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Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition

  • A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature.

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Author details:Jens Buller, André LaschewskyORCiDGND, Jean-Francois Lutz, Erik Wischerhoff
DOI:https://doi.org/10.1039/c1py00001b
ISSN:1759-9954
Title of parent work (English):Polymer Chemistry
Publisher:Royal Society of Chemistry
Place of publishing:Cambridge
Publication type:Article
Language:English
Year of first publication:2011
Publication year:2011
Release date:2017/03/26
Volume:2
Issue:7
Number of pages:4
First page:1486
Last Page:1489
Funding institution:The initiative "Spitzenforschung & Innovation in den neuen Landern" of the German Federal Ministry of Education and Research (BMBF) [03152201]
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
Peer review:Referiert
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