Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata
- From the seedpods of Tephrosia elata, a new β-hydroxydihydrochalcone named (S)-elatadihydrochalcone was isolated. In addition, the known flavonoids obovatachalcone, obovatin, obovatin methyl ether and deguelin were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids obtained from the seedpods of this plant showed antiplasmodial activities. The literature NMR data on β-hydroxydihydrochalcones is reviewed and the identity of some of the compounds assigned β-hydroxydihydrochalcone skeleton is questioned.
Verfasserangaben: | Martin G. Peter, Lois M. Muiva, Abiy YenesewORCiD, Solomon DereseORCiD, Matthias HeydenreichORCiD, Hoseah M. AkalaORCiD, Fredrick Eyase, Norman C. Waters, Charles Mutai, Joseph M. Keriko, Douglas S. Walsh |
---|---|
URN: | urn:nbn:de:kobv:517-opus-44437 |
Schriftenreihe (Bandnummer): | Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (paper 118) |
Publikationstyp: | Postprint |
Sprache: | Englisch |
Erscheinungsjahr: | 2009 |
Veröffentlichende Institution: | Universität Potsdam |
Datum der Freischaltung: | 05.07.2010 |
Freies Schlagwort / Tag: | (S)-Elatadihydrochalcone; Leguminosae; Seedpods; Tephrosia elata; β-Hydroxydihydrochalcone |
Quelle: | Phytochemistry letters 2 (2009), 3, S. 99 - 102, DOI 10.1016/j.phytol.2009.01.002 |
Organisationseinheiten: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
DDC-Klassifikation: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Lizenz (Deutsch): | Keine öffentliche Lizenz: Unter Urheberrechtsschutz |
Externe Anmerkung: | The article was originally published by: Elsevier Phytochemistry letters. - 2 (2009), 3, S. 99-102 ISSN 1874-3900 DOI 10.1016/j.phytol.2009.01.002 |