The search result changed since you submitted your search request. Documents might be displayed in a different sort order.
  • search hit 18 of 27
Back to Result List

Increase of urate formation by stimulation of sympathetic hepatic nerves, circulating noradrenaline and glucagon inthe perfused rat liver

  • In the isolated rat liver perfused in situ stimulation of the nerve bundles around the portal vein and the hepatic artery caused an increase of urate formation that was inhibited by the α1-blocker prazosine and the xanthine oxidase inhibitor allopurinol. Moreover, nerve stimulation increased glucose and lactate output and decreased perfusion flow. Infusion of noradrenaline had similar effects. Compared to nerve stimulation infusion of glucagon led to a less pronounced increase of urate formation and a twice as large increase in glucose output but a decrease in lactate release without affecting the flow rate. Insulin had no effect on any of the parameters studied.

Download full text files

Export metadata

Additional Services

Search Google Scholar Statistics
Metadaten
Author details:Gerhard Paul PüschelORCiDGND, Annegret Nath, Kurt Jungermann
URN:urn:nbn:de:kobv:517-opus-16728
Publication series (Volume number):Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (paper 038)
Publication type:Postprint
Language:English
Publication year:1987
Publishing institution:Universität Potsdam
Release date:2008/03/14
Tag:Allantoin; Catecholamine; Glucagon; Hepatic nerve; Urate
Source:FEBS Letters 219 (1987), 1, p. 145 - 150 , DOI 10.1016/0014-5793(87)81207-3, ISSN 0014-5793
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft
Extern / Extern
DDC classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
License (German):License LogoKeine öffentliche Lizenz: Unter Urheberrechtsschutz
External remark:
first published in:
FEBS Letters - 219 (1987), 1, p. 145-150
ISSN: 0014-5793
doi: 10.1016/0014-5793(87)81207-3
Accept ✔
This website uses technically necessary session cookies. By continuing to use the website, you agree to this. You can find our privacy policy here.