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Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition

  • A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature.

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Author:Jens Buller, André LaschewskyORCiDGND, Jean-Francois Lutz, Erik Wischerhoff
ISSN:1759-9954 (print)
Parent Title (English):Polymer Chemistry
Publisher:Royal Society of Chemistry
Place of publication:Cambridge
Document Type:Article
Year of first Publication:2011
Year of Completion:2011
Release Date:2017/03/26
First Page:1486
Last Page:1489
Funder:The initiative "Spitzenforschung & Innovation in den neuen Landern" of the German Federal Ministry of Education and Research (BMBF) [03152201]
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie
Peer Review:Referiert