Synthesis and crystal structure of 1,4,10,13-tetraoxa-7,16-diazoniumcyclo-octadecane bis(4-chloro-2-methyl-phenoxyacetate)
- The title compound was prepared by the reaction of 1,4,10,13-tetraoxa-7,16-diazacyclo-octadecane with 4-chloro-2-methyl-phenoxyacetic acid in a ratio of 1:2. The structure has been proved by the data of elemental analysis, IR spectroscopy, NMR ( 1 H, 13 C) technique and by X-ray diffraction analysis. Intermolecular hydrogen bonds between the azonium protons and oxygen atoms of the carboxylate groups were found. Immunoactive properties of the title compound have been screened. The compound has the ability to suppress spontaneous and Con A-stimulated cell proliferation in vitro and therefore can be considered as immunodepressant.
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| Author details: | Sergey N. Adamovich, Anna N. Mirskova, Rudolf G. Mirskov, Uwe SchildeORCiDGND |
|---|---|
| URN: | urn:nbn:de:kobv:517-opus4-400905 |
| Publication series (Volume number): | Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (369) |
| Publication type: | Postprint |
| Language: | English |
| Date of first publication: | 2017/09/28 |
| Publication year: | 2017 |
| Publishing institution: | Universität Potsdam |
| Release date: | 2017/09/28 |
| Tag: | salts |
| Number of pages: | 4 |
| Source: | Chemistry Central Journal 5 (2011). - DOI: 10.1186/1752-153X-5-23 |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| Peer review: | Referiert |
| Publishing method: | Open Access |
| Grantor: | BioMed Central |
| License (German): |  Keine öffentliche Lizenz: Unter Urheberrechtsschutz |
