Ring-size-selective enyne metathesis as a tool for desymmetrization of an enantiopure C-2-symmetric building block
- The enantiomerically pure C-2-syrnmetrical hexa-1,5-diene-3,4-diol is selectively monopropargylated. The products undergo ring-closing enyne metathesis to give exclusively dihydropyrans as single stereoisomers. An unprotected hydroxy group is identified as the factor controlling the ring-size selectivity.
| Author details: | Bernd SchmidtORCiDGND, Lucia Staude |
|---|---|
| URL: | http://pubs.acs.org/journal/joceah |
| DOI: | https://doi.org/10.1021/Jo9018649 |
| ISSN: | 0022-3263 |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2009 |
| Publication year: | 2009 |
| Release date: | 2017/03/25 |
| Source: | The journal of organic chemistry. - ISSN 0022-3263. - 74 (2009), 23, S. 9237 - 9240 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
