Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells

The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.

Metadaten
Author details:	T. Walter, Lena Collenburg, Lukasz Japtok GND, Burkhard Kleuser ORCiD GND, Sibylle Schneider-Schaulies ORCiD, N. Mueller, Jerome Becam, A. Schubert-Unkmeir, J. N. Kong, Erhard Bieberich, J. Seibel
DOI:	https://doi.org/10.1039/c6cc02879a
ISSN:	1359-7345
ISSN:	1364-548X
Pubmed ID:	https://pubmed.ncbi.nlm.nih.gov/27327378
Title of parent work (English):	Chemical communications
Publisher:	Royal Society of Chemistry
Place of publishing:	Cambridge
Publication type:	Article
Language:	English
Year of first publication:	2016
Publication year:	2016
Release date:	2020/03/22
Volume:	52
Number of pages:	3
First page:	8612
Last Page:	8614
Funding institution:	Deutsche Forschungsgemeinschaft [RU2123]; NIH [R01 R01AG034389, R56NS095215]
Organizational units:	Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft
Peer review:	Referiert