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Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells

  • The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.

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Author:Tim Walter, Lena Collenburg, Lukasz Japtok, Burkhard KleuserORCiDGND, Sibylle Schneider-Schaulies, Nora Müller, Jerome Becam, Alexandra Schubert-Unkmeir, Ji Na Kong, Erhard Bieberich, Jürgen Seibel
Series (Serial Number):Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe (324)
Document Type:Postprint
Date of first Publication:2016/06/16
Year of Completion:2016
Publishing Institution:Universität Potsdam
Release Date:2017/04/21
Source:Chem.Commun. (2016) Nr. 52, S. 8612-8614. - DOI: 10.1039/C6CC02879A
Organizational units:Mathematisch-Naturwissenschaftliche Fakultät / Institut für Ernährungswissenschaft
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Peer Review:Referiert
Publication Way:Open Access
Licence (English):License LogoCreative Commons - Attribution 3.0 unported