Cyanobacteria as a source of natural products
- Cyanobacteria or blue-green algae from various environments have been recognized as sources of a variety of bioactive metabolites. Strategies of strain isolation from aquatic habitats, and cultivation and harvesting for metabolite production are described. Strategies for screening of compounds are discussed, including their direct MALDI-TOF mass spectrometric detection in whole cells. Genetic approaches including genomic mining, mutagenesis including transcriptional activation, heterologous expression, and in vitro. reconstitution of pathways are presented.
| Author details: | Martin Welker, Elke Dittmann-ThünemannORCiDGND, Hans von Doehren |
|---|---|
| DOI: | https://doi.org/10.1016/B978-0-12-404634-4.00002-4 |
| ISBN: | 978-0-12-404634-4 |
| ISSN: | 0076-6879 |
| Title of parent work (English): | Methods in enzymology |
| Title of parent work (English): | Methods in Enzymology |
| Publisher: | Elsevier |
| Place of publishing: | San Diego |
| Editor(s): | DA Hopwood |
| Publication type: | Review |
| Language: | English |
| Year of first publication: | 2012 |
| Publication year: | 2012 |
| Release date: | 2017/03/26 |
| Volume: | 517 |
| Issue: | 1 |
| Number of pages: | 24 |
| First page: | 23 |
| Last Page: | 46 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
| Peer review: | Referiert |
