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Dendritic polyglycerol-poly(ethylene glycol)-based polymer networks for biosensing application

  • This work describes the formation of a new dendritic polyglycerol-poly(ethylene glycol)-based 3D polymer network as a matrix for immobilization of the redox enzyme periplasmatic aldehyde oxidoreductase to create an electrochemical biosensor. The novel network is built directly on the gold surface, where it simultaneously stabilizes the enzyme for up to 4 days. The prepared biosensors can be used for amperometric detection of benzaldehyde in the range of 0.8-400 mu M.

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Author details:Pradip Dey, Miriam Adamovski, Simon Friebe, Artavazd BadalyanORCiDGND, Radu-Cristian Mutihac, Florian Paulus, Silke LeimkühlerORCiDGND, Ursula WollenbergerORCiDGND, Rainer HaagORCiDGND
DOI:https://doi.org/10.1021/am502018x
ISSN:1944-8244
Pubmed ID:https://pubmed.ncbi.nlm.nih.gov/24882361
Title of parent work (English):ACS applied materials & interfaces
Publisher:American Chemical Society
Place of publishing:Washington
Publication type:Article
Language:English
Year of first publication:2014
Publication year:2014
Release date:2017/03/27
Tag:amperometry; biosensors; dendritic; hydrogel
Volume:6
Issue:12
Number of pages:5
First page:8937
Last Page:8941
Funding institution:Cluster of Excellence "UniCAT" (Unifying Concepts in Catalysis, Berlin); graduate school "BIG NSE"; LB Brandenburg (Terasens)
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie
Peer review:Referiert
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