Synthesis of chromanes through RCM-Transfer hydrogenation
- A sequential ruthenium-catalyzed ring-closing metathesis-transfer hydrogenation sequence has been established as a synthesis of chromanes starting from 2-(allyloxy)styrenes. The sequence requires only one precatalyst, the first-generation Grubbs catalyst, which is converted into a ruthenium hydride species in situ. Propan-2-ol serves as a chemical trigger for the formation of the ruthenium hydride and as hydrogen source.
| Author details: | Bernd SchmidtORCiDGND, Stefan Krehl, Veronica Sotelo-Meza |
|---|---|
| DOI: | https://doi.org/10.1055/s-0031-1289758 |
| ISSN: | 0039-7881 |
| Title of parent work (English): | Synthesis |
| Publisher: | Thieme |
| Place of publishing: | Stuttgart |
| Publication type: | Article |
| Language: | English |
| Year of first publication: | 2012 |
| Publication year: | 2012 |
| Release date: | 2017/03/26 |
| Tag: | chromanes; metathesis; ruthenium; styrenes; tandem reactions |
| Volume: | 44 |
| Issue: | 11 |
| Number of pages: | 11 |
| First page: | 1603 |
| Last Page: | 1613 |
| Funding institution: | Deutsche Forschungsgemeinschaft (DFG) [Schm 1095/6] |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| Peer review: | Referiert |
