• search hit 10 of 128
Back to Result List

Separation of isomeric disaccharides by traveling wave ion mobility mass spectrometry using CO2 as drift gas

  • The use of CO2 as a massive and polarizable drift gas is shown to greatly improve peak-to-peak resolution (Rp-p), as compared with N2, for the separation of disaccharides in a Synapt G2 traveling wave ion mobility cell. Near or baseline Rp-p was achieved for three pairs of sodiated molecules of disaccharide isomers, that is, cellobiose and sucrose (Rp-p?=?0.76), maltose and sucrose (Rp-p?=?1.04), and maltose and lactose (Rp-p?=?0.74). Ion mobility mass spectrometry using CO2 as the drift gas offers therefore an attractive alternative for fast and efficient separation of isomeric disaccharides.

Export metadata

Additional Services

Share in Twitter Search Google Scholar Statistics
Metadaten
Author:Maira Fasciotti, Gustavo B. Sanvido, Vanessa G. Santos, Priscila M. Lalli, Michael McCullagh, Gilberto F. de Sa, Romeu J. Daroda, Martin G. Peter, Marcos N. Eberlin
DOI:https://doi.org/10.1002/jms.3089
ISSN:1076-5174 (print)
Parent Title (English):Journal of mass spectrometr
Publisher:Wiley-Blackwell
Place of publication:Hoboken
Document Type:Article
Language:English
Year of first Publication:2012
Year of Completion:2012
Release Date:2017/03/26
Tag:isomer resolution; oligosaccharides; polarizable drift gases; traveling wave ion mobility mass spectrometry
Volume:47
Issue:12
Pagenumber:5
First Page:1643
Last Page:1647
Funder:Brazilian science foundation FAPESP; Brazilian science foundation CNPq; Brazilian science foundation CAPES; Brazilian science foundation FINEP
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
Peer Review:Referiert