Synthesis of polysarcosine from air and moisture stable N-phenoxycarbonyl-N-methylglycine assisted by tertiary amine base
- Polysarcosine (Mn = 3650–20 000 g mol−1, Đ ∼ 1.1) was synthesized from the air and moisture stable N-phenoxycarbonyl-N-methylglycine. Polymerization was achieved by in situ transformation of the urethane precursor into the corresponding N-methylglycine-N-carboxyanhydride, when in the presence of a non-nucleophilic tertiary amine base and a primary amine initiator.
Author details: | Afroditi Doriti, Sarah M. Brosnan, Steffen M. Weidner, Helmut SchlaadORCiDGND |
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DOI: | https://doi.org/10.1039/C6PY00221H |
ISSN: | 1759-9954 |
ISSN: | 1759-9962 |
Title of parent work (English): | Polymer Chemistry |
Publisher: | RSC Publ. |
Place of publishing: | Cambridge |
Publication type: | Article |
Language: | English |
Date of first publication: | 2016/04/08 |
Publication year: | 2016 |
Publishing institution: | Universität Potsdam |
Release date: | 2016/09/15 |
Tag: | acids; activated urethane derivatives; carboxyanhydrides; copolymers; phosgene-free synthesis; polypeptides; ring-opening polymerization |
Volume: | 7 |
First page: | 3067 |
Last Page: | 3070 |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Peer review: | Referiert |
Publishing method: | Open Access |
Grantor: | RSC |
License (English): | Creative Commons - Namensnennung 3.0 Unported |
External remark: | Zweitveröffentlichung in der Schriftenreihe Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe ; 255 |