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Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) and the Risk of Developing Type 2 Diabetes

  • Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentrations and of differential methylation in the IGFBP-2 gene with type 2 diabetes risk.

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Author details:Clemens WittenbecherORCiDGND, Meriem Ouni, Olga Kuxhaus, Markus JähnertORCiD, Pascal GottmannORCiDGND, Andrea Teichmann, Karina Meidtner, Jennifer KriebelORCiD, Harald Grallert, Tobias PischonORCiD, Heiner BoeingORCiDGND, Matthias Bernd SchulzeORCiDGND, Annette SchürmannORCiDGND
DOI:https://doi.org/10.2337/db18-0620
ISSN:0012-1797
ISSN:1939-327X
Pubmed ID:https://pubmed.ncbi.nlm.nih.gov/30396904
Title of parent work (English):Diabetes : a journal of the American Diabetes Association
Publisher:American Diabetes Association
Place of publishing:Alexandria
Publication type:Article
Language:English
Year of first publication:2019
Publication year:2019
Release date:2021/05/28
Volume:68
Issue:1
Number of pages:10
First page:188
Last Page:197
Funding institution:Federal Ministry of Science, Germany [01 EA 9401]; European UnionEuropean Union (EU) [SOC 95201408 05 F02]; German Cancer AidDeutsche Krebshilfe [70-2488-Ha I]; European CommunityEuropean Community (EC) [SOC 98200769 05 F02]; German Federal Ministry of Education and Research (BMBF)Federal Ministry of Education & Research (BMBF) [82DZD00302]; State of Brandenburg
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft
DDC classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
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