The search result changed since you submitted your search request. Documents might be displayed in a different sort order.
  • search hit 9 of 18
Back to Result List

Synthesis and conformational analysis of naphthylnaphthoxazine derivatives

  • Four new primary aminonaphthols (4, 5, 9 and 10) were synthesized from 1- or 2-naphthol and 1- or 2- naphthaldehyde via naphthoxazines in modified Mannich condensations. Simple ring-closure reactions of these aminonaphthols with paraformaldehyde, 4-nitrobenzaldehyde, phosgene or 4-chlorophenyl isothiocyanate led to new heterocyclic derivatives. In these transformations, either an sp2 or an sp3 carbon was inserted between the hydroxy and amino groups. The effects of substituents and the naphthyl ring on the conformation were investigated by means of NMR measurements, employing both dipolar and scalar couplings. The structures were confirmed by DFT quantum chemical calculations involving computed coupling constants, intramolecular distances between nuclei and the relative energies of the preferred conformers.

Export metadata

Additional Services

Search Google Scholar Statistics
Metadaten
Author details:Diána Thóth, István SzatmáriORCiD, Matthias HeydenreichORCiD, Andreas KochORCiDGND, Erich KleinpeterORCiDGND, Ferenc FulopORCiD
URL:http://www.sciencedirect.com/science/journal/00222860
DOI:https://doi.org/10.1016/j.molstruc.2009.04.015
ISSN:0166-1280
Publication type:Article
Language:English
Year of first publication:2009
Publication year:2009
Release date:2017/03/25
Source:Journal of molecular structure. - ISSN 0166-1280. - e-ISSN 0022-2860. - 929 (2009), 1-3, S. 58 - 66
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
Peer review:Referiert
Accept ✔
This website uses technically necessary session cookies. By continuing to use the website, you agree to this. You can find our privacy policy here.