- Background: Low birth weight (LBW) might be a risk factor for acquiring lower respiratory tract infections (LRTIs) associated with disease related complications in early childhood. HFMD, a frequent viral infection in southern China, is a leading cause of lower respiratory tract infections in children. We analyzed whether LBW is a risk factor for children with HFMD to develop lower respiratory tract infections.
Methods: A total of 298 children with HFMD, admitted to a hospital in Qingyuan city, Guangdong province, were recruited. Demographic data and clinical parameters such as serum glucose level and inflammatory markers including peripheral white blood cell count, serum C-reactive protein, and erythrocyte sedimentation rate were routinely collected on admission. Birth weight data were derived from birth records.
Results: Mean birth weight (BW) was 167 g lower in patients with HFMD and LRTIs as compared to patients with solely HFMD (p = 0.022) and the frequency of birth weight below the tenth percentile was significantly higher inBackground: Low birth weight (LBW) might be a risk factor for acquiring lower respiratory tract infections (LRTIs) associated with disease related complications in early childhood. HFMD, a frequent viral infection in southern China, is a leading cause of lower respiratory tract infections in children. We analyzed whether LBW is a risk factor for children with HFMD to develop lower respiratory tract infections.
Methods: A total of 298 children with HFMD, admitted to a hospital in Qingyuan city, Guangdong province, were recruited. Demographic data and clinical parameters such as serum glucose level and inflammatory markers including peripheral white blood cell count, serum C-reactive protein, and erythrocyte sedimentation rate were routinely collected on admission. Birth weight data were derived from birth records.
Results: Mean birth weight (BW) was 167 g lower in patients with HFMD and LRTIs as compared to patients with solely HFMD (p = 0.022) and the frequency of birth weight below the tenth percentile was significantly higher in patients with HFMD and LRTIs (p = 0.002).
Conclusions: The results of the study show that low birth weight is associated with a higher incidence of lower respiratory tract infections in young children with HFMD.…
MetadatenAuthor details: | Yong-Ping Lu, De-Ying Zeng, You-Peng Chen, Xu-Jing Liang, Jie-Ping Xu, Si-Min Huang, Zhi-Wei Lai, Wang-Rong Wen, Karoline von WebskyORCiDGND, Berthold HocherORCiDGND |
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DOI: | https://doi.org/10.7754/Clin.Lab.2012.120725 |
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ISSN: | 1433-6510 |
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Title of parent work (English): | Clinical laboratory : the peer reviewed journal for clinical laboratories and laboratories related to blood transfusion |
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Publisher: | Clin Lab Publ., Verl. Klinisches Labor |
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Place of publishing: | Heidelberg |
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Publication type: | Article |
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Language: | English |
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Year of first publication: | 2013 |
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Publication year: | 2013 |
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Release date: | 2017/03/26 |
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Tag: | children; foot and mouth disease (HFMD); hand; low birth weight (LBW); lower respiratory tract infections (LRTIs); pneumonia |
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Volume: | 59 |
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Issue: | 9-10 |
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Number of pages: | 8 |
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First page: | 985 |
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Last Page: | 992 |
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Funding institution: | Medical Scientific Research Foundation of Guangdong Province, China
[A2011348] |
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Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft |
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Peer review: | Referiert |
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