract = {For the first time, synchrotron X-ray refraction radiography (SXRR) has been paired with in-situ heat treatment to monitor microstructure and porosity evolution as a function of temperature. The investigated material was a laser powder bed fusion (LPBF) manufactured AlSi10Mg, where the initial eutectic Si network is known to disintegrate and spherodize into larger particles with increasing temperature. Such alloy is also prone to ther-mally induced porosity (TIP). We show that SXRR allows detecting the changes in the Si-phase morphology upon heating, while this is currently possible only using scanning electron microscopy. SXRR also allows observing the growth of pores, usually studied via X-ray computed tomography, but on much smaller fields-of-view. Our results show the great potential of in-situ SXRR as a tool to gain in-depth knowledge of the susceptibility of any material to thermally induced damage and/or microstructure evolution over statistically relevant volumes.}, language = {en} } @article{LehnenKurkiHartlieb2022, author = {Lehnen, Anne-Catherine and Kurki, Jan A. M. and Hartlieb, Matthias}, title = {The difference between photo-iniferter and conventional RAFT polymerization}, series = {Polymer Chemistry}, volume = {13}, journal = {Polymer Chemistry}, number = {11}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1759-9954}, doi = {10.1039/d1py01530c}, pages = {1537 -- 1546}, year = {2022}, abstract = {Photo-iniferter (PI)-RAFT polymerization, the direct activation of chain transfer agents via light, is a fascinating polymerization technique, as it overcomes some restriction of conventional RAFT polymerization. As such, we elucidated the role of reversible deactivation in this context using a monomer-CTA pair with low chain transfer capabilities. Tests with varying targeted degrees of polymerization (DP) or monomer concentrations revealed no significant improvement of polymerization control using the PI-process. Control can however be achieved via slow monomer addition, increasing the number of activation/deactivation events per monomer addition. More importantly, the livingness of the polymerization was found to be extraordinarily high, enabling the straightforward and rapid synthesis of multiblock copolymers with up to 20 blocks and a high number of repeating units per block (DP = 25-100) maintaining an overall excellent definition (M-n = 90 300 g mol(-1), D = 1.29). This study highlights the enormous potential of PI-RAFT polymerization for the synthesis of polymeric materials.}, language = {en} } @article{SchladebachSchlusnath2024, author = {Schladebach, Marcus and Schlusnath, Elsa Marie}, title = {Klausur im Medienrecht}, series = {JURA : juristische Ausbildung}, volume = {46}, journal = {JURA : juristische Ausbildung}, number = {8}, publisher = {De Gruyter}, address = {Berlin}, issn = {0170-1452}, doi = {10.1515/jura-2024-2095}, pages = {840 -- 846}, year = {2024}, abstract = {Die Privatsph{\"a}re prominenter Personen wird h{\"a}ufig durch eine auf Sensationsgier ausgerichtete Presseberichterstattung gef{\"a}hrdet. W{\"a}hrend sich die Presse dabei vordergr{\"u}ndig auf ein {\"o}ffentliches Interesse an solchen Berichten beruft, kann die Reputation der Betroffenen in der {\"O}ffentlichkeit stark und dauerhaft beeintr{\"a}chtigt werden. Jedoch folgen aus dem Allgemeinen Pers{\"o}nlichkeitsrecht mehrere Anspr{\"u}che, mit denen diese Rechtsverletzungen abgewehrt und m{\"o}gliche Sch{\"a}den kompensiert werden k{\"o}nnen.}, language = {de} } @article{BiloBiloLenzneretal.2022, author = {Bilo, Davide and Bilo, Vittorio and Lenzner, Pascal and Molitor, Louise}, title = {Topological influence and locality in swap schelling games}, series = {Autonomous Agents and Multi-Agent Systems}, volume = {36}, journal = {Autonomous Agents and Multi-Agent Systems}, number = {2}, publisher = {Springer}, address = {Dordrecht}, issn = {1387-2532}, doi = {10.1007/s10458-022-09573-7}, pages = {60}, year = {2022}, abstract = {Residential segregation is a wide-spread phenomenon that can be observed in almost every major city. In these urban areas residents with different racial or socioeconomic background tend to form homogeneous clusters. Schelling's famous agent-based model for residential segregation explains how such clusters can form even if all agents are tolerant, i.e., if they agree to live in mixed neighborhoods. For segregation to occur, all it needs is a slight bias towards agents preferring similar neighbors. Very recently, Schelling's model has been investigated from a game-theoretic point of view with selfish agents that strategically select their residential location. In these games, agents can improve on their current location by performing a location swap with another agent who is willing to swap. We significantly deepen these investigations by studying the influence of the underlying topology modeling the residential area on the existence of equilibria, the Price of Anarchy and on the dynamic properties of the resulting strategic multi-agent system. Moreover, as a new conceptual contribution, we also consider the influence of locality, i.e., if the location swaps are restricted to swaps of neighboring agents. We give improved almost tight bounds on the Price of Anarchy for arbitrary underlying graphs and we present (almost) tight bounds for regular graphs, paths and cycles. Moreover, we give almost tight bounds for grids, which are commonly used in empirical studies. For grids we also show that locality has a severe impact on the game dynamics.}, language = {en} } @article{LimmerothRaboldt2022, author = {Limmeroth, Julia and Raboldt, Michaela}, title = {"I do what I like": 8-to 10-year-old children's physical activity behavior is already interrelated with their automatic affective processes}, series = {Journal of sport \& exercise psychology}, volume = {44}, journal = {Journal of sport \& exercise psychology}, number = {2}, publisher = {Human Kinetics Publ.}, address = {Champaign}, issn = {0895-2779}, doi = {10.1123/jsep.2021-0251}, pages = {138 -- 147}, year = {2022}, abstract = {The majority of middle-age children do not meet current physical activity guidelines. There is growing evidence that adults' physical activity is partially influenced by automatic affective processes, which are derived from affective experiences with physical activity. However, little is known about whether these processes are interrelated with children's physical activity level. A prospective design was used to examine whether automatic affective processes assessed by an evaluative priming procedure predict physical activity of children. Physical activity of 48 children (8.71 +/- 0.71 years; 65\% girls) was measured for 1 week with activity trackers. In a linear regression model, automatic affective processes (beta = 0.36) significantly predicted physical activity, accounting for 11.02\% of variance. These results indicate that physical-activity-related automatic affective processes are associated with children's physical activity, as has previously been found in adults. This study emphasizes the importance of fostering positive affective experiences associated with physical activity during childhood.}, language = {en} } @article{GleissDegenKnothetal.2023, author = {Gleiß, Alexander and Degen, Konrad and Knoth, Alexander and Pousttchi, Key and Lucke, Ulrike}, title = {Governance principles and regulatory needs for a national digital education platform}, series = {Public policy and administration}, journal = {Public policy and administration}, publisher = {Sage}, address = {London}, issn = {0952-0767}, doi = {10.1177/09520767231202327}, pages = {1 -- 31}, year = {2023}, abstract = {The educational sector currently faces a massive digital transformation with various digital offerings entering the market. To provide some orientation in this transforming space, a national digital education platform (NDEP) is under development in Germany as part of a nationwide flagship project. On the one hand, in efficiently connecting the relevant stakeholders to each other and to value-adding education-related offerings, various benefits emerge. On the other hand, monopolising the educational sector and influencing the respective market through a state-controlled platform bears potential regulatory risks from misuse of power by the platform to malpractice by the users. Against this background, we aim to identify and systematise these potential drawbacks prior to the platform's actual development and implementation. We pursue a qualitative, interpretivist approach for policy analysis, based on ten elite interviews and two workshops. Our results are threefold: (1) We capture the consolidated NDEP architecture; (2) We categorise the range of relevant functions and value propositions of the NDEP; (3) We derive 23 regulatory areas of conflict across the three building blocks that result from the potential ecosystem and function scope configurations of the NDEP. As a contribution to research, we shed new interdisciplinary light on the governance and infrastructure of public-private platforms that enable innovation and collaboration while integrating respective market segments. As a contribution to practice, we provide clear guidance for policy-makers in strategizing the development and governance of and through national digital platforms in education.}, language = {en} } @article{MuschallaBaronKlevers2022, author = {Muschalla, Beate and Baron, Stefanie and Klevers, Theresa}, title = {Students or medical professionals: whose knowledge improved after social-medicine training?}, series = {Social Psychiatry \& Psychiatric Epidemiology}, volume = {57}, journal = {Social Psychiatry \& Psychiatric Epidemiology}, number = {7}, publisher = {Springer}, address = {Heidelberg}, issn = {0933-7954}, doi = {10.1007/s00127-021-02197-4}, pages = {1505 -- 1514}, year = {2022}, abstract = {Purpose Rehabilitation professionals are faced with judging and describing the social-medicine status of their patients. Rehabilitation professionals must know the core concepts of acute unfitness for work, psychological capacities, and long-term work capacity. Acquiring and applying this knowledge, requires training. The research question is if and to what extent medical professionals and students' knowledge changes after social medicine training. Methods This quasi-experimental study was carried out in the real-life context of social medicine training. Psychology students (n = 42), physicians/psychotherapists (i.e. state-licensed health professionals) (n = 44) and medical assistant professionals (n = 29) were trained. Their social medicine knowledge was measured before and after training by a 10-min expert-approved and content valid knowledge questionnaire. Three free-text questions had to be answered on the essential aspects of present and prognostic work ability and psychological capacities. Answers were rated for correctness by two experts. Paired t tests and variance analysis have been calculated for group comparisons. Results All groups improved their social medicine knowledge from the pre- to the post-test. The students started with the lowest level of knowledge in the pre-test. After training, 69\% of the physicians/psychotherapists and 56.8\% of the medical assistant professionals, but only 7\% of the students, obtained maximum scores for naming psychological capacities. Conclusions Social medicine knowledge increased after a training course consisting of eight lessons. The increase was greater for medical assistant professionals and physicians/psychotherapists than for students. Social medicine training must be adjusted to the trainee groups' knowledge levels.}, language = {en} } @article{CreutzigBeckerBerrilletal.2024, author = {Creutzig, Felix and Becker, Sophia and Berrill, Peter and Bongs, Constanze and Bussler, Alexandra and Cave, Ben and Constantino, Sara M. and Grant, Marcus and Heeren, Niko and Heinen, Eva and Hintz, Marie Josefine and Ingen-Housz, Timothee and Johnson, Eric and Kolleck, Nina and Liotta, Charlotte and Lorek, Sylvia and Mattioli, Giulio and Niamir, Leila and McPhearson, Timon and Milojevic-Dupont, Nikola and Nachtigall, Florian and Nagel, Kai and N{\"a}rger, Henriette and Pathak, Minal and Perrin de Brichambaut, Paola and Reckien, Diana and Reisch, Lucia A. and Revi, Aromar and Schuppert, Fabian and Sudmant, Andrew and Wagner, Felix and Walkenhorst, Janina and Weber, Elke and Wilmes, Michael and Wilson, Charlie and Zekar, Aicha}, title = {Towards a public policy of cities and human settlements in the 21st century}, series = {npj urban sustainability}, volume = {4}, journal = {npj urban sustainability}, number = {1}, publisher = {Springer Nature}, address = {London}, issn = {2661-8001}, doi = {10.1038/s42949-024-00168-7}, pages = {1 -- 14}, year = {2024}, abstract = {Cities and other human settlements are major contributors to climate change and are highly vulnerable to its impacts. They are also uniquely positioned to reduce greenhouse gas emissions and lead adaptation efforts. These compound challenges and opportunities require a comprehensive perspective on the public policy of human settlements. Drawing on core literature that has driven debate around cities and climate over recent decades, we put forward a set of boundary objects that can be applied to connect the knowledge of epistemic communities and support an integrated urbanism. We then use these boundary objects to develop the Goals-Intervention-Stakeholder-Enablers (GISE) framework for a public policy of human settlements that is both place-specific and provides insights and tools useful for climate action in cities and other human settlements worldwide. Using examples from Berlin, we apply this framework to show that climate mitigation and adaptation, public health, and well-being goals are closely linked and mutually supportive when a comprehensive approach to urban public policy is applied.}, language = {en} } @article{ScherbaumMzhavanadzeRosenzweigetal.2022, author = {Scherbaum, Frank and Mzhavanadze, Nana and Rosenzweig, Sebastian and M{\"u}ller, Meinard}, title = {Tuning systems of traditional Georgian singing determined from a new corpus of field recordings}, series = {Musicologist}, volume = {6}, journal = {Musicologist}, number = {2}, publisher = {Trabzon Univ State Conservatory}, address = {Trabzon}, issn = {2618-5652}, doi = {10.33906/musicologist.1068947}, pages = {142 -- 168}, year = {2022}, abstract = {In this study we examine the tonal organization of the 2016 GVM dataset, a newly-created corpus of high-quality multimedia field recordings of traditional Georgian singing with a focus on Svaneti. For this purpose, we developed a new processing pipeline for the computational analysis of non-western polyphonic music which was subsequently applied to the complete 2016 GVM dataset. To evaluate under what conditions a single tuning system is representative of current Svan performance practice, we examined the stability of the obtained tuning systems from an ensemble-, a song-, and a corpus-related perspective. Furthermore, we compared the resulting Svan tuning systems with the tuning systems obtained for the Erkomaishvili dataset (Rosenzweig et al., 2020) in the study by Scherbaum et al. (2020). In comparison to a 12-TET (12-tone-equal-temperament) system, the Erkomaishvili and the Svan tuning systems are surprisingly similar. Both systems show a strong presence of pure fourths (500 cents) and fifths (700 cents), and 'neutral' thirds (peaking around 350 cents) as well as 'neutral' sixths. In addition, the sizes of the melodic and the harmonic seconds in both tuning systems differ systematically from each other, with the size of the harmonic second being systematically larger than the melodic one.}, language = {en} } @inproceedings{Gleiss2020, author = {Gleiß, Alexander}, title = {The patient will see you now-towards an understanding of on-demand healthcare}, series = {2020 IEEE 22nd Conference on Business Informatics (CBI)}, booktitle = {2020 IEEE 22nd Conference on Business Informatics (CBI)}, publisher = {IEEE}, address = {Piscataway}, isbn = {978-1-7281-9926-9}, doi = {10.1109/CBI49978.2020.00024}, pages = {154 -- 161}, year = {2020}, abstract = {The increasing prevalence and ubiquity of digital technologies is changing the needs and expectations of patients towards healthcare services. As a result, a plethora of patient-centered services edges into the healthcare market. Since digital technologies bear the potential to surmount barriers in time and space, patients increasingly demand real-time or near-time healthcare services. Amongst a cloud of related concepts in the context of digital health, one term increasingly typifies this impulse: on-demand healthcare. While this term can be noticeably found in practice, there is hardly some theoretical foundation so far. Against this background, the aim of this paper is to address this research gap and to explore the phenomenon of on-demand healthcare. Based on a design-science approach including a literature review and analysis of in-depth interviews and empirical cases, the outcome of this paper is twofold: (1) a conceptual framework and (2) a proposal for a definition of on-demand healthcare.}, language = {en} } @article{GrafLaskowskiPapsdorfetal.2022, author = {Graf, Martin and Laskowski, Lukas and Papsdorf, Florian and Sold, Florian and Gremmelspacher, Roland and Naumann, Felix and Panse, Fabian}, title = {Frost: a platform for benchmarking and exploring data matching results}, series = {Proceedings of the VLDB Endowment}, volume = {15}, journal = {Proceedings of the VLDB Endowment}, number = {12}, publisher = {Association for Computing Machinery}, address = {New York}, issn = {2150-8097}, doi = {10.14778/3554821.3554823}, pages = {3292 -- 3305}, year = {2022}, abstract = {"Bad" data has a direct impact on 88\% of companies, with the average company losing 12\% of its revenue due to it. Duplicates - multiple but different representations of the same real-world entities are among the main reasons for poor data quality, so finding and configuring the right deduplication solution is essential. Existing data matching benchmarks focus on the quality of matching results and neglect other important factors, such as business requirements. Additionally, they often do not support the exploration of data matching results. To address this gap between the mere counting of record pairs vs. a comprehensive means to evaluate data matching solutions, we present the Frost platform. It combines existing benchmarks, established quality metrics, cost and effort metrics, and exploration techniques, making it the first platform to allow systematic exploration to understand matching results. Frost is implemented and published in the open-source application Snowman, which includes the visual exploration of matching results, as shown in Figure 1.}, language = {en} } @inproceedings{DehnertGleissReiss2021, author = {Dehnert, Maik and Gleiß, Alexander and Reiss, Frederick}, title = {What makes a data-driven business model?}, series = {ECIS Proceedings 2021}, booktitle = {ECIS Proceedings 2021}, publisher = {AIS}, address = {Atlanta}, isbn = {978-1-7336325-6-0}, year = {2021}, abstract = {The usage of data to improve or create business models has become vital for companies in the 21st century. However, to extract value from data it is important to understand the business model. Taxonomies for data-driven business models (DDBM) aim to provide guidance for the development and ideation of new business models relying on data. In IS research, however, different taxonomies have emerged in recent years, partly redundant, partly contradictory. Thus, there is a need to synthesize the common ground of these taxonomies within IS research. Based on 26 IS-related taxonomies and 30 cases, we derive and define 14 generic building blocks of DDBM to develop a consolidated taxonomy that represents the current state-of-the-art. Thus, we integrate existing research on DDBM and provide avenues for further exploration of data-induced potentials for business models as well as for the development and analysis of general or industry-specific DDBM.}, language = {en} } @article{Nehring2022, author = {Nehring, Christopher}, title = {Files, agents, "Deep State," and Russian influence: the legacy of the communist state security service in Bulgaria}, series = {International Journal of Intelligence and Counterintelligence}, volume = {35}, journal = {International Journal of Intelligence and Counterintelligence}, number = {2}, publisher = {Routledge, Taylor \& Francis Group}, address = {Abingdon}, issn = {0885-0607}, doi = {10.1080/08850607.2021.2018264}, pages = {318 -- 338}, year = {2022}, abstract = {How much influence did the former communist state security service Darzhavna sigurnost (DS) have during the transformation period in Bulgaria? For the first time in history, there is empirical data available that allow for an analysis of the role of the Bulgarian secret police and its "afterlife" after 1990. Bulgarian intelligence archives, which were made partly accessible following the country's admission to the European Union in 2007, provide an excellent basis for an analysis of the relationship between the DS and the Soviet State Committee for Security, the transformation of the Bulgarian security apparatus in 1990, attempts to disclose the state security archives, and continuous infiltration of Bulgarian politics, institutions, and security apparatus by former agents of the communist intelligence and security apparatus. The empirical data suggest that personal connections, dependencies, and informal networks of former DS agents and officials played an important role during the transformation period in Bulgaria and are at least partly responsible for political corruption, continuous Russian influence, a high degree of politicization of the Bulgarian security apparatus, misuse of intelligence and illegal surveillance practices, and a high degree of domestic and international mistrust and (dis-)loyalty.}, language = {en} } @article{DehnertSchumann2022, author = {Dehnert, Maik and Schumann, Josephine}, title = {Uncovering the digitalization impact on consumer decision-making for checking accounts in banking}, series = {Electronic markets}, volume = {32}, journal = {Electronic markets}, number = {3}, publisher = {Springer}, address = {Berlin}, issn = {1019-6781}, doi = {10.1007/s12525-022-00524-4}, pages = {1503 -- 1528}, year = {2022}, abstract = {Checking account providers must understand the importance of digital and non-digital service attributes across different customer segments to achieve a product-market fit in digitalization. In particular, various latent personal characteristics influence customer choices in digital banking. However, there is only limited research on banking customer behavior beyond the technology acceptance model, and none that explores customer preferences for checking accounts experimentally. Against this background, we present the results of a discrete choice experiment on customer preferences towards checking accounts in Germany. The outcome of the paper is a detailed quantitative assessment of the relationships between checking account service attributes and a set of latent influencing factors on choice. While customer service experience, the scope of services, and professional expertise are identified as re-occurring critical aspects for customers when choosing their banking service provider, the type of provider and digital product innovation showed little impact on customer choice overall. In multigroup analyses, we reveal the moderating impact of influencing factors on the preference of checking account service attributes. Additional segmentation analyses point to six customer segments from which four still prefer a traditional operating model. The largest segment of traditional product-innovative customers prefers digitalized, i.e., data-driven checking accounts in a mixed-mode with human customer advisory and on-site branch services from a traditional bank. At the other end of the spectrum, a small innovative Fintech customer segment, influenced by non-pragmatism and social norms, prefers a purely digital operating model with data-driven applications in banking.}, language = {en} } @inproceedings{Dehnert2020, author = {Dehnert, Maik}, title = {Organizational change toward IT-supported personal advisory in incumbent banks}, series = {Perspectives in business informatics research}, volume = {398}, booktitle = {Perspectives in business informatics research}, editor = {Buchmann, Robert Andrei and Polini, Andrea and Johansson, Bj{\"o}rn and Karagiannis, Dimitris}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-61139-2}, doi = {10.1007/978-3-030-61140-8_14}, pages = {205 -- 219}, year = {2020}, abstract = {Due to changing customer behavior in digitalization, banks urge to change their traditional value creation in order to improve interaction with customers. New digital technologies such as core banking solutions change organizational structures to provide organizational and individual affordances in IT-supported personal advisory. Based on adaptive structuration theory and with qualitative data from 24 German banks, we identify first, second and third order issues of organizational change in value creation, which are connected with a set of affordances and constraints as the outcomes for customer interaction.}, language = {en} } @book{JuizBermejoCalleetal.2024, author = {Juiz, Carlos and Bermejo, Belen and Calle, Alejandro and Sidorova, Julia and Lundberg, Lars and Weidmann, Vera and Lowitzki, Leon and Mirtschin, Marvin and Hoorn, Andr{\´e} van and Frank, Markus and Schulz, Henning and Stojanovic, Dragan and Stojanovic, Natalija and Stojnev Ilic, Aleksandra and Friedrich, Tobias and Lenzner, Pascal and Weyand, Christopher and Wagner, Markus and Plauth, Max and Polze, Andreas and Nowicki, Marek and Seth, Sugandh and Kaur Chahal, Kuljit and Singh, Gurwinder and Speth, Sandro and Janes, Andrea and Camilli, Matteo and Ziegler, Erik and Schmidberger, Marcel and P{\"o}rschke, Mats and Bartz, Christian and Lorenz, Martin and Meinel, Christoph and Beilich, Robert and Bertazioli, Dario and Carlomagno, Cristiano and Bedoni, Marzia and Messina, Vincenzina}, title = {HPI Future SOC Lab}, series = {Technische Berichte des Hasso-Plattner-Instituts f{\"u}r Digital Engineering an der Universit{\"a}t Potsdam}, journal = {Technische Berichte des Hasso-Plattner-Instituts f{\"u}r Digital Engineering an der Universit{\"a}t Potsdam}, number = {159}, editor = {Meinel, Christoph and Polze, Andreas and Beins, Karsten and Strotmann, Rolf and Seibold, Ulrich and R{\"o}dszus, Kurt and M{\"u}ller, J{\"u}rgen and Sommer, J{\"u}rgen}, publisher = {Universit{\"a}tsverlag Potsdam}, address = {Potsdam}, isbn = {978-3-86956-565-1}, issn = {1613-5652}, doi = {10.25932/publishup-59801}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-598014}, publisher = {Universit{\"a}t Potsdam}, pages = {ix, 142}, year = {2024}, abstract = {The "HPI Future SOC Lab" is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners. The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies. This technical report presents results of research projects executed in 2020. Selected projects have presented their results on April 21st and November 10th 2020 at the Future SOC Lab Day events.}, language = {en} } @article{BartoszewiczNasriNowickaetal.2022, author = {Bartoszewicz, Jakub M. and Nasri, Ferdous and Nowicka, Melania and Renard, Bernhard Y.}, title = {Detecting DNA of novel fungal pathogens using ResNets and a curated fungi-hosts data collection}, series = {Bioinformatics}, volume = {38}, journal = {Bioinformatics}, publisher = {Oxford Univ. Press}, address = {Oxford}, issn = {1367-4803}, doi = {10.1093/bioinformatics/btac495}, pages = {ii168 -- ii174}, year = {2022}, abstract = {Background: Emerging pathogens are a growing threat, but large data collections and approaches for predicting the risk associated with novel agents are limited to bacteria and viruses. Pathogenic fungi, which also pose a constant threat to public health, remain understudied. Relevant data remain comparatively scarce and scattered among many different sources, hindering the development of sequencing-based detection workflows for novel fungal pathogens. No prediction method working for agents across all three groups is available, even though the cause of an infection is often difficult to identify from symptoms alone. Results: We present a curated collection of fungal host range data, comprising records on human, animal and plant pathogens, as well as other plant-associated fungi, linked to publicly available genomes. We show that it can be used to predict the pathogenic potential of novel fungal species directly from DNA sequences with either sequence homology or deep learning. We develop learned, numerical representations of the collected genomes and visualize the landscape of fungal pathogenicity. Finally, we train multi-class models predicting if next-generation sequencing reads originate from novel fungal, bacterial or viral threats. Conclusions: The neural networks trained using our data collection enable accurate detection of novel fungal pathogens. A curated set of over 1400 genomes with host and pathogenicity metadata supports training of machine-learning models and sequence comparison, not limited to the pathogen detection task.}, language = {en} } @phdthesis{Bryant2024, author = {Bryant, Seth}, title = {Aggregation and disaggregation in flood risk models}, doi = {10.25932/publishup-65095}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-650952}, school = {Universit{\"a}t Potsdam}, pages = {ix, 116}, year = {2024}, abstract = {Floods continue to be the leading cause of economic damages and fatalities among natural disasters worldwide. As future climate and exposure changes are projected to intensify these damages, the need for more accurate and scalable flood risk models is rising. Over the past decade, macro-scale flood risk models have evolved from initial proof-of-concepts to indispensable tools for decision-making at global-, nationaland, increasingly, the local-level. This progress has been propelled by the advent of high-performance computing and the availability of global, space-based datasets. However, despite such advancements, these models are rarely validated and consistently fall short of the accuracy achieved by high-resolution local models. While capabilities have improved, significant gaps persist in understanding the behaviours of such macro-scale models, particularly their tendency to overestimate risk. This dissertation aims to address such gaps by examining the scale transfers inherent in the construction and application of coarse macroscale models. To achieve this, four studies are presented that, collectively, address exposure, hazard, and vulnerability components of risk affected by upscaling or downscaling. The first study focuses on a type of downscaling where coarse flood hazard inundation grids are enhanced to a finer resolution. While such inundation downscaling has been employed in numerous global model chains, ours is the first study to focus specifically on this component, providing an evaluation of the state of the art and a novel algorithm. Findings demonstrate that our novel algorithm is eight times faster than existing methods, offers a slight improvement in accuracy, and generates more physically coherent flood maps in hydraulically challenging regions. When applied to a case study, the algorithm generated a 4m resolution inundation map from 30m hydrodynamic model outputs in 33 s, a 60-fold improvement in runtime with a 25\% increase in RMSE compared with direct hydrodynamic modelling. All evaluated downscaling algorithms yielded better accuracy than the coarse hydrodynamic model when compared to observations, demonstrating similar limits of coarse hydrodynamic models reported by others. The substitution of downscaling into flood risk model chains, in place of high-resolution modelling, can drastically improve the lead time of impactbased forecasts and the efficiency of hazard map production. With downscaling, local regions could obtain high resolution local inundation maps by post-processing a global model without the need for expensive modelling or expertise. The second study focuses on hazard aggregation and its implications for exposure, investigating implicit aggregations commonly used to intersect hazard grids with coarse exposure models. This research introduces a novel spatial classification framework to understand the effects of rescaling flood hazard grids to a coarser resolution. The study derives closed-form analytical solutions for the location and direction of bias from flood grid aggregation, showing that bias will always be present in regions near the edge of inundation. For example, inundation area will be positively biased when water depth grids are aggregated, while volume will be negatively biased when water elevation grids are aggregated. Extending the analysis to effects of hazard aggregation on building exposure, this study shows that exposure in regions at the edge of inundation are an order of magnitude more sensitive to aggregation errors than hazard alone. Among the two aggregation routines considered, averaging water surface elevation grids better preserved flood depths at buildings than averaging of water depth grids. The study provides the first mathematical proof and generalizeable treatment of flood hazard grid aggregation, demonstrating important mechanisms to help flood risk modellers understand and control model behaviour. The final two studies focus on the aggregation of vulnerability models or flood damage functions, investigating the practice of applying per-asset functions to aggregate exposure models. Both studies extend Jensen's inequality, a well-known 1906 mathematical proof, to demonstrate how the aggregation of flood damage functions leads to bias. Applying Jensen's proof in this new context, results show that typically concave flood damage functions will introduce a positive bias (overestimation) when aggregated. This behaviour was further investigated with a simulation experiment including 2 million buildings in Germany, four global flood hazard simulations and three aggregation scenarios. The results show that positive aggregation bias is not distributed evenly in space, meaning some regions identified as "hot spots of risk" in assessments may in fact just be hot spots of aggregation bias. This study provides the first application of Jensen's inequality to explain the overestimates reported elsewhere and advice for modellers to minimize such artifacts. In total, this dissertation investigates the complex ways aggregation and disaggregation influence the behaviour of risk models, focusing on the scale-transfers underpinning macro-scale flood risk assessments. Extending a key finding of the flood hazard literature to the broader context of flood risk, this dissertation concludes that all else equal, coarse models overestimate risk. This dissertation goes beyond previous studies by providing mathematical proofs for how and where such bias emerges in aggregation routines, offering a mechanistic explanation for coarse model overestimates. It shows that this bias is spatially heterogeneous, necessitating a deep understanding of how rescaling may bias models to effectively reduce or communicate uncertainties. Further, the dissertation offers specific recommendations to help modellers minimize scale transfers in problematic regions. In conclusion, I argue that such aggregation errors are epistemic, stemming from choices in model structure, and therefore hold greater potential and impetus for study and mitigation. This deeper understanding of uncertainties is essential for improving macro-scale flood risk models and their effectiveness in equitable, holistic, and sustainable flood management.}, language = {en} } @article{HeydenNatho2022, author = {Heyden, Janika and Natho, Stephanie}, title = {Assessing floodplain management in Germany - a case study on nationwide research and actions}, series = {Sustainability}, volume = {14}, journal = {Sustainability}, number = {17}, publisher = {MDPI}, address = {Basel}, issn = {2071-1050}, doi = {10.3390/su141710610}, pages = {18}, year = {2022}, abstract = {After a long history of floodplain degradation and substantial losses of inundation areas over the last decades, a rethinking of floodplain management has taken place in Germany. Floodplains are now acknowledged as important areas for both biodiversity and society. This transformation has been significantly supported by nationwide research activities. A systematic assessment of the current floodplain management is still lacking. We therefore developed a scheme to assess floodplain management through the steps of identification, analysis, implementation, and evaluation. Reviewing the data and literature on nationwide floodplain-related research and activities, we defined key elements of floodplain management for Germany. We concluded that research activities already follow a strategic nationwide approach of identifying and analyzing floodplains. Progress in implementation is slow, however, and potentials are far from being reached. Nevertheless, new and unique initiatives enable Germany to stay on the long-term path of giving rivers more space and improving floodplain conditions.}, language = {en} } @article{GaetjenWieczorekListeketal.2022, author = {G{\"a}tjen, Dominic and Wieczorek, Marek and Listek, Martin and Tomszak, Florian and N{\"o}lle, Volker and Hanack, Katja and Droste, Miriam Susanna}, title = {A switchable secrete-and-capture system enables efficient selection of Pichia pastoris clones producing high yields of Fab fragments}, series = {Journal of immunological methods}, volume = {511}, journal = {Journal of immunological methods}, publisher = {Elsevier Science}, address = {Amsterdam [u.a.]}, issn = {0022-1759}, doi = {10.1016/j.jim.2022.113383}, pages = {14}, year = {2022}, abstract = {Pichia pastoris (syn. Komagataella phaffii) represents a commonly used expression system in the biotech industry. High clonal variation of transformants, however, typically results in a broad range of specific productivities for secreted proteins. To isolate rare clones with exceedingly high product titers, an extensive number of clones need to be screened. In contrast to high-throughput screenings of P. pastoris clones in microtiter plates, secrete-and -capture methodologies have the potential to efficiently isolate high-producer clones among millions of cells through fluorescence-activated cell sorting (FACS).Here, we describe a novel approach for the non-covalent binding of fragment antigen-binding (Fab) proteins to the cell surface for the isolation of high-producing clones. Eight different single-chain variable fragment (scFv)-based capture matrices specific for the constant part of the Fabs were fused to the Saccharomyces cerevisiae alpha -agglutinin (SAG1) anchor protein for surface display in P. pastoris. By encoding the capture matrix on an episomal plasmid harboring inherently unstable autonomously replicating sequences (ARS), this secrete-and -capture system offers a switchable scFv display. Efficient plasmid clearance upon removal of selective pres-sure enabled the direct use of isolated clones for subsequent Fab production. Flow-sorted clones (n = 276) displaying high amounts of Fabs showed a significant increase in median Fab titers detected in the cell-free supernatant (CFS) compared to unsorted clones (n = 276) when cells were cultivated in microtiter plates (fac-tor in the range of-21-49). Fab titers of clones exhibiting the highest product titer observed for each of the two approaches were increased by up to 8-fold for the sorted clone. Improved Fab yields of sorted cells vs. unsorted cells were confirmed in an upscaled shake flask cultivation of selected candidates (factor in the range of-2-3). Hence, the developed display-based selection method proved to be a valuable tool for efficient clone screening in the early stages of our bioprocess development.}, language = {en} } @article{WengerGaertnerBrunner2022, author = {Wenger, Marina and G{\"a}rtner, Holger and Brunner, Martin}, title = {Wie ver{\"a}ndert sich die Unterrichts- und Schulqualit{\"a}t, die Leistung und die Sch{\"u}lerzusammensetzung nach der Schulinspektionsdiagnose „erheblicher Entwicklungsbedarf"?}, series = {Zeitschrift f{\"u}r Erziehungswissenschaft}, volume = {25}, journal = {Zeitschrift f{\"u}r Erziehungswissenschaft}, number = {4}, publisher = {VS Verlag f{\"u}r Sozialwissenschaften ; Springer}, address = {Wiesbaden}, issn = {1434-663X}, doi = {10.1007/s11618-022-01066-3}, pages = {1031 -- 1058}, year = {2022}, abstract = {Die Schulinspektion evaluiert Schulen mit dem Ziel der Qualit{\"a}tssicherung von Unterrichts- und Schulqualit{\"a}t. Dies gilt insbesondere f{\"u}r Schulen, an denen „erheblicher Entwicklungsbedarf" festgestellt wurde. Diese Schulen bekommen zus{\"a}tzliche Unterst{\"u}tzung, erfahren aber auch zus{\"a}tzlichen Druck durch diese Einordnung. Die weitere Entwicklung dieser Schulen ist bisher kaum erforscht. Diese Studie untersucht mit Daten der Schulinspektion, der amtlichen Statistik und Leistungsdaten von 333 Berliner Grundschulen Ver{\"a}nderungen in Indikatoren der Unterrichts- und Schulqualit{\"a}t, der Schulleistung, und der Zusammensetzung der Sch{\"u}lerschaft (SES und Anteil mit nicht-deutscher Herkunftssprache) nach der Diagnose „erheblicher Entwicklungsbedarf". Die empirischen Analysen zeigten, dass sich bei diesen Schulen die Unterrichts- und Schulqualit{\"a}t nur geringf{\"u}gig ver{\"a}nderte, sich der Leistungsabstand zu allen anderen Grundschulen nicht statistisch signifikant verringerte, und sich die Zusammensetzung der Sch{\"u}lerschaft hinsichtlich des sozio{\"o}konomischen Status (SES) nicht ver{\"a}nderte. Jedoch erh{\"o}hte sich der Anteil von Kindern mit nicht-deutscher Herkunftssprache statistisch signifikant.}, language = {de} } @article{Seyedhosseini2022, author = {Seyedhosseini, Mehran}, title = {A variant of Roe algebras for spaces with cylindrical ends with applications in relative higher index theory}, series = {Journal of noncommutative geometry}, volume = {16}, journal = {Journal of noncommutative geometry}, number = {2}, publisher = {European Mathematical Society}, address = {Zurich}, issn = {1661-6952}, doi = {10.4171/JNCG/457}, pages = {595 -- 624}, year = {2022}, abstract = {In this paper, we define a variant of Roe algebras for spaces with cylindrical ends and use this to study questions regarding existence and classification of metrics of positive scalar curvature on such manifolds which are collared on the cylindrical end. We discuss how our constructions are related to relative higher index theory as developed by Chang, Weinberger, and Yu and use this relationship to define higher rho-invariants for positive scalar curvature metrics on manifolds with boundary. This paves the way for the classification of these metrics. Finally, we use the machinery developed here to give a concise proof of a result of Schick and the author, which relates the relative higher index with indices defined in the presence of positive scalar curvature on the boundary.}, language = {en} } @article{EntrichFujihara2022, author = {Entrich, Steve R. and Fujihara, Sho}, title = {New horizontal inequalities in Japanese education?}, series = {Research in Social Stratification and Mobility}, volume = {81}, journal = {Research in Social Stratification and Mobility}, publisher = {Elsevier}, address = {Oxford}, issn = {0276-5624}, doi = {10.1016/j.rssm.2022.100727}, pages = {14}, year = {2022}, abstract = {The literature on social inequality in study abroad almost exclusively focuses on university students. This paper systematically examines the role of socioeconomic status (SES) for study abroad intent (SAI) and uptake across all levels of pre-college education in Japan, thereby also providing a first in-depth empirical study on pre-college study abroad (PSA) in this country. Drawing on theories of social inequality (especially the effectively main-tained inequality (EMI) thesis) in combination with elements from cumulative advantage and life course research, we understand the intention and final decision to study abroad as an outcome of SES-specific differ-ences in educational biographies, with higher SES families seeking transnational education for their children to achieve status advantages. Using large-scale cross-sectional data for Japan (N = 15,450) for children aged three to eighteen years, binary and generalized ordered logit regressions show that children from high SES families are generally more likely to (1) express SAI (especially for college) and take up PSA; and (2) choose more exclusive forms of PSA, i.e. earlier and more lengthy stays. Findings further indicate that (3) the SES-gap in the likelihood to show SAI or take up PSA is highest at the pre-and high school levels. Applying the KHB method we found that (4) the percentage of SES effects on SAI mediated through earlier PSA experience is marginal or even reversed at times. We conclude that early PSA experience is positively related to further SAI, with high SES students likely accumulating transnational human capital to a greater extent, possibly acquiring status advantages. In sum, our results support the EMI and cumulative advantage perspectives, indicating undetected first-and second-level horizontal inequalities in Japanese education and call for similar research in other national contexts.}, language = {en} } @article{Metzger2023, author = {Metzger, Jan}, title = {Refined position estimates for surfaces of Willmore type in Riemannian manifolds}, series = {Communications in analysis and geometry}, volume = {30}, journal = {Communications in analysis and geometry}, number = {10}, publisher = {International Press of Boston}, address = {Somerville, Mass.}, issn = {1019-8385}, doi = {10.4310/CAG.2022.v30.n10.a5}, pages = {2315 -- 2346}, year = {2023}, abstract = {In this paper we consider surfaces which are critical points of the Willmore functional subject to constrained area. In the case of small area we calculate the corrections to the intrinsic geometry induced by the ambient curvature. These estimates together with the choice of an adapted geometric center of mass lead to refined position estimates in relation to the scalar curvature of the ambient manifold.}, language = {en} } @article{PfeiferBeierAlirezaeizanjanietal.2022, author = {Pfeifer, Veronika and Beier, S{\"o}nke and Alirezaeizanjani, Zahra and Beta, Carsten}, title = {Role of the two flagellar stators in swimming motility of pseudomonas putida}, series = {mBio}, volume = {13}, journal = {mBio}, number = {6}, publisher = {American Society for Microbiology}, address = {Washington}, issn = {2150-7511}, doi = {10.1128/mbio.02182-22}, pages = {12}, year = {2022}, abstract = {In the soil bacterium Pseudomonas putida, the motor torque for flagellar rotation is generated by the two stators MotAB and MotCD. Here, we construct mutant strains in which one or both stators are knocked out and investigate their swimming motility in fluids of different viscosity and in heterogeneous structured environments (semisolid agar). Besides phase-contrast imaging of single-cell trajectories and spreading cultures, dual-color fluorescence microscopy allows us to quantify the role of the stators in enabling P. putida's three different swimming modes, where the flagellar bundle pushes, pulls, or wraps around the cell body. The MotAB stator is essential for swimming motility in liquids, while spreading in semisolid agar is not affected. Moreover, if the MotAB stator is knocked out, wrapped mode formation under low-viscosity conditions is strongly impaired and only partly restored for increased viscosity and in semisolid agar. In contrast, when the MotCD stator is missing, cells are indistinguishable from the wild type in fluid experiments but spread much more slowly in semisolid agar. Analysis of the microscopic trajectories reveals that the MotCD knockout strain forms sessile clusters, thereby reducing the number of motile cells, while the swimming speed is unaffected. Together, both stators ensure a robust wild type that swims efficiently under different environmental conditions. IMPORTANCE Because of its heterogeneous habitat, the soil bacterium Pseudomonas putida needs to swim efficiently under very different environmental conditions. In this paper, we knocked out the stators MotAB and MotCD to investigate their impact on the swimming motility of P. putida. While the MotAB stator is crucial for swimming in fluids, in semisolid agar, both stators are sufficient to sustain a fast-swimming phenotype and increased frequencies of the wrapped mode, which is known to be beneficial for escaping mechanical traps. However, in contrast to the MotAB knockout, a culture of MotCD knockout cells spreads much more slowly in the agar, as it forms nonmotile clusters that reduce the number of motile cells. Because of its heterogeneous habitat, the soil bacterium Pseudomonas putida needs to swim efficiently under very different environmental conditions. In this paper, we knocked out the stators MotAB and MotCD to investigate their impact on the swimming motility of P. putida.}, language = {en} } @article{AmorosoHerrmannKritikos2024, author = {Amoroso, Sara and Herrmann, Benedikt and Kritikos, Alexander S.}, title = {The role of regulation and regional government quality for high-growth firms}, series = {Regional studies}, journal = {Regional studies}, publisher = {Taylor \& Francis}, address = {London}, issn = {0034-3404}, doi = {10.1080/00343404.2024.2366289}, pages = {1 -- 18}, year = {2024}, abstract = {High-growth firms (HGFs) are important for job creation and productivity growth. We investigate the relationship between product and labour market regulations, as well as the quality of regional governments that implement these regulations, and the development of HGFs across European regions. Using data from Eurostat, the Organisation for Economic Co-operation and Development (OECD), World Economic Forum (WEF), and Gothenburg University, we show that both regulatory stringency and the quality of the regional government relate to the regional shares of HGFs. In particular, we find that the effect of labour and product market regulations is moderated by the quality of regional government. Depending on the quality of regional governments, regulations may have a 'good, bad or ugly' influence on the development of HGFs. Our findings contribute to the debate on the effects of regulations and offer important building blocks to develop tailored policy measures that may influence the development of HGFs in a region.}, language = {en} } @article{HanischLudewig2022, author = {Hanisch, Florian and Ludewig, Matthias}, title = {The fermionic integral on loop space and the Pfaffian line bundle}, series = {Journal of mathematical physics}, volume = {63}, journal = {Journal of mathematical physics}, number = {12}, publisher = {American Inst. of Physics}, address = {College Park, Md.}, issn = {0022-2488}, doi = {10.1063/5.0060355}, pages = {26}, year = {2022}, abstract = {As the loop space of a Riemannian manifold is infinite-dimensional, it is a non-trivial problem to make sense of the "top degree component " of a differential form on it. In this paper, we show that a formula from finite dimensions generalizes to assign a sensible "top degree component " to certain composite forms, obtained by wedging with the exponential (in the exterior algebra) of the canonical presymplectic 2-form on the loop space. This construction is a crucial ingredient for the definition of the supersymmetric path integral on the loop space.}, language = {en} } @article{ContierWeymarWartenburgeretal.2022, author = {Contier, Friederike and Weymar, Mathias and Wartenburger, Isabell and Rabovsky, Milena}, title = {Sustained attention as measured by reaction time variability is a strong modulator for the P600, but not the N400}, series = {Journal of cognitive neuroscience}, volume = {34}, journal = {Journal of cognitive neuroscience}, number = {12}, publisher = {MIT Press}, address = {Cambridge}, issn = {0898-929X}, doi = {10.1162/jocn_a_01918}, pages = {2297 -- 2310}, year = {2022}, abstract = {The functional significance of the two prominent language-related ERP components N400 and P600 is still under debate. It has recently been suggested that one important dimension along which the two vary is in terms of automaticity versus attentional control, with N400 amplitudes reflecting more automatic and P600 amplitudes reflecting more controlled aspects of sentence comprehension. The availability of executive resources necessary for controlled processes depends on sustained attention, which fluctuates over time. Here, we thus tested whether P600 and N400 amplitudes depend on the level of sustained attention. We reanalyzed EEG and behavioral data from a sentence processing task by Sassenhagen and Bornkessel-Schlesewsky [The P600 as a correlate of ventral attention network reorientation. Cortex, 66, A3-A20, 2015], which included sentences with morphosyntactic and semantic violations. Participants read sentences phrase by phrase and indicated whether a sentence contained any type of anomaly as soon as they had the relevant information. To quantify the varying degrees of sustained attention, we extracted a moving reaction time coefficient of variation over the entire course of the task. We found that the P600 amplitude was significantly larger during periods of low reaction time variability (high sustained attention) than in periods of high reaction time variability (low sustained attention). In contrast, the amplitude of the N400 was not affected by reaction time variability. These results thus suggest that the P600 component is sensitive to sustained attention whereas the N400 component is not, which provides independent evidence for accounts suggesting that P600 amplitudes reflect more controlled and N400 amplitudes reflect more automatic aspects of sentence comprehension.}, language = {en} } @inproceedings{Brinkmann2021, author = {Brinkmann, Maik}, title = {Relevance of public administrations}, series = {Proceedings of the 54th Hawaii International Conference on System Sciences 2021}, booktitle = {Proceedings of the 54th Hawaii International Conference on System Sciences 2021}, publisher = {University of Hawaiʻi at Mānoa}, address = {Honolulu, HI}, isbn = {978-0-9981331-4-0}, doi = {10.24251/HICSS.2021.285}, pages = {10}, year = {2021}, abstract = {Power relations within the area of blockchain governance are complex by definition and a comprehensive analysis that links technological and institutional elements is missing to date. The research that is presented with this article focuses on the visualization of the shifting power relations with the introduction of blockchain. For this purpose, the analysis leverages an adjusted version of the multi-stakeholder influence mapping tool. The analysis considers the various stakeholders within the multi-layered blockchain technology stack and compares three fundamental blockchain scenarios, including public and private blockchain settings. The findings show that public administrations face indeed less power with the introduction of blockchain, while new stakeholders come into play who wield influence rather uncontrolled. Nonetheless, public administrations are not powerless overall and remain influential stakeholders. This paper concludes that blockchain governance is not as democratic as blockchain enthusiasts tend to argue and derives corresponding opportunities for further research.}, language = {en} } @article{BannisterBertrandHeimannetal.2022, author = {Bannister, Stephen and Bertrand, Edward A. and Heimann, Sebastian and Bourguignon, Sandra and Asher, Cameron and Shanks, Jackson and Harvison, Adrian}, title = {Imaging sub-caldera structure with local seismicity, Okataina Volcanic Centre, Taupo Volcanic Zone, using double-difference seismic tomography}, series = {Journal of volcanology and geothermal research}, volume = {431}, journal = {Journal of volcanology and geothermal research}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0377-0273}, doi = {10.1016/j.jvolgeores.2022.107653}, pages = {16}, year = {2022}, abstract = {We examine sub-caldera structure and seismicity in and around the Okataina Volcanic Centre (OVC), Taupo Volcanic Zone, New Zealand, using seismic data collected over 4+ years with a temporary array of broadband and short-period seismometers, supplementing data from the permanent New Zealand seismometer network. We derive a new 3-D image of P-wave seismic velocity for the upper crust in the region, using double-difference seismic tomography and utilising waveform cross-correlations. We subsequently relocate 6989 earthquakes which occurred in the region over the 2010-2021 time period, using the 3D velocity model. The seismicity distribution shows spatial clusters west of Lake Rotomahana, as well as beneath Haroharo and the Makatiti Dome, inside the Okataina caldera. Beneath Makatiti Dome 90\% of the events are shallower than 7.7 +/- 0.5 km. Outside of the Okataina caldera event relocations highlight short (similar to 3-4 km long) streaks of activity in the Ngakuru graben, part of the active Taupo Rift southwest of Okataina caldera. Inside the OVC the relocated seismicity beneath Makatiti appears closely associated with low (similar to 10\%) P-wave velocity anomalies, which we resolve in the similar to 5-to-8-km depth range beneath the Okataina caldera, and which are likely related to partial melt and/or fluid-volatile pathways. Moment tensor analyses for two larger-magnitude events (M(L)4.5 and M(L)4.9) near Haroharo indicate normal faulting, with NNE-SSW fault strike, but with positive CLVD and positive isotropic components when allowing for a full moment tensor, consistent with a magmatic environment with degassing and/or fluid migration.}, language = {en} } @article{ClausenStede2022, author = {Clausen, Yulia and Stede, Manfred}, title = {Discourse connectives and their arguments}, series = {Linguistics Vanguard}, volume = {8}, journal = {Linguistics Vanguard}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, issn = {2199-174X}, doi = {10.1515/lingvan-2021-0102}, pages = {95 -- 111}, year = {2022}, abstract = {Adverbial connectives like therefore, which link a preceding 'external' to an 'internal' argument, can be regarded as anaphoric: The external argument is selected by an interpretation process akin to that of an event anaphor, and intervening material can appear between both arguments. We report on a crowdsourcing experiment on the German connectives trotzdem and dennoch that studies factors that lead readers to assume such long-distance arguments: semantic plausibility of intervening material, 'subjective' versus 'objective' content, and the presence of an anaphoric morpheme in the connective. We find that the type and content of the intervening material play an important role in argument choice.}, language = {en} } @article{SchrothFlindt2020, author = {Schroth, Johannes and Flindt, Jan Ole}, title = {Aktenvortrag - Zivilrecht}, series = {Juristische Schulung}, volume = {60}, journal = {Juristische Schulung}, number = {6}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {0022-6939}, pages = {555 -- 560}, year = {2020}, abstract = {In materieller Hinsicht ist in diesem Aktenvortrag der praxisgerechte Umgang mit dem Deliktsrecht und dem zivilrechtlichen Nachbarrecht zu bewerkstelligen. Prozessual bietet der Sachverhalt M{\"o}glichkeit zur Bearbeitung examensklassischer Problemkreise. Es handelt sich um eine sehr umfangreiche Aufgabe. Um die vorgegebene Bearbeitungszeit einzuhalten, kann der Vortrag kaum in allen Punkten so ausf{\"u}hrlich gehalten werden wie die hier vorgeschlagene L{\"o}sung. Das wird aber f{\"u}r eine gute Bewertung auch nicht erforderlich sein. Vielmehr kommt es, wie stets, auf eine {\"u}berzeugende Schwerpunktsetzung an.}, language = {de} } @article{TanKhaliliKarletal.2022, author = {Tan, Jing and Khalili, Ramin and Karl, Holger and Hecker, Artur}, title = {Multi-agent reinforcement learning for long-term network resource allocation through auction: a V2X application}, series = {Computer communications : the international journal for the computer and telecommunications industry}, volume = {194}, journal = {Computer communications : the international journal for the computer and telecommunications industry}, publisher = {Elsevier Science}, address = {Amsterdam [u.a.]}, issn = {0140-3664}, doi = {10.1016/j.comcom.2022.07.047}, pages = {333 -- 347}, year = {2022}, abstract = {We formulate offloading of computational tasks from a dynamic group of mobile agents (e.g., cars) as decentral-ized decision making among autonomous agents. We design an interaction mechanism that incentivizes such agents to align private and system goals by balancing between competition and cooperation. In the static case, the mechanism provably has Nash equilibria with optimal resource allocation. In a dynamic environment, this mechanism's requirement of complete information is impossible to achieve. For such environments, we propose a novel multi-agent online learning algorithm that learns with partial, delayed and noisy state information, thus greatly reducing information need. Our algorithm is also capable of learning from long-term and sparse reward signals with varying delay. Empirical results from the simulation of a V2X application confirm that through learning, agents with the learning algorithm significantly improve both system and individual performance, reducing up to 30\% of offloading failure rate, communication overhead and load variation, increasing computation resource utilization and fairness. Results also confirm the algorithm's good convergence and generalization property in different environments.}, language = {en} } @article{HermannsKunold2022, author = {Hermanns, Jolanda and Kunold, Helen}, title = {Mechanism comics as a task in a written exam in organic chemistry for pre-service chemistry teachers}, series = {Chemistry teacher international : best practices in chemistry education}, volume = {4}, journal = {Chemistry teacher international : best practices in chemistry education}, number = {3}, publisher = {De Gruyter}, address = {Berlin}, issn = {2569-3263}, doi = {10.1515/cti-2021-0035}, pages = {259 -- 269}, year = {2022}, abstract = {In this paper, we describe and evaluate a study on the use of mechanism comics for writing solutions to a task in a written exam for the course "Organic Chemistry I for Pre-Service Chemistry Teachers." The students had to design a reaction mechanism for a reaction that was unknown to them and write captions explaining every step of their reaction mechanism. The students' work was evaluated using the method of qualitative content analysis in four rounds by both authors. The majority of the captions were coded as "descriptive" and only a minority as "causal." This means that the students mostly described "what" happened, but seldom "why" this happened. Implicit electron movement was also described more often than explicit electron movement. The majority of the captions were technically correct. In summary, the students were capable of designing and describing a reaction mechanism for a previously unknown reaction. The quality of their reasoning could be improved, however. In the new course, the quality of students' mechanistic reasoning and then especially their explanations of "why" mechanistic steps occur will be given much clearer emphasis.}, language = {en} } @article{Flindt2020, author = {Flindt, Jan Ole}, title = {Das beschleunigte Familiengericht}, series = {Zeitschrift f{\"u}r das gesamte Verfahrensrecht}, volume = {3}, journal = {Zeitschrift f{\"u}r das gesamte Verfahrensrecht}, number = {2}, publisher = {Otto Schmidt}, address = {K{\"o}ln}, issn = {2625-1868}, doi = {10.9785/gvrz-2020-030203}, pages = {13 -- 13}, year = {2020}, abstract = {Gegenstand des Beitrags ist schwerpunktm{\"a}ßig das im Jahr 2016 mit den \S\S 155b , 155c FamFG geschaffene Rechtsbehelfssystem der Beschleunigungsr{\"u}ge und Beschleunigungsbeschwerde. Bevor Grund und Grenze der Verfahrensbeschleunigung in Kindschaftssachen unter besonderer Ber{\"u}cksichtigung des Gedankens der Verfahrens{\"o}konomie ausgelotet werden, geht der Verfasser auf das Verh{\"a}ltnis zwischen Beschleunigungsgrundsatz und Prozess{\"o}konomie in gebotener K{\"u}rze ein. Anschließend liegt der Fokus auf dem Beschleunigungsgrundsatz; zun{\"a}chst in familiengerichtlichen Verfahren im Allgemeinen und sodann im kindschaftsrechtlichen Verfahren im Speziellen. In Bezug auf Letzteres wird ferner aufzuzeigen sein, dass Verfahrens{\"o}konomie die kindeswohldienliche Anwendung des Beschleunigungsgrundsatzes bedeutet. Dieser Anwendungsbefehl soll abschließend am Beispiel des einleitend angesprochenen, relativ neuen Rechtsbehelfsverfahrens exemplifiziert werden, um der Frage nachzugehen, ob das Kindschaftsverfahrensrecht mehr Effektivit{\"a}t vertr{\"a}gt.}, language = {de} } @book{Flindt2022, author = {Flindt, Jan Ole}, title = {Gutgl{\"a}ubig gelebte Statusverh{\"a}ltnisse}, series = {Studien zum Privatrecht}, volume = {109}, journal = {Studien zum Privatrecht}, publisher = {Mohr Siebeck}, address = {T{\"u}bingen}, isbn = {978-3-16-161843-7}, doi = {10.1628/978-3-16-161843-7}, pages = {XV, 406}, year = {2022}, abstract = {Jan Ole Flindt befasst sich mit Fallkonstellationen, in denen ein rechtlich unzutreffender Name tats{\"a}chlich gef{\"u}hrt oder eine unwirksame Ehe oder ein rechtlich nicht bestehendes Eltern-Kind-Verh{\"a}ltnis wirklich gelebt wird. Im Mittelpunkt der Untersuchung steht die Frage nach Bestand und Reichweite von Vertrauensschutz im deutschen statusorientierten Recht. Statusrecht und Vertrauensschutzgedanke werden zun{\"a}chst grundlegend beleuchtet, bevor der Autor das einschl{\"a}gige Fallmaterial systematisch aufbereitet und punktuell bestehende L{\"o}sungsans{\"a}tze des geltenden Rechts zusammentr{\"a}gt. Letztere reichen von einer statusrechtlichen Heilung {\"u}ber einen (partiellen) schuldrechtlichen Ausgleich bis hin zu einer Versagung jeglichen Vertrauensschutzes. Die Dekonstruktion der L{\"o}sungsans{\"a}tze offenbart status{\"u}bergreifende Gemeinsamkeiten, aber auch methodische Schw{\"a}chen und unbillige Ergebnisse im Einzelfall. Dies nimmt Jan Ole Flindt zum Anlass, einen status{\"u}bergreifenden Heilungsansatz im Sinne einer allgemeinen Statusersitzung zur Diskussion zu stellen.}, language = {de} } @article{SandauGranacher2022, author = {Sandau, Ingo and Granacher, Urs}, title = {Long-term monitoring of training load, force-velocity profile, and Performance in elite weightlifters: a case series with two male Olympic athletes}, series = {Journal of strength and conditioning research : the research journal of the NSCA}, volume = {36}, journal = {Journal of strength and conditioning research : the research journal of the NSCA}, number = {12}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia, Pa.}, issn = {1064-8011}, doi = {10.1519/JSC.0000000000004228}, pages = {3446 -- 3455}, year = {2022}, abstract = {The aim of this case series approach was to analyze weekly changes in force-velocity relationship (FvR) parameters ((v) over bar, (F) over bar (0), (P) over bar (max)) and theoretical snatch performance (snatchth) assessed through a specific snatch pull test in preparation of the European and World Championships in 2 male elite weightlifters. A second aim was to examine associations of training load (volume, volume load, average load), barbell -, and snatchth over a period of 2 macrocycles in preparation of the same competitions. FvR-parameters, snatchth, training load data, and body mass were assessed weekly over 40 weeks. Using the smallest real difference approach, significant (p <= 0.05) decreases in (v) over bar (0) and increases in (v) over bar, (F) over bar (0), (P) over bar (max), and snatchth were found within macrocycles. However, the large significant loss in body mass (approximate to 11\%) in athlete 1 during macrocycle 2 represents most likely a main factor for diminished (P) over bar (max), and snatchth in macrocycle 2. Based on cross-correlation analyses, barbell FvR-parameters and snatchth were significantly (p <= 0.05) associated with maximal strength, muscle power, and speed training load variables. Moderate correlations (0.31-0.47) were found between training load and (P) over bar (max) and snatchth in athlete 2. It can be concluded that the applied training loads elicits improvements in <(P)(max) and snatchth because the athlete approached the main competitions. However, because of the large loss in body mass, the relations between training load and barbell FvR-parameters and snatchth were less clear in athlete 1. It seems that a loss in body mass as a result of a change in bodyweight category mitigates <(P)over bar>(max) development during the macrocycle and hindered to reach peak snatchth at the main competitions.}, language = {en} } @article{Russell2022, author = {Russell, Eric-John}, title = {Nada es ya lo contrario de nada : la sociedad del espect{\´a}culo de Guy Debord hoy}, series = {Constelaciones : Revista de Teor{\´i}a Cr{\´i}tica}, volume = {14}, journal = {Constelaciones : Revista de Teor{\´i}a Cr{\´i}tica}, publisher = {Departament de Filosof{\´i}a, Universitat de les Illes Balears}, address = {Palma, Spanien}, issn = {2172-9506}, pages = {426 -- 434}, year = {2022}, language = {es} } @misc{Reimann2024, type = {Master Thesis}, author = {Reimann, Hans}, title = {Towards robust inference for Bayesian filtering of linear Gaussian dynamical systems subject to additive change}, doi = {10.25932/publishup-64946}, url = {http://nbn-resolving.de/urn:nbn:de:kobv:517-opus4-649469}, school = {Universit{\"a}t Potsdam}, pages = {ix, 156}, year = {2024}, abstract = {State space models enjoy wide popularity in mathematical and statistical modelling across disciplines and research fields. Frequent solutions to problems of estimation and forecasting of a latent signal such as the celebrated Kalman filter hereby rely on a set of strong assumptions such as linearity of system dynamics and Gaussianity of noise terms. We investigate fallacy in mis-specification of the noise terms, that is signal noise and observation noise, regarding heavy tailedness in that the true dynamic frequently produces observation outliers or abrupt jumps of the signal state due to realizations of these heavy tails not considered by the model. We propose a formalisation of observation noise mis-specification in terms of Huber's ε-contamination as well as a computationally cheap solution via generalised Bayesian posteriors with a diffusion Stein divergence loss resulting in the diffusion score matching Kalman filter - a modified algorithm akin in complexity to the regular Kalman filter. For this new filter interpretations of novel terms, stability and an ensemble variant are discussed. Regarding signal noise mis-specification, we propose a formalisation in the frame work of change point detection and join ideas from the popular CUSUM algo- rithm with ideas from Bayesian online change point detection to combine frequent reliability constraints and online inference resulting in a Gaussian mixture model variant of multiple Kalman filters. We hereby exploit open-end sequential probability ratio tests on the evidence of Kalman filters on observation sub-sequences for aggregated inference under notions of plausibility. Both proposed methods are combined to investigate the double mis-specification problem and discussed regarding their capabilities in reliable and well-tuned uncertainty quantification. Each section provides an introduction to required terminology and tools as well as simulation experiments on the popular target tracking task and the non-linear, chaotic Lorenz-63 system to showcase practical performance of theoretical considerations.}, language = {en} } @misc{Krasnova2023, author = {Krasnova, Hanna}, title = {Interview with Christoph Neuberger on "How digital technologies are shaping our society and what we can do about it"}, series = {Business \& information systems engineering}, volume = {65}, journal = {Business \& information systems engineering}, number = {5}, publisher = {Springer Fachmedien}, address = {Wiesbaden}, issn = {2363-7005}, doi = {10.1007/s12599-023-00832-9}, pages = {609 -- 611}, year = {2023}, language = {en} }