A regulatory role of autophagy for resetting the memory of heat stress in plants
- As sessile life forms, plants are repeatedly confronted with adverse environmental conditions, which can impair development, growth, and reproduction. During evolution, plants have established mechanisms to orchestrate the delicate balance between growth and stress tolerance, to reset cellular biochemistry once stress vanishes, or to keep a molecular memory, which enables survival of a harsher stress that may arise later. Although there are several examples of memory in diverse plants species, the molecular machinery underlying the formation, duration, and resetting of stress memories is largely unknown so far. We report here that autophagy, a central self-degradative process, assists in resetting cellular memory of heat stress (HS) in Arabidopsis thaliana. Autophagy is induced by thermopriming (moderate HS) and, intriguingly, remains high long after stress termination. We demonstrate that autophagy mediates the specific degradation of heat shock proteins at later stages of the thermorecovery phase leading to the accumulation ofAs sessile life forms, plants are repeatedly confronted with adverse environmental conditions, which can impair development, growth, and reproduction. During evolution, plants have established mechanisms to orchestrate the delicate balance between growth and stress tolerance, to reset cellular biochemistry once stress vanishes, or to keep a molecular memory, which enables survival of a harsher stress that may arise later. Although there are several examples of memory in diverse plants species, the molecular machinery underlying the formation, duration, and resetting of stress memories is largely unknown so far. We report here that autophagy, a central self-degradative process, assists in resetting cellular memory of heat stress (HS) in Arabidopsis thaliana. Autophagy is induced by thermopriming (moderate HS) and, intriguingly, remains high long after stress termination. We demonstrate that autophagy mediates the specific degradation of heat shock proteins at later stages of the thermorecovery phase leading to the accumulation of protein aggregates after the second HS and a compromised heat tolerance. Autophagy mutants retain heat shock proteins longer than wild type and concomitantly display improved thermomemory. Our findings reveal a novel regulatory mechanism for HS memory in plants.…
Author details: | Mastoureh SedaghatmehrORCiDGND, Venkatesh P. ThirumalaikumarORCiDGND, Iman KamranfarORCiDGND, Anne MarmagneORCiD, Celine Masclaux-DaubresseORCiD, Salma BalazadehORCiDGND |
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DOI: | https://doi.org/10.1111/pce.13426 |
ISSN: | 0140-7791 |
ISSN: | 1365-3040 |
Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/30136402 |
Title of parent work (English): | Plant, cell & environment : cell physiology, whole-plant physiology, community physiology |
Publisher: | Wiley |
Place of publishing: | Hoboken |
Publication type: | Article |
Language: | English |
Date of first publication: | 2019/08/22 |
Publication year: | 2019 |
Release date: | 2021/03/26 |
Tag: | Arabidopsis; heat shock proteins; priming; resetting |
Volume: | 42 |
Issue: | 3 |
Number of pages: | 11 |
First page: | 1054 |
Last Page: | 1064 |
Funding institution: | DAAD PROCOPE programme (PPP Frankreich) [57207509]; LabEx Saclay Plant Sciences-SPS [ANR-10-LABX-0040-SPS]; German Science Foundation (DFG), Collaborative Research Centre 973 "Priming and Memory of Organismic Responses to Stress" |
Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Biochemie und Biologie |
DDC classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
Peer review: | Referiert |