Cytokines for evaluation of chronic inflammatory status in ageing research
- Background: There is a growing interest in the role of inflammageing for chronic disease development. Cytokines are potent soluble immune mediators that can be used as target biomarkers of inflammageing; however, their measurement in human samples has been challenging. This study aimed to assess the reliability of a pro- and anti-inflammatory cytokine panel in a sample of healthy people measured with a novel electrochemiluminescent multiplex immunoassay platform (Meso Scale Discovery, MSD), and to characterize their associations with metabolic and inflammatory phenotypes.
| Author details: | Liselot A. KoelmanORCiDGND, Olga Pivovarova-Ramich, Andreas F. H. PfeifferORCiDGND, Tilman GruneORCiDGND, Krasimira AleksandrovaORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1186/s12979-019-0151-1 |
| ISSN: | 1742-4933 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/31139232 |
| Title of parent work (German): | Immunity & Ageing |
| Subtitle (English): | reliability and phenotypic characterisation |
| Publisher: | BMC |
| Place of publishing: | London |
| Publication type: | Article |
| Language: | English |
| Date of first publication: | 2019/05/21 |
| Publication year: | 2019 |
| Release date: | 2021/06/18 |
| Tag: | Ageing; BMI; Biomarkers; Cytokines; Inflammaging; Multiplex platforms; Reliability |
| Volume: | 16 |
| Number of pages: | 12 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft |
| DDC classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Peer review: | Referiert |
| Publishing method: | Open Access / Gold Open-Access |
| DOAJ gelistet |
