Refine
Year of publication
Document Type
- Article (35163)
- Doctoral Thesis (6463)
- Monograph/Edited Volume (5516)
- Postprint (3253)
- Review (2280)
- Part of a Book (993)
- Other (870)
- Preprint (566)
- Conference Proceeding (528)
- Part of Periodical (450)
Language
Keywords
- Germany (198)
- climate change (171)
- Deutschland (138)
- European Union (78)
- Sprachtherapie (77)
- machine learning (75)
- diffusion (74)
- Patholinguistik (73)
- morphology (73)
- patholinguistics (73)
Institute
- Institut für Biochemie und Biologie (5359)
- Institut für Physik und Astronomie (5319)
- Institut für Geowissenschaften (3543)
- Institut für Chemie (3440)
- Wirtschaftswissenschaften (2636)
- Historisches Institut (2482)
- Department Psychologie (2319)
- Institut für Mathematik (2130)
- Institut für Romanistik (2105)
- Sozialwissenschaften (1882)
- Extern (1571)
- Institut für Umweltwissenschaften und Geographie (1539)
- Department Sport- und Gesundheitswissenschaften (1467)
- Department Erziehungswissenschaft (1458)
- Institut für Germanistik (1432)
- Department Linguistik (1371)
- Bürgerliches Recht (1330)
- Institut für Ernährungswissenschaft (1242)
- Institut für Jüdische Studien und Religionswissenschaft (1132)
- MenschenRechtsZentrum (1128)
- Öffentliches Recht (1123)
- Institut für Informatik und Computational Science (1102)
- Institut für Anglistik und Amerikanistik (763)
- WeltTrends e.V. Potsdam (659)
- Department Grundschulpädagogik (632)
- Institut für Slavistik (586)
- Philosophische Fakultät (563)
- Mathematisch-Naturwissenschaftliche Fakultät (542)
- Strafrecht (471)
- Vereinigung für Jüdische Studien e. V. (455)
- Strukturbereich Kognitionswissenschaften (424)
- Hasso-Plattner-Institut für Digital Engineering gGmbH (402)
- Hasso-Plattner-Institut für Digital Engineering GmbH (398)
- Institut für Künste und Medien (386)
- Fachgruppe Betriebswirtschaftslehre (348)
- Fachgruppe Politik- & Verwaltungswissenschaft (336)
- Lehreinheit für Wirtschafts-Arbeit-Technik (306)
- Humanwissenschaftliche Fakultät (292)
- Department für Inklusionspädagogik (289)
- Zentrum für Lehrerbildung und Bildungsforschung (ZeLB) (245)
- Department Musik und Kunst (241)
- Kommunalwissenschaftliches Institut (222)
- Fachgruppe Volkswirtschaftslehre (185)
- Institut für Philosophie (181)
- Zentrum für Umweltwissenschaften (165)
- Wirtschafts- und Sozialwissenschaftliche Fakultät (161)
- Fachgruppe Soziologie (146)
- Referat für Presse- und Öffentlichkeitsarbeit (138)
- Klassische Philologie (121)
- Interdisziplinäres Zentrum für Dynamik komplexer Systeme (120)
- Strukturbereich Bildungswissenschaften (114)
- Institut für Jüdische Theologie (95)
- Arbeitskreis Militär und Gesellschaft in der Frühen Neuzeit e. V. (92)
- Verband für Patholinguistik e. V. (vpl) (87)
- Zentrum für Gerechtigkeitsforschung (87)
- Zentrum für Sprachen und Schlüsselkompetenzen (Zessko) (79)
- Center for Economic Policy Analysis (CEPA) (75)
- An-Institute (72)
- Fakultät für Gesundheitswissenschaften (72)
- Institut für Religionswissenschaft (64)
- Universitätsbibliothek (60)
- Zentrum für Qualitätsentwicklung in Lehre und Studium (ZfQ) (57)
- ZIM - Zentrum für Informationstechnologie und Medienmanagement (49)
- Berlin Potsdam Research Group "The International Rule of Law - Rise or Decline?" (46)
- Juristische Fakultät (34)
- Moses Mendelssohn Zentrum für europäisch-jüdische Studien e. V. (34)
- Universitätsleitung und Verwaltung (34)
- dbs Deutscher Bundesverband für akademische Sprachtherapie und Logopädie e.V. (31)
- Zentrum für Lern- und Lehrforschung (30)
- Institut für Lebensgestaltung-Ethik-Religionskunde (27)
- Interdisziplinäres Zentrum für Dünne Organische und Biochemische Schichten (26)
- Sonderforschungsbereich 632 - Informationsstruktur (25)
- Interdisziplinäres Zentrum für Musterdynamik und Angewandte Fernerkundung (23)
- Potsdam Research Institute for Multilingualism (PRIM) (18)
- Dezernat 2: Studienangelegenheiten (16)
- Hochschulambulanz (15)
- Potsdam Transfer - Zentrum für Gründung, Innovation, Wissens- und Technologietransfer (15)
- Interdisziplinäres Zentrum für Biopolymere (12)
- Potsdam Institute for Climate Impact Research (PIK) e. V. (12)
- Organe und Gremien (11)
- Digital Engineering Fakultät (10)
- Institut für angewandte Familien-, Kindheits- und Jugendforschung e.V. (10)
- Präsident | Vizepräsidenten (9)
- Deutsches MEGA-Konsortialbüro an der Universität Potsdam (8)
- Abraham Geiger Kolleg gGmbH (7)
- Netzwerk Studienqualität Brandenburg (sqb) (7)
- Multilingualism (6)
- Patholinguistics/Neurocognition of Language (6)
- Theodor-Fontane-Archiv (6)
- Zentrum für Australienforschung (6)
- Gleichstellungsbeauftragte (5)
- Interdisziplinäres Zentrum für Kognitive Studien (5)
- Senat (5)
- Forschungsbereich „Politik, Verwaltung und Management“ (4)
- Kanonistisches Institut e.V. (4)
- Psycholinguistics and Neurolinguistics (4)
- Akademie für Psychotherapie und Interventionsforschung GmbH (3)
- Gesundheitsmanagement (3)
- Kanzler (3)
- UP Transfer (3)
- eLiS - E-Learning in Studienbereichen (3)
- DV und Statistik Wirtschaftswissenschaften (2)
- Kommissionen des Senats (2)
- Language Acquisition (2)
- Projekte (2)
- Zentrale und wissenschaftliche Einrichtungen (2)
- Allgemeine Studierendenausschuss (AStA) (1)
- Applied Computational Linguistics (1)
- Botanischer Garten (1)
- Career Service (1)
- Chief Information Officer (CIO) (1)
- Evangelisches Institut für Kirchenrecht e.V. (1)
- Foundations of Computational Linguistics (1)
- Geschlechtersoziologie (1)
- Interdisziplinäres Zentrum für Massenspektronomie von Biopolymeren (1)
- Phonology & Phonetics (1)
- Potsdam Graduate School (1)
- Präsidialamt (1)
- Redaktion *studere (1)
- Studierendenparlament (StuPa) (1)
- Syntax, Morphology & Variability (1)
- Weitere Einrichtungen (1)
How biased are our models?
(2021)
Geophysical process simulations play a crucial role in the understanding of the subsurface. This understanding is required to provide, for instance, clean energy sources such as geothermal energy. However, the calibration and validation of the physical models heavily rely on state measurements such as temperature. In this work, we demonstrate that focusing analyses purely on measurements introduces a high bias. This is illustrated through global sensitivity studies. The extensive exploration of the parameter space becomes feasible through the construction of suitable surrogate models via the reduced basis method, where the bias is found to result from very unequal data distribution. We propose schemes to compensate for parts of this bias. However, the bias cannot be entirely compensated. Therefore, we demonstrate the consequences of this bias with the example of a model calibration.
Urban air pollution is a substantial threat to human health. Traffic emissions remain a large contributor to air pollution in urban areas. The mobility restrictions put in place in response to the COVID-19 pandemic provided a large-scale real-world experiment that allows for the evaluation of changes in traffic emissions and the corresponding changes in air quality. Here we use observational data, as well as modelling, to analyse changes in nitrogen dioxide, ozone, and particulate matter resulting from the COVID-19 restrictions at the height of the lockdown period in Spring of 2020. Accounting for the influence of meteorology on air quality, we found that reduction of ca. 30-50 % in traffic counts, dominated by changes in passenger cars, corresponded to reductions in median observed nitrogen dioxide concentrations of ca. 40 % (traffic and urban background locations) and a ca. 22 % increase in ozone (urban background locations) during weekdays. Lesser reductions in nitrogen dioxide concentrations were observed at urban background stations at weekends, and no change in ozone was observed. The modelled reductions in median nitrogen dioxide at urban background locations were smaller than the observed reductions and the change was not significant. The model results showed no significant change in ozone on weekdays or weekends. The lack of a simulated weekday/weekend effect is consistent with previous work suggesting that NOx emissions from traffic could be significantly underestimated in European cities by models. These results indicate the potential for improvements in air quality due to policies for reducing traffic, along with the scale of reductions that would be needed to result in meaningful changes in air quality if a transition to sustainable mobility is to be seriously considered. They also confirm once more the highly relevant role of traffic for air quality in urban areas.
The understanding of bidimensional materials dynamics and its electrolyte interface equilibrium, such as graphene oxide (GO), is critical for the development of a capacitive biosensing platform. The interfacial capacitance (C-i) of graphene-based materials may be tuned by experimental conditions such as pH optimization and cation size playing key roles at the enhancement of their capacitive properties allowing their application as novel capacitive biosensors. Here we reported a systematic study of C-i of multilayer GO films in different aqueous electrolytes employing electrochemical impedance spectroscopy for the application in a capacitive detection system. We demonstrated that the presence of ionizable oxygen-containing functional groups within multilayer GO film favors the interactions and the accumulation of cations in the structure of the electrodes enhancing the GO C-i in aqueous solutions, where at pH 7.0 (the best condition) the C-i was 340 mu F mg(-1) at -0.01 V vs Ag/AgCl. We also established that the hydrated cation radius affects the mobility and interaction with GO functional groups and it plays a critical role in the Ci, as demonstrated in the presence of different cations Na+=640 mu F mg(-1), Li+=575 mu F mg(-1) and TMA(+)=477 mu F mg(-1). As a proof-of-concept, the capacitive behaviour of GO was explored as biosensing platform for standard streptavidin-biotin systems. For this system, the C-i varied linearly with the log of the concentration of the targeting analyte in the range from 10 pg mL(-1) to 100 ng mL(-1), showing the promising applicability of capacitive GO based sensors for label-free biosensing.
Design thinking is a well-established practical and educational approach to fostering high-level creativity and innovation, which has been refined since the 1950s with the participation of experts like Joy Paul Guilford and Abraham Maslow. Through real-world projects, trainees learn to optimize their creative outcomes by developing and practicing creative cognition and metacognition. This paper provides a holistic perspective on creativity, enabling the formulation of a comprehensive theoretical framework of creative metacognition. It focuses on the design thinking approach to creativity and explores the role of metacognition in four areas of creativity expertise: Products, Processes, People, and Places. The analysis includes task-outcome relationships (product metacognition), the monitoring of strategy effectiveness (process metacognition), an understanding of individual or group strengths and weaknesses (people metacognition), and an examination of the mutual impact between environments and creativity (place metacognition). It also reviews measures taken in design thinking education, including a distribution of cognition and metacognition, to support students in their development of creative mastery. On these grounds, we propose extended methods for measuring creative metacognition with the goal of enhancing comprehensive assessments of the phenomenon. Proposed methodological advancements include accuracy sub-scales, experimental tasks where examinees explore problem and solution spaces, combinations of naturalistic observations with capability testing, as well as physiological assessments as indirect measures of creative metacognition.
Case report
(2023)
The increasing prevalence of Long COVID is an imminent public health disaster, and established approaches have not provided adequate diagnostics or treatments. Recently, anesthetic blockade of the stellate ganglion was reported to improve Long COVID symptoms in a small case series, purportedly by "rebooting" the autonomic nervous system. Here, we present a novel diagnostic approach based on the Adaptive Force (AF), and report sustained positive outcome for one severely affected Long COVID patient using individualized pulsed electromagnetic field (PEMF) at the area C7/T1. AF reflects the capacity of the neuromuscular system to adapt adequately to external forces in an isometric holding manner. In case, maximal isometric AF (AFiso(max)) is exceeded, the muscle merges into eccentric muscle action. Thereby, the force usually increases further until maximal AF (AFmax) is reached. In case adaptation is optimal, AFiso(max) is similar to 99-100% of AFmax. This holding capacity (AFiso(max)) was found to be vulnerable to disruption by unpleasant stimulus and, hence, was regarded as functional parameter. AF was assessed by an objectified manual muscle test using a handheld device. Prior to treatment, AFiso(max) was considerably lower than AFmax for hip flexors (62 N = similar to 28% AFmax) and elbow flexors (71 N = similar to 44% AFmax); i.e., maximal holding capacity was significantly reduced, indicating dysfunctional motor control. We tested PEMF at C7/T1, identified a frequency that improved neuromuscular function, and applied it for similar to 15 min. Immediately post-treatment, AFiso(max) increased to similar to 210 N (similar to 100% AFmax) at hip and 184 N (similar to 100% AFmax) at elbow. Subjective Long COVID symptoms resolved the following day. At 4 weeks post-treatment, maximal holding capacity was still on a similarly high level as for immediately post-treatment (similar to 100% AFmax) and patient was symptom-free. At 6 months the patient's Long COVID symptoms have not returned. This case report suggests (1) AF could be a promising diagnostic for post-infectious illness, (2) AF can be used to test effective treatments for post-infectious illness, and (3) individualized PEMF may resolve post-infectious symptoms.
This systematic review investigated how successful children/adolescents with poor literacy skills learn a foreign language compared with their peers with typical literacy skills. Moreover, we explored whether specific characteristics related to participants, foreign language instruction, and assessment moderated scores on foreign language tests in this population. Overall, 16 studies with a total of 968 participants (poor reader/spellers:n = 404; control participants:n = 564) met eligibility criteria. Only studies focusing on English as a foreign language were available. Available data allowed for meta-analyses on 10 different measures of foreign language attainment. In addition to standard mean differences (SMDs), we computed natural logarithms of the ratio of coefficients of variation (CVRs) to capture individual variability between participant groups. Significant between-study heterogeneity, which could not be explained by moderator analyses, limited the interpretation of results. Although children/adolescents with poor literacy skills on average showed lower scores on foreign language phonological awareness, letter knowledge, and reading comprehension measures, their performance varied significantly more than that of control participants. Thus, it remains unclear to what extent group differences between the foreign language scores of children/adolescents with poor and typical literacy skills are representative of individual poor readers/spellers. Taken together, our results indicate that foreign language skills in children/adolescents with poor literacy skills are highly variable. We discuss the limitations of past research that can guide future steps toward a better understanding of individual differences in foreign language attainment of children/adolescents with poor literacy skills.
Alcohol intoxication is known to affect many aspects of human behavior and cognition; one of such affected systems is articulation during speech production. Although much research has revealed that alcohol negatively impacts pronunciation in a first language (L1), there is only initial evidence suggesting a potential beneficial effect of inebriation on articulation in a non-native language (L2). The aim of this study was thus to compare the effect of alcohol consumption on pronunciation in an L1 and an L2. Participants who had ingested different amounts of alcohol provided speech samples in their L1 (Dutch) and L2 (English), and native speakers of each language subsequently rated the pronunciation of these samples on their intelligibility (for the L1) and accent nativelikeness (for the L2). These data were analyzed with generalized additive mixed modeling. Participants' blood alcohol concentration indeed negatively affected pronunciation in L1, but it produced no significant effect on the L2 accent ratings. The expected negative impact of alcohol on L1 articulation can be explained by reduction in fine motor control. We present two hypotheses to account for the absence of any effects of intoxication on L2 pronunciation: (1) there may be a reduction in L1 interference on L2 speech due to decreased motor control or (2) alcohol may produce a differential effect on each of the two linguistic subsystems.
Alcohol intoxication is known to affect many aspects of human behavior and cognition; one of such affected systems is articulation during speech production. Although much research has revealed that alcohol negatively impacts pronunciation in a first language (L1), there is only initial evidence suggesting a potential beneficial effect of inebriation on articulation in a non-native language (L2). The aim of this study was thus to compare the effect of alcohol consumption on pronunciation in an L1 and an L2. Participants who had ingested different amounts of alcohol provided speech samples in their L1 (Dutch) and L2 (English), and native speakers of each language subsequently rated the pronunciation of these samples on their intelligibility (for the L1) and accent nativelikeness (for the L2). These data were analyzed with generalized additive mixed modeling. Participants' blood alcohol concentration indeed negatively affected pronunciation in L1, but it produced no significant effect on the L2 accent ratings. The expected negative impact of alcohol on L1 articulation can be explained by reduction in fine motor control. We present two hypotheses to account for the absence of any effects of intoxication on L2 pronunciation: (1) there may be a reduction in L1 interference on L2 speech due to decreased motor control or (2) alcohol may produce a differential effect on each of the two linguistic subsystems.
Objective:
Depression and coronary heart disease (CHD) are highly comorbid conditions. Brain-derived neurotrophic factor (BDNF) plays an important role in cardiovascular processes. Depressed patients typically show decreased BDNF concentrations. We analysed the relationship between BDNF and depression in a sample of patients with CHD and additionally distinguished between cognitive-affective and somatic depression symptoms. We also investigated whether BDNF was associated with somatic comorbidity burden, acute coronary syndrome (ACS) or congestive heart failure (CHF).
Methods:
The following variables were assessed for 225 hospitalised patients with CHD: BDNF concentrations, depression [Patient Health Questionnaire-9 (PHQ-9)], somatic comorbidity (Charlson Comorbidity Index), CHF, ACS, platelet count, smoking status and antidepressant treatment.
Results:
Regression models revealed that BDNF was not associated with severity of depression. Although depressed patients (PHQ-9 score >7) had significantly lower BDNF concentrations compared to non-depressed patients (p = 0.04), this was not statistically significant after controlling for confounders (p = 0.15). Cognitive-affective symptoms and somatic comorbidity burden each closely missed a statistically significant association with BDNF concentrations (p = 0.08, p = 0.06, respectively). BDNF was reduced in patients with CHF (p = 0.02). There was no covariate-adjusted, significant association between BDNF and ACS.
Conclusion:
Serum BDNF concentrations are associated with cardiovascular dysfunction. Somatic comorbidities should be considered when investigating the relationship between depression and BDNF.
Objective:
Depression and coronary heart disease (CHD) are highly comorbid conditions. Brain-derived neurotrophic factor (BDNF) plays an important role in cardiovascular processes. Depressed patients typically show decreased BDNF concentrations. We analysed the relationship between BDNF and depression in a sample of patients with CHD and additionally distinguished between cognitive-affective and somatic depression symptoms. We also investigated whether BDNF was associated with somatic comorbidity burden, acute coronary syndrome (ACS) or congestive heart failure (CHF).
Methods:
The following variables were assessed for 225 hospitalised patients with CHD: BDNF concentrations, depression [Patient Health Questionnaire-9 (PHQ-9)], somatic comorbidity (Charlson Comorbidity Index), CHF, ACS, platelet count, smoking status and antidepressant treatment.
Results:
Regression models revealed that BDNF was not associated with severity of depression. Although depressed patients (PHQ-9 score >7) had significantly lower BDNF concentrations compared to non-depressed patients (p = 0.04), this was not statistically significant after controlling for confounders (p = 0.15). Cognitive-affective symptoms and somatic comorbidity burden each closely missed a statistically significant association with BDNF concentrations (p = 0.08, p = 0.06, respectively). BDNF was reduced in patients with CHF (p = 0.02). There was no covariate-adjusted, significant association between BDNF and ACS.
Conclusion:
Serum BDNF concentrations are associated with cardiovascular dysfunction. Somatic comorbidities should be considered when investigating the relationship between depression and BDNF.