@article{GriessnerHartigChristmannetal.2010, author = {Grießner, Matthias and Hartig, Dave and Christmann, Alexander and Ehrentreich-F{\"o}rster, Eva and Warsinke, Axel and Bier, Frank Fabian}, title = {Surface regeneration of microfluidic microarray printheads through plasma techniques}, issn = {0960-1317}, doi = {10.1088/0960-1317/20/3/037002}, year = {2010}, abstract = {This work describes a method for surface regeneration of microfluidic microarray printheads through plasma techniques. Modification procedures were chosen in a way to obtain high reproducibility with a minimum of time consumption. The idea behind this is a complete regeneration of a microarray printhead before or after usage to achieve best printing results over a typical print job. A sequence of low-pressure oxygen-plasma and plasma polymerization with hexamethyldisiloxane (HMDSO) was used to regenerate printheads. Proof of the concept is given through quality control performed with a spotter implemented CCD camera, contact angle measurements and a typical hybridization experiment. Stable printing results were obtained over 3000 activations showing that the presented method is suitable for treatment of microarray printheads.}, language = {en} }