Metal-Free Regioselective Monocyanation of Hydroxy-, Alkoxy-, and Benzyloxyarenes by Potassium Thiocyanate and Silica Sulfuric Acid as a Cyanating Agent
- A novel and efficient metal- and solvent-free regioselective para-C-H cyanation of hydroxy-, alkoxy-, and benzyloxyarene derivatives has been introduced, using nontoxic potassium thiocyanate as a cyanating reagent in the presence of silica sulfuric acid (SSA). The desired products are obtained in good to high yields without any toxic byproducts.
| Author details: | Ali Reza SardarianORCiD, Iman Dindarloo Inaloo, Ali Reza Modarresi-AlamORCiD, Erich KleinpeterORCiDGND, Uwe SchildeORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1021/acs.joc.8b02191 |
| ISSN: | 0022-3263 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/30624064 |
| Title of parent work (English): | The journal of organic chemistry |
| Publisher: | American Chemical Society |
| Place of publishing: | Washington |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2019 |
| Publication year: | 2019 |
| Release date: | 2021/04/07 |
| Volume: | 84 |
| Issue: | 4 |
| Number of pages: | 9 |
| First page: | 1748 |
| Last Page: | 1756 |
| Funding institution: | Research Council of Shiraz University |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| Peer review: | Referiert |
