Detuning-dependent dominance of oscillation death in globally coupled synthetic genetic oscillators
- We study dynamical regimes of globally coupled genetic relaxation oscillators in the presence of small detuning. Using bifurcation analysis, we find that under strong coupling via the slow variable, the detuning can eliminate standard oscillatory solutions in a large region of the parameter space, providing the dominance of oscillation death. This result is substantially different from previous results on oscillation quenching, where for homogeneous populations, the coexistence of oscillation death and limit cycle oscillations is always present. We propose further that this effect of detuning-dependent dominance could be a powerful regulator of genetic network's dynamics.
| Author details: | Aneta Koseska, Evgenij Volkov, Jürgen KurthsORCiDGND |
|---|---|
| URL: | http://iopscience.iop.org/0295-5075/ |
| DOI: | https://doi.org/10.1209/0295-5075/85/28002 |
| ISSN: | 0295-5075 |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2009 |
| Publication year: | 2009 |
| Release date: | 2017/03/25 |
| Source: | Epl : Europhysics letters. - ISSN 0295-5075. - 85 (2009), 2, Art. 28002 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Physik und Astronomie |
| Peer review: | Referiert |
| Institution name at the time of the publication: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Physik |
