Stereoselective synthesis of conjugated polyenes based on tethered olefin metathesis and carbonyl olefination
- The combination of a highly stereoselective tethered olefin metathesis reaction and a Julia-Kocienski olefination is presented as a strategy for the synthesis of conjugated polyenes with at least one Z-configured C=C bond. The strategy is exemplified by the synthesis of the marine natural product (+)-bretonin B.
| Author details: | Kajsa LoodGND, Bernd SchmidtORCiDGND |
|---|---|
| DOI: | https://doi.org/10.1021/acs.joc.0c00446 |
| ISSN: | 0022-3263 |
| ISSN: | 1520-6904 |
| Pubmed ID: | https://pubmed.ncbi.nlm.nih.gov/32162517 |
| Title of parent work (English): | The journal of organic chemistry |
| Subtitle (English): | application to the total synthesis of (+)-bretonin B |
| Publisher: | American Chemical Society |
| Place of publishing: | Washington |
| Publication type: | Article |
| Language: | English |
| Date of first publication: | 2020/03/12 |
| Publication year: | 2020 |
| Release date: | 2022/11/30 |
| Tag: | absolute-configuration; alcohols; aldehydes; catalysts; derivatives; ethers; formal synthesis; natural-products; oxidation; sponge |
| Volume: | 85 |
| Issue: | 7 |
| Number of pages: | 9 |
| First page: | 5122 |
| Last Page: | 5130 |
| Funding institution: | Deutsche Forschungsgemeinschaft (DFG)German Research Foundation (DFG); [Schm1095/6-2] |
| Organizational units: | Mathematisch-Naturwissenschaftliche Fakultät / Institut für Chemie |
| DDC classification: | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
| 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit | |
| Peer review: | Referiert |
