Manganese(III)-mediated radical reactions in carbohydrate chemistry : a new route to 3-deoxy-D-manno-oct-2- ulosonic acid (KDO)
- An acyclic alkene derived from a carbohydrate is employed as a substrate for manganese-mediated radical reactions for the first time. The addition of malonate is interesting for the mechanism of such reactions, whereas acetic acid as radical precursor affords lactones in excellent yield. The main diastereomer was easily separated and represents a key intermediate in the synthesis of KDO
